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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dinogest 2 mg Combipack is used to treat endometriosis. It contains Dienogest which suppresses the production of a hormone (oestradiol) that causes excess growth in the endometrium. In some cases, this medicine may cause side effects such as acne, headache, abdominal pain, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

DIENOGEST-2MG

Manufacturer/Marketer :

Koye Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Dinogest 2 mg Combipack

Dinogest 2 mg Combipack is used for the management of painful symptoms of endometriosis. Endometriosis is a painful disorder in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus. Endometriosis generally involves ovaries, pelvis lining, and fallopian tubes.
 
Dinogest 2 mg Combipack contains ‘Dienogest’, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, Dinogest 2 mg Combipack helps in treating pelvic pain associated with endometriosis.
 
You are advised to take Dinogest 2 mg Combipack as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Dinogest 2 mg Combipack may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Avoid taking Dinogest 2 mg Combipack if you are pregnant, planning for pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking Dinogest 2 mg Combipack . Dinogest 2 mg Combipack should not be given to children who have not had their first period. Dinogest 2 mg Combipack may cause dizziness, so drive with caution. Avoid or limit alcohol consumption, as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Dinogest 2 mg Combipack

Treatment of Endometriosis

Directions for Use

Swallow the medicine as a whole with water; do not chew, break it.

Medicinal Benefits

Dinogest 2 mg Combipack belongs to a group of medicines called progestin indicated for the management of endometriosis. Dinogest 2 mg Combipack suppresses the production of a hormone called estradiol which causes excess growth of the endometrium. Thereby, Dinogest 2 mg Combipack helps in treating pelvic pain associated with endometriosis. Dinogest 2 mg Combipack may also be used in menopausal hormonal therapy and heavy periods.

How Dinogest 2 mg Combipack Works

Dinogest 2 mg Combipack contains ‘Dienogest’, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, Dinogest 2 mg Combipack helps in treating pelvic pain associated with endometriosis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dinogest 2 mg Combipack

  • Acne
  • Headache
  • Depression
  • Breast discomfort
  • Nausea
  • Vomiting
  • Abdominal pain

What if I have taken an overdose of Dinogest 2 mg Combipack

Take Dinogest 2 mg Combipack only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Dinogest 2 mg Combipack if you are allergic to any of its components; if you have a blood clot in the lungs, heart, brain, blood vessels of legs or any part of the body, if you have/had diabetes mellitus with damaged blood vessel, severe liver damage, unexplained vaginal bleeding, and benign or malignant tumour. Talk to your doctor if you have diabetes, high blood pressure, depression, are overweight, have chloasma (yellowish-brown pigmentation on the skin), had an ectopic pregnancy (embryo develops outside the womb), or if you or anyone in your immediate family has had blood clots in lungs/legs, or heart attack, high cholesterol or stroke. Avoid taking Dinogest 2 mg Combipack if you are pregnant, planning for pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking Dinogest 2 mg Combipack . Dinogest 2 mg Combipack should not be given to children who have not had their first period. Dinogest 2 mg Combipack may cause dizziness, so drive with caution.

Drug-Drug Interactions

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DienogestEfavirenz
Critical
DienogestPhenytoin
Severe

Drug-Drug Interactions

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DienogestEfavirenz
Critical
How does the drug interact with Dinogest 2 mg Combipack 10's:
When Efavirenz is taken with Dinogest 2 mg Combipack 10's, it can lower the metabolism of Dinogest 2 mg Combipack 10's and increase the risk or severity of side effects.

How to manage the interaction:
Taking Efavirenz with Dinogest 2 mg Combipack 10's can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
DienogestPhenytoin
Severe
How does the drug interact with Dinogest 2 mg Combipack 10's:
Taking Phenytoin with Dinogest 2 mg Combipack 10's may reduce the blood levels and effects of Dinogest 2 mg Combipack 10's.

How to manage the interaction:
Although taking Phenytoin and Dinogest 2 mg Combipack 10's together can result in an interaction, it can be taken if a doctor has prescribed it. If you use Dinogest 2 mg Combipack 10's as hormone replacement therapy for menopause, let a doctor know if your symptoms stop being controlled by your medication or if you start bleeding abnormally. Do not discontinue any medications without consulting a doctor.
DienogestDantrolene
Severe
How does the drug interact with Dinogest 2 mg Combipack 10's:
Co-administration of Dantrolene with Dinogest 2 mg Combipack 10's can cause serious side effects that may affect your liver.

How to manage the interaction:
Taking Dinogest 2 mg Combipack 10's with Dantrolene together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
DienogestCarbamazepine
Severe
How does the drug interact with Dinogest 2 mg Combipack 10's:
Taking carbamazepine with Dinogest 2 mg Combipack 10's may increase the effect of carbamazepine.

How to manage the interaction:
Although there is a possible interaction, Dinogest 2 mg Combipack 10's can be taken with Carbamazepine if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
DienogestMycophenolic acid
Severe
How does the drug interact with Dinogest 2 mg Combipack 10's:
Co-administration of Dinogest 2 mg Combipack 10's with Mycophenolic acid may decrease the levels and action of Dinogest 2 mg Combipack 10's.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Dinogest 2 mg Combipack 10's, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
DienogestPrimidone
Severe
How does the drug interact with Dinogest 2 mg Combipack 10's:
Taking Dinogest 2 mg Combipack 10's with Primidone may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between primidone and Dinogest 2 mg Combipack 10's, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DienogestBosentan
Severe
How does the drug interact with Dinogest 2 mg Combipack 10's:
Co-administration of Dinogest 2 mg Combipack 10's with Bosentan may decrease the effectiveness of Dinogest 2 mg Combipack 10's.

How to manage the interaction:
Although there is a possible interaction, Dinogest 2 mg Combipack 10's can be taken with Bosentan if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DienogestFosphenytoin
Severe
How does the drug interact with Dinogest 2 mg Combipack 10's:
When Dinogest 2 mg Combipack 10's is taken with Fosphenytoin, it can increase the risk of severe bleeding.

How to manage the interaction:
Although taking Dinogest 2 mg Combipack 10's and Fosphenytoin together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like unusual bleeding, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Dinogest 2 mg Combipack 10's with Grapefruit and Grapefruit juice may increase the side effects of Dinogest 2 mg Combipack 10's. Consuming Grapefruit and grapefruit juice should be avoided while taking Dinogest 2 mg Combipack 10's.

Diet & Lifestyle Advise

  • Include diet-fibrous foods, iron-rich foods, foods rich in essential fatty acids, and anti-oxidant rich food.

  • Maintain a healthy diet and exercise regularly.

  • Practice meditation and yoga. Acupuncture and massages can also be helpful.

  • Avoid or limit caffeine intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

Dinogest 2 mg Combipack Substitute

Substitutes safety advice
  • Visanne Tablet 28's

    by AYUR

    116.12per tablet
  • Dinogest Tablet 10's

    by AYUR

    54.23per tablet
  • Endoreg Tablet 14's

    by AYUR

    56.31per tablet
  • Emersa Tablet 10's

    by AYUR

    58.77per tablet
  • Dinofirst Tablet 15's

    55.44per tablet
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Alcohol

Caution

It is unknown if Dinogest 2 mg Combipack interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Dinogest 2 mg Combipack is not recommended during pregnancy. Please consult your doctor if you have any concerns regarding this. Consult your doctor immediately if you become pregnant while taking Dinogest 2 mg Combipack .

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Breast Feeding

Unsafe

Avoid taking Dinogest 2 mg Combipack if you are breastfeeding. Please consult your doctor if you have any concerns regarding this.

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Driving

Caution

Dinogest 2 mg Combipack may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be necessary. Dinogest 2 mg Combipack should not be taken by people with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Dinogest 2 mg Combipack should not be given to children who have not had their first period.

FAQs

Dinogest 2 mg Combipack is indicated for the management of painful symptoms of endometriosis, a condition in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus.
Dinogest 2 mg Combipack suppresses the production of a hormone called estradiol which causes excess growth of the endometrium. Thereby, Dinogest 2 mg Combipack helps in treating pelvic pain associated with endometriosis.
Dinogest 2 mg Combipack may cause weight gain. Maintain a healthy weight by exercising regularly. Try eating smaller but more frequent meals. Consult your doctor if you notice severe weight gain.
Do not stop taking Dinogest 2 mg Combipack on your own. Continue taking Dinogest 2 mg Combipack for as long as your doctor has prescribed it for you depending on your condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Dinogest 2 mg Combipack .
Avoid using hormonal contraceptives with Dinogest 2 mg Combipack ; instead, use non-hormonal contraceptive methods such as condoms or barrier methods. Please consult your doctor; he/she may advise regarding proper contraception.
Antibiotics and antifungal medicines might affect how Dinogest 2 mg Combipack works or might be affected by Dinogest 2 mg Combipack . Therefore, consult your doctor before taking antibiotics or antifungals with Dinogest 2 mg Combipack .
Dinogest 2 mg Combipack may cause irregular menstrual bleeding or infrequent periods. Talk to your doctor if you experience this.
Long term use of Dinogest 2 mg Combipack might lower bone mineral density and affect bone health. An adequate intake of calcium and vitamin D either via your food or supplements may be helpful.
Dinogest 2 mg Combipack should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of treatment based on your condition.
Dinogest 2 mg Combipack should be swallowed as a whole with water; do not crush or chew it.
Dinogest 2 mg Combipack contains dienogest, which belongs to a group of medicines called progestin and is indicated for the management of endometriosis.
Yes, Dinogest 2 mg Combipack is a synthetic steroid.
Dinogest 2 mg Combipack helps endometriosis by suppressing the production of a hormone called estradiol, which causes excess growth in the endometrium.
Dinogest 2 mg Combipack may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Talk to your doctor if any of the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

A-10, 3Rd Floor, Art Guild House, Phoenix Market City Annexe, Lbs Marg, Kurla (West), Mumbai - 400070
Other Info - DIN0070

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