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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Diprobate G Plus Cream is used to treat bacterial skin infections. It works by killing infection-causing bacteria and inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. In some cases, this medicine may cause side effects such as peeling of the skin, acne, changes in skin colour, and dry skin. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Consume Type

TOPICAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Diprobate G Plus Cream

Diprobate G Plus Cream is used to treat various bacterial skin infections. Bacterial skin infections include eczema (inflamed, itchy, cracked, and rough skin patches), psoriasis (uneven or bumpy red patches covered with white scales), and dermatitis (itchy inflammation of the skin). A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection.

Diprobate G Plus Cream is a combination of three drugs: Zinc (antiseptic), Betamethasone (corticosteroid), and Gentamicin (antibiotic). Betamethasone blocks prostaglandin production (chemical messengers), making the affected area red, swollen, and itchy. Gentamicin prevents the synthesis of essential proteins required by the bacteria to carry out vital functions. Zinc acts as an antiseptic (prevents microbe's growth) and astringent (contracts the skin cells) on the skin.

You are advised to use Diprobate G Plus Cream for as long as your doctor has prescribed it for you, depending on your medical condition. You may experience peeling of the skin, drying and cracking of the skin, acne, change in skin colour, dry skin, itching, irritation, or burning sensation at the application site. Most of these side effects of Diprobate G Plus Cream do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use Diprobate G Plus Cream if you are allergic to any of its ingredients. Do not cover or wrap the treated area with bandages unless advised by your doctor. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Diprobate G Plus Cream catches fire and burns easily, which is a serious fire hazard. If you are pregnant or breastfeeding, please inform your doctor before using Diprobate G Plus Cream.

Uses of Diprobate G Plus Cream

Treatment of Bacterial skin infections

Medicinal Benefits

Diprobate G Plus Cream is a combination of three drugs: Zinc, Betamethasone, and Gentamicin, which reduces swelling, itching, and redness caused by bacterial skin infections. Betamethasone is a corticosteroid and blocks prostaglandin's production (chemical messengers), which makes the affected area red, swollen, and itchy. Betamethasone effectively treats inflammation and itchiness. Gentamicin is an aminoglycoside antibiotic that prevents bacteria from synthesising essential proteins required by bacteria to carry out vital functions. Zinc acts as an antiseptic (prevents microbe's growth) and astringent (contracts the skin cells) on the skin. Diprobate G Plus Cream used to treat various bacterial skin infections, such as eczema (inflamed, itchy, cracked, and rough skin patches), psoriasis (skin cells multiply rapidly to form bumpy (uneven) red patches covered with white scales), dermatitis (itchy inflammation of the skin).

Directions for Use

Wash your hands before and after applying Diprobate G Plus Cream. Take a small amount of Diprobate G Plus Cream and gently apply as a thin layer on the skin's affected area as prescribed by your doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Diprobate G Plus Cream

  • Peeling of skin
  • Drying and cracking of the skin
  • Acne
  • Change in skin colour
  • Dry skin
  • Itching
  • Irritation
  • Burning sensation at the application site

Drug Warnings

Do not use Diprobate G Plus Cream if you are allergic to any of its components. If you are pregnant or breastfeeding, please inform your doctor. Do not use Diprobate G Plus Cream on children unless prescribed by the doctor. Do not wrap or cover the treated area with bandages unless advised by your doctor, as it may increase the risk of side effects. Do not use Diprobate G Plus Cream in more than prescribed doses or on a large area of skin for a longer duration, as it may cause side effects and makes skin more sensitive to Diprobate G Plus Cream. Do not swallow Diprobate G Plus Cream. In case of accidental swallowing, please consult a doctor. Do not apply Diprobate G Plus Cream (skin cream) in the eye as it may lead to glaucoma or cataract. Please consult a doctor if you experience blurred vision or other vision disturbances.  Keep your doctor informed about all the medicines you are taking and your health condition to rule out any side effects. If you have acne, perioral dermatitis (redness and swelling of the skin around the mouth), rosacea (redness and often red, small, pus-filled bumps on the face), glaucoma, cataracts, ear or eye infections due to fungus, a hole in the eardrum, syphilis (a bacterial infection), chickenpox or sores, athlete’s foot, broken veins or skin ulcers, tuberculosis, please inform your doctor.

Drug Interactions

Drug-Drug Interaction: Diprobate G Plus Cream may interact with medicines used for preventing pregnancy (mifepristone), antidiabetic drugs (metformin, pioglitazone, acarbose, glimepiride), antibiotics (azithromycin, rifampicin), antianxiety (phenobarbitone), medicines used to treat eczema (tacrolimus), medicines for skin disease (bacitracin), medicines for tuberculosis (Capreomycin), antifungal (clotrimazole), water pills (furosemide).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have rosacea (red, small, pus-filled bumps on the face), acne, perioral dermatitis (redness and swelling of the skin around the mouth), diabetes, tuberculosis, syphilis (a bacterial infection), chickenpox or sores, broken veins or skin ulcers, please inform your doctor before using Diprobate G Plus Cream.

Drug-Drug Interactions Checker List

  • MIFEPRESTONE
  • METFORMIN
  • PIOGLITAZONE
  • ACARBOSE
  • GLIMEPIRIDE
  • AZITHROMYCIN
  • RIFAMPICIN
  • PHENOBARBITAL
  • TACROLIMUS
  • BACITRACIN
  • CAPREOMYCIN
  • CLOTRIMAZOLE
  • FUROSEMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach, and blueberries.

  • Consuming food rich in probiotics helps in developing the immune system against allergies.

  • Limit food intake that might trigger allergies, such as dairy products, soy, eggs, and nuts.

  • Avoid the consumption of foods with excess sugar, as it may flare up inflammation.

  • Include fruits, vegetables, whole grains, healthy fats, and fish.

Special Advise

  • Please consult a dermatologist if the symptoms persist or worsen after using Diprobate G Plus Cream for one month.

  • Do not use Diprobate G Plus Cream on dressing, band-aids, and make-up unless told by the doctor.

Disease/Condition Glossary

Bacterial skin infection: This is a skin condition in which the immune system becomes triggered and disordered, causing inflammation, dry skin, itching, and a skin rash that appears purple or grey or red in colour.

Eczema: It is caused due to change in the gene, which forms filaggrin (protein). This protein gets damaged due to the bacterial infection damaging the skin barrier, allowing bacteria to cause dry, itchy, and allergic skin.

Psoriasis: It is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. 

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Alcohol

Consult your doctor

The interaction of Diprobate G Plus Cream with alcohol is unknown. Please consult a doctor before consuming alcohol while using Diprobate G Plus Cream.

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Diprobate G Plus Cream is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Do not apply Diprobate G Plus Cream on the breast area. Diprobate G Plus Cream is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Consult your doctor

It is unknown if Diprobate G Plus Cream affects your ability to drive. Please consult a doctor.

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Liver

Consult your doctor

If you have any concerns regarding the use of Diprobate G Plus Cream in patients with Liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Diprobate G Plus Cream in patients with Kidney problems, please consult a doctor.

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Children

Caution

Diprobate G Plus Cream should be used with caution in children if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - DIP0191

Author Details

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FAQs

Diprobate G Plus Cream is used to treat bacterial skin infections.
Diprobate G Plus Cream contains Betamethasone, Gentamicin, and Zinc. Betamethasone inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. Gentamicin inhibits the production of essential proteins necessary for bacteria to grow, multiply, and increase in numbers. Thereby, it stops the growth of bacteria without killing them directly. Zinc acts as an antiseptic (prevents microbe's growth) and astringent (contracts the skin cells) on the skin.
You are recommended to cover the treated area of the skin with bandages or dressings only if advised by your doctor. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.
No, Diprobate G Plus Cream is not used to treat diaper rash. Using Diprobate G Plus Cream under the child’s nappy enables Diprobate G Plus Cream to pass through the skin easily and cause adverse effects. However, please consult a doctor before using Diprobate G Plus Cream in children.
Diprobate G Plus Cream should be used with caution in diabetic patients as Diprobate G Plus Cream contains Betamethasone (corticosteroid). Generally, steroid medicines may increase blood sugar levels. Therefore, inform your doctor if you have diabetes before using Diprobate G Plus Cream.
No, Diprobate G Plus Cream is not recommended to treat acne as it may worsen the condition. Diprobate G Plus Cream is only used to reduce itching, swelling, and redness caused due to certain skin diseases such as psoriasis, eczema, or dermatitis. However, please consult a doctor before using Diprobate G Plus Cream.

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