Duphaston 5 mg Tablet is used in the treatment of disorders like dysmenorrhea, endometriosis, infertility, irregular menstrual cycles, and premenstrual syndrome that are linked to progesterone deficiency. Duphaston 5 mg Tablet can be used in conjunction with estrogen for hormone replacement therapy or in the treatment of dysfunctional bleeding or secondary amenorrhea. Infertility is the inability to conceive within 12 months. On the other hand, Premenstrual syndrome comprises signs and symptoms like mood swings, tender breasts, food cravings, fatigue, irritability, and depression. It occurs during certain days of the menstrual period in females, generally just before their menses.

Duphaston 5 mg Tablet is a female hormone that controls women's ovulation and menstruation. Duphaston 5 mg Tablet causes secretive changes in the uterus's endometrium lining, promotes the breast's development, relaxes the uterus, blocks the maturation and release of the follicle, and retains pregnancy.

Your doctor will advise you on your dose and how often you need to take this medication based on your medical condition. While using this medicine, you may sometimes have breast tenderness, swelling in other parts of the body, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding. Most of these side effects of Duphaston 5 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Using Duphaston 5 mg Tablet may increase the risk of blood clots. Make sure that before taking this medicine, you inform your doctor if you have had breast cancer, unusual bleeding in the vagina, liver disease, or any other health problems. If you are taking any other medicine or are allergic to any medication, please inform your doctor. Avoid smoking and alcohol to prevent any unpleasant side effects. Duphaston 5 mg Tablet should not be used if you have heart disease or dementia because this medicine may increase your risk of developing these conditions.

Duphaston 5 mg Tablet is a female hormone that regulates ovulation and menstruation in women. It helps maintain a healthy womb lining during the pregnancy stage. Duphaston 5 mg Tablet helps initiate the menses cycle (periods) in women who have not yet reached menopause. Besides this, it prevents overgrowth of the uterus in postmenopausal women who take estrogen as hormone replacement therapy (HRT). Duphaston 5 mg Tablet is used to regulate the uterine lining in postmenopausal women receiving estrogens who have not removed their uterus through surgery. It also helps treat amenorrhea (cessation or irregular menses cycle for more than three months). It is also given in combination with estrogens as part of menopausal replacement therapy. The injection form of Duphaston 5 mg Tablet is prescribed for treating abnormal uterine bleeding along with irregular or ceased menstrual cycles. The intravaginal gel form of Duphaston 5 mg Tablet assists in reproductive technology for infertile women with progesterone deficiency or irregular or ceased menstrual cycle. The vaginal insert form of Duphaston 5 mg Tablet supports early pregnancy and implantation of an embryo in the uterus. Off-label use of Duphaston 5 mg Tablet helps in reducing the risk of preterm birth.

• Abdominal pain
• Bloating
• Headache
• Dizziness
• Depression
• Breast tenderness
• Hot flushes
• Vaginal discharge
• Joint pain
• Urinary problems
• Nausea
• Fatigue or extreme tiredness
• Somnolence or sleepiness
• Vaginal haemorrhage
• Pruritus (severe itching of the skin)

Duphaston 5 mg Tablet with estrogens should not be used to prevent heart disease, heart attacks, strokes, or dementia. Using Duphaston 5 mg Tablet with estrogens may increase the chance of getting heart attacks, strokes, breast cancer, and blood clots. In some cases, using Duphaston 5 mg Tablet with estrogen may produce dementia among women aged 65 and older. Do not use Duphaston 5 mg Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or undergoing estrogen plus progestin treatment. Tell your doctor before using the Duphaston 5 mg Tablet if you have had a heart attack, stroke, blood clot, liver problems, kidney problems, pregnant, breastfeeding or planning to get pregnant, asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, heart problems, thyroid, or have high calcium levels in your blood. Use caution while driving a motor vehicle, as dizziness or drowsiness may occur. If you are using Duphaston 5 mg Tablet before any lab tests or biopsies, tell your doctor about this, as it can affect the report values. Patients with rare hereditary problems like galactose intolerance, lactase deficiency or glucose-galactose malabsorption should not take the Duphaston 5 mg Tablet .

Drug-Drug Interactions: This medicine may interact with medications, including anticonvulsants (e.g. acetazolamide, carbamazepine), anti-infectives (e.g. metronidazole, clindamycin), and certain herbal preparations (e.g. Ginkgo Biloba).

Drug-Food Interactions: Duphaston 5 mg Tablet may interact with grapefruit or grapefruit juice and St. John’s wort plant (used for anti-depression). 

Drug-Disease Interactions: Duphaston 5 mg Tablet may interact with disease conditions, including breast cancer, liver disease, thromboembolism, depression, fluid retention (oedema), glucose intolerance, retinal thrombosis (blocked vein of the retina of the eye), thyroid disease, high cholesterol (hyperlipidemia), uterine bleeding, ovarian cyst, and weight gain (obesity).

• ACETAZOLAMIDE
• CARBAMAZEPINE
• METRONIDAZOLE
• CLINDAMYCIN
• GINKGO BILOBA EXTRACT

• Regular exercise and physical activity can minimize hot flushes and improve sleep. Weight-bearing exercises can also help strengthen bones. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
• Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take a minimum sleep of 8 hours. 
• Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
• Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
• Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Female Infertility: When a woman is not able to become pregnant within a year of trying. If a woman gets pregnant but experiences miscarriages or stillbirths, it is classified under infertility.

Hormone replacement therapy (HRT): It is a treatment to relieve the symptoms of menopause. It replaces hormones that are at a lower level as you approach menopause.

Premenstrual syndrome (PMS): PMS (premenstrual syndrome) is the name for the symptoms women can experience in the weeks before their menstrual period. Each woman's symptoms are different and can vary from month to month. The most common symptoms of PMS include mood swings, feeling upset, anxious, or irritable, tiredness, breast tenderness, headaches, etc.