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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dolopent Injection 1 ml is used to relieve moderate to severe pain. It is indicated in the management of pain severe enough to require an opioid analgesic, for which alternative treatment is inadequate. It is also used as a pre-anaesthetic or pre-operative medication and as a supplement to surgical anaesthesia. It contains Pentazocine, which changes how the nervous system and brain respond to pain. Thereby, it helps provide relief from pain.

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Whats That

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Composition :

PENTAZOCINE-30MG

Manufacturer/Marketer :

Modi Mundipharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Dolopent Injection 1 ml

Dolopent Injection 1 ml belongs to a group of medicines called opiates/narcotic analgesics used to relieve moderate to severe pain. It is indicated in the management of pain severe enough to require an opioid analgesic for which alternative treatment is inadequate. It is also used as a pre-anaesthetic or pre-operative medication and as a supplement to surgical anaesthesia.

Dolopent Injection 1 ml contains ‘Pentazocine’, which works by changing the way the nervous system and brain respond to pain. Thereby, Dolopent Injection 1 ml helps provide relief from pain.

In some cases, Dolopent Injection 1 ml may cause common side effects such as nausea, vomiting, dizziness or lightheadedness and euphoria. You are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating machinery as Dolopent Injection 1 ml may impair the physical and mental ability. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Dolopent Injection 1 ml

Treatment of Pain

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Dolopent Injection 1 ml belongs to a group of medicines called opiates/narcotic analgesics used to relieve moderate to severe pain. It is indicated in the management of pain severe enough to require an opioid analgesic for which alternative treatment is inadequate. It is also used as a pre-anaesthetic or pre-operative medication and as a supplement to surgical anaesthesia. Dolopent Injection 1 ml contains ‘Pentazocine’, which works by changing the way the nervous system and brain respond to pain. Thereby, Dolopent Injection 1 ml helps provide relief from pain.

How Dolopent Injection 1 ml Works

Dolopent Injection 1 ml contains ‘Pentazocine’, which works by changing the way the nervous system and brain respond to pain. Thereby, Dolopent Injection 1 ml helps provide relief from pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dolopent Injection 1 ml

  • Nausea
  • Vomiting
  • Dizziness or lightheadedness
  • Euphoria (a feeling of intense happiness or excitement)

What if I have taken an overdose of Dolopent Injection 1 ml

As Dolopent Injection 1 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Dolopent Injection 1 ml may cause anxiety, dizziness or drowsiness, nightmares, hallucinations, fast heartbeats, tingling sensation, seizures (convulsions), unusual thoughts and very slow breathing.

Drug Warnings

Do not take Dolopent Injection 1 ml if you are allergic to any of its components; if you have significant respiratory depression, acute or severe bronchial asthma in the absence of resuscitative equipment or in an unmonitored setting, gastrointestinal obstruction, including paralytic ileus. Inform your doctor if you have/had liver or kidney problems, adrenal insufficiency, severe hypotension, seizures, myocardial infarction, or biliary surgery. Consult your doctor if you are pregnant or breastfeeding. Concomitant use of opioids with benzodiazepines, and other central nervous system agents, including alcohol, might result in profound sedation, respiratory depression, coma, and death. Dolopent Injection 1 ml may cause serious respiratory depression; hence monitoring is advised.

Drug-Drug Interactions

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PentazocineNaltrexone
Critical
PentazocineHydroxyzine
Severe

Drug-Drug Interactions

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PentazocineNaltrexone
Critical
How does the drug interact with Dolopent Injection 1 ml:
Taking Naltrexone with Dolopent Injection 1 ml can reduce the effects of Dolopent Injection 1 ml and make the medication less effective.

How to manage the interaction:
Taking Dolopent Injection 1 ml with Naltrexone is generally avoided, but can be taken together if prescribed by a doctor. However, if you experience any symptoms like nausea, vomiting, diarrhoea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
PentazocineHydroxyzine
Severe
How does the drug interact with Dolopent Injection 1 ml:
Taking Hydroxyzine with Dolopent Injection 1 ml may increase the risk of serious side effects.

How to manage the interaction:
Taking Dolopent Injection 1 ml with Hydroxyzine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact your doctor immediately. Do not stop using any medications without talking to your doctor.
PentazocineNefazodone
Severe
How does the drug interact with Dolopent Injection 1 ml:
Combining Dolopent Injection 1 ml with Nefazodone may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Dolopent Injection 1 ml with Nefazodone together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
PentazocineBupropion
Severe
How does the drug interact with Dolopent Injection 1 ml:
Taking Bupropion with Dolopent Injection 1 ml can increase the risk of seizures(fits).

How to manage the interaction:
There may be a possibility of interaction between Dolopent Injection 1 ml and Bupropion, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PentazocineVortioxetine
Severe
How does the drug interact with Dolopent Injection 1 ml:
Taking Dolopent Injection 1 ml with Vortioxetine may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Vortioxetine and Dolopent Injection 1 ml, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
PentazocineCodeine
Severe
How does the drug interact with Dolopent Injection 1 ml:
Using Codeine and Dolopent Injection 1 ml may increase the risk of breathing problems.

How to manage the interaction:
Although taking Dolopent Injection 1 ml and Codeine together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PentazocineZolpidem
Severe
How does the drug interact with Dolopent Injection 1 ml:
Using Zolpidem together with Dolopent Injection 1 ml can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Dolopent Injection 1 ml and zolpidem together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
PentazocineEsketamine
Severe
How does the drug interact with Dolopent Injection 1 ml:
Taking Dolopent Injection 1 ml with Esketamine can increase the risk of risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Dolopent Injection 1 ml and Esketamine, but it can be taken if prescribed by a doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PentazocineCitalopram
Severe
How does the drug interact with Dolopent Injection 1 ml:
Taking Dolopent Injection 1 ml with Citalopram can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Co-administration of Dolopent Injection 1 ml with Citalopram can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
PentazocineVilazodone
Severe
How does the drug interact with Dolopent Injection 1 ml:
Taking Dolopent Injection 1 ml with Vilazodone may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Vilazodone with Dolopent Injection 1 ml together can possibly result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fresh fruits and vegetables in your diet.
  • Rest and sleep well.
  • Stay hydrated, and drink plenty of water.
  • Eat anti-inflammatory foods.

Habit Forming

Yes

Therapeutic Class

NARCOTIC (OPIOID) ANALGESIC

Dolopent Injection 1 ml Substitute

Substitutes safety advice
  • Tazowin 1ml Injection

    by AYUR

    43.20per tablet
  • 6Ipzocin 30 mg Injection 1 ml

    62.10per tablet
  • Aeszocin Injection 1 ml

    43.20per tablet
  • Riddof 30 mg Injection 2 ml

    3.19per tablet
  • Pentavin Injection 1 ml

    27.67per tablet
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Alcohol

Unsafe

Avoid the consumption of alcohol, as it may cause profound sedation.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Dolopent Injection 1 ml. Prolonged use of Dolopent Injection 1 ml in pregnancy may cause neonatal opioid withdrawal syndrome.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Dolopent Injection 1 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks. Infants exposed to Dolopent Injection 1 ml through breast milk should be monitored for excessive sedation and respiratory depression. Withdrawal symptoms can develop in breastfed babies when maternal administration of an opioid painkiller is stopped or when nursing is terminated.

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Driving

Unsafe

Dolopent Injection 1 ml may alter your physical and mental ability. Therefore, avoid driving or operating machinery.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Dolopent Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Dolopent Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Caution

Dolopent Injection 1 ml is not recommended for use in children under one year. The doctor will decide the dose of this medicine based on the age, body weight and clinical condition of your child.

FAQs

Dolopent Injection 1 ml is used to treat Pain.
Dolopent Injection 1 ml works by changing the way the nervous system and brain respond to pain.
Dolopent Injection 1 ml may cause respiratory depression. Monitoring for respiratory depression during the initiation of treatment or following a dose increase is advised.
It is contraindicated for use in patients with known or suspected gastrointestinal obstruction, including paralytic ileus. Consult your doctor if you have any concerns.
While on therapy with Dolopent Injection 1 ml, be cautious if you have experience drowsiness and dizziness, or if you have breathing problems, and avoid driving or operating heavy machinery. Inform your doctor, if you have respiratory depression, asthma, gastrointestinal obstruction, liver or kidney issues, low blood pressure, seizures, heart problems, or a history of biliary surgery. Consult your doctor if pregnant or breastfeeding. Be aware of the potential for dependence or withdrawal symptoms with prolonged use of Dolopent Injection 1 ml with opioids, benzodiazepines, alcohol, or other CNS depressants, as they can cause severe sedation and breathing problems. Therefore, monitoring is recommended due to the risk of respiratory depression.
Dolopent Injection 1 ml causes side effects such as nausea, vomiting, dizziness or lightheadness, and euphoria (a feeling of intense happiness or excitement). However, please contact a doctor if these side effects persist for longer durations.

Country of origin

INDIA

Manufacturer/Marketer address

Ground Floor Modi Tower, 98, Nehru Place, New Delhi, Delhi 110019.
Other Info - DOL0465

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