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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 10:52 AM IST

Duobloc Tablet is used to treat Pain associated with musculoskeletal disorders. It contains Phenyramidol, which belongs to the muscle relaxant class. It works by inhibiting the polysynaptic reflexes in the brain and spinal cord, inhibiting the transmission of pain signals from nerves to the brain. This provides relief from muscle stiffness or muscle spasms and improves muscle strength.

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Prescription drug

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Prescription drug
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Synonym

FENYRAMIDOL

Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Duobloc Tablet

Duobloc Tablet is a muscle relaxant used in relieving pain. Pain can be acute (temporary) or chronic (long-lasting). Acute pain is a short-term pain caused by damage to the tissues of the muscle, bone, or other organs. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage, etc. Duobloc Tablet helps provide relief from musculoskeletal pain, integumental pain (Pain occurring in the integumentary system) and lumbago pain (pain in the lower back muscles and nerves).

Duobloc Tablet contains Phenyramidol, which belongs to the class of muscle relaxants. It works by inhibiting the polysynaptic reflexes in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. This provides relief from muscle stiffness or muscle spasms and improves muscle strength.

Duobloc Tablet may cause certain side effects like nausea, dizziness, headache, vomiting, dry mouth, drowsiness, constipation, sweating, or tiredness. Most of these side effects of Duobloc Tablet do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor. Duobloc Tablet should be taken as advised by your doctor. Do not take more than the prescribed dose of Duobloc Tablet . Duobloc Tablet should be taken with food. Your doctor will decide the dose of the medicine depending on the type and severity of the condition.

Duobloc Tablet should be avoided if you are allergic to it. To rule out any interactions, keep your doctor informed about your health condition and medicines. This medicine should be used under caution in patients with liver/kidney disease. Duobloc Tablet may cause drowsiness and dizziness, so drive with caution. Avoid consuming alcohol with Duobloc Tablet as it could cause increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. It is advised not to take more than the prescribed dose of medicine and for a longer period. If you are pregnant, planning for a pregnancy or are breastfeeding, inform your doctor before taking Duobloc Tablet .  

Uses of Duobloc Tablet

Treatment of Pain associated with musculoskeletal disorders

Medicinal Benefits

Duobloc Tablet contains Phenyramidol, which belongs to the class of muscle relaxants. It works by inhibiting the polysynaptic reflexes in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. This provides relief from muscle stiffness or muscle spasms and improves muscle strength.

Directions for Use

Duobloc Tablet should be taken as advised by your doctor. Swallow it as a whole with a glass of water. Do not chew break or crush the medicine. It is advised not to take more than the prescribed dose of medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Duobloc Tablet

  • Nausea
  • Diarrhoea
  • Stomach upset
  • Indigestion
  • Dizziness
  • Drowsiness
  • Dry mouth

Drug Warnings

Duobloc Tablet should be avoided if you are allergic to it. To rule out interactions, inform your doctor about your health condition and medicines. This medicine should be used under caution in patients with liver/kidney disease. Duobloc Tablet may cause drowsiness and dizziness, so drive with caution. Duobloc Tablet is not recommended for children below 16 years of age as safety and efficacy have not been established. Avoid consuming alcohol with Duobloc Tablet as it could cause increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. It is advised not to take more than the prescribed dose of medicine and for a longer period. If you are pregnant, planning for a pregnancy or are breastfeeding, inform your doctor before taking Duobloc Tablet .  

Drug Interactions

Drug-Drug Interaction: Duobloc Tablet may have interaction with pain killers (pentazocine, buprenorphine, nalbuphine), blood thinners (warfarin), anti-anxiety drugs (alprazolam), fits related medicines (carbamazepine), medicines used to prevent nausea (ondansetron), antifungal drugs (ketoconazole), antibiotic (ciprofloxacin, erythromycin), anticancer drugs (ceritinib, lapatinib), immunosuppressants (fingolimod), antidepressants (fluoxetine, doxepin), antipsychotics (droperidol), and HIV/AIDS drugs (saquinavir).

Drug-Food Interaction: Duobloc Tablet may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Duobloc Tablet as it may increase Duobloc Tablet levels in the body. Also, avoid alcohol consumption while taking Duobloc Tablet as it may increase the risk of adverse effects such as drowsiness, dizziness and difficulty in concentrating.

Drug-Disease Interaction: People with severe kidney or liver problems, fits, and breathing problems should consult a doctor before taking Duobloc Tablet .

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • ONDANSETRON
  • KETOCONAZOLE
  • ERYTHROMYCIN
  • CIPROFLOXACIN
  • FLUOXETINE
  • DOXEPIN
  • WARFARIN
  • ALPRAZOLAM

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.

Disease/Condition Glossary

Pain: Pain can be short-term (acute) or long-term (chronic). Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. In contrast, chronic pain lasts for a longer duration. It is caused by pathologies like nerve damage, Osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Duobloc Tablet is used to relieve mild to moderate musculoskeletal disorders, integumental pain, and lumbago pain.

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Alcohol

Unsafe

Avoid consumption of alcohol with Duobloc Tablet as it may cause drowsiness or increase the risk of side effects.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before taking Duobloc Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before taking Duobloc Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Duobloc Tablet may cause dizziness or drowsiness in some people. Hence, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Duobloc Tablet .

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Duobloc Tablet .

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment before taking Duobloc Tablet .

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Children

Consult your doctor

It is unknown whether Duobloc Tablet can be given to children or not. Hence, it should be given to children only if prescribed by the paediatrician.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - DUO0119

FAQs

Duobloc Tablet is used to treat Pain associated with musculoskeletal disorders.
Duobloc Tablet contains Phenyramidol, which works by inhibiting the action of pain-reducing chemicals in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain.
Avoid exceeding the dose and duration advised by the doctor. Taking more than the daily dose of Duobloc Tablet might cause serious liver damage or allergic reactions like rash, difficulty breathing, and swelling of the face, throat, and mouth. Therefore, Duobloc Tablet should not be taken for longer durations unless prescribed by the doctor.

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