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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:17 PM IST
Distoside Tablet is used to treat parasitic infections such as Schistosoma and liver fluke. It contains Praziquantel which works by paralysing the worms. This causes the worms to release their hold on the blood vessels so they can be removed from the body. In some cases, this medicine may cause side effects such as headache, dizziness, abdominal discomfort, nausea, and fever.
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Manufacturer/Marketer

Chandra Bhagat Pharma Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Distoside Tablet

Distoside Tablet belongs to the class of medicines called anthelmintics used to treat infections due to Schistosoma and liver fluke. Schistosomiasis, also known as snail fever, Katayama fever, and bilharzia, is a disease caused by infection with freshwater parasitic flatworms called schistosomes. Liver fluke infection is caused by parasitic worms called liver flukes after eating contaminated raw or uncooked watercress or freshwater fish.
 
Distoside Tablet contains ‘Praziquantel’, which kills the parasites by paralysing the worms. This causes the worms to release their hold on the blood vessels. It also stops the parasite from absorbing sugars. The parasite then disintegrates with the help of white blood cells and passes out of the body. Thereby, Distoside Tablet helps treat schistosomiasis and liver fluke infections.
 
You are advised to take Distoside Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience side effects such as headache, dizziness, abdominal discomfort, nausea, and fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Avoid driving or operating machinery on the day of treatment and the following day, as Distoside Tablet may cause dizziness. Consult your doctor if you are pregnant, planning for pregnancy, or think you are pregnant. Avoid breastfeeding whilst taking Distoside Tablet and during the subsequent 72 hours/3 days. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Distoside Tablet

Treatment of Schistosomiasis and liver fluke infection

Medicinal Benefits

Distoside Tablet belongs to the class of medicines called anthelmintics used to treat infections due to Schistosoma and liver fluke. Distoside Tablet kills the parasites by paralysing the worms. This causes the worms to release their hold on the blood vessels so they can be removed from the body. Thereby, Distoside Tablet helps treat schistosomiasis and liver fluke infections. Distoside Tablet may also be used to treat other worm infections, including tapeworm infection.

Directions for Use

Take Distoside Tablet with food. Swallow Distoside Tablet as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Distoside Tablet

  • Headache
  • Dizziness
  • Abdominal discomfort
  • Nausea
  • Fever

Drug Warnings

Do not take Distoside Tablet if you are allergic to any of its components, if you are taking rifampicin (a medicine used to treat tuberculosis), dexamethasone (corticosteroid), and antiepileptic medicines. Avoid taking Distoside Tablet if you have parasitic eye infections. Inform your doctor if you have heart problems, epilepsy, skin nodules, kidney or liver problems. Consult your doctor if you are pregnant, planning for pregnancy, or think you are pregnant. Avoid breastfeeding whilst taking Distoside Tablet and during the subsequent 72 hours/3 days. Safety of Distoside Tablet in children below 4 years has not been established; consult a doctor if you have any concerns. Avoid driving or operating machinery on the day of treatment and the following day, as Distoside Tablet may cause dizziness.

Drug Interactions

Drug-Drug Interactions: Distoside Tablet may interact with antibiotic (rifampicin, erythromycin), corticosteroid (dexamethasone), antacid (cimetidine), antimalarial (chloroquine), antifungal (ketoconazole, itraconazole), and antiepileptic medicines.

Drug-Food Interactions: Grapefruit may interact with Distoside Tablet leading to unwanted side effects. Therefore, avoid consumption of grapefruit or grapefruit juice while taking Distoside Tablet.

Drug-Disease Interactions: Inform your doctor if you have parasitic eye infections, seizures, arrhythmia, or liver impairment.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • ERYTHROMYCIN
  • DEXAMETHASONE
  • CIMETIDINE
  • CHLOROQUINE
  • KETOCONAZOLE
  • ITRACONAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Always eat thoroughly cooked fish and meat.
  • Avoid consuming contaminated food and water.
  • Include iron-rich foods, such as leafy vegetables, legumes, and fortified foods.
  • Avoid raw or uncooked meat.
  • Drink boiled and purified water.
  • Avoid consuming foods kept in open markets as they might be contaminated.
  • Wash or reheat food that has been around for a long time.
  • Always wash fruits and vegetables thoroughly with fresh water before consumption.

Disease/Condition Glossary

Schistosomiasis: Schistosomiasis, also known as snail fever, Katayama fever, and bilharzia, is a disease caused by infection with freshwater parasitic flatworms called schistosomes. The parasites in the contaminated water penetrate human skin to enter into the bloodstream and migrate to various organs leading to infections. Symptoms include diarrhoea, bloody stools, blood in the urine, abdominal pain, joint pain, muscle pain, headache, cough, chills, fever, itchy skin, and rash.

Liver fluke infection: This infection is caused by parasitic worms called liver flukes after eating contaminated raw or uncooked watercress or freshwater fish. After ingestion, the liver flukes travel from the intestine to the bile ducts in the liver, where they live and grow. Symptoms include fever, nausea, vomiting, diarrhoea, abdominal pain, weakness, loss of appetite, and hives.

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Alcohol

Caution

Avoid alcohol consumption as it might cause increased dizziness.

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Pregnancy

Caution

Distoside Tablet belongs to pregnancy category B. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if clearly needed.

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Breast Feeding

Unsafe

Distoside Tablet may pass into breastmilk. Avoid breastfeeding whilst taking Distoside Tablet and during the subsequent 72 hours/3 days.

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Driving

Unsafe

Distoside Tablet may cause dizziness. Avoid driving or operating machinery on the day of treatment and the following day.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Distoside Tablet in patients with liver impairment. Distoside Tablet should be used with caution in patients with moderate to severe liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Distoside Tablet in patients with kidney impairment.

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Children

Caution

Safety of Distoside Tablet in children below 4years has not been established.

Country of origin

INDIA

Manufacturer/Marketer address

501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai - 400071
Other Info - DIS0049

Author Details

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FAQs

Distoside Tablet is used to treat parasitic infections, including Schistosomiasis and liver fluke infection.
Distoside Tablet kills the parasites by paralysing the worms. This causes the worms to release their hold on the blood vessels so that they can be removed from the body. Thereby, Distoside Tablet helps treat schistosomiasis and liver fluke infections.
To treat your infection effectually, continue taking Distoside Tablet for as long as it has been prescribed by the doctor. Do not be reluctant to speak with the doctor if you experience any difficulty while taking Distoside Tablet.
Concomitant administration of Distoside Tablet with rifampin is not recommended as therapeutically effective blood levels of Distoside Tablet may not be achieved when taken together. Consult your doctor if you are taking rifampin; your doctor may prescribe alternate medicine. However, if treatment with Distoside Tablet is necessary, rifampin should be discontinued 4 weeks before starting Distoside Tablet. Rifampin can be restarted one day after the completion of treatment with Distoside Tablet.
Distoside Tablet is unlikely to cause diarrhoea. Eat non-spicy food and drink plenty of fluids if you experience diarrhoea. If you notice bloody diarrhoea, consult your doctor immediately.
Avoid taking Distoside Tablet if you have parasitic eye infections, as killing the parasite might cause blindness. Talk to your doctor if you have any concerns regarding this.
Yes. Distoside Tablet is effective treatment for Schistosomiasis infections (Infection with the type of worm that lives in the bloodstream) and Liver fluke infections (Infection with a type of worm that lives in or nearer the liver), when it is taken as directed by the physician.
Yes. Distoside Tablet may cause dizziness in some cases. Do not drive a vehicle or do anything that requires mental focus until you feel normal.
Do not take Distoside Tablet if you are allergic to any of its ingredients, have a parasitic eye infection, or are pregnant. Additionally, breastfeeding should be avoided while taking Distoside Tablet and for 3 days after finishing the medication. It's also important to note that Distoside Tablet has not been proven safe for children under 4 years old, so be sure to consult a doctor before giving it to your child.
Store Distoside Tablet in its original container, tightly closed. Follow the storage instructions on the label. Dispose of any unused medicine safely. Keep out of reach of children, pets, and others to avoid accidental consumption.
Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Distoside Tablet is safe when used correctly, but like all medicines, it can have some side effects. To ensure safe use, it's important to talk to a healthcare professional before taking it. They will provide guidance and instructions on how to use Distoside Tablet effectively. By following their advice, you can minimize the risk of side effects and use the medication safely.
The common side effects of Distoside Tablet may include headache, dizziness, abdominal discomfort, nausea, and fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

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