Doxferol D2 Tablet 10's

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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Doxferol D2 Tablet contains Doxercalciferol, which belongs to the vitamin D analogue class of medications. It promotes the body's consumption of calcium from food or supplements and the management of parathyroid hormone synthesis. Thus, Doxercalciferol helps to treat secondary hyperparathyroidism in chronic renal disease patients. Common side effects of this medication are headache, dizziness, heartburn, sleep disorders, joint pain, and weight gain.

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About Doxferol D2 Tablet

Doxferol D2 Tablet is used to treat secondary hyperparathyroidism in chronic renal disease patients with or without dialysis therapy. Secondary hyperparathyroidism occurs when the parathyroid glands enlarge and produce an excessive amount of PTH, resulting in a high PTH level in the blood.

Doxferol D2 Tablet contains Doxercalciferol. It promotes the body's consumption of calcium from food or supplements, as well as the management of parathyroid hormone synthesis.

It's available on prescription; take it as directed by your physician. Sometimes, you may experience certain common side effects, including headache, dizziness, heartburn, sleep disorders, joint pain, and weight gain. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult a doctor.

Using Doxferol D2 Tablet is contraindicated in patients who have a history of hypercalcemia, have current evidence of vitamin D toxicity, or are allergic to any of its components. So, before taking Doxferol D2 Tablet , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Doxferol D2 Tablet should be used during pregnancy only if clearly needed, as there are no adequate and well-controlled studies in pregnant women. It is unknown whether Doxercalciferol is excreted in human milk. Considering the importance of the drug to the mother, a decision should be made whether to quit nursing or the medicine. So, inform your doctor if you are pregnant or suspect pregnancy or nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Doxferol D2 Tablet .

Uses of Doxferol D2 Tablet

Doxferol D2 Tablet is used in the treatment of Secondary Hyperparathyroidism. The detailed uses of Doxferol D2 Tablet are as follows:

Treatment of Secondary Hyperparathyroidism in CKD: Doxferol D2 Tablet is used to manage elevated parathyroid hormone (PTH) levels in patients with chronic kidney disease (CKD), including those undergoing dialysis, helping regulate calcium and phosphorus balance.
Vitamin D Analog Therapy: Doxferol D2 Tablet acts as a synthetic form of vitamin D2, enhancing calcium absorption from the gut and suppressing excess PTH production without significantly increasing calcium or phosphorus levels.
Support for Bone Health in Renal Patients: Doxferol D2 Tablet helps reduce the risk of bone disorders associated with CKD by improving mineral metabolism and preventing renal osteodystrophy.

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Directions for Use

Take Doxferol D2 Tablet with or without food or as advised by a doctor.
Follow your doctor’s instructions on the dosage and timing of this medication, to ensure the safety.
Swallow the medicine as a whole with a glass of water.
Do not crush, break, or chew it.

Medicinal Benefits

Doxferol D2 Tablet contains Doxercalciferol, which belongs to the vitamin D analogue class of medications. It promotes the body's consumption of calcium from food or supplements, as well as the management of parathyroid hormone synthesis. Thus, Doxercalciferol helps to treat secondary hyperparathyroidism in chronic renal disease patients.

How Doxferol D2 Tablet Works

Doxferol D2 Tablet contains Doxercalciferol. It promotes the body's consumption of calcium from food or supplements, as well as the management of parathyroid hormone synthesis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Doxferol D2 Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Side effects of Doxferol D2 Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Feeling Of Discomfort, Illness, Or Unease

Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:

If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention.
Inform your doctor about the medication you're taking and the symptoms you're experiencing.
Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Swelling

Reduce salt intake to minimize fluid buildup.
Use compression stockings, sleeves, or gloves.
Gently massage the affected area towards the heart.
Protect the swollen area from injury and keep it clean.
Use lotion or cream to keep the skin moisturized.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Shortness Of Breath

Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):

Tell your doctor immediately if you experience shortness of breath after taking medication.
Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

What if I have taken an overdose of Doxferol D2 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Doxferol D2 Tablet may include nausea, vomiting, feeling tired, difficulty thinking clearly, loss of appetite, increased thirst, constipation, increased urination and weight loss. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Doxferol D2 Tablet if you are allergic to any of its ingredients. Inform about all your medical conditions, sensitivities, and all medications you are using. Doxferol D2 Tablet should not be used in pregnant women or nursing mothers unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy or nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Doxferol D2 Tablet .

Drug-Drug Interactions

DoxercalciferolColecalciferol

Severe

DoxercalciferolCalcitriol

Severe

Drug-Drug Interactions

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DoxercalciferolColecalciferol

Severe

How does the drug interact with Doxferol D2 Tablet:
Cholecalciferol and Doxferol D2 Tablet are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and Doxferol D2 Tablet, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.

DoxercalciferolCalcitriol

Severe

How does the drug interact with Doxferol D2 Tablet:
Co-administration of Doxferol D2 Tablet and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Doxferol D2 Tablet with Calcitriol can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.

DoxercalciferolSucralfate

Severe

How does the drug interact with Doxferol D2 Tablet:
Coadministration of Doxferol D2 Tablet with sulfasalazine can increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Doxferol D2 Tablet and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Consume a well-balanced and healthy diet.
Keep your weight under control with a BMI of 19.5-24.9
Eat low-phosphorus foods such as sourdough bread, corn or rice cereals, cream of wheat, unsalted popcorn and some light-coloured sodas & lemonade.
Avoid high-phosphorus foods, including bran cereals, oatmeal, nuts, sunflower seeds, whole-grain bread and dark-coloured colas.
Limit or avoid alcohol consumption.
Quitting smoking is the best strategy to lower the risk of illness.

Habit Forming

No

Therapeutic Class

VITAMINS

Alcohol

Caution

Consuming alcohol along with Doxferol D2 Tablet is not advisable as it may cause unpleasant side effects.

Pregnancy

Caution

Doxferol D2 Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. So, inform your doctor if you are pregnant and planning to become pregnant; your doctor will prescribe only if the benefits outweigh the risks.

Breast Feeding

Caution

Doxferol D2 Tablet is not recommended for use in breastfeeding women unless necessary. Before taking this medicine, the risks and benefits should be discussed with the doctor. Your doctor may advise you to discontinue the medication or breastfeeding based on your medical condition.

Driving

Caution

It is unknown whether Doxferol D2 Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

Liver

Caution

Caution should be exercised while using Doxferol D2 Tablet in patients with liver disease. Inform your doctor before receiving Doxferol D2 Tablet if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

Kidney

Caution

Care and close monitoring should be exercised when using this agent in patients with severe renal impairment or on dialysis. Inform your doctor before receiving Doxferol D2 Tablet if you have a history of kidney diseases/conditions.

Children

Caution

The safety and efficacy of Doxferol D2 Tablet in pediatric patients have not been established.

Heart

Doxferol D2 Tablet should be used cautiously if you have heart problems, especially irregular heartbeat or high calcium levels, as it may worsen these conditions. Your doctor will likely monitor your heart and calcium levels closely to ensure safe use.

Geriatrics

Caution

Geriatric patients can take Doxferol D2 Tablet , but doctors usually start at a lower dose due to age-related changes in liver and heart function. Regular monitoring of calcium and parathyroid hormone levels is essential to avoid complications like hypercalcemia.

FAQs

What is the use of Doxferol D2 Tablet ?

Doxferol D2 Tablet is used to treat secondary hyperparathyroidism in chronic renal disease patients with or without dialysis therapy.

How does Doxferol D2 Tablet work?

Doxferol D2 Tablet contains Doxercalciferol. It promotes the body's consumption of calcium from food or supplements, as well as the management of parathyroid hormone synthesis.

What is parathyroid hormone?

Parathyroid hormone is secreted by four parathyroid glands, which are tiny glands in the neck positioned behind the thyroid gland.

Is secondary hyperparathyroidism associated with bone disease?

Secondary hyperparathyroidism can cause bone disease. It can also cause calcium to build up in tissues and organs such as the heart and blood vessels.

What are the primary functions of parathyroid glands?

The parathyroid glands generate parathyroid hormone, which is important in regulating calcium levels in the blood. Precise calcium levels are critical in the human body since even minor alterations can cause muscular and nerve issues.

Country of origin

India

Other Info - DOX0552

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:50 AM IST

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Doxferol D2 Tablet 10's

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FAQs

What is the use of Doxferol D2 Tablet ?

How does Doxferol D2 Tablet work?

What is parathyroid hormone?

Is secondary hyperparathyroidism associated with bone disease?

What are the primary functions of parathyroid glands?

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