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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:53 PM IST

Donnagyl H 250 mg/300 mg Tablet is indicated in the treatment of bacterial and parasitic infections. It is used to treat a wide variety of infections which are caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes and protozoa. It contains Ciprofloxacin and Tinidazole, which kills bacteria and parasites that are responsible for causing infections. In some cases, you may experience nausea, vomiting, stomach pain, loss of appetite, headache, etc. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Consume Type

ORAL

Return Policy

Not Returnable

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About Donnagyl H 250 mg/300 mg Tablet

Donnagyl H 250 mg/300 mg Tablet is used in the treatment of bacterial and parasitic infections. It is used to treat a wide variety of infections which are caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes and protozoa.

Donnagyl H 250 mg/300 mg Tablet is a combination of two antibiotics that include Ciprofloxacin and Tinidazole. Ciprofloxacin prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Both these actions lead to the killing of the bacteria. Tinidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.

In some cases, you may experience nausea, vomiting, stomach pain, loss of appetite, headache, etc. Most of these side effects of Donnagyl H 250 mg/300 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you experience any symptoms of an allergic reaction, such as rashes, itching, swelling, shortness of breath, etc., please consult your doctor immediately.

It is not advisable to stop this medicine suddenly to avoid unpleasant side effects. Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant or breastfeeding. Also, tell your doctor if you are allergic to this medicine.

Uses of Donnagyl H 250 mg/300 mg Tablet

Treatment of bacterial and parasitic infections.

Medicinal Benefits

Donnagyl H 250 mg/300 mg Tablet is a combination of two antibiotics that include Ciprofloxacin and Tinidazole. Ciprofloxacin prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Both these actions lead to the killing of the bacteria. Tinidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Donnagyl H 250 mg/300 mg Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Dryness in the mouth
  • Metallic taste
  • Headache

Drug Warnings

Taking Donnagyl H 250 mg/300 mg Tablet may cause hypersensitivity reactions with symptoms such as rashes, fever, skin reactions, pain in joints, pain in muscles, etc in some individuals. Seek medical help immediately in case you have any of the above adverse reactions on taking the medication.

Drug Interactions

Drug-Drug Interaction: This medicine may have an interaction with medicines used to relieve muscle spasms such as tizanidine, medicines used to treat respiratory problems such as theophylline, antidepressants like duloxetine, oral antidiabetic drugs, medicines used to treat seizures such as phenytoin, drugs used for immunosuppression such as cyclosporine and medicines used to treat sleep problems such as zolpidem.

Drug-Food Interaction: Donnagyl H 250 mg/300 mg Tablet may interact with a multi-mineral or other herbal/ayurvedic supplements. So, if you are using any of the OTC items please tell your doctor.

Drug-Disease Interaction: Obese people (with a BMI greater than 25) should consult a doctor before taking Donnagyl H 250 mg/300 mg Tablet.

Drug-Drug Interactions Checker List

  • TIZANIDINE
  • THEOPHYLLINE
  • DULOXETINE
  • PHENYTOIN
  • CYCLOSPORINE
  • ZOLPIDEM

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy balanced diet.
  • Consume high-fibre foods like lentils and beans.
  • Eat fermented foods like yoghurt and cheese.
  • Drink plenty of fluids.
  • Avoid alcohol intake.

Special Advise

  • Donnagyl H 250 mg/300 mg Tablet is prescribed to treat bacterial and parasitic infections, mostly involving but not limited to the infections of the Gastrointestinal system
  • Simultaneous consumption of alcohol while taking this medicine can excessive serious side effects like nausea and vomiting.
  • Maintain your hydration by taking plenty of fluids as GI disorders can lead to dehydration
  • Iron tablets may have an interaction among Donnagyl H 250 mg/300 mg Tablet. Place 2 hours gap between Donnagyl H 250 mg/300 mg Tablet and these supplements to avoid unpleasant effects.
  • Inform your doctor if you are pregnant or planning to get pregnant before consuming this medication. 
  • Consult your doctor in case of persistent side effects post consumption of this medication.

Disease/Condition Glossary

Pneumonia: In this type of infection, there is inflammation of the air sacs in one or both lungs. It can be caused by a variety of organisms which include bacteria, viruses and fungi.

Endocarditis: It is the infection of the inner lining of heart chambers and heart valves. It can occur when micro-organisms such as bacteria, fungi or other germs from other body parts, such as the mouth, spread through the bloodstream and get attached to damaged areas in the heart.

Septic arthritis: It is also known as joint infection or infectious arthritis. In this, there is inflammation of joints due to the invasion of a joint by an infectious agent.

Osteomyelitis: It is an infection of bone which is caused by staphylococcus bacteria which can be found in the nose or skin in healthy individuals.

Meningitis: It is inflammation of meninges in which the membranes covering the brain and spinal cord get inflamed. It occurs due to infection, which can be caused by bacteria or viruses.

Dysentery: It is inflammation of the intestine, particularly the colon, which is caused by the bacteria Shigella.

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Alcohol

Caution

It is not recommended consuming alcohol while taking Donnagyl H 250 mg/300 mg Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

Donnagyl H 250 mg/300 mg Tablet is not recommended in pregnancy. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Donnagyl H 250 mg/300 mg Tablet is not recommended in breastfeeding mothers. Consult your doctor for further advice.

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Driving

Caution

It is not recommended driving after taking Donnagyl H 250 mg/300 mg Tablet as it can make you feel drowsy.

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Liver

Caution

Donnagyl H 250 mg/300 mg Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Donnagyl H 250 mg/300 mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Donnagyl H 250 mg/300 mg Tablet is not recommended in children, unless prescribed by a child specialist.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,India
Other Info - DO26082

Author Details

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FAQs

Donnagyl H 250 mg/300 mg Tablet is used to treat bacterial and parasitic infections. It kills infection-causing organisms by inhibiting their repair and damaging their DNA.
Yes, Donnagyl H 250 mg/300 mg Tablet is safe to use in most of the patients. However, some may experience side effects such as nausea, vomiting, stomach pain, dizziness, headache, dryness in the mouth, metallic taste and heartburn. If you experience worsening of the side effects or any other symptoms which you think are occurring because of Donnagyl H 250 mg/300 mg Tablet, please consult your doctor.
No, Donnagyl H 250 mg/300 mg Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.
No, it is not advised to stop taking Donnagyl H 250 mg/300 mg Tablet even if you feel better without consulting your doctor. Your symptoms might get improved with time but it is advised to complete the full course of treatment.
In case, if you forget to take a dose of Donnagyl H 250 mg/300 mg Tablet, take it immediately. However, if it is time to take the next dose, skip the missed dose and continue with the next dose.
Yes, Donnagyl H 250 mg/300 mg Tablet is a combination antibiotic that includes Ciprofloxacin and Tinidazole. It is used to treat infections caused by susceptible anaerobes, protozoa, gram-negative and gram-positive organisms.
The side effects of Donnagyl H 250 mg/300 mg Tablet include headaches, dizziness, nausea, vomiting, loss of appetite, and tremors. Consult the doctor if any of these side effects persist or worsen.
No, Donnagyl H 250 mg/300 mg Tablet is used to treat severe bacterial infections and not used for viral infections like a fever.
You should discuss with your doctor if you have muscle weakness (myasthenia gravis), severe liver disease, lung disease, sleeping disorder or difficulty in sleeping (sleep apnoea), problem with alcohol or other prescription recreational drugs and if you are planning to pregnant, are pregnant or breastfeeding.
Donnagyl H 250 mg/300 mg Tablet is a combination antibiotic that contains ciprofloxacin and tinidazole used to treat bacterial and parasitic infections.
Consult the doctor if you don’t get better after using Donnagyl H 250 mg/300 mg Tablet for the prescribed course of treatment. The doctor may suggest further tests or prescribe alternate medicines.
Donnagyl H 250 mg/300 mg Tablet is not recommended during pregnancy or breastfeeding. Please consult the doctor if you are pregnant or breastfeeding.
You may notice an improvement within two to three days, after taking Donnagyl H 250 mg/300 mg Tablet. But you should finish the prescribed course as directed by your doctor to expect the complete results.
You should avoid drinking alcohol while taking Donnagyl H 250 mg/300 mg Tablet to prevent unpleasant side effects.
You should seek medical help if you experience allergic reactions such as itching, rashes, swelling, or shortness of breath.
Donnagyl H 250 mg/300 mg Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

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