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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 13, 2024 | 12:53 PM IST

DIRIFA 200MG TABLET is used to treat infectious traveller's diarrhoea caused by E.coli bacteria, hepatic encephalopathy (decreased brain function due to liver disease) and irritable bowel syndrome with diarrhoea (IBS-D). It contains Rifaximin, which works by working on the bowel and preventing the spread of infections caused by the loss of beneficial gut bacteria. Thus, it helps in relieving abdominal pain and diarrhoea. In some cases, you may experience certain common side effects such as headache, peripheral oedema (leg swelling), nausea, dizziness, fatigue, ascites (excess fluid build-up in the abdomen), increased liver enzymes (ALT), and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

RIFAXIMIN-200MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About DIRIFA 200MG TABLET

DIRIFA 200MG TABLET used to treat infectious traveller's diarrhoea caused by E.coli bacteria, hepatic encephalopathy (decreased brain function due to liver disease) and irritable bowel syndrome with diarrhoea (IBS-D). Traveller’s diarrhoea is an infection in which there is a passage of unformed stools. Hepatic encephalopathy causes loss of brain function when a damaged liver is unable to remove toxins from the blood. Irritable bowel syndrome is a condition which affects the large intestine. 

DIRIFA 200MG TABLET contains ‘Rifaximin’, which works by working on the bowel and preventing the spread of infections caused by the loss of beneficial gut bacteria.  Thus, DIRIFA 200MG TABLET helps in relieving abdominal pain and diarrhoea. DIRIFA 200MG TABLET should not be used in patients with diarrhoea complicated by fever or blood in the stool and diarrhoea due to pathogens other than Escherichia coli (E.coli).

Take DIRIFA 200MG TABLET with or without food. In some cases, you may experience certain common side effects such as headache, peripheral oedema (leg swelling), nausea, dizziness, fatigue, ascites (excess fluid build-up in the abdomen), increased liver enzymes (ALT), and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting DIRIFA 200MG TABLET , please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take DIRIFA 200MG TABLET for more than 3 days unless prescribed; if there is no symptomatic improvement, consult your doctor. Avoid taking DIRIFA 200MG TABLET if you are pregnant or breastfeeding; talk to your doctor; he/she may prescribe you alternate medicine. DIRIFA 200MG TABLET is not recommended for children as efficacy and safety have not been established. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.

Uses of DIRIFA 200MG TABLET

Treatment of travelles diarrhoea, liver encephalopathy, and irritable bowel syndrome due to diarrhoea.

Medicinal Benefits

DIRIFA 200MG TABLET belongs to the group of medicines called antibiotics used to treat infectious travellers diarrhoea, hepatic encephalopathy (decrease in brain function due to liver disease) and irritable bowel syndrome (IBS). DIRIFA 200MG TABLET is used to treat traveller’s diarrhoea caused by non-invasive strains of E.coli. DIRIFA 200MG TABLET is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and anaerobic bacteria, and ammonia-producing bacteria. DIRIFA 200MG TABLET is a gastrointestinal-selective antibiotic with a broad spectrum of antimicrobial activity. DIRIFA 200MG TABLET is bactericidal in nature and works by killing the bacteria that cause infections. Thus, it helps in treating and preventing the spread of infections.

Side Effects of DIRIFA 200MG TABLET

  • Headache
  • Peripheral oedema (leg swelling)
  • Nausea
  • Dizziness
  • Fatigue
  • Ascites (excess fluid build-up in the abdomen)
  • Increased liver enzymes (ALT)

Directions for Use

Swallow the medicine as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take DIRIFA 200MG TABLET if you are allergic to any of its contents, if you have a fever, blood in stools, passed 8 or more unformed stools in the last 24 hours, constipation, vomiting, and abdominal pain caused by blockage of the bowel. Talk to your doctor if your condition does not improve, symptoms continue or re-appear even after taking DIRIFA 200MG TABLET for 3 days. Do not take DIRIFA 200MG TABLET for more than 3 days unless prescribed; if there is no symptomatic improvement, consult your doctor. Avoid taking DIRIFA 200MG TABLET if you are pregnant or breastfeeding; talk to your doctor; he/she may prescribe you with alternate medicine. DIRIFA 200MG TABLET is not recommended for children below 12 years of age as the efficacy and safety have not been established. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects. Patients with liver complications should avoid taking DIRIFA 200MG TABLET or consult a doctor before using DIRIFA 200MG TABLET .

Therapeutic Class

ANTIBIOTICS

Drug-Drug Interactions

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RifaximinCholera, live attenuated
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which helps indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, such as grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol to treat your condition effectively.
  • Avoid the usage of tobacco.

Habit Forming

No

What if I have taken an overdose of DIRIFA 200MG TABLET

Do not take more than the prescribed dose of DIRIFA 200MG TABLET as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Caution

Please consult your doctor as it is not known whether alcohol affects the working of DIRIFA 200MG TABLET . However, you are advised to limit or avoid alcohol consumption to prevent unpleasant side-effects.

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Pregnancy

Caution

It is not recommended to take DIRIFA 200MG TABLET while you are pregnant. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether DIRIFA 200MG TABLET can be given to pregnant women or not.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will decide whether DIRIFA 200MG TABLET can be given to breastfeeding mothers or not.

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Driving

Safe if prescribed

DIRIFA 200MG TABLET does not affect your ability to drive. However, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Please consult your doctor if you have any concerns regarding this or if you have liver impairment/liver disease before taking DIRIFA 200MG TABLET .

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Kidney

Caution

Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking DIRIFA 200MG TABLET .

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Children

Unsafe

DIRIFA 200MG TABLET is not recommended for children as the efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - DIR0027

Author Details

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FAQs

DIRIFA 200MG TABLET is used to treat infectious traveller's diarrhoea caused by E.coli bacteria, hepatic encephalopathy (decreased brain function due to liver disease) and irritable bowel syndrome with diarrhoea (IBS-D).
DIRIFA 200MG TABLET is bactericidal in nature and works by killing the harmful bacteria that cause infections in the gut or intestine like E coli bacteria. Thereby, helps in treating/preventing the spread of infections and diarrhoea with abdominal pain.
It is recommended to complete the course of DIRIFA 200MG TABLET even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).
Do not take DIRIFA 200MG TABLET on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Take DIRIFA 200MG TABLET only if prescribed by a doctor.
DIRIFA 200MG TABLET may affect blood tests and liver function tests with increased liver enzymes. Inform the person or doctor before performing the tests that you are taking DIRIFA 200MG TABLET .
For treating traveller's diarrhoea, DIRIFA 200MG TABLET is generally prescribed for 3 days. For irritable bowel syndrome, DIRIFA 200MG TABLET is prescribed for 14 days. However, it is better to take DIRIFA 200MG TABLET only as prescribed by your doctor.
No, DIRIFA 200MG TABLET may affect the activity and working of warfarin when taken together. So tell your doctor before using DIRIFA 200MG TABLET that you are taking a blood thinner (warfarin). Your doctor might adjust the dose of warfarin to maintain the proper blood-thinning effect and prevent drug interaction.
Do not take DIRIFA 200MG TABLET for more than 3 days unless prescribed; if there is no symptomatic improvement, consult your doctor.
DIRIFA 200MG TABLET should not be used in patients with diarrhoea complicated by fever or blood in the stool and diarrhoea due to pathogens other than Escherichia coli (E. coli).
Take DIRIFA 200MG TABLET exactly as prescribed by the doctor. Take it at the same time daily as it will help you to remember taking the medication.
DIRIFA 200MG TABLET contains Rifaximin used to treat infectious traveller’s diarrhoea, hepatic encephalopathy (decrease in brain function due to liver disease) and irritable bowel syndrome.
Side effects of DIRIFA 200MG TABLET include headache, peripheral oedema (leg swelling), nausea, dizziness, fatigue, ascites (excess fluid build-up in the abdomen), increased liver enzymes (ALT), and nausea. Talk to your doctor if you experience these side effects persistently.
DIRIFA 200MG TABLET is an antimycobacterial which works by killing the bacteria that cause infection.
DIRIFA 200MG TABLET can be taken with or without food.
DIRIFA 200MG TABLET decreases the symptoms in case of liver disease by killing harmful bacteria in the gut. Thereby it helps lower the possibility of toxins.
DIRIFA 200MG TABLET may not cause weight gain. Maintain proper weight by eating healthy and doing exercise. Consult the doctor if you notice changes in your weight.

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