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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dysport 500 Injection is used for muscle relaxation and the symptomatic treatment of upper limb spasticity in paediatric cerebral palsy patients aged two years or older. It contains Clostridium botulinum type A toxin haemagglutinin complex, which acts on the junctions between the nerves and muscles, preventing the release of acetylcholine (a chemical messenger) from the nerve endings that would generally cause the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.

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Manufacturer/Marketer :

Bharat Serums and Vaccines Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Dysport 500 Injection

Dysport 500 Injection belongs to a group of medicines called muscle relaxants used to treat upper limb spasticity, lower limb spasticity, spasmodic torticollis (neck muscle contraction), blepharospasm (abnormal contraction of the eyelid muscles), hemifacial spasm (contractions or spasms of the muscles on one side of the face), moderate to severe glabellar lines (worry lines), and moderate to severe lateral canthal line (crow's feet or laugh lines).

Dysport 500 Injection contains Clostridium botulinum type A toxin haemagglutinin complex, which acts on the junctions between the nerves and muscles, preventing the release of acetylcholine (a chemical messenger) from the nerve endings that would normally cause the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.

In some cases, Dysport 500 Injection may cause injection site reactions, headache, tiredness, generalised weakness, and flu-like symptoms. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Dysport 500 Injection. Dysport 500 Injection should not be used during pregnancy or lactation. Dysport 500 Injection may cause muscle weakness or visual disturbances; therefore, drive only if you are alert. Inform the doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Dysport 500 Injection

Used for Muscle relaxation and the symptomatic treatment of upper limb spasticity in paediatric cerebral palsy patients aged two years or older

Directions for Use

Dysport 500 Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Dysport 500 Injection belongs to a group of medicines called muscle relaxants used to treat upper limb spasticity, lower limb spasticity, spasmodic torticollis (neck muscle contraction), blepharospasm (abnormal contraction of the eyelid muscles), hemifacial spasm (contractions or spasms of the muscles on one side of the face), moderate to severe glabellar lines (worry lines), and moderate to severe lateral canthal line (crow's feet or laugh lines). Dysport 500 Injection contains Clostridium botulinum type A toxin haemagglutinin complex, which acts on the junctions between the nerves and muscles, preventing the release of acetylcholine (a chemical messenger) from the nerve endings that would normally cause the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.

How Dysport 500 Injection Works

Dysport 500 Injection contains Clostridium botulinum type A toxin haemagglutinin complex, which acts on the junctions between the nerves and muscles, preventing the release of acetylcholine (a chemical messenger) from the nerve endings that would normally cause the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dysport 500 Injection

  • Headache
  • Injection site reactions (pain, redness, swelling)
  • Tiredness
  • Generalised weakness
  • Flu-like symptoms

What if I have taken an overdose of Dysport 500 Injection

As Dysport 500 Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not use Dysport 500 Injection if you are allergic to any of its components, if you have an infection at the proposed site of injection, myasthenia gravis (muscle problems), Eaton-Lambert Syndrome (neuromuscular junction disorder affecting communication between nerves and muscles), or amyotrophic lateral sclerosis (nervous system disease that weakens muscles). Inform the doctor if you have any neuromuscular disorders, dysphagia (difficulty swallowing food), weak muscles at the proposed site of injection, problems with food or drink getting into your airways, causing you to cough or choke, or bleeding disorders. Dysport 500 Injection should not be used during pregnancy or lactation. Dysport 500 Injection may cause muscle weakness or visual disturbances; therefore, drive only if you are alert. Let the doctor know if you have had surgery on your face or are likely to undergo facial or other types of surgery soon.

Drug-Drug Interactions

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Botulinum toxinClindamycin
Severe
Botulinum toxinNeomycin
Severe

Drug-Drug Interactions

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Botulinum toxinClindamycin
Severe
How does the drug interact with Dysport 500 Injection 1's:
Taking Clindamycin with Dysport 500 Injection 1's can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clindamycin with Dysport 500 Injection 1's together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Botulinum toxinNeomycin
Severe
How does the drug interact with Dysport 500 Injection 1's:
Coadministration of Dysport 500 Injection 1's with Neomycin may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection 1's and neomycin, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinTubocurarine
Severe
How does the drug interact with Dysport 500 Injection 1's:
Using Dysport 500 Injection 1's with Tubocurarine may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection 1's and tubocurarine, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinDoxacurium chloride
Severe
How does the drug interact with Dysport 500 Injection 1's:
Using Dysport 500 Injection 1's with Doxacurium chloride may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection 1's and Doxacurium chloride, it can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinKanamycin
Severe
How does the drug interact with Dysport 500 Injection 1's:
Coadministration of Dysport 500 Injection 1's with Kanamycin can make it more effective for therapy.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection 1's and Kanamycin, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinFlurbiprofen
Severe
How does the drug interact with Dysport 500 Injection 1's:
Using Flurbiprofen with Dysport 500 Injection 1's can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Flurbiprofen with Dysport 500 Injection 1's can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience vomiting, irregular urination, swelling, muscle cramps, or weakness, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Botulinum toxinVecuronium
Severe
How does the drug interact with Dysport 500 Injection 1's:
Using Dysport 500 Injection 1's and vecuronium together may increase the risk of certain side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection 1's and Vecuronium, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience any side effects like muscle weakness, trouble breathing, or swallowing. Do not discontinue any medications without consulting a doctor.
Botulinum toxinCisatracurium
Severe
How does the drug interact with Dysport 500 Injection 1's:
Using Dysport 500 Injection 1's with Cisatracurium may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection 1's and Cisatracurium, they can be taken together if prescribed by a doctor. However, if you experience muscle weakness or trouble breathing, swallowing, or speaking, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Botulinum toxinMivacurium chloride
Severe
How does the drug interact with Dysport 500 Injection 1's:
Coadministration of Dysport 500 Injection 1's with Mivacurium chloride can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection 1's and Mivacurium chloride, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinSpectinomycin
Severe
How does the drug interact with Dysport 500 Injection 1's:
Coadministration of Dysport 500 Injection 1's with Spectinomycin may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection 1's and Spectinomycin, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to be healthy by eating proper food and exercising regularly.
  • Avoid smoking and alcohol consumption.
  • Stay hydrated.
  • Rest properly; get optimum sleep.

Habit Forming

No

Therapeutic Class

MUSCLE RELAXANTS
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Alcohol

Consult your doctor

It is not known if alcohol affects Dysport 500 Injection. Please consult a doctor.

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Pregnancy

Unsafe

Dysport 500 Injection is not recommended for use during pregnancy. Consult the doctor if you are pregnant, planning for pregnancy or think you may be pregnant.

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Breast Feeding

Unsafe

Dysport 500 Injection is not recommended for use during lactation. Please consult the doctor if you are breastfeeding.

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Driving

Caution

Dysport 500 Injection may cause visual disturbances or muscle weakness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Dysport 500 Injection can be used for the treatment of upper and lower limb spasticity in children above two years. It should not be used for other conditions in children.

FAQs

Dysport 500 Injection is used for Muscle relaxation and the symptomatic treatment of upper limb spasticity in paediatric cerebral palsy patients aged two years or older.
Dysport 500 Injection prevents the release of acetylcholine, a chemical messenger that causes the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.
Dysport 500 Injection may cause injection site reactions like pain, burning, tingling, redness, bruising, rash, itching, stinging, irritation, or discomfort. If the conditions persist or worsen, consult the doctor.
Dose adjustment may be needed in the elderly where reduced muscle mass may exist. Talk to the doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

17Th Floor, Hoechst House, Nariman Point, Mumbai 400 021, Maharashtra, India.
Other Info - DYS0025

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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