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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:25 PM IST
Eflemac 600mg Tablet is used to treat HIV infection. It contains Efavirenz which works by interfering with the normal working of enzymes that are essential for virus reproduction. In some cases, this medicine may cause side effects such as trouble sleeping, drowsiness, dizziness, unusual dreams and trouble concentrating. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

EFAVIRENZ-600MG

Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Eflemac 600mg Tablet

Eflemac 600mg Tablet belongs to the group of medications called ‘antiretroviral drugs’ used to treat HIV infection in adults and children of at least 3 months old and weighing at least 3.5 kg. The human immunodeficiency virus (HIV) is a sexually transmitted infection that over time leads to acquired immunodeficiency syndrome (AIDS). Eflemac 600mg Tablet is used with other medicines to control and reduce the amount of HIV in the body so that the immune system can work in a good way.

Eflemac 600mg Tablet contains 'Efavirenz' which is a ‘nucleotide reverse transcriptase inhibitor’ and works by interfering with the normal working of enzymes (reverse transcriptase in HIV ) that are essential for the production of viruses. It can effectively reduce the symptoms associated with HIV.

Take Eflemac 600mg Tablet as prescribed by your doctor. You are suggested to take Eflemac 600mg Tablet as long as your doctor has prescribed it after checking your medical condition. The common side effects of Eflemac 600mg Tablet are trouble sleeping, drowsiness, dizziness, unusual dreams and trouble concentrating. However, seek medical attention if the side effects persist.

Do not take Eflemac 600mg Tablet if you are allergic to Eflemac 600mg Tablet or any other contents present in it. Eflemac 600mg Tablet should be used with caution in patients with severe liver and kidney diseases. Consult a doctor immediately if you develop any new signs of infection while using this medicine. Inform your doctor if you are pregnant, planning to become pregnant and breastfeeding. It is important to monitor liver functions during the treatment, in persons with liver disease including hepatitis B or C infection. Older adults are sensitive to the side effects of Eflemac 600mg Tablet, so dosage adjustment is required.

Uses of Eflemac 600mg Tablet

Treatment of Human immunodeficiency virus (HIV).

Medicinal Benefits

Eflemac 600mg Tablet is used with other medicines to control and treat HIV infection. This medicine helps to reduce the amount of HIV, which in turn improves the natural defense system(immune system ) of the body. When a person takes Eflemac 600mg Tablet, it goes into their bloodstream and interferes with the action of an enzyme ( reverse transcriptase (RT)), that is used by HIV infected cells for their growth and making new viruses. HIV destroys the white cells of the body that are important for protecting the body from other infections. Eflemac 600mg Tablet slows down the destruction of these white cells and stops the virus from copying it. By inhibiting the activity of this enzyme, Eflemac 600mg Tablet helps to lower the risk of getting serious infections associated with HIV and allows a person to live a normal life.

Directions for Use

Take Eflemac 600mg Tablet as advised by your doctor. Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Eflemac 600mg Tablet

  • Rash
  • Dizziness
  • Confusion
  • Insomnia
  • Headaches
  • diarrhea
  • Nausea
  • Vomiting
  • Muscle pain (myalgia)
  • Abnormal heartbeats
  • Liver failure
  • Increased cholesterol increased triglyceride levels
  • Drowsiness
  • Abnormal dreams
  • Hallucinations
  • Difficulty concentrating

Drug Warnings

Eflemac 600mg Tablet is not a complete treatment of HIV infection however this medicine helps to reduce the HIV in the body so that the immune system of the body can protect the body from other infections associated with a weak immune system. To reduce the chance of spreading HIV to others it is suggested to keep taking all the HIV medicines suggested by your doctor. Use an effective contraceptive method during sexual activity and never share your personal items like needles, syringes toothbrushes with anyone as these products may have liquid with HIV. This medicine contains lactose, so inform your doctor if you have an intolerance to any sugars. 

Drug Interactions

Drug-Drug interactions: Eflemac 600mg Tablet may interact with a medication used to treat chronic hepatitis C (paritaprevir/ritonavir/dasabuvir/ombitasvir), antifungals (itraconazole, ketoconazole), macrolide antibiotics (clarithromycin), cholesterol-lowering statins (atorvastatin, pravastatin, simvastatin), and protease inhibitors (boceprevir, simeprevir) and drugs to treat HIV infection (elvitegravir).

Drug-Food interactions: Avoid high fatty meals as it may reduce the absorption of the drug in the body. 

Drug-Disease interactions: Eflemac 600mg Tablet should be used with caution in patients with severe heart, liver or kidney diseases.

Drug-Drug Interactions Checker List

  • PARITAPREVIR
  • RITONAVIR
  • DASABUVIR
  • OMBITASVIR
  • ITRACONAZOLE
  • KETOCONAZOLE
  • CLARITHROMYCIN
  • ATORVASTATIN
  • PRAVASTATIN
  • SIMVASTATIN
  • BOCEPREVIR
  • SIMEPREVIR
  • GANCICLOVIR
  • CIDOFOVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a diet with fresh fruits and vegetables.
  • Opt for lean meat such as skinless chicken and fish. Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Special Advise

  • Your doctor may regularly monitor liver function, kidney function and bone density if you take Eflemac 600mg Tablet.
  • Reliable method of contraceptives should be used to prevent pregnancy while using Eflemac 600mg Tablet.

Disease/Condition Glossary

Human immunodeficiency syndrome (HIV): It is a virus that suppresses the immune system and causes acquired immunodeficiency syndrome (AIDS) over time. The suppression of immunity leads to the development of opportunistic infections. It is a life-long condition and there is no permanent cure. The treatment (antiretroviral therapy) is given to suppress the infection. If the right treatment is not provided, then it may affect and kill immune cells which can put the body at high risk of getting serious infections. HIV can transfer from one person to another by blood, vaginal and rectal fluids, breast milk and semen.

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Alcohol

Caution

It is advised to avoid consuming alcohol as it may worsen the condition.

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Pregnancy

Caution

Eflemac 600mg Tablet is a category B medicine. It should be used with caution in pregnant women as Eflemac 600mg Tablet may pass into breastmilk, which can transmit HIV to baby, so do not breastfeed your child.

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Breast Feeding

Caution

Eflemac 600mg Tablet should only be used in breastfeeding females if prescribed by the doctor.

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Driving

Caution

Eflemac 600mg Tablet may cause dizziness. So, avoid driving or refrain from any activities that require you to alert mentally.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Unsafe

Eflemac 600mg Tablet should not be used in adolescents with kidney failure. In other people with severe kidney diseases, Eflemac 600mg Tablet is given only if clinically needed and suggested by the doctor.

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Children

Safe if prescribed

Eflemac 600mg Tablet is safe to be used in children only if suggested by the doctor depending upon the age and weight of the child.

Country of origin

India
Other Info - EF88512

Author Details

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FAQs

Eflemac 600mg Tablet is used to treat HIV infection.
Eflemac 600mg Tablet is not a complete treatment of HIV infection however this medicine helps to reduce the HIV in the body so that the immune system of the body can protect the body from other infections associated with a weak immune system.
To reduce the chance of spreading HIV to others it is suggested to keep taking all the HIV medicines suggested by your doctor. Use an effective contraceptive method during sexual activity and never share your personal items like needles, syringes, toothbrushes with anyone as these products may have liquid with HIV.
Eflemac 600mg Tablet contains "Efavirenz" which is a ‘nucleotide reverse transcriptase inhibitor’ and works by interfering with the normal working of enzymes (reverse transcriptase in HIV) that are essential for the production of viruses. It can effectively reduce the symptoms associated with HIV.
Eflemac 600mg Tablet does not affect fertility. However, if you develop any side-effects while using Eflemac 600mg Tablet, consult your doctor immediately.
Eflemac 600mg Tablet should be taken as prescribed by your doctor. Abrupt stopping of this medicine may lead to resistance to other medications making the infection difficult to treat.
Eflemac 600mg Tablet may cause dizziness. So, it would be best if you refrained from driving or operating heavy machinery that requires you to stay alert.
Eflemac 600mg Tablet may alter kidney function. So, it is used with caution in patients with kidney failure, especially adolescents.
Eflemac 600mg Tablet belongs to a group of medications known as 'antiretroviral drugs'. It is used to treat HIV infection in adults and children aged at least 3 months and weighing 3.5 kg or more. It contains 'Efavirenz,' a nucleotide reverse transcriptase inhibitor, which works by blocking the activity of the reverse transcriptase enzyme essential for HIV replication. This helps to reduce the symptoms associated with HIV and slows the progression of the infection.
Yes, Eflemac 600mg Tablet is safe if taken in the dose and duration exactly as prescribed by the doctor.
Yes, Eflemac 600mg Tablet is effective in managing HIV infection when used as part of a combination antiretroviral therapy (ART). It helps reduce the viral load in the body, increases the count of CD4 cells (a type of white blood cell that fights infections), and slows the progression of the disease. However, its effectiveness depends on following the prescribed treatment plan and regular follow-ups with the doctor.
If you forget to take a dose of Eflemac 600mg Tablet, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Eflemac 600mg Tablet is generally not recommended during pregnancy, especially in the first trimester, as it may cause harm to the developing baby. Consult the doctor before taking Eflemac 600mg Tablet, If you are pregnant, planning to become pregnant or think you might be pregnant. The doctor will evaluate the risks and benefits and may suggest alternative medications if necessary.
The side effects of Eflemac 600mg Tablet include trouble sleeping, dizziness, drowsiness, unusual dreams and difficulty concentrating. Consult the doctor if any of these side effects persist or worsen.

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