Doloneuron 300 Tablet belongs to a class of 'anticonvulsants,' primarily used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia. Epilepsy is a neurological condition in which the brain's activity becomes abnormal with seizure episodes, sometimes losing awareness or consciousness. Neuralgia is a chronic pain condition of the nerves that occurs due to nerve damage or other neurological conditions like neuropathy, trigeminal neuralgia or shingles.

Doloneuron 300 Tablet consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Doloneuron 300 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Your doctor will decide the dosage and duration based on your medical condition. Sometimes, Doloneuron 300 Tablet may have common side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Let your doctor know if you are using any prescription, non-prescription drugs, and herbal products before starting Doloneuron 300 Tablet . If you are a pregnant or breastfeeding mother, please consult your doctor before taking Doloneuron 300 Tablet . Doloneuron 300 Tablet causes drowsiness and dizziness, so drive only if you are alert. Doloneuron 300 Tablet should not be given to children under three years old as safety and effectiveness have not been established. Avoid consuming alcohol along with Doloneuron 300 Tablet as it could lead to increased dizziness and sleepiness. 

Doloneuron 300 Tablet is used to treat post-herpetic neuralgia and epilepsy. It contains Gabapentin (anti-convulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain and lowers the risk of seizures. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also used to treat alcoholic neuropathy and diabetic neuropathy (nerve damage due to high blood sugar levels).

• Dizziness

• Sleepiness

• Tiredness

• Nausea 

• Vomiting 

Inform your doctor before taking Doloneuron 300 Tablet if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Consult your doctor if you are on haemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea, and vomiting. Please do not stop taking Doloneuron 300 Tablet without consulting your doctor as it could cause withdrawal symptoms. Pregnant and breastfeeding women should consult their doctor before taking Doloneuron 300 Tablet . Consult your doctor immediately if you experience suicidal tendencies. Keep Doloneuron 300 Tablet away from direct sunlight. Do not store Doloneuron 300 Tablet above 25ºC and keep it away from direct sunlight.

Drug-Drug Interaction: Doloneuron 300 Tablet may interact with pain killers (hydrocodone, acetaminophen), antidepressants (duloxetine, escitalopram, sertraline), muscle relaxants (cyclobenzaprine), anti-anxiety drugs (alprazolam), fits medicines (pregabalin), antipsychotics (quetiapine), antibiotics (chloramphenicol), and anti-diabetics (metformin).

Drug-Food Interaction: Avoid alcohol consumption while taking Doloneuron 300 Tablet as it might cause increased dizziness and sleepiness.

Drug-Disease Interaction: Doloneuron 300 Tablet may interact with disease conditions such as suicidal tendencies, renal dysfunction, and haemodialysis.

• HYDROCODONE
• ACETAMINOPHEN
• DULOXETINE
• ESCITALOPRAM
• SERTRALINE
• CYCLOBENZAPRINE
• ALPRAZOLAM
• PREGABALIN
• QUETIAPINE
• CHLORAMPHENICOL
• METFORMIN

• Include food rich in vitamin B and D in your diet as they can help in improving nerve health and preventing nerve pain.

• Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

• Exercising regularly helps in improving overall health and combating pain. 

• Rest well; get plenty of sleep.

• Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreases numbness and pain.

• Avoid smoking and alcohol consumption.

• Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

• Physical relaxation and massages can help provide symptomatic relief.

• Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.

• Acupuncture can be helpful by stimulating pressure points.

• Using essential oils for massages can help increase circulation and boosts healing.

• Close monitoring for suicidal thoughts/behaviour is required in people using Doloneuron 300 Tablet . 

• Using Doloneuron 300 Tablet in children 3-12 years of age can cause emotional changes, aggressive behaviour, concentration problems, restlessness, school performance changes, and hyperactivity. 

• Let your doctor and the laboratory staff know if you are using Doloneuron 300 Tablet since Gabapentin may interfere with laboratory tests. 

Epilepsy is the central nervous system's disorder in which brain activity becomes abnormal, leading to rapid fits/seizures episodes with unusual behaviour and loss of awareness. Fits/Seizure is a sudden rush of electrical activity in the brain. The main symptom of epilepsy fits.

Neuropathic pain: It is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).