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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Dolonex E 90 Tablet is used to treat pain, swelling and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout in people greater than 16 years of age. Besides this, it is also used to treat moderate pain after dental surgery. It contains Etoricoxib, which works by blocking the release of a chemical messenger called prostaglandin, responsible for pain, swelling and inflammation. It may cause common side effects such as stomach pain, dry socket, swelling of the legs, dizziness, headache, palpitations (pounding heart), increased blood pressure, shortness of breath, constipation, flatulence, gastritis (inflammation of the lining of the stomach), heartburn, diarrhoea, indigestion (dyspepsia), nausea, vomiting, inflammation of the oesophagus (food pipe), mouth ulcers, general weakness and flu-like illness (fever, cold, cough, or sore throat).
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Prescription drug

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Prescription drug
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Composition

ETORICOXIB-90MG

Manufacturer/Marketer

Pfizer Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Dolonex E 90 Tablet

Dolonex E 90 Tablet is used to treat pain, swelling and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout in people greater than 16 years of age. Besides this, it is also used to treat moderate pain after dental surgery. Osteoarthritis is a degenerative bone disease in which the tissue supporting the joints wears down. Rheumatoid arthritis is a condition in which the immune system attacks its tissue, leading to joint pain and inflammation. Ankylosing spondylitis is the inflammation of the spine and large joints. Gout is characterized by pain and inflammation in the joints due to the deposition of uric acid crystals.

Dolonex E 90 Tablet contains ‘etoricoxib’, which works by blocking the release of a chemical messenger called prostaglandin, produced by COX-2, which is responsible for pain, swelling and inflammation. Dolonex E 90 Tablet acts at the affected area and acts specifically at the pain site. The benefit of COX-2 inhibitors is that they protect the stomach lining from the ulcer effect caused by other painkillers, ibuprofen and aspirin.

Dolonex E 90 Tablet is available in tablet form and injection. Take an oral form of Dolonex E 90 Tablet as advised by your doctor. A healthcare professional will give the injection form of Dolonex E 90 Tablet , do not self-administer. Common side-effects of Dolonex E 90 Tablet are stomach pain, dry socket, swelling of the legs, dizziness, headache, palpitations (pounding heart), increased blood pressure, shortness of breath, constipation, flatulence, gastritis (inflammation of the lining of the stomach), heartburn, diarrhoea, indigestion (dyspepsia), nausea, vomiting, inflammation of the oesophagus (food pipe), mouth ulcers, general weakness and flu-like illness (fever, cold, cough, or sore throat).

Do not take Dolonex E 90 Tablet if you are allergic to etoricoxib, other pain killers or other ingredients. Inform your doctor if you have ulcers or bleeding in your stomach, severe liver and/or kidney impairment, colitis (inflammation of the large intestine), uncontrolled blood pressure, or heart problems such as chest pain, heart attack, heart failure and stroke. Do not take it if you are under 16 years of age, pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you are dehydrated (because of vomiting or diarrhoea), have oedema (swelling due to fluid retention), have an infection, diabetes (high blood sugar) and high cholesterol, are a smoker or have an age above 65 years.

Uses of Dolonex E 90 Tablet

Treatment of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Gout.

Medicinal Benefits

Dolonex E 90 Tablet contains ‘etoricoxib’ which is a non-steroidal anti-inflammatory drug (NSAID). It acts as both analgesic (reduces pain) and an anti-inflammatory (reduces inflammation) agent. It is a selective COX-2 inhibitor. COX-2 enzymes are responsible for converting arachidonic acid to prostaglandins which are inflammatory mediators. The blocking of COX-2 reduces the production of prostaglandins, eventually decreasing pain and inflammation.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dolonex E 90 Tablet

  • Stomach pain

  • Dry socket (severe pain after tooth extraction)
  • Swelling of the legs or feet due to fluid retention (oedema)
  • Dizziness
  • Headache
  • Palpitations (pounding heart)
  • Increased blood pressure
  • Wheezing or shortness of breath
  • Constipation
  • Flatulence
  • Gastritis (inflammation of the lining of the stomach)
  • Heartburn
  • Diarrhoea
  • Indigestion (dyspepsia)
  • Nausea (feeling sick)
  • Vomiting (being sick)
  • Inflammation of the oesophagus (food pipe)
  • Mouth ulcers
  • Changes in blood tests related to your liver
  • Weakness
  • Fatigue (tiredness)
  • Flu-like illness (fever, cold, cough, or sore throat)

Drug Warnings

Before taking Dolonex E 90 Tablet , inform your doctor if you have a history of stomach bleeding or ulcer, liver or kidney diseases, dehydration because of prolonged vomiting or diarrhoea and swelling due to fluid retention. Inform your doctor if you have high blood pressure that is not treated or controlled, as Dolonex E 90 Tablet may increase blood pressure in some cases. Do not take Dolonex E 90 Tablet if you are treated for infection, as Dolonex E 90 Tablet can mask fever (a sign of disease). Do not take Dolonex E 90 Tablet if you smoke, have diabetes (high blood sugar), or high cholesterol, as Dolonex E 90 Tablet increases the risk of heart attack or stroke. Avoid lying down for at least half an hour after using Dolonex E 90 Tablet . People who have had heart attacks and strokes should not take Dolonex E 90 Tablet .

Drug Interactions

Drug-Drug interactions: Dolonex E 90 Tablet may interact with anticoagulant (warfarin and aspirin), antibiotic (rifampicin), immunosuppressant (methotrexate), antihypertensives (enalapril, ramipril, losartan, valsartan, and minoxidil), diuretics, antiarrhythmic drug (digoxin), antiasthmatic drug (salbutamol) and oral contraceptives.

Drug-Food interactions: No interactions found.

Drug-Disease interactions: Dolonex E 90 Tablet should be used with caution in patients with stomach ulcers or bleeding, severe kidney disease, liver diseases, colitis (inflammation of the large intestine), uncontrolled blood pressure, heart failure, stroke, and other heart problems.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • RIFAMPICIN
  • METHOTREXATE
  • ENALAPRIL
  • RAMIPRIL
  • LOSARTAN
  • VALSARTAN
  • MINOXIDIL
  • DIGOXIN
  • SALBUTAMOL

Habit Forming

No

Diet & Lifestyle Advise

  • Consume a healthy diet that includes fresh fruits and vegetables. Limit foods high in sugar content.
  • Do not take spicy, fried and processed foods.
  • Drink plenty of water to stay hydrated. 
  • Quit smoking.
  • Limit caffeine and alcohol intake.

Special Advise

  • Your doctor may monitor liver and kidney function if Dolonex E 90 Tablet is prescribed for the long term. 

  • Inform your doctor before taking the Dolonex E 90 Tablet if you had a history of a heart attack, bypass surgery or peripheral arterial disease.

Disease/Condition Glossary

Osteoarthritis: Osteoarthritis is the common type of arthritis in which the cartilage that cushions the ends of the bones erodes due to wear and tear over time. Common symptoms are joint pain and stiffness.

Rheumatoid arthritis (RA): Rheumatoid arthritis (RA) is an autoimmune disease in which the immune cells attack the joints and cause bone erosion leading to severe pain and swelling. It may lead to joint deformity if left untreated.

Ankylosing spondylitis: Ankylosing spondylitis is a type of arthritis in which inflammation is seen in the spine and large joints. It leads to pain and stiffness in the back and affected joints.

Gout: Gout is an inflammatory condition in which uric acid deposits and crystallizes in the joints. It is characterized by acute, severe and recurring attacks of pain, especially at night; redness and swelling in the affected joints.

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Alcohol

Caution

Alcohol intake may increase the risk of heart problems when using Dolonex E 90 Tablet .

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Pregnancy

Unsafe

Dolonex E 90 Tablet is a category C medicine. It shows toxic effects on the fetus when given to pregnant women. Consult your doctor for further advice.

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Breast Feeding

Caution

Dolonex E 90 Tablet should be used with caution in breastfeeding mothers and only when prescribed by a doctor.

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Driving

Caution

Dolonex E 90 Tablet may cause dizziness. So, you should not drive or operate heavy machinery after taking Dolonex E 90 Tablet .

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Liver

Caution

Dolonex E 90 Tablet may alter liver function. So, dose adjustments are necessary for patients with liver diseases.

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Kidney

Caution

Dolonex E 90 Tablet should be used with caution in patients with kidney diseases. Dosage adjustments are necessary for patients with severe renal impairment.

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Children

Unsafe

Dolonex E 90 Tablet is not recommended for children below 16 years of age.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ?G? Block , Bandra Kurla Complex, Bandra East , Mumbai ? 400051.
Other Info - DOL0498

Author Details

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FAQs

Dolonex E 90 Tablet is used to treat pain, swelling and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout in people greater than 16 years of age. Besides this, it is also used to treat moderate pain after dental surgery.
Dolonex E 90 Tablet contains ‘etoricoxib’, which is a non-steroidal anti-inflammatory drug (NSAID). It is a COX-2 inhibitor. COX-2 enzyme produces prostaglandins that cause pain, swelling and inflammation.
You should not take Dolonex E 90 Tablet for the longer term, especially in higher doses, as it increases the risk of heart attack and stroke.
Dolonex E 90 Tablet may cause dizziness. So, driving or operating heavy machinery is not advisable after taking Dolonex E 90 Tablet .
Dolonex E 90 Tablet is not recommended for use in children below 16 years of age.
Dolonex E 90 Tablet may increase blood pressure, especially in high doses. It should not be given to patients with uncontrolled blood pressure, heart problems or recent heart surgeries.
Dolonex E 90 Tablet is a pain killer that helps to reduce pain and inflammation in joint disorder conditions. However, taking it without a doctor's advice is not recommended.
Talk to your healthcare professional before taking Etoricoxib if you have any underlying medical condition or are taking any medications. Also, ask for advice about precautions and limitations of Dolonex E 90 Tablet .
The risk of stomach ulcers is greater if you take Etoricoxib with aspirin. So, exercise caution.
The time it takes to see results with Dolonex E 90 Tablet may vary depending on many factors. It's important to follow the recommended dosage and treatment regimen and to consult with a healthcare professional for ongoing monitoring.
Dolonex E 90 Tablet is usually taken orally. Swallow the tablet as a whole with a glass of water. Do not crush, chew or break it. Take it at the same time every day for effective results.
Dizziness and sleepiness have been reported in some patients taking Dolonex E 90 Tablet . Do not drive if you experience dizziness or sleepiness.
Dolonex E 90 Tablet may increase the incidence of adverse events associated with oral contraceptives.
Dolonex E 90 Tablet contains Etoricoxib, is a COX 2 inhibitor with an onset of action at 20–30 minutes, with a duration of action of ≥ 24 hours.
Yes, Dolonex E 90 Tablet contains etoricoxib, which is a non-steroidal anti-inflammatory drug (NSAID) or painkiller.
Long-term use of Dolonex E 90 Tablet may have resulted in renal papillary necrosis and other renal injuries. Patients on long term treatment should be reviewed regularly
Yes, Dolonex E 90 Tablet can be taken with food.
Dolonex E 90 Tablet may alter liver function. So, dose adjustments are necessary for patients with liver diseases.
Common side-effects of Dolonex E 90 Tablet are stomach pain, dry socket, swelling of the legs, dizziness, headache, palpitations (pounding heart), increased blood pressure, shortness of breath, constipation, flatulence, gastritis (inflammation of the lining of the stomach), heartburn, diarrhoea, indigestion (dyspepsia), nausea, vomiting, inflammation of the oesophagus (food pipe), mouth ulcers, general weakness and flu-like illness (fever, cold, cough, or sore throat).
Before taking the Dolonex E 90 Tablet , let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Dolonex E 90 Tablet can interact with various medicines. So, do not consume any other medications along with Dolonex E 90 Tablet unless recommended by the doctor.
Dolonex E 90 Tablet contains Etoricoxib, a selective COX-2 inhibitor relieves inflammatory and painful symptoms.
If you forget to take a dose of Dolonex E 90 Tablet , take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Do not take more than the prescribed dose of Dolonex E 90 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

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