apollo
0
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dutalfa Combipack is used to treat benign prostatic hyperplasia (enlarged prostate gland). It contains Alfuzosin and Dutasteride which work by relaxing the prostate gland muscles and reducing the prostate gland size by lowering the production of dihydrotestosterone hormone. In some cases, this medicine may cause side effects such as dizziness, sexual problems, runny/stuffy nose, or lightheadedness. Inform the doctor if you are taking any other medication, or have any pre-existing medical conditions.

Read more
rxMedicinePrescription drug

Whats That

tooltip

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Dutalfa Combipack

Dutalfa Combipack belongs to a group of medicines known as 'urinary bladder relaxant' medication, used primarily in treating the enlarged prostate gland. Benign prostatic hyperplasia (enlarged prostate gland) is a non-cancerous growth of the prostate gland caused by the overproduction of a dihydrotestosterone hormone in men. As the gland enlarges, it can lead to urinary problems, such as difficulty passing urine and frequent urination. Dutalfa Combipack helps relieve these symptoms. Dutalfa Combipack does not cure prostate cancer.

Dutalfa Combipack contains Alfuzosin (alpha-blockers) and Dutasteride (5-alpha reductase inhibitor), primarily used to treat the enlarged prostate gland. Alfuzosin makes it easy to pass urine by relaxing the prostate gland muscles. Dutasteride reduces the enlarged prostate gland's size by lowering the production of dihydrotestosterone hormone, thereby relieving urinary incontinence symptoms that minimise the need for prostate surgery and the risk of acute urinary retention. Both of them collectively improve Benign Hyperplasia Prostate symptoms (BPH).

You are advised to take Dutalfa Combipack for as long as your doctor has prescribed it for you, depending upon your medical condition. The most common side effects of Dutalfa Combipack are dizziness, lightheadedness, drowsiness, sexual problems (decreased sex drive or libido), runny/stuffy nose, reduced amount of semen/sperm, testicle pain/swelling, increased breast size, or breast tenderness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. 

Women or children should not take Dutalfa Combipack. Please inform your doctor before starting Dutalfa Combipack if you have low blood pressure, liver/kidney disease, or a history of heart problems. It is advisable to use contraceptives (like a condom) while having sex if your wife is pregnant as Dutalfa Combipack is known to pass in semen. Do not donate blood while taking Dutalfa Combipack. However, you can donate it six months after the last dose of Dutalfa Combipack.

Uses of Dutalfa Combipack

Treatment of Benign prostatic hyperplasia (BPH)

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Dutalfa Combipack contains Alfuzosin (alpha-blockers) and dutasteride (5-alpha reductase inhibitor), primarily used in treating the enlarged prostate gland. As the gland enlarges, it can lead to urinary problems, such as difficulty passing urine and a frequent urination urge. Dutasteride lowers the production of dihydrotestosterone hormone, which leads to a decrease in the size of the prostate and, as a result, relieves the symptoms. This will reduce the risk of acute urinary retention and the need for surgery. Alfuzosin makes it easy to pass urine by relaxing the muscles of the gland. Both of them collectively improve Benign Hyperplasia Prostate symptoms (BPH).

How Dutalfa Combipack Works

Dutalfa Combipack contains Alfuzosin (alpha-blockers) and Dutasteride (5-alpha reductase inhibitor), primarily used to treat the enlarged prostate gland. Alfuzosin makes it easy to pass urine by relaxing the prostate gland muscles. Dutasteride reduces the enlarged prostate gland's size by lowering the production of dihydrotestosterone hormone, thereby relieving urinary incontinence symptoms that minimise the need for prostate surgery and the risk of acute urinary retention. Both of them collectively improve Benign Hyperplasia Prostate symptoms (BPH).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dutalfa Combipack

  • Impotence (not able to achieve or maintain an erection)
  • Decreased sex drive (libido)
  • Difficulty with ejaculation 
  • Gynecomastia (breast enlargement or tenderness)
  • Dizziness
  • Breast tenderness
  • Problems with ejaculation 

What if I have taken an overdose of Dutalfa Combipack

Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Dutalfa Combipack if you are allergic to any of its ingredients. Dutalfa Combipack should not be taken if you have low blood pressure, which makes you feel dizzy, lightheaded, or faint, or if you have glaucoma. Inform your doctor if you have a history of heart disease or liver/kidney disease. Before undergoing surgery (cataract), please consult a doctor, as you might be advised to stop Dutalfa Combipack. During sexual intercourse, use a condom as Dutalfa Combipack is found in semen. Contact your doctor for advice if you are pregnant or plan to get pregnant before taking Dutalfa Combipack as it may affect the development of male genitals. Also, keep your doctor informed about all the OTC medicines you use. Patients taking Dutalfa Combipack should be cautioned about driving, operating machinery, or performing hazardous tasks, as it can cause drowsiness or dizziness. In rare cases, problems of penis erection, ejaculation, and pain in the penis can occur. So, if these symptoms last for a longer time, immediately contact your doctor.

Drug-Drug Interactions

verifiedApollotooltip
AlfuzosinVoriconazole
Critical
AlfuzosinErythromycin
Critical

Drug-Drug Interactions

Login/Sign Up

AlfuzosinVoriconazole
Critical
How does the drug interact with Dutalfa Combipack 1's:
Using Dutalfa Combipack 1's together with voriconazole may significantly increase the blood levels and effects of Dutalfa Combipack 1's.

How to manage the interaction:
Taking Voriconazole with Dutalfa Combipack 1's is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, headache, nasal congestion, or heart palpitation. Do not stop using any medications without talking to a doctor.
AlfuzosinErythromycin
Critical
How does the drug interact with Dutalfa Combipack 1's:
When Dutalfa Combipack 1's is taken with erythromycin, this can cause your blood pressure to fall excessively and your heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Taking erythromycin with Dutalfa Combipack 1's is not recommended as it can result in an interaction, but it should be taken if your doctor has advised it. However, if you experience dizziness, headache, or shortness of breath, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinKetoconazole
Critical
How does the drug interact with Dutalfa Combipack 1's:
Using Dutalfa Combipack 1's together with ketoconazole may significantly increase the blood levels of Dutalfa Combipack 1's, which may result in side effects.

How to manage the interaction:
Taking Dutalfa Combipack 1's with Ketoconazole is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fainting, headache, flushing, nasal congestion, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinTipranavir
Critical
How does the drug interact with Dutalfa Combipack 1's:
When Dutalfa Combipack 1's and Tipranavir are taken together, the body's ability to break down Dutalfa Combipack 1's may be reduced. This increases the risk and severity of side effects.

How to manage the interaction:
Taking Dutalfa Combipack 1's with Tipranavir is not recommended as it can possibly result in an interaction. It should be taken only when advised by a doctor. However, if you experience symptoms like severe dizziness, fainting, fast/irregular heartbeat, chest pain, fast or irregular heartbeat, nausea, or sweating contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinClarithromycin
Critical
How does the drug interact with Dutalfa Combipack 1's:
When Dutalfa Combipack 1's and Clarithromycin can increase the risk or severity of side effects like low blood pressure or irregular heart rates.

How to manage the interaction:
Taking clarithromycin with Dutalfa Combipack 1's is not recommended as it can result in an interaction; it should be taken only if your doctor has advised it. However, if you experience dizziness, headache, palpitations, or chest discomfort, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinThioridazine
Critical
How does the drug interact with Dutalfa Combipack 1's:
Taking Dutalfa Combipack 1's with Thioridazine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dutalfa Combipack 1's with Thioridazine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinTelaprevir
Critical
How does the drug interact with Dutalfa Combipack 1's:
Taking Telaprevir with Dutalfa Combipack 1's can increase the blood levels and effects of Dutalfa Combipack 1's. This can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Telaprevir with Dutalfa Combipack 1's is not recommended as it can possibly result in an interaction, it can be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinDronedarone
Critical
How does the drug interact with Dutalfa Combipack 1's:
Coadministration of Dronedarone with Dutalfa Combipack 1's can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dronedarone with Dutalfa Combipack 1's together is not recommended, as it leads to an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, shortness of breath, chest discomfort, or palpitations, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinIdelalisib
Critical
How does the drug interact with Dutalfa Combipack 1's:
When Idelalisib is taken with Dutalfa Combipack 1's, it can lower the metabolism of Dutalfa Combipack 1's. This can increase the risk or severity of side effects like low blood pressure.

How to manage the interaction:
Taking Dutalfa Combipack 1's with Idelalisib is not recommended as it can possibly result in an interaction, it should be taken only if your doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection), contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinAtazanavir
Critical
How does the drug interact with Dutalfa Combipack 1's:
Concomitant use of Dutalfa Combipack 1's with Atazanavir can increase the risk of low blood pressure.

How to manage the interaction:
Coadministration of Dutalfa Combipack 1's with Atazanavir is not recommended, however, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience dizziness, palpitations, difficulty swallowing, or sweating. It is recommended to monitor your blood pressure regularly. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Avoid drinking alcohol, caffeine, and fizzy drinks. Limit intake of artificial sweeteners.
  • Maintain a healthy lifestyle and exercise regularly so you do not feel heavy in the abdomen.
  • Also, drink less water in the evening and before sleeping to have a sound sleep and not wake up frequently for urination.
  • Any medication that may worsen urinary symptoms (for cold and cough) should be avoided.

Habit Forming

No

Therapeutic Class

ALPHA BLOCKERS

Dutalfa Combipack Substitute

Substitutes safety advice
  • Alfusin D Tablet 15's

    by Others

    39.42per tablet
  • Afdura Tablet 10's

    by Others

    32.40per tablet
  • Flotral D Tablet 10's

    by AYUR

    32.40per tablet
  • Alfoo-D 0.5/10 Combipack Capsule 20's

    by Others

    17.73per tablet
  • Alfugress-D Tablet 10's

    by Others

    22.05per tablet
bannner image

Alcohol

Unsafe

Dutalfa Combipack should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

bannner image

Pregnancy

Unsafe

As the data on the use of Dutalfa Combipack in pregnant women is limited, the use of Dutalfa Combipack in pregnancy is restricted. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

bannner image

Breast Feeding

Unsafe

As the data on the use of Dutalfa Combipack in breastfeeding women is limited, the use of Dutalfa Combipack is restricted. It is highly recommended to consult your doctor before taking this drug in case you are breastfeeding.

bannner image

Driving

Caution

Dutalfa Combipack can make some people feel dizzy, which may affect your ability to drive or operate machinery safely.

bannner image

Liver

Caution

Dutalfa Combipack should not be taken until prescribed. Regular monitoring of liver function tests is recommended.

bannner image

Kidney

Caution

Dutalfa Combipack should not be taken until prescribed. Regular monitoring of kidney function tests is recommended.

bannner image

Children

Unsafe

Dutalfa Combipack is not recommended for children. The safety and effectiveness of Dutalfa Combipack have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

FAQs

Dutalfa Combipack is used to treat benign prostatic hyperplasia/enlarged prostate gland.
Dutalfa Combipack contains Alfuzosin (alpha-blockers) and dutasteride (5-alpha reductase inhibitor). Dutasteride lowers the production of dihydrotestosterone hormone, which leads to a decrease in the size of the prostate and, as a result, relieves the symptoms. Alfuzosin makes it easy to pass urine by relaxing the muscles of the gland. Both of them collectively improve Benign Hyperplasia Prostate symptoms (BPH).
You are advised not to take any cold or cough medication along with Dutalfa Combipack as it increases the urge to urinate. So, before taking any such medication, please consult your doctor.
Dutalfa Combipack does not cure urinary bladder cancer and should not be used for it. It helps in relieving symptoms of the enlarged prostate gland. For better advice, you should consult your doctor.
You are advised not to donate blood if you are taking Dutalfa Combipack as it contains Dutasteride, which is carried in the blood and can cause congenital disabilities. Even if you stop taking Dutalfa Combipack, wait for at least six months and consult your doctor before donating blood.
Yes, in some cases, sexual problems (like decreased sexual interest/ability/libido, ejaculation problems, decreased sperm/semen amount), testes pain/swelling, increased breast size, or breast tenderness in the male might occur. Sexual problems in a male may continue even after stopping the intake of Dutalfa Combipack. However, if these side effects persist, tell your doctor promptly.
No, it would be preferable to not restrict your water consumption to alleviate frequent urination. In fact, not drinking enough fluids can result in additional trips to the restroom. Dehydration can result in concentrated urine, which can irritate the bladder and raise the risk of urinary tract infections.
Yes, Dutalfa Combipack can be safe for elderly patients, but you should consult your doctor before taking it.
No, Dutalfa Combipack does not shrink the prostate.
No, Dutalfa Combipack does not cause erectile dysfunction. However, this combination of drugs can cause other sexual problems, such as Decreased sexual interest or libido, Ejaculation problems, and Decreased sperm or semen amount.
Yes, you can take Dutalfa Combipack at any time of day. However, it is generally recommended that you take it at the same time every day to improve medication adherence.
Yes, Dutalfa Combipack can affect the liver in rare cases. Therefore, it is recommended that liver function tests be regularly monitored.
Yes, Dutalfa Combipack can affect your eyes, and you should inform your doctor before having any eye surgery. In rare cases, Dutalfa Combipack may cause abnormal vision.
Yes, taking sildenafil or vardenafil with Dutalfa Combipack can cause serious problems, including a significant drop in blood pressure.
Dutalfa Combipack contains Alfuzosin and Dutasteride.
As the data on the use of Dutalfa Combipack in pregnant women is limited, the use of Dutalfa Combipack in pregnancy is restricted. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - DUT0005

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button