What is the use of Donnagyl H 250 mg/300 mg Tablet?

Donnagyl H 250 mg/300 mg Tablet is used to treat bacterial and parasitic infections. It kills infection-causing organisms by inhibiting their repair and damaging their DNA.

Is it safe to use Donnagyl H 250 mg/300 mg Tablet?

Yes, Donnagyl H 250 mg/300 mg Tablet is safe to use in most of the patients. However, some may experience side effects such as nausea, vomiting, stomach pain, dizziness, headache, dryness in the mouth, metallic taste and heartburn. If you experience worsening of the side effects or any other symptoms which you think are occurring because of Donnagyl H 250 mg/300 mg Tablet, please consult your doctor.

Can I take Donnagyl H 250 mg/300 mg Tablet in more than recommended dose to recover from symptoms quickly?

No, Donnagyl H 250 mg/300 mg Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.

Can I stop taking Donnagyl H 250 mg/300 mg Tablet if I feel better?

No, it is not advised to stop taking Donnagyl H 250 mg/300 mg Tablet even if you feel better without consulting your doctor. Your symptoms might get improved with time but it is advised to complete the full course of treatment.

What should I do if I forget to take a dose of Donnagyl H 250 mg/300 mg Tablet?

In case, if you forget to take a dose of Donnagyl H 250 mg/300 mg Tablet, take it immediately. However, if it is time to take the next dose, skip the missed dose and continue with the next dose.

Is Donnagyl H 250 mg/300 mg Tablet an antibiotic?

Yes, Donnagyl H 250 mg/300 mg Tablet is a combination antibiotic that includes Ciprofloxacin and Tinidazole. It is used to treat infections caused by susceptible anaerobes, protozoa, gram-negative and gram-positive organisms.

What are the side effects of Donnagyl H 250 mg/300 mg Tablet?

The side effects of Donnagyl H 250 mg/300 mg Tablet include headaches, dizziness, nausea, vomiting, loss of appetite, and tremors. Consult the doctor if any of these side effects persist or worsen.

Is Donnagyl H 250 mg/300 mg Tablet used to treat fever?

No, Donnagyl H 250 mg/300 mg Tablet is used to treat severe bacterial infections and not used for viral infections like a fever.

What should I discuss with my doctor before taking Donnagyl H 250 mg/300 mg Tablet?

You should discuss with your doctor if you have muscle weakness (myasthenia gravis), severe liver disease, lung disease, sleeping disorder or difficulty in sleeping (sleep apnoea), problem with alcohol or other prescription recreational drugs and if you are planning to pregnant, are pregnant or breastfeeding.

What is Donnagyl H 250 mg/300 mg Tablet?

Donnagyl H 250 mg/300 mg Tablet is a combination antibiotic that contains ciprofloxacin and tinidazole used to treat bacterial and parasitic infections.

What if I don't get better after using Donnagyl H 250 mg/300 mg Tablet?

Consult the doctor if you don’t get better after using Donnagyl H 250 mg/300 mg Tablet for the prescribed course of treatment. The doctor may suggest further tests or prescribe alternate medicines.

Can Donnagyl H 250 mg/300 mg Tablet be taken during pregnancy or breastfeeding?

Donnagyl H 250 mg/300 mg Tablet is not recommended during pregnancy or breastfeeding. Please consult the doctor if you are pregnant or breastfeeding.

How soon can I expect results after taking Donnagyl H 250 mg/300 mg Tablet?

You may notice an improvement within two to three days, after taking Donnagyl H 250 mg/300 mg Tablet. But you should finish the prescribed course as directed by your doctor to expect the complete results.

When should I seek medical help while using Donnagyl H 250 mg/300 mg Tablet?

You should seek medical help if you experience allergic reactions such as itching, rashes, swelling, or shortness of breath.

How should I store Donnagyl H 250 mg/300 mg Tablet?

Donnagyl H 250 mg/300 mg Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

Donnagyl H 250 mg/300 mg Tablet

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Donnagyl H 250 mg/300 mg Tablet is indicated in the treatment of bacterial and parasitic infections. It is used to treat a wide variety of infections which are caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes and protozoa. It contains Ciprofloxacin and Tinidazole, which kills bacteria and parasites that are responsible for causing infections. In some cases, you may experience nausea, vomiting, stomach pain, loss of appetite, headache, etc. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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About Donnagyl H 250 mg/300 mg Tablet

Donnagyl H 250 mg/300 mg Tablet is used in the treatment of bacterial and parasitic infections. It is used to treat a wide variety of infections which are caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes and protozoa.

Donnagyl H 250 mg/300 mg Tablet is a combination of two antibiotics that include Ciprofloxacin and Tinidazole. Ciprofloxacin prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Both these actions lead to the killing of the bacteria. Tinidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.

In some cases, you may experience nausea, vomiting, stomach pain, loss of appetite, headache, etc. Most of these side effects of Donnagyl H 250 mg/300 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you experience any symptoms of an allergic reaction, such as rashes, itching, swelling, shortness of breath, etc., please consult your doctor immediately.

It is not advisable to stop this medicine suddenly to avoid unpleasant side effects. Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant or breastfeeding. Also, tell your doctor if you are allergic to this medicine.

Uses of Donnagyl H 250 mg/300 mg Tablet

Treatment of bacterial and parasitic infections.

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Medicinal Benefits

Donnagyl H 250 mg/300 mg Tablet is a combination of two antibiotics that include Ciprofloxacin and Tinidazole. Ciprofloxacin prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Both these actions lead to the killing of the bacteria. Tinidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.

How Donnagyl H 250 mg/300 mg Tablet Works

Donnagyl H 250 mg/300 mg Tablet is a combination of two antibiotics that include Ciprofloxacin and Tinidazole. Ciprofloxacin prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Both these actions lead to the killing of the bacteria. Tinidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Donnagyl H 250 mg/300 mg Tablet

Nausea
Vomiting
Stomach pain
Dryness in the mouth
Metallic taste
Headache

What if I have taken an overdose of Donnagyl H 250 mg/300 mg Tablet

Do not take more than the prescribed dose of Donnagyl H 250 mg/300 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Taking Donnagyl H 250 mg/300 mg Tablet may cause hypersensitivity reactions with symptoms such as rashes, fever, skin reactions, pain in joints, pain in muscles, etc in some individuals. Seek medical help immediately in case you have any of the above adverse reactions on taking the medication.

Drug-Drug Interactions

CiprofloxacinZiprasidone

Critical

CiprofloxacinSotalol

Critical

Drug-Drug Interactions

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CiprofloxacinZiprasidone

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
Coadministration of Donnagyl H 250 mg/300 mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Donnagyl H 250 mg/300 mg Tablet with Ziprasidone is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.

CiprofloxacinSotalol

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
Coadministration of sotalol together with Donnagyl H 250 mg/300 mg Tablet can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Sotalol with Donnagyl H 250 mg/300 mg Tablet is generally avoided as it can result in an interaction, it can be taken together if prescribed by a doctor. However, consult the doctor if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty. Do not discontinue any medications without consulting a doctor.

CiprofloxacinTizanidine

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
Coadministration of Donnagyl H 250 mg/300 mg Tablet and Tizanidine together can increase the risk of side effects.

How to manage the interaction:
Using Donnagyl H 250 mg/300 mg Tablet and Tizanidine together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.

CiprofloxacinQuinidine

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
When Donnagyl H 250 mg/300 mg Tablet is taken with Quinidine, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Donnagyl H 250 mg/300 mg Tablet with Quinidine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

CiprofloxacinDronedarone

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
When Dronedarone is taken with Donnagyl H 250 mg/300 mg Tablet, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Donnagyl H 250 mg/300 mg Tablet with Dronedarone is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

CiprofloxacinFlibanserin

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
When Flibanserin is taken with Donnagyl H 250 mg/300 mg Tablet, it can cause extreme drowsiness and reduces blood pressure that can lead to dizziness, lightheadedness, fainting.

How to manage the interaction:
Taking Donnagyl H 250 mg/300 mg Tablet with Flibanserin is not recommended, but it can be taken if prescribed by the doctor. It is advised to take flibanserin at bedtime to reduce the risk of side effects

CiprofloxacinPimozide

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
When Donnagyl H 250 mg/300 mg Tablet is taken with Pimozide, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Donnagyl H 250 mg/300 mg Tablet with Pimozide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

CiprofloxacinProcainamide

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
Using Donnagyl H 250 mg/300 mg Tablet with Procainamide can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Donnagyl H 250 mg/300 mg Tablet with Procainamide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

CiprofloxacinMesoridazine

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
Using Donnagyl H 250 mg/300 mg Tablet with Mesoridazine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Donnagyl H 250 mg/300 mg Tablet with Mesoridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

CiprofloxacinThioridazine

Critical

How does the drug interact with Donnagyl H 250 mg/300 mg Tablet:
Combining Donnagyl H 250 mg/300 mg Tablet with Thioridazine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Donnagyl H 250 mg/300 mg Tablet with Thioridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

CIPROFLOXACIN-250MG+TINIDAZOLE-300MGCalcium rich foods, Caffeine containing foods/drinks

Moderate

Drug-Food Interactions

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CIPROFLOXACIN-250MG+TINIDAZOLE-300MGCalcium rich foods, Caffeine containing foods/drinks

Moderate

Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt, Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Using caffeine together with ciprofloxacin may increase the effects of caffeine. Taking dairy products such as milk, yogurt, or calcium-fortified foods can make the medication less effective. Avoid taking caffeine with ciprofloxacin, as it causes effects. Contact your doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate. Avoid taking milk, yogurt, or calcium-fortified foods. You could interrupt the feeding for 1 hour before and 2 hours after the ciprofloxacin dose. Do not stop using any medications without talking to your doctor

Diet & Lifestyle Advise

Eat a healthy balanced diet.
Consume high-fibre foods like lentils and beans.
Eat fermented foods like yoghurt and cheese.
Drink plenty of fluids.
Avoid alcohol intake.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Donnagyl H 250 mg/300 mg Tablet Substitute

Ciplox TZ H Tablet 10's
by AYUR
₹9.54per tablet
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₹9.27per tablet
Scalcip TZ 250mg/300mg Tablet
₹3.42per tablet
Ciproxain TZ 250mg/300mg Tablet
₹5.22per tablet
Ciprotini 250 mg/300 mg Tablet
₹5.75per tablet

Alcohol

Caution

It is not recommended consuming alcohol while taking Donnagyl H 250 mg/300 mg Tablet to avoid unpleasant side effects.

Pregnancy

Unsafe

Donnagyl H 250 mg/300 mg Tablet is not recommended in pregnancy. Consult your doctor for further advice.

Breast Feeding

Unsafe

Donnagyl H 250 mg/300 mg Tablet is not recommended in breastfeeding mothers. Consult your doctor for further advice.

Driving

Caution

It is not recommended driving after taking Donnagyl H 250 mg/300 mg Tablet as it can make you feel drowsy.

Liver

Caution

Donnagyl H 250 mg/300 mg Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

Kidney

Caution

Donnagyl H 250 mg/300 mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

Children

Caution

Donnagyl H 250 mg/300 mg Tablet is not recommended in children, unless prescribed by a child specialist.

FAQs

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,India

Other Info - DO26082

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:50 PM IST

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