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Reviewed By Veda Maddala , M Pharmacy
DOCETRUST 120MG INJECTION 3ML is an anti-cancer medicine used in the treatment of breast, lung, prostate, stomach, head/neck cancers. It works by slowing down cell growth, thus preventing the cancer cells from rapidly dividing and spreading. Common side effects include injection site reactions, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, etc.
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Composition :

DOCETAXEL-120MG

Manufacturer/Marketer :

Panacea Biotec Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About DOCETRUST 120MG INJECTION 3ML

DOCETRUST 120MG INJECTION 3ML belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

DOCETRUST 120MG INJECTION 3ML contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

DOCETRUST 120MG INJECTION 3ML will be administered by a healthcare professional. Your doctor will decide the dosage depending on your medical condition. The common side effects of DOCETRUST 120MG INJECTION 3ML include pain/swelling at the injection site, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, insomnia (sleeplessness), fever (please inform your doctor if you have fever), muscle aches, and breathlessness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use or stop this medicine if the doctor did not advise you. Before starting DOCETRUST 120MG INJECTION 3ML, let your doctor know if you have any allergic reactions, medical history of liver or kidney diseases, heart diseases, blood pressure problems, fits, lung disorders, weak immune system, anemia, low white blood cell count, vision problems, and are receiving chemotherapy. DOCETRUST 120MG INJECTION 3ML is not indicated for use in pregnant and breastfeeding women. DOCETRUST 120MG INJECTION 3ML may make you feel dizzy and drowsy, hence do not drive or operate machinery. It is not recommended to consume alcohol along with DOCETRUST 120MG INJECTION 3ML. DOCETRUST 120MG INJECTION 3ML is not recommended for children below two years of age.

Uses of DOCETRUST 120MG INJECTION 3ML

Treatment of Cancer

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

DOCETRUST 120MG INJECTION 3ML contains Docetaxel that belongs to the family of anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent and prevents cancer cells from rapidly dividing and spreading. Docetaxel may be used alone or in combination with other chemotherapy drugs to treat breast cancer that has spread to the tissues and lymph nodes (locally advanced breast cancer) and other parts (secondary breast cancer). It is also used in prostate cancer that does not respond to hormone treatment. It is further being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers.

How DOCETRUST 120MG INJECTION 3ML Works

DOCETRUST 120MG INJECTION 3ML contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DOCETRUST 120MG INJECTION 3ML

  • Pain/swelling at the injection site
  • Headache
  • Fatigue
  • Dizziness
  • Drowsiness
  • Constipation
  • Loss of appetite
  • Indigestion
  • Tearing of the eyes
  • Nausea
  • Vomiting
  • Diarrhoea
  • Insomnia (sleeplessness)
  • Fever (please inform your doctor if you have fever)
  • Muscle aches
  • Breathlessness

What if I have taken an overdose of DOCETRUST 120MG INJECTION 3ML

The overdose of DOCETRUST 120MG INJECTION 3ML is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with DOCETRUST 120MG INJECTION 3ML, please inform your doctor immediately.

Drug Warnings

Inform your doctor if you have any allergic reactions to DOCETRUST 120MG INJECTION 3ML or other medications. Before starting DOCETRUST 120MG INJECTION 3ML, let your doctor know if you have any medical history of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. DOCETRUST 120MG INJECTION 3ML can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, DOCETRUST 120MG INJECTION 3ML is not indicated in pregnancy and breastfeeding women. If you are using DOCETRUST 120MG INJECTION 3ML, use reliable contraception forms to prevent pregnancy during the course. DOCETRUST 120MG INJECTION 3ML can make you feel dizzy and drowsy, thus affecting your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with DOCETRUST 120MG INJECTION 3ML. DOCETRUST 120MG INJECTION 3ML is not recommended for patients younger than 18 years of age.

Drug-Drug Interactions

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DocetaxelTofacitinib
Severe
DocetaxelItraconazole
Severe

Drug-Drug Interactions

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DocetaxelTofacitinib
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
Taking Tofacitinib with DOCETRUST 120MG INJECTION 3ML may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and DOCETRUST 120MG INJECTION 3ML, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
DocetaxelItraconazole
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
Coadministration of Itraconazole may significantly increase the blood levels of DOCETRUST 120MG INJECTION 3ML.

How to manage the interaction:
Although there is a possible interaction between DOCETRUST 120MG INJECTION 3ML and Itraconazole, they can be taken in case a doctor prescribes it. Consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating. Never stop taking any medications without talking to a doctor.
DocetaxelVerapamil
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
Taking verapamil with DOCETRUST 120MG INJECTION 3ML may significantly increase the blood levels of DOCETRUST 120MG INJECTION 3ML. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking DOCETRUST 120MG INJECTION 3ML and Verapamil together may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, mouth sores, fluid retention, nerve pain, numbness, tingling, muscle pain or weakness, paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medication without consulting a doctor.
DocetaxelCeritinib
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
Taking ceritinib and may significantly increase the blood levels of DOCETRUST 120MG INJECTION 3ML.

How to manage the interaction:
Taking DOCETRUST 120MG INJECTION 3ML with Ceritinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like nausea, vomiting, diarrhea, mouth sores, fluid retention, nerve pain, numbness, tingling, muscle pain or weakness, paleness, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to a doctor.
DocetaxelDiltiazem
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
When Diltiazem is taken with DOCETRUST 120MG INJECTION 3ML, it can slow down the breakdown of DOCETRUST 120MG INJECTION 3ML in the body.

How to manage the interaction:
Taking Diltiazem with DOCETRUST 120MG INJECTION 3ML together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like feeling sick, throwing up, having diarrhea, mouth sores, swelling, nerve pain, or weakness, it's important to let your doctor know. They might have other options for you that won't cause these problems. Other symptoms like feeling tired, dizzy, or having trouble breathing, losing weight, or pain when you pee should also be reported to your doctor right away. Do not stop using any medications without first talking to your doctor.
DocetaxelClarithromycin
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
When DOCETRUST 120MG INJECTION 3ML is taken with Clarithromycin, it can slow down the way the body breaks down DOCETRUST 120MG INJECTION 3ML.

How to manage the interaction:
Taking Clarithromycin with DOCETRUST 120MG INJECTION 3ML together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - feeling sick, throwing up, having diarrhea, mouth sores, retaining fluids, nerve pain, numbness, tingling, muscle pain, weakness, anemia, bleeding problems, looking pale, feeling tired, dizzy, bleeding, bruising, having a fever, chills, a sore throat, muscle aches, trouble breathing, losing weight, feeling pain or burning when you pee, or bleeding - make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
DocetaxelTofacitinib
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
When Tofacitinib is taken with DOCETRUST 120MG INJECTION 3ML, the body's ability to break down Tofacitinib may be reduced.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and DOCETRUST 120MG INJECTION 3ML, you can take these medicines together if prescribed by your doctor. "If you are taking tofacitinib along with other drugs that weaken your immune system, it is important to be closely monitored for any signs of infection. This includes the possibility of getting tuberculosis, even if you tested negative for it before starting the medication." Do not stop using any medications without first talking to your doctor.
DocetaxelVoriconazole
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
Taking DOCETRUST 120MG INJECTION 3ML with Voriconazole may significantly increase the blood levels of DOCETRUST 120MG INJECTION 3ML.

How to manage the interaction:
Although taking DOCETRUST 120MG INJECTION 3ML and Voriconazole together may result in an interaction, they can be taken together if a doctor prescribes it. However, if you experience dizziness, fever, chills, diarrhea, sore throat, muscle pain, shortness of breath, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
DocetaxelErythromycin
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
Erythromycin may significantly increase DOCETRUST 120MG INJECTION 3ML blood levels. This may increase the possibility of DOCETRUST 120MG INJECTION 3ML side effects.

How to manage the interaction:
Although taking erythromycin and ceritinib together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience fatigue, confusion, unusual bruising or bleeding, fever, shivers, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, urination discomfort or burning. Do not discontinue any medications without consulting a doctor.
DocetaxelPosaconazole
Severe
How does the drug interact with DOCETRUST 120MG INJECTION 3ML:
Taking DOCETRUST 120MG INJECTION 3ML with posaconazole can increase the blood levels of DOCETRUST 120MG INJECTION 3ML. This may increase the risk of side effects.

How to manage the interaction:
Although using Posaconazole and DOCETRUST 120MG INJECTION 3ML together can result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience vomiting, diarrhea, mouth sores, nerve pain, numbness, tingling, muscle pain or weakness. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Include whole grains, legumes, and follow a plant-based diet. Limiting dietary fats is advised during the breast cancer phase. Instead, include healthy fats, such as olive oil, avocado, nuts, seeds, and fatty fish
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk, and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

DOCETRUST 120MG INJECTION 3ML Substitute

Substitutes safety advice
  • DTAXANE 120MG INJECTION 3ML

    4205.51per tablet
  • SOLVENT FOR DOCETERE 120MG INJECTION

    29.16per tablet
  • SOLVENT FOR DAXOTEL 120MG INJECTION

    36.00per tablet
  • ZENOTERE 120MG VIAL INJECTION 3.0ML

    3200.19per tablet
  • TUBITERE 120MG INJECTION 0.3ML

    11931.00per tablet
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Alcohol

Unsafe

It is unsafe to consume alcohol while using DOCETRUST 120MG INJECTION 3ML since it may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Unsafe

It is unsafe to use DOCETRUST 120MG INJECTION 3ML in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using DOCETRUST 120MG INJECTION 3ML.

bannner image

Breast Feeding

Unsafe

DOCETRUST 120MG INJECTION 3ML is not recommended during breastfeeding since it may be unsafe for the breastfed infant. Please seek medical advice if you are a nursing mother before starting DOCETRUST 120MG INJECTION 3ML.

bannner image

Driving

Unsafe

DOCETRUST 120MG INJECTION 3ML causes dizziness and drowsiness that may affect your ability to drive. Do not drive or operate machinery if you experience unmanageable side effects with DOCETRUST 120MG INJECTION 3ML.

bannner image

Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment. Before being treated with DOCETRUST 120MG INJECTION 3ML, your doctor may advise you of blood tests to check your liver functioning.

bannner image

Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting DOCETRUST 120MG INJECTION 3ML.

bannner image

Children

Unsafe

Safety and efficacy of DOCETRUST 120MG INJECTION 3ML have not been established in patients younger than 18 years.

FAQs

DOCETRUST 120MG INJECTION 3ML belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers.
DOCETRUST 120MG INJECTION 3ML contains Docetaxel, an anti-neoplastic agent. It prevents the cancer cells from rapidly dividing and spreading, thus slowing down their growth.
DOCETRUST 120MG INJECTION 3ML should be used with caution and under doctor's supervision only if you have any medical history of any allergic reactions, liver or kidney diseases, non-small cell lung cancer, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions (excess fluid around lungs), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Let your doctor know if you have any other medical concerns before using DOCETRUST 120MG INJECTION 3ML.
During treatment with DOCETRUST 120MG INJECTION 3ML, it is essential to look for any signs of swelling (fluid retention/oedema), dizziness/fainting, difficulty in breathing, irregular heartbeat, swelling, pain and tenderness in the abdomen region, blood in stools, skin rashes, easy bleeding or bruising, sores in the mouth or throat or symptoms of infection like fever and sore throat. If you further notice any symptoms that are not manageable or unusual, please seek prompt medical attention.
It is advised to consult your doctor before undergoing any vaccination and take advice accordingly. Also, please avoid contact with people who have recently been vaccinated with the oral polio vaccine.
DOCETRUST 120MG INJECTION 3ML might cause serious allergic reactions and fluid retention if you had previously experienced allergic reactions with paclitaxel and cabazitaxel. These medicines contain polysorbate 80, an excipient. If you had any allergic reactions with medicines containing polysorbate 80, DOCETRUST 120MG INJECTION 3ML is not recommended. Please consult your doctor for more information.
DOCETRUST 120MG INJECTION 3ML is administered through an intravenous (IV) infusion. A healthcare professional usually gives it in a medical facility.
DOCETRUST 120MG INJECTION 3ML may cause weight loss due to common side effects such as loss of appetite, nausea, vomiting, diarrhoea, and fatigue. But, in rare cases, some patients may experience fluid retention or increased hunger, which can lead to weight gain. Consult your doctor or pharmacist for personalized guidance if you have concerns about weight changes.
The duration of DOCETRUST 120MG INJECTION 3ML treatment varies depending on the type of your cancer, dose of DOCETRUST 120MG INJECTION 3ML, and your response to therapy. Typically, it is administered once every 3 weeks. Your doctor will determine the total length of treatment for you based on your specific situation.
No, it is advisable not to drink alcohol while taking DOCETRUST 120MG INJECTION 3ML. Drinking alcohol during treatment may cause increased dizziness and drowsiness.
No, DOCETRUST 120MG INJECTION 3ML is not available in pill form. It is available in two primary dosage forms: injection and powder for injection.
Before administering DOCETRUST 120MG INJECTION 3ML, certain blood tests are required to ensure safe administration. These tests include a Complete Blood Count (CBC) to check blood cell counts, blood urea nitrogen (BUN) and creatinine levels to assess kidney function, liver function tests (LFTs) to evaluate liver health, and electrolyte level checks. Additionally, other tests may be required depending on individual patient needs and medical history. These blood tests help healthcare providers assess kidney and liver function and other vital parameters to ensure that DOCETRUST 120MG INJECTION 3ML can be administered safely and effectively. Your healthcare provider will determine the necessary blood tests and monitoring requirements.
Hair loss caused by DOCETRUST 120MG INJECTION 3ML is often reversible. While DOCETRUST 120MG INJECTION 3ML can cause hair thinning or loss, hair growth returns once treatment is stopped. However, in some cases, hair loss may be permanent. Consult your healthcare provider for guidance and support if you're concerned about hair loss.
Dexamethasone is used with DOCETRUST 120MG INJECTION 3ML to avoid toxicities.
DOCETRUST 120MG INJECTION 3ML is a chemotherapy medication that belongs to the class of drugs known as anti-neoplastic/anticancer drugs. It is a cytotoxic agent that prevents the cancer cells from rapidly dividing and spreading.
DOCETRUST 120MG INJECTION 3ML causes dizziness and drowsiness that may affect your ability to drive. So, do not drive or operate machinery if you experience these.
The common side effects of DOCETRUST 120MG INJECTION 3ML may include vomiting, constipation, changes in taste, extreme tiredness, muscle, joint, or bone pain, hair loss, nail changes, increased eye tearing, sores in the mouth and throat, and redness, dryness, or swelling at the injection site. However, these symptoms usually diminish as your body adjusts to the medication. If these symptoms worsen, please consult a doctor for relief.
DOCETRUST 120MG INJECTION 3ML is generally considered safe when following your doctor's advice. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
DOCETRUST 120MG INJECTION 3ML contains Docetaxel, which belongs to the anticancer drugs.
Safety and efficacy of DOCETRUST 120MG INJECTION 3ML have not been established in patients younger than 18 years.

Country of origin

India

Manufacturer/Marketer address

Ambala- Chandigarh Highway, Lalru – 140501, Punjab
Other Info - DOC0007

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