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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Doloneuron 300 Tablet is used to treat neuropathic pain. It contains Gabapentin and Methylcobalamin which rejuvenate and protect damaged nerve cells. In some cases, this medicine may cause side effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Pulse Pharmaceuticals

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Doloneuron 300 Tablet

Doloneuron 300 Tablet belongs to a class of 'anticonvulsants,' primarily used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia. Epilepsy is a neurological condition in which the brain's activity becomes abnormal with seizure episodes, sometimes losing awareness or consciousness. Neuralgia is a chronic pain condition of the nerves that occurs due to nerve damage or other neurological conditions like neuropathy, trigeminal neuralgia or shingles.

Doloneuron 300 Tablet consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Doloneuron 300 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Your doctor will decide the dosage and duration based on your medical condition. Sometimes, Doloneuron 300 Tablet may have common side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Let your doctor know if you are using any prescription, non-prescription drugs, and herbal products before starting Doloneuron 300 Tablet . If you are a pregnant or breastfeeding mother, please consult your doctor before taking Doloneuron 300 Tablet . Doloneuron 300 Tablet causes drowsiness and dizziness, so drive only if you are alert. Doloneuron 300 Tablet should not be given to children under three years old as safety and effectiveness have not been established. Avoid consuming alcohol along with Doloneuron 300 Tablet as it could lead to increased dizziness and sleepiness. 

Uses of Doloneuron 300 Tablet

Treatment of Neuropathic pain and Epilepsy (fits).

Directions for Use

Take Doloneuron 300 Tablet with or without food. Swallow it as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Doloneuron 300 Tablet is used to treat post-herpetic neuralgia and epilepsy. It contains Gabapentin (anti-convulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain and lowers the risk of seizures. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also used to treat alcoholic neuropathy and diabetic neuropathy (nerve damage due to high blood sugar levels).

How Doloneuron 300 Tablet Works

Doloneuron 300 Tablet consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Doloneuron 300 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Doloneuron 300 Tablet

  • Dizziness

  • Sleepiness

  • Tiredness

  • Nausea 

  • Vomiting 

What if I have taken an overdose of Doloneuron 300 Tablet

Take Doloneuron 300 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor before taking Doloneuron 300 Tablet if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Consult your doctor if you are on haemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea, and vomiting. Please do not stop taking Doloneuron 300 Tablet without consulting your doctor as it could cause withdrawal symptoms. Pregnant and breastfeeding women should consult their doctor before taking Doloneuron 300 Tablet . Consult your doctor immediately if you experience suicidal tendencies. Keep Doloneuron 300 Tablet away from direct sunlight. Do not store Doloneuron 300 Tablet above 25ºC and keep it away from direct sunlight.

Drug-Drug Interactions

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GabapentinBuprenorphine
Severe
GabapentinFentanyl
Severe

Drug-Drug Interactions

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GabapentinBuprenorphine
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Co-administration of Buprenorphine and Doloneuron 300 Tablet 10's may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Doloneuron 300 Tablet 10's and Buprenorphine, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
GabapentinFentanyl
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Taking fentanyl with other drugs that cause central nervous system depression, such as Doloneuron 300 Tablet 10's, might result in an increased risk of adverse effects.

How to manage the interaction:
Although combining Fentanyl and Doloneuron 300 Tablet 10's may cause an interaction, they can be used if advised by your doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
GabapentinPethidine
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Combining Meperidine with Doloneuron 300 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
Co-administration of Pethidine with Doloneuron 300 Tablet 10's can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
GabapentinPentazocine
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Taking Pentazocine with Doloneuron 300 Tablet 10's can increase the risk of serious side effects.

How to manage the interaction:
Although taking Pentazocine and Doloneuron 300 Tablet 10's together can evidently cause an interaction, but it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact a doctor immediately. Do not stop using any medications without talking to a doctor.
GabapentinSufentanil
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Combining Sufentanil with Doloneuron 300 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
There may be a possibility of interaction between Doloneuron 300 Tablet 10's and Sufentanil, but it can be taken if prescribed by a doctor. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any symptoms like trouble breathing, feeling dizzy or tired, or having trouble focusing, make sure to call your doctor right away. Do not discontinue any medications without first consulting your doctor.
GabapentinTramadol
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Co-administration of Tramadol with Doloneuron 300 Tablet 10's may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Doloneuron 300 Tablet 10's and Tramadol, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, please consult your doctor immediately. Do not discontinue any medications without a doctor's advice.
GabapentinEsketamine
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Combining Doloneuron 300 Tablet 10's with Esketamine can increase the risk of side effects.

How to manage the interaction:
Although taking Doloneuron 300 Tablet 10's and Esketamine together can evidently cause an interaction, it can be taken if a doctor has suggested it. Consult a doctor if you experience any symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not stop using any medications without a doctor's advice.
GabapentinCodeine
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Combining Codeine with Doloneuron 300 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
Taking Doloneuron 300 Tablet 10's with Codeine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, feeling dizzy or tired, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinRemifentanil
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Combining Remifentanil with Doloneuron 300 Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Doloneuron 300 Tablet 10's with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
GabapentinButorphanol
Severe
How does the drug interact with Doloneuron 300 Tablet 10's:
Co-administration of Butorphanol and Doloneuron 300 Tablet 10's may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Doloneuron 300 Tablet 10's and Butorphanol, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, please consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet as they can help in improving nerve health and preventing nerve pain.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well; get plenty of sleep.

  • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreases numbness and pain.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Physical relaxation and massages can help provide symptomatic relief.

  • Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation and boosts healing.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Doloneuron 300 Tablet Substitute

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  • Gabantin Forte Tablet 10's

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  • Pentanerv M Tablet 10's

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Doloneuron 300 Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Doloneuron 300 Tablet is not recommended during pregnancy unless prescribed by a doctor. Let your doctor know if you are pregnant or planning to conceive before taking Doloneuron 300 Tablet .

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Breast Feeding

Caution

Gabapentin in Doloneuron 300 Tablet is excreted into breast milk. Please consult your doctor before taking Doloneuron 300 Tablet if you are breastfeeding.

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Driving

Unsafe

Doloneuron 300 Tablet causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are mentally and physically alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Doloneuron 300 Tablet . Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Doloneuron 300 Tablet . Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

Doloneuron 300 Tablet is not recommended in children less than three years of age. The doctor will prescribe the dosage of Doloneuron 300 Tablet based on the child's age and weight.

FAQs

Doloneuron 300 Tablet is used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia.
Doloneuron 300 Tablet works by controlling the abnormal electrical activity of the brain that causes seizures (fits). It also helps in the rejuvenation and protection of damaged nerve cells.
Doloneuron 300 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a balanced diet.
People taking Doloneuron 300 Tablet should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
If Doloneuron 300 Tablet is taken along with antacid medicines containing aluminium and magnesium, it may lower the absorption of Doloneuron 300 Tablet from the stomach. To avoid this, maintain a gap of two hours between Doloneuron 300 Tablet and antacid medicines.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Neuropathic pain is a chronic progressive nerve disease that occurs due to damaged sensory nerves. Neuropathic pain is stabbing, tingling, and sharp while muscle pain is dull and steady or crampy and spasmodic.
Inform your doctor before taking Doloneuron 300 Tablet if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Pregnant and breastfeeding women should consult their doctor before taking Doloneuron 300 Tablet .
Doloneuron 300 Tablet is a combination medicine containing Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). It is used to treat neuropathic pain.
Peripheral neuropathy affects the nerves outside your brain or spinal cord. It causes tingling sensation, pain, numbness and burning sensation.
Do not discontinue Doloneuron 300 Tablet without consulting your doctor. To treat your condition effectively, keep taking Doloneuron 300 Tablet for the prescribed duration.
Doloneuron 300 Tablet may cause sleepiness as a side effect. Do not drive or operate machinery unless you are alert.
No, do not take a higher than the recommended dose of Doloneuron 300 Tablet as it might cause an overdose. Take Doloneuron 300 Tablet in the dose and duration prescribed by the doctor.
Store Doloneuron 300 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Doloneuron 300 Tablet may cause side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Country of origin

INDIA

Manufacturer/Marketer address

4F10, Ballad Estates, Tarnaka, Hyderabad - 500017, TS, India.
Other Info - DOL0002

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