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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:48 PM IST
Dirab 5 mg Tablet is used to treat gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. It contains Dexrabeprazole which reduces the amount of acid produced by the stomach and prevents acid reflux. In some cases, this medicine may cause side effects such as diarrhoea, nausea, vomiting, headache, dizziness, stomach pain or constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Hetero Drugs Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Dirab 5 mg Tablet

aDirab 5 mg Tablet belongs to a class of drugs called 'proton pump inhibitors' used to treat gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. Zollinger-Ellison syndrome is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production.

Dirab 5 mg Tablet contains 'Dexrabeprazole' that works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, Dirab 5 mg Tablet reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, it provides relief from heartburn symptoms related to acid reflux.

Take Dirab 5 mg Tablet as prescribed by your doctor. You are advised to take Dirab 5 mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhoea, nausea, vomiting, headache, dizziness, stomach pain or constipation. Most of these side effects of Dirab 5 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Dirab 5 mg Tablet or any other medicines, please tell your doctor. Dirab 5 mg Tablet is not recommended for children as safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before taking Dirab 5 mg Tablet . Drive only if you are alert as Dirab 5 mg Tablet may cause drowsiness. Avoid alcohol consumption as it may lead to increased production of stomach acid, thereby increasing acidity and heartburn. Inform your doctor if you have any risk factors for reduced vitamin B12 as Dirab 5 mg Tablet may reduce the absorption of vitamin B12. If you get any skin rash, particularly in areas exposed to sun or pain in joints, inform your doctor.

Uses of Dirab 5 mg Tablet

Treatment of Gastroesophageal reflux disease (GERD), Peptic ulcers and Zollinger-Ellison syndrome.

Medicinal Benefits

Dirab 5 mg Tablet contains Dexrabeprazole used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Dirab 5 mg Tablet blocks the action of proton pumps that are involved in producing stomach acid. Thereby, Dirab 5 mg Tablet reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, it provides relief from heartburn symptoms related to acid reflux. Also, Dirab 5 mg Tablet may be used in combination with clarithromycin and amoxicillin (antibiotics) to eradicate Helicobacter pylori (a type of bacteria) from the stomach in patients with peptic ulcers.

Directions for Use

Take Dirab 5 mg Tablet on an empty stomach or as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dirab 5 mg Tablet

  • Diarrhoea
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Stomach pain
  • Constipation

Drug Warnings

If you are allergic to Dirab 5 mg Tablet or any other medicines, please tell your doctor. Dirab 5 mg Tablet is not recommended for children as safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before taking Dirab 5 mg Tablet . If you have a stomach tumor, liver problems, low magnesium levels in the blood, osteoporosis (weak and brittle bones), or lupus (an autoimmune disorder), inform your doctor before taking Dirab 5 mg Tablet . Inform your doctor if you have any risk factors for reduced vitamin B12 as Dirab 5 mg Tablet may reduce the absorption of vitamin B12. If you get any skin rash, particularly in areas exposed to sun or pain in joints, inform your doctor. If you are taking Dirab 5 mg Tablet for more than 1 year, it may increase the risk of fracture of the spine, hip, or wrist. Drive only if you are alert as Dirab 5 mg Tablet may cause drowsiness. Avoid alcohol consumption as it may lead to increased production of stomach acid, thereby increasing acidity and heartburn. Dirab 5 mg Tablet may decrease magnesium levels in the blood, especially if taken for more than 3 months. Therefore, regular blood tests are recommended to monitor magnesium levels. If you experience bloody or watery diarrhea with symptoms such as stomach pain, fever, or tenderness, contact your doctor immediately.

Drug Interactions

Drug-Drug Interaction: Dirab 5 mg Tablet may interact with anti-HIV drug (atazanavir), antifungals (ketoconazole, itraconazole), anticancer drug (methotrexate), heart-related medicine (digoxin), blood thinner (warfarin).

Drug-Food Interaction: Dirab 5 mg Tablet may interact with St. John’s wort (herbal supplement used to treat depression). Avoid alcohol consumption as alcohol intake leads to increased production of stomach acid, thereby irritating the stomach lining and worsening the symptoms.

Drug-Disease Interaction: If you have a stomach tumor, liver problems, low magnesium levels in the blood, osteoporosis (weak and brittle bones), or lupus (an autoimmune disorder), inform your doctor before taking Dirab 5 mg Tablet .

Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE
  • METHOTREXATE
  • DIGOXIN
  • WARFARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Special Advise

  • Regular blood tests are recommended while taking Dirab 5 mg Tablet to monitor magnesium levels in the blood.
  • Dirab 5 mg Tablet may cause some abnormal liver enzyme and blood values. These changes are temporary and may return to normal after treatment with Dirab 5 mg Tablet is discontinued.

Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets irritated or eroded, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (esophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste in the mouth, and difficulty swallowing.

Peptic ulcers: These are sores that develop on the lining of the stomach and intestine due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Zollinger-Ellison syndrome: It is characterized by the formation of tumors in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.

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Alcohol

Unsafe

Avoid alcohol consumption as it may lead to increased production of stomach acid, thereby irritates the stomach lining and worsen the symptoms.

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Pregnancy

Caution

Dirab 5 mg Tablet is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Dirab 5 mg Tablet is usually contraindicated in breastfeeding mothers. Therefore, please consult a doctor before taking Dirab 5 mg Tablet if you are breastfeeding.

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Driving

Caution

Dirab 5 mg Tablet may cause drowsiness in some people. Therefore, avoid driving or operating machinery if you feel drowsy after taking Dirab 5 mg Tablet .

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Liver

Caution

Take Dirab 5 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Dirab 5 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Dirab 5 mg Tablet is not recommended for children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - DIR0011

Author Details

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FAQs

Dirab 5 mg Tablet is used to treat gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome.
Dirab 5 mg Tablet contains Dexrabeprazole that works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, Dirab 5 mg Tablet reduces the amount of acid produced by stomach and prevents excess acid flowing back into foodpipe. Thus, provides relief from heartburn symptoms related to acid reflux.
Dirab 5 mg Tablet may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery or bloody stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Dirab 5 mg Tablet to prevent dehydration.
Dirab 5 mg Tablet may cause low levels of magnesium in the blood if taken for more than 3 months. If you experience involuntary muscle contractions, tiredness, fits, increased heart rate or dizziness while taking Dirab 5 mg Tablet , please consult a doctor immediately as these might be signs of low magnesium levels. However, regular blood tests are recommended to monitor magnesium levels in the blood while taking Dirab 5 mg Tablet .
You are not recommended to take Dirab 5 mg Tablet with antifungals such as ketoconazole or itraconazole as it may reduce the effectiveness of antifungal against fungal infections. However, please consult your doctor before taking Dirab 5 mg Tablet with other medicines.
Dirab 5 mg Tablet should be used with caution in osteoporosis (weak and brittle bones) patients as it may worsen the condition especially if Dirab 5 mg Tablet is taken for more than 1 year as it increases the risk of fracture of spine, hip or wrist. Therefore, inform your doctor if have osteoporosis or if you are taking any steroids which may increase the risk of osteoporosis.
Dirab 5 mg Tablet may reduce the absorption of vitamin B12 and lead to its deficiency if used for more than 3 years. Therefore, inform your doctor if you have any risk factors for reduced vitamin B12 before taking Dirab 5 mg Tablet .
Dirab 5 mg Tablet is generally safe when used for the duration prescribed by your doctor. However, using it for more than a year or longer may increase the risk of side effects, such as bone fractures, low magnesium levels, vitamin B12 deficiency, and fundic gland polyps (growths in your stomach lining).
Long-term use of Dirab 5 mg Tablet may lead to nutrient deficiencies, particularly in magnesium, calcium, and vitamin B12, due to reduced absorption. This may also increase the risk of bone fractures because of lower calcium levels. Therefore, it is important to follow your doctor's instructions when using Dirab 5 mg Tablet , especially for extended periods.
It is generally not recommended to drink alcohol while taking Dirab 5 mg Tablet , as alcohol can irritate your stomach lining and may reduce the effectiveness of the medication in treating acid-related conditions.
Yes, you can take Dirab 5 mg Tablet (a proton pump inhibitor) with antacids if your doctor advises it. Dirab 5 mg Tablet works best when your stomach is less acidic, and antacids can change the acidity in your stomach. To avoid any possible interference, it is advisable to maintain a gap of 2 hours between Dirab 5 mg Tablet and antacid medicines.
It is important to follow your doctor's advice about when to stop taking Dirab 5 mg Tablet . Even if symptoms have improved, stopping the medication too soon may cause symptoms to return.
Dirab 5 mg Tablet usually starts working within an hour of taking it. You may begin to feel better within 2 to 3 days, but it can take up to 4 weeks for your symptoms to fully improve.
The common side effects of Dirab 5 mg Tablet include diarrhoea, nausea, vomiting, headache, dizziness, stomach pain, and constipation. Most of these side effects of Dirab 5 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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