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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Dilantin-Amp 2Ml is an anti-epileptic medication used in the treatment of severe epileptic seizures/fits, to prevent seizures during or after severe head injury and/or neurosurgery. This medicine works by decreasing the abnormal electrical activity in the brain and thus reduces seizures. Common side effects include nausea, vomiting, headache, and constipation.
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Prescription drug

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Composition

PHENYTOIN-200MG

Manufacturer/Marketer

Pfizer Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Dilantin-Amp 2Ml

Dilantin-Amp 2Ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Dilantin-Amp 2Ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm).

Dilantin-Amp 2Ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Dilantin-Amp 2Ml helps prevent and treat epileptic seizures. Dilantin-Amp 2Ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Dilantin-Amp 2Ml will be administered by a healthcare professional; do not self-administer. In some cases, Dilantin-Amp 2Ml may cause certain common side-effects such as nausea, vomiting, headache, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Dilantin-Amp 2Ml. Avoid driving or operating heavy machinery as Dilantin-Amp 2Ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Dilantin-Amp 2Ml

Treatment of Epilepsy/Seizures and Cardiac arrhythmia

Medicinal Benefits

Dilantin-Amp 2Ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Dilantin-Amp 2Ml works by decreasing the abnormal electrical activity in the brain. Thereby, Dilantin-Amp 2Ml helps prevent and treat epileptic seizures. Dilantin-Amp 2Ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm). Dilantin-Amp 2Ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Directions for Use

Dilantin-Amp 2Ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dilantin-Amp 2Ml

  • Nausea
  • Vomiting
  • Headache
  • Constipation
  • Abnormal eye movement
  • Slurred speech
  • Confusion
  • Problems with coordination

Drug Warnings

Do not take Dilantin-Amp 2Ml if you are allergic to any of its contents. Inform your doctor if you have decreased heart rate, heart block, low blood pressure, heart failure, diabetes, porphyria (blood disorder), heart rhythm problems, alcohol dependence, kidney or liver problems. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Dilantin-Amp 2Ml. Do not drive or operate heavy machinery as Dilantin-Amp 2Ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood.

Drug Interactions

Drug-Drug Interactions: Dilantin-Amp 2Ml may have interaction with anti-HIV drugs (delavirdine), painkillers (aspirin, acetaminophen), blood thinners (warfarin, clopidogrel), anti-convulsant (gabapentin, pregabalin), anti-depressant (quetiapine), diuretic (furosemide), cholesterol-lowering agent (atorvastatin), a drug used to treat thyroid deficiency (levothyroxine), supplements (ergocalciferol, cholecalciferol).

Drug-Food Interactions: Do not take Dilantin-Amp 2Ml with St. John's wort (an antidepressant herbal supplement).

Drug-Disease Interactions: Inform your doctor if you have/had decreased heart rate, heart block, low blood pressure, heart failure, diabetes, or porphyria (blood disorder).

Drug-Drug Interactions Checker List

  • DELAVIRDINE
  • ASPIRIN
  • ACETAMINOPHEN
  • WARFARIN
  • CLOPIDOGREL
  • GABAPENTIN
  • PREGABALIN
  • QUETIAPINE
  • FUROSEMIDE
  • ATORVASTATIN
  • LEVOTHYROXINE
  • ERGOCALCIFEROL
  • CHOLECALCIFEROL

Habit Forming

No

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, this helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.

Special Advise

Consult your doctor immediately if you have suicidal thoughts such as harming or killing yourself.

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Cardiac arrhythmia: Cardiac arrhythmia is a condition in which the heartbeats are abnormal or irregular. It occurs when the electrical signals in the heart do not work properly. Symptoms may include palpitations (a feeling as if the heart is pounding), chest pain, fainting, and dizziness.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Dilantin-Amp 2Ml to prevent unpleasant side-effects. It might also affect the concentration of phenytoin in the blood.

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Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Dilantin-Amp 2Ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Dilantin-Amp 2Ml. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Dilantin-Amp 2Ml may cause dizziness and drowsiness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Dilantin-Amp 2Ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Dilantin-Amp 2Ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Dilantin-Amp 2Ml can be given to children if prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - DIL0043

Author Details

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FAQs

Dilantin-Amp 2Ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus), and prevent seizures during or after severe head injury and/or neurosurgery. Dilantin-Amp 2Ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion.
Dilantin-Amp 2Ml works by controlling overactivity of the brain that causes seizures (fits). Thereby, Dilantin-Amp 2Ml helps in controlling epileptic fits.
Dilantin-Amp 2Ml can make hormonal contraceptives less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.
Dilantin-Amp 2Ml may cause hyperglycemia (high blood glucose levels). So, inform your doctor if you have diabetes.
Dilantin-Amp 2Ml may affect the metabolism of vitamin D, which could cause osteomalacia. Inform your doctor if you have bone problems.
Dilantin-Amp 2Ml might increase blood sugar levels and decrease blood calcium levels, folic acid, phosphate, and vitamin D levels. Inform the person doing the tests that you are taking Dilantin-Amp 2Ml.

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