apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:51 AM IST

Duphaston Pro Tablet is used in the treatment of disorders like dysmenorrhea, endometriosis, infertility, irregular menstrual cycles, and premenstrual syndrome that are linked to progesterone deficiency. It can be used in conjunction with estrogen for hormone replacement therapy or in the treatment of dysfunctional bleeding or secondary amenorrhea. It contains Dydrogesterone, which is a female hormone that controls women's ovulation and menstruation. It causes secretive changes in the uterus's endometrium lining, promotes the breast's development, relaxes the uterus, blocks the maturation and release of the follicle, and retains pregnancy. It may cause side effects such as breast tenderness, swelling in other parts of the body, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding.

Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Abbott India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Duphaston Pro Tablet

Duphaston Pro Tablet is used in the treatment of disorders like dysmenorrhea, endometriosis, infertility, irregular menstrual cycles, and premenstrual syndrome that are linked to progesterone deficiency. Duphaston Pro Tablet can be used in conjunction with estrogen for hormone replacement therapy or in the treatment of dysfunctional bleeding or secondary amenorrhea. Infertility is the inability to conceive within 12 months. On the other hand, Premenstrual syndrome comprises signs and symptoms like mood swings, tender breasts, food cravings, fatigue, irritability, and depression. It occurs during certain days of the menstrual period in females, generally just before their menses.

Duphaston Pro Tablet is a female hormone that controls women's ovulation and menstruation. Duphaston Pro Tablet causes secretive changes in the uterus's endometrium lining, promotes the breast's development, relaxes the uterus, blocks the maturation and release of the follicle, and retains pregnancy.

Your doctor will advise you on your dose and how often you need to take this medication based on your medical condition. While using this medicine, you may sometimes have breast tenderness, swelling in other parts of the body, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding. Most of these side effects of Duphaston Pro Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Using Duphaston Pro Tablet may increase the risk of blood clots. Make sure that before taking this medicine, you inform your doctor if you have had breast cancer, unusual bleeding in the vagina, liver disease, or any other health problems. If you are taking any other medicine or are allergic to any medication, please inform your doctor. Avoid smoking and alcohol to prevent any unpleasant side effects. Duphaston Pro Tablet should not be used if you have heart disease or dementia because this medicine may increase your risk of developing these conditions.

Uses of Duphaston Pro Tablet

Treatment of Infertility, Prevention of miscarriages, Dysfunctional uterine bleeding, Irregular menses cycle, Dysmenorrhoea (painful periods), Endometriosis (A disorder in which tissue that normally lines the uterus grows outside the uterus), Treatment of threatened and habitual abortion associated with proven progesterone deficiency.

Medicinal Benefits

Duphaston Pro Tablet is a female hormone that regulates ovulation and menstruation in women. It helps maintain a healthy womb lining during the pregnancy stage. Duphaston Pro Tablet helps initiate the menses cycle (periods) in women who have not yet reached menopause. Besides this, it prevents overgrowth of the uterus in postmenopausal women who take estrogen as hormone replacement therapy (HRT). Duphaston Pro Tablet is used to regulate the uterine lining in postmenopausal women receiving estrogens who have not removed their uterus through surgery. It also helps treat amenorrhea (cessation or irregular menses cycle for more than three months). It is also given in combination with estrogens as part of menopausal replacement therapy. The injection form of Duphaston Pro Tablet is prescribed for treating abnormal uterine bleeding along with irregular or ceased menstrual cycles. The intravaginal gel form of Duphaston Pro Tablet assists in reproductive technology for infertile women with progesterone deficiency or irregular or ceased menstrual cycle. The vaginal insert form of Duphaston Pro Tablet supports early pregnancy and implantation of an embryo in the uterus. Off-label use of Duphaston Pro Tablet helps in reducing the risk of preterm birth.

Directions for Use

Duphaston Pro Tablet should be swallowed as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Duphaston Pro Tablet

  • Abdominal pain
  • Bloating
  • Headache
  • Dizziness
  • Depression
  • Breast tenderness
  • Hot flushes
  • Vaginal discharge
  • Joint pain
  • Urinary problems
  • Nausea
  • Fatigue or extreme tiredness
  • Somnolence or sleepiness
  • Vaginal haemorrhage
  • Pruritus (severe itching of the skin)

Drug Warnings

Duphaston Pro Tablet with estrogens should not be used to prevent heart disease, heart attacks, strokes, or dementia. Using Duphaston Pro Tablet with estrogens may increase the chance of getting heart attacks, strokes, breast cancer, and blood clots. In some cases, using Duphaston Pro Tablet with estrogen may produce dementia among women aged 65 and older. Do not use Duphaston Pro Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or undergoing estrogen plus progestin treatment. Tell your doctor before using the Duphaston Pro Tablet if you have had a heart attack, stroke, blood clot, liver problems, kidney problems, pregnant, breastfeeding or planning to get pregnant, asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, heart problems, thyroid, or have high calcium levels in your blood. Use caution while driving a motor vehicle, as dizziness or drowsiness may occur. If you are using Duphaston Pro Tablet before any lab tests or biopsies, tell your doctor about this, as it can affect the report values. Patients with rare hereditary problems like galactose intolerance, lactase deficiency or glucose-galactose malabsorption should not take the Duphaston Pro Tablet.

Drug Interactions

Drug-Drug Interactions: This medicine may interact with medications, including anticonvulsants (e.g. acetazolamide, carbamazepine), anti-infectives (e.g. metronidazole, clindamycin), and certain herbal preparations (e.g. Ginkgo Biloba).

Drug-Food Interactions: Duphaston Pro Tablet may interact with grapefruit or grapefruit juice and St. John’s wort plant (used for anti-depression). 

Drug-Disease Interactions: Duphaston Pro Tablet may interact with disease conditions, including breast cancer, liver disease, thromboembolism, depression, fluid retention (oedema), glucose intolerance, retinal thrombosis (blocked vein of the retina of the eye), thyroid disease, high cholesterol (hyperlipidemia), uterine bleeding, ovarian cyst, and weight gain (obesity).

Drug-Drug Interactions Checker List

  • ACETAZOLAMIDE
  • CARBAMAZEPINE
  • METRONIDAZOLE
  • CLINDAMYCIN
  • GINKGO BILOBA EXTRACT

Habit Forming

No

Diet & Lifestyle Advise

  • Regular exercise and physical activity can minimize hot flushes and improve sleep. Weight-bearing exercises can also help strengthen bones. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take a minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Disease/Condition Glossary

Female Infertility: When a woman is not able to become pregnant within a year of trying. If a woman gets pregnant but experiences miscarriages or stillbirths, it is classified under infertility.

Hormone replacement therapy (HRT): It is a treatment to relieve the symptoms of menopause. It replaces hormones that are at a lower level as you approach menopause.

Premenstrual syndrome (PMS): PMS (premenstrual syndrome) is the name for the symptoms women can experience in the weeks before their menstrual period. Each woman's symptoms are different and can vary from month to month. The most common symptoms of PMS include mood swings, feeling upset, anxious, or irritable, tiredness, breast tenderness, headaches, etc.

bannner image

Alcohol

Caution

You are recommended not to consume alcohol along with Duphaston Pro Tablet to avoid unpleasant side effects.

bannner image

Pregnancy

Safe if prescribed

Duphaston Pro Tablet can be safely used in pregnant women. Your doctor will weigh the benefits and potential risks before prescribing them. If you have any concerns regarding this, discuss them with the doctor.

bannner image

Breast Feeding

Caution

Duphaston Pro Tablet should be used in breastfeeding mothers only if the benefits outweigh the risks. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

bannner image

Driving

Caution

It is advised to drive with caution after taking Duphaston Pro Tablet as it may interfere with driving capabilities. It can make you feel drowsy.

bannner image

Liver

Caution

Limited information was available for the use of Duphaston Pro Tablet in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using Duphaston Pro Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Limited information was available for the use of Duphaston Pro Tablet in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using Duphaston Pro Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

Duphaston Pro Tablet is not recommended for children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot ? C, ?G? Block, Bandra-Kurla Complex, Bandra (East), Mumbai ? 400 051, India.
Other Info - DUP0052

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Duphaston Pro Tablet is used in the treatment of infertility, prevention of miscarriages, dysfunctional uterine bleeding, irregular menses cycle, dysmenorrhoea (painful periods), endometriosis (a disorder in which tissue that normally lines the uterus grows outside the uterus), threatened and habitual abortion associated with proven progesterone deficiency.
Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy, and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high levels of estrogen, and women can have decreased sex drive (libido), weight gain, or gallbladder problems.
Yes, Duphaston Pro Tablet might cause ovarian cysts. These are small fluid-filled sacs that can occur on ovaries. These are harmless. They disappear without treatment.
Duphaston Pro Tablet helps in preparing the endometrium potential for pregnancy after ovulation. It thickens the lining of the endometrium to accept a fertilized egg. It also prevents muscle contractions of the uterus that would reject an egg in the uterus. So, if the body has a high progesterone level, ovulation will not occur then.
Yes, Duphaston Pro Tablet may cause weight gain. It can be due to water retention. If you feel that you are gaining a lot of weight while taking Duphaston Pro Tablet, please consult your doctor.
Yes, Duphaston Pro Tablet can be taken every day. This medicine is prescribed once daily, preferably in the evening or at bedtime. Please take it in the dose and duration as advised by the doctor.
Yes, Duphaston Pro Tablet is used to prevent habitual miscarriage and regular abortion. Your doctor will decide whether you should continue or stop taking Duphaston Pro Tablet. Do not take medication of your own or self-medicate.
Yes, Duphaston Pro Tablet is synthetic or man-made progesterone, which is very similar to progesterone made by your body. It is taken in various gynaecological problems when your body is unable to make a sufficient amount of natural progesterone.
The most common side effects of Duphaston Pro Tablet are migraines/headaches, nausea, menstrual disorders and breast pain/tenderness.
There is no clinical evidence that Duphaston Pro Tablet decreases fertility at therapeutic doses. However, taking it only after consulting any obstetrician/gynaecologist is better.
Duphaston Pro Tablet should be taken for the duration prescribed by the doctor. The dose and duration will depend upon your condition and response to treatment. Talk to your doctor if you have any concerns.
In some cases, Duphaston Pro Tablet may increase the risk of birth defects such as hypospadias (the opening of the urethra is not located at the tip of the penis) and congenital heart defects.
Dydrogesterone is a synthetic form of progesterone. Dydrogesterone is used in conditions when the body does not make enough progesterone.
Do not take Duphaston Pro Tablet if you are allergic to any of its components, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or are undergoing oestrogen plus progestin treatment.
If you forget a dose, take the missed dose as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose.
Duphaston Pro Tablet may cause breast pain and tenderness as a side effect. Consult the doctor if the condition persists or worsens or if you notice any other changes in your breast such as a lump.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.