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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 26, 2024 | 7:08 PM IST
Duobrim-T Eye Drop 5 ml is used to treat open-angle glaucoma and (ocular hypertension) high pressure in the eyes. It contains Brimonidine and Timolol. It acts by narrowing the blood vessels that reduce the flow of aqueous humour. Also, it decreases the secretion of aqueous humour by acting on ciliary body in the eye, thereby causing a decrease in the eye pressure. It may cause some common side effects such as itching, stinging sensation, foreign body sensation in the eye, burning sensation in eye, redness, blurred vision, tiredness, drowsiness, headache, and dryness in the mouth. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Senses Pharmaceuticals Pvt Ltd

Consume Type

OPHTHALMIC

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Duobrim-T Eye Drop 5 ml

Duobrim-T Eye Drop 5 ml is used to treat open-angle glaucoma and ocular hypertension (high pressure in the eyes). Glaucoma is a common eye condition where the optic nerve, which connects the eye to the brain, becomes damaged. It's usually caused by fluid building up in the front part of the eye, which increases pressure inside the eye. 

Duobrim-T Eye Drop 5 ml is a combination of two medicines, namely Brimonidine and Timolol. Brimonidine is a sympathomimetic drug, an agent that mimics the responses of sympathetic nerves. It acts by narrowing the blood vessels that reduce the flow of aqueous humour. Timolol belongs to a class of anti-hypertensive drugs called 'beta-blockers' primarily used to treat increased pressure in the eye. It decreases the secretion of aqueous humour by acting on a ciliary body in the eye, thereby causing a decrease in eye pressure.

Your doctor will advise on how often you take Duobrim-T Eye Drop 5 ml based on your medical condition. Some common side effects of Duobrim-T Eye Drop 5 ml include itching, stinging sensation, foreign body sensation in the eye, burning sensation in the eye, redness, blurred vision, tiredness, drowsiness, headache, and dryness in the mouth. These side effects do not require medical attention and gradually resolve over time. Although not all of these side effects may occur, they may need medical attention if they do occur.

Try not to stop taking this medicine of your own. You should not use Duobrim-T Eye Drop 5 ml without consulting your doctor if you have an eye infection, allergies, closed-angle glaucoma, thyroid diseases, asthma, chronic obstructive pulmonary disease (COPD), heart, liver and kidney diseases, diabetes, high or low blood pressure, depression, Raynaud's phenomenon (numbness in various parts of the body), and slow heartbeats that make you faint. It is not recommended to use Duobrim-T Eye Drop 5 ml during breastfeeding since Timolol can pass into breast milk. Check with your doctor before using Duobrim-T Eye Drop 5 ml if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines.

Uses of Duobrim-T Eye Drop 5 ml

Treatment of Open-angle glaucoma and Ocular hypertension.

Medicinal Benefits

Duobrim-T Eye Drop 5 ml effectively treats open-angle glaucoma and (ocular hypertension) high pressure in the eyes. Duobrim-T Eye Drop 5 ml consists of Brimonidine and Timolol. Brimonidine is a sympathomimetic drug, an agent which mimics the responses of sympathetic nerves. It acts by narrowing the blood vessels that reduce the flow of aqueous humour. Timolol belongs to a class of anti-hypertensive drugs called 'beta-blockers' primarily used to treat increased pressure in the eye. It decreases the secretion of aqueous humour by the ciliary body in the eye, thereby causing a decrease in eye pressure. 

Directions for Use

Eye drops: Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Duobrim-T Eye Drop 5 ml

  • Itching
  • Stinging sensation
  • Foreign body sensation
  • Burning sensation in the eye
  • Redness
  • Blurred vision
  • Tiredness
  • Drowsiness
  • Headache
  • Dryness in the mouth.

Drug Warnings

Before taking Duobrim-T Eye Drop 5 ml, let your doctor know if have a history of eye infection, allergies, closed-angle glaucoma, thyroid diseases, asthma, chronic obstructive pulmonary disease (COPD), heart, liver and kidney diseases, diabetes, high or low blood pressure, depression, Raynaud's phenomenon (numbness in various parts of the body), and slow heartbeats that make you faint. Please consult your doctor if you are pregnant, planning to conceive or are a breastfeeding mother. Duobrim-T Eye Drop 5 ml can cause blurry vision; hence drive or operate machinery only if you are able to see things clearly. It is better to avoid alcohol while being treated with Duobrim-T Eye Drop 5 ml

Drug Interactions

Drug-Drug Interaction: Duobrim-T Eye Drop 5 ml may interact with respiratory drugs (fluticasone, salmeterol), fluid retention medicine (furosemide), fits medication (pregabalin), anxiety medicine (alprazolam), blood pressure drugs (clonidine), anti-depressants (fluoxetine, paroxetine), anti-psychotics (isocarboxazid, selegiline), and anti-diabetics. 

Drug-Food Interaction: The absorption of Duobrim-T Eye Drop 5 ml can cause dizziness, drowsiness, and difficulty concentrating. In such cases, consumption of alcohol increases the risk. Hence avoid or limit the intake of alcohol.

Drug-Disease Interaction: Brief your doctor if you have a medical history of closed-angle glaucoma, thyroid diseases, asthma, chronic obstructive pulmonary disease, heart, liver and kidney diseases, diabetes, high or low blood pressure, depression, and Raynaud's phenomenon before taking Duobrim-T Eye Drop 5 ml.

Drug-Drug Interactions Checker List

  • FLUTICASONE
  • SALMETEROL
  • FUROSEMIDE
  • PREGABALIN
  • ALPRAZOLAM
  • CLONIDINE
  • FLUOXETINE
  • PAROXETINE
  • ISOCARBOXAZID
  • SELEGILINE

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands regularly. Avoid touching the eyes with dirty hands. 

  • Avoid rubbing the eyes.

  • Avoid sharing eye makeup, such as eyeliner, mascara or kohl.

  • Always use clean towels or tissues to wipe your eyes and face.

  • Try to maintain good hygiene to keep your eyes clean and irritant-free.

  • If you wear contact lenses, clean and replace contact lenses more often. Never share contact lenses. Always remember to wash your hands before using and removing the contact lens. 

  • Avoid staring at the digital screens for longer durations. Rest your eyes every 20 minutes.

Disease/Condition Glossary

Glaucoma is a common eye condition where the optic nerve, which connects the eye to the brain, becomes damaged. It's usually caused by fluid building up in the front part of the eye, which increases pressure inside the eye.  Glaucoma can lead to loss of vision if it's not diagnosed and treated early.

Open-angle glaucoma is a life-long condition and the most common type of glaucoma. It is caused by the clogging of the drainage angle between the iris and cornea, which leads to the blockage of eye fluid and increases eye pressure.

Ocular hypertension is the build-up of pressure in the eye, caused by poor drainage of the aqueous humour (fluid inside the eye that maintains normal pressure).

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Alcohol

Caution

Interaction of alcohol with Duobrim-T Eye Drop 5 ml is unknown. Please consult a doctor before consuming alcohol with Duobrim-T Eye Drop 5 ml.

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Pregnancy

Caution

Please consult your doctor if you are planning to become pregnant or already pregnant before starting Duobrim-T Eye Drop 5 ml.

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Breast Feeding

Caution

It is not recommended to use Duobrim-T Eye Drop 5 ml during breastfeeding since Timolol can pass into breast milk and harm a nursing baby. Consult your doctor before starting Duobrim-T Eye Drop 5 ml.

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Driving

Caution

Duobrim-T Eye Drop 5 ml may cause side effects like blurry vision which could affect your ability to drive. Do not drive or operate machinery in such cases. Drive only when you are alert and have a clear vision.

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Liver

Caution

Let your doctor know if you have any history of liver diseases. Your doctor will weigh the benefits and potential risks before prescribing Duobrim-T Eye Drop 5 ml.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Duobrim-T Eye Drop 5 ml.

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Children

Caution

The dose may have to be adjusted by your doctor depending upon the condition of the children's disease and age.

Country of origin

India

Manufacturer/Marketer address

New No:4, (Old No:15/4), Hemanth Plaza, 80 Feet Main Road, 2Nd Stage, Padmanabhanagar, Benguluru - 560070.
Other Info - DUO0210

FAQs

Duobrim-T Eye Drop 5 ml is used to treat open-angle glaucoma and ocular hypertension (high pressure in the eyes).
Duobrim-T Eye Drop 5 ml consists of Brimonidine and Timolol. Brimonidine acts by narrowing the blood vessels that reduce the flow of aqueous humour. Timolol decreases the secretion of aqueous humour by the ciliary body in the eye, thereby causing a decrease in eye pressure. Thus Duobrim-T Eye Drop 5 ml treats open-angle glaucoma and ocular hypertension.
If you use other eye ointments/drops along with Duobrim-T Eye Drop 5 ml, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any ointments.
Duobrim-T Eye Drop 5 ml may cause a blurry vision for some time in the beginning. Avoid driving and operating machinery in such cases until you feel better. If the effect persists longer, seek medical attention.
Apply the drops as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
Do not discontinue Duobrim-T Eye Drop 5 ml without consulting your doctor. To treat your condition effectively, keep taking Duobrim-T Eye Drop 5 ml for the prescribed duration.
Store Duobrim-T Eye Drop 5 ml at room temperature, in a dry place. Do not freeze and protect from light. Keep out of sight and reach of children.
Duobrim-T Eye Drop 5 ml is contraindicated in people who are allergic to any of its components, in people with asthma, severe chronic obstructive bronchitis, heart problems (low heart rate, heart failure, heartbeat disorders), and in people taking monoamine oxidase (MAO) inhibitors or certain other antidepressant drugs.
Side effects of Duobrim-T Eye Drop 5 ml include itching, stinging sensation, foreign body sensation in the eye, burning sensation in the eye, redness, blurred vision, tiredness, drowsiness, headache, and dryness in the mouth. Consult the doctor if the side effects persist or worsen.

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