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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
DINMEK TABLET is used to treat HIV infection. It works by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus. In some cases, this medicine may cause side effects such as nausea, headache, dizziness, weakness, tiredness, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About DINMEK TABLET

DINMEK TABLET belongs to the class of ‘antiretrovirals,’ used to treat HIV infection. DINMEK TABLET helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

DINMEK TABLET is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil. Efavirenz is a non-nucleoside reverse transcriptase inhibitor. Lamivudine is a nucleoside reverse transcriptase inhibitor. Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus. 

Your doctor will decide the dosage based on your medical condition. Sometimes, DINMEK TABLET may have common side effects like nausea, headache, dizziness, depression, sleeping problems, weakness, tiredness, cough, rash, unusual dreams, concentration problems, drowsiness (sleepiness), and diarrhoea. These side effects do not require medical attention and gradually resolve over time. However, if these side effects persist for a longer time, please seek medical advice.

Let your doctor know if you are using a prescription, non-prescription drugs, and herbal products before starting DINMEK TABLET . If you are known to be allergic to DINMEK TABLET or its inactive components, please inform your doctor. Please tell your doctor if you have any heart problems, liver or kidney diseases, alcohol addiction, fits, high cholesterol levels, and weak/broken bones. If you are pregnant, please consult your doctor before taking DINMEK TABLET . Do not breastfeed while taking DINMEK TABLET . DINMEK TABLET is recommended for children who weigh at least 77 pounds (35 kg).

Uses of DINMEK TABLET

Treatment of HIV infection.

Medicinal Benefits

DINMEK TABLET is used to treat HIV infection. It consists of three medicines, namely: Efavirenz, Lamivudine, and Tenofovir disoproxil. Efavirenz belongs to the class of non-nucleoside reverse transcriptase inhibitors. Lamivudine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus. 

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DINMEK TABLET

  • Nausea
  • Headache
  • Dizziness
  • Depression
  • Sleeping problems
  • Weakness
  • Tiredness
  • Cough
  • Rash
  • Unusual dreams
  • Concentration problems
  • Drowsiness (sleepiness)
  • Diarrhoea

Drug Warnings

Let your doctor know if you are using a prescription, non-prescription drugs, and herbal products before starting DINMEK TABLET . Inform your doctor if you are allergic to DINMEK TABLET or its inactive components. Please inform your doctor if you have heart problems, liver (hepatitis B or C, cirrhosis) or kidney diseases, depression, pancreas (inflammation of the pancreas), alcohol addiction, fits, high cholesterol levels, and weak/broken bones (osteoporosis). You are advised to take proper precautions if you are infected with HIV infection to prevent the spread of infection to others through sexual contact or body fluids. DINMEK TABLET should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis. Pregnant women should consult their doctor before taking DINMEK TABLET . It is not recommended to breastfeed while using DINMEK TABLET since it excretes into the breast milk. DINMEK TABLET may cause dizziness/drowsiness, so do not drive or operate heavy machinery if you feel dizzy or drowsy.

Drug Interactions

Drug-Drug Interaction: DINMEK TABLET may interact with antifungal drugs (amphotericin B), antivirals (foscarnet, ganciclovir, cidofovir), drugs treating obesity (orlistat), medicines used to treat chronic hepatitis B infection (adefovir), medicines treating chronic hepatitis C (ombitasvir, paritaprevir, ritonavir, dasabuvir), immunosuppressants (tacrolimus), antibiotics (amikacin, gentamicin, pentamidine, vancomycin), and fits medicines (carbamazepine).

Drug-Food Interaction: DINMEK TABLET may have interaction with St.John’s wort (herbal supplement used to treat depression). Avoid alcohol consumption while being treated with this medication.

Drug-Disease Interaction: DINMEK TABLET should not be used in patients with liver diseases, kidney diseases, mood disorders, heart diseases, hypercholesterolemia (high cholesterol levels in the body), bone disorders, lactic acidosis, and immune reconstitution syndrome.

Drug-Drug Interactions Checker List

  • AMPHOTERICIN B
  • FOSCARNET
  • GANCICLOVIR
  • CIDOFOVIR
  • ORLISTAT
  • ADEFOVIR
  • OMBITASVIR
  • PARITAPREVIR
  • RITONAVIR
  • DASABUVIR
  • TACROLIMUS
  • AMIKACIN
  • GENTAMICIN
  • PENTAMIDINE
  • VANCOMYCIN
  • CARBAMAZEPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis as they can make you prone to HIV infection.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or do whatever makes you happy.

Special Advise

Regular kidney and liver function tests, bone mineral density tests are recommended while taking DINMEK TABLET .

Disease/Condition Glossary

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms, such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. HIV spreads through body fluids, such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs.

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Alcohol

Caution

Avoid alcohol consumption with DINMEK TABLET as it may increase the risk of liver damage.

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Pregnancy

Caution

DINMEK TABLET is not recommended for use in pregnant women unless necessary. Let your doctor know if you are pregnant or planning to conceive before taking DINMEK TABLET .

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Breast Feeding

Caution

DINMEK TABLET is not recommended for use in breastfeeding women since it is excreted into breast milk. Please consult your doctor before taking DINMEK TABLET if you are breastfeeding.

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Driving

Caution

DINMEK TABLET may cause dizziness and drowsiness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy or drowsy after taking DINMEK TABLET .

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking DINMEK TABLET . Dose adjustment may be required.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking DINMEK TABLET . Dose adjustment may be required.

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Children

Caution

DINMEK TABLET is recommended for children who weigh at least 77 pounds (35 kg) only under the doctor’s supervision.

Country of origin

India

Manufacturer/Marketer address

Plot No. -810, Sector - 3 , Industrial Area , Pthampur Dist. Dhar - 454 775 (M.P.) India
Other Info - DIN0032

Author Details

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FAQs

DINMEK TABLET contains Efavirenz, Lamivudine, and Tenofovir disoproxil. It works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, DINMEK TABLET helps in treating HIV infection.
DINMEK TABLET may cause bone problems, such as osteonecrosis (death of bone tissue due to loss of blood supply to the bone), especially in HIV patients taking combination antiretroviral therapy. If you experience any joint pains, stiffness (especially shoulder, knee or hip) or difficulty in movement, please consult a doctor immediately.
HIV infection may still be transmitted to other persons while using DINMEK TABLET . DINMEK TABLET reduces the risk of transmission; however, HIV infection is still contagious. Therefore, discuss with a doctor for precautions to avoid transmission of HIV while being treated with DINMEK TABLET .
DINMEK TABLET does not cure HIV infection. DINMEK TABLET reduces the activity of HIV in the body and improves the functioning of the immune system.
DINMEK TABLET may cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are very obese and in people with liver diseases. However, if you experience stomach pain, vomiting or nausea while taking DINMEK TABLET , please consult a doctor immediately.

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