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Written By , M Pharmacy
Reviewed By , M Pharmacy
Last Updated Jan 1, 2025 | 2:45 PM IST
Doxific Plus Injection is an antibiotic medicine used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections, and periodontitis. This medicine contains doxycycline which works by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections. Common side effects include pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea.
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Prescription drug

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Composition :

DOXYCYCLINE-100MG

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Doxific Plus Injection

Doxific Plus Injection belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Doxific Plus Injection may also be used to treat or prevent anthrax.

Doxific Plus Injection contains 'Doxycycline' which stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxific Plus Injection helps treat bacterial infections. It is a broad-spectrum antibiotic which is effective against both gram-negative and gram-positive bacteria.

Doxific Plus Injection will be administered by a healthcare professional; do not self-administer. In some cases, Doxific Plus Injection may cause pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea. Most of these side effects of Doxific Plus Injection do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Do not take Doxific Plus Injection if you are allergic to any of the components. Consult your doctor if you are pregnant or breastfeeding. Use of Doxific Plus Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Doxific Plus Injection

Treatment of Bacterial infections

Medicinal Benefits

Doxific Plus Injection belongs to the class of medicines called tetracycline antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites. It is used to treat respiratory tract infections (influenza, pneumonia), genitourinary infections (syphilis, gonorrhoea), anthrax infection, sinuses, eye, and skin infections. Besides this, it is also indicated in the tick-borne infections (typhus fever) caused by the Rickettsia group of bacteria like typhus fever. Off-label, usage includes the prevention of malaria and the treatment of acne.

Side Effects of Doxific Plus Injection

  • Pain, itching, swelling or redness at the site of injection
  • Nausea
  • Vomiting
  • Diarrhoea

Directions for Use

Doxific Plus Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Doxific Plus Injection if you are allergic to any of its contents. Inform your doctor if you have lupus, or if you are pregnant or breastfeeding.  Use of Doxific Plus Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Consult your doctor if you experience any skin reactions, fever,  muscle, or joint problems.

Therapeutic Class

ANTIBIOTICS

Drug-Drug Interactions

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DoxycyclineAcitretin
Critical
DoxycyclineEtretinate
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • It would be best to take probiotics after completing the full course of Doxific Plus Injection to restore healthy bacteria in the intestine that may have been killed due to the usage of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Doxific Plus Injection.
  • Avoid intake of alcoholic beverages with Doxific Plus Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Doxific Plus Injection in fighting off infections.

Habit Forming

No

How Doxific Plus Injection Works

Doxific Plus Injection contains 'Doxycycline' which stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxific Plus Injection helps treat bacterial infections. It is a broad-spectrum antibiotic which is effective against both gram-negative and gram-positive bacteria.

What if I have taken an overdose of Doxific Plus Injection

Doxific Plus Injection is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. Overdose can cause nausea, vomiting, diarrhea, photosensitivity (skin reaction to the sun), indigestion, loss of appetite and mild rash. Your doctor may initiate necessary treatment if an overdose is suspected.
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Alcohol

Caution

It is not known if alcohol affects Doxific Plus Injection. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Doxific Plus Injection belongs to pregnancy category D. There are no adequate and well-controlled studies on the use of Doxific Plus Injection in pregnant women. In some cases, taking Doxific Plus Injection during pregnancy may affect tooth and bone development in the unborn baby. So, if you are pregnant or planning for pregnancy contact the doctor before using Doxific Plus Injection.

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Breast Feeding

Caution

Doxific Plus Injection is excreted in the breast milk. However, the extent of absorption of Doxific Plus Injection by the breastfed infant is not known. Hence, the nursing mother should consult the doctor before using Doxific Plus Injection.

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Driving

Caution

It is not known if Doxific Plus Injection affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Doxific Plus Injection is to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

At the recommended doses, Doxific Plus Injection is safe to use in patients with kidney disease if prescribed by a doctor.

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Children

Caution

Use of Doxific Plus Injection during tooth development in infants and children below 8 years of age may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for children below 8 years of age.

Country of origin

INDIA

Manufacturer/Marketer address

37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)
Other Info - DOX0347

Author Details

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FAQs

Doxific Plus Injection belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Doxific Plus Injection may also be used to treat or prevent anthrax.
Doxific Plus Injection stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxific Plus Injection helps treat bacterial infections.
No, Doxific Plus Injection should not be stopped even if you feel better as it is an antibiotic medication and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form and will also become difficult to treat due to antibiotic resistance.
If you are taking Doxific Plus Injection, avoid taking antacids containing aluminium, calcium or magnesium or other drugs containing these cations; oral zinc, iron salts or bismuth preparations within 2 hours of consumption of Doxific Plus Injection as they may affect the absorption of Doxific Plus Injection. Avoid taking dairy products within 2 hours of taking Doxific Plus Injection as they may also impair the absorption of Doxific Plus Injection.
Use of Doxific Plus Injection during tooth development (last half of pregnancy, infancy, and in children below the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for pregnant women, breastfeeding mothers, and children below 8 years of age.
Doxific Plus Injection may make your skin sensitive to sunlight. So, apply sunscreen while going out and wear protective clothing and sunglasses. Avoid prolonged and unnecessary exposure to sunlight.
Doxific Plus Injection may lower the effectiveness of hormonal contraceptives such as birth control pills, rings, patches, or injections. Consult your doctor if you have any concerns, your doctor may advise regarding other forms of contraception.
Doxific Plus Injection does not completely prevent malaria caused by P. falciparum as Doxific Plus Injection is given as a prophylactic regimen (protection) whenever anyone enters a malaria-prone area.

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