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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Dilantin-Amp 2Ml is an anti-epileptic medication used in the treatment of severe epileptic seizures/fits, to prevent seizures during or after severe head injury and/or neurosurgery. This medicine works by decreasing the abnormal electrical activity in the brain and thus reduces seizures. Common side effects include nausea, vomiting, headache, and constipation.
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Whats That

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Composition :

PHENYTOIN-200MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Dilantin-Amp 2Ml

Dilantin-Amp 2Ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Dilantin-Amp 2Ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm).

Dilantin-Amp 2Ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Dilantin-Amp 2Ml helps prevent and treat epileptic seizures. Dilantin-Amp 2Ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Dilantin-Amp 2Ml will be administered by a healthcare professional; do not self-administer. In some cases, Dilantin-Amp 2Ml may cause certain common side-effects such as nausea, vomiting, headache, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Dilantin-Amp 2Ml. Avoid driving or operating heavy machinery as Dilantin-Amp 2Ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Dilantin-Amp 2Ml

Treatment of Epilepsy/Seizures and Cardiac arrhythmia

Directions for Use

Dilantin-Amp 2Ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Dilantin-Amp 2Ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Dilantin-Amp 2Ml works by decreasing the abnormal electrical activity in the brain. Thereby, Dilantin-Amp 2Ml helps prevent and treat epileptic seizures. Dilantin-Amp 2Ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm). Dilantin-Amp 2Ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

How Dilantin-Amp 2Ml Works

Dilantin-Amp 2Ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Dilantin-Amp 2Ml helps prevent and treat epileptic seizures. Dilantin-Amp 2Ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dilantin-Amp 2Ml

  • Nausea
  • Vomiting
  • Headache
  • Constipation
  • Abnormal eye movement
  • Slurred speech
  • Confusion
  • Problems with coordination

What if I have taken an overdose of Dilantin-Amp 2Ml

Dilantin-Amp 2Ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. The neurotoxic effects vary in severity depending on the concentration and can include lethargy, vomiting, ataxia, slurred speech, mild nystagmus, coma, and death. Ironically, phenytoin can cause seizures at very high concentrations. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Dilantin-Amp 2Ml if you are allergic to any of its contents. Inform your doctor if you have decreased heart rate, heart block, low blood pressure, heart failure, diabetes, porphyria (blood disorder), heart rhythm problems, alcohol dependence, kidney or liver problems. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Dilantin-Amp 2Ml. Do not drive or operate heavy machinery as Dilantin-Amp 2Ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood.

Drug-Drug Interactions

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PhenytoinRanolazine
Critical
PhenytoinCeritinib
Critical

Drug-Drug Interactions

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PhenytoinRanolazine
Critical
How does the drug interact with Dilantin-Amp 2Ml:
Using ranolazine together with Dilantin-Amp 2Ml may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Dilantin-Amp 2Ml with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PhenytoinCeritinib
Critical
How does the drug interact with Dilantin-Amp 2Ml:
Taking ceritinib with Dilantin-Amp 2Ml may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Dilantin-Amp 2Ml with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PhenytoinPraziquantel
Critical
How does the drug interact with Dilantin-Amp 2Ml:
Using praziquantel together with Dilantin-Amp 2Ml may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Dilantin-Amp 2Ml with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Dilantin-Amp 2Ml:
Using Dilantin-Amp 2Ml together with cimetidine may increase the effects of Dilantin-Amp 2Ml.

How to manage the interaction:
Taking Dilantin-Amp 2Ml with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinRilpivirine
Critical
How does the drug interact with Dilantin-Amp 2Ml:
Using rilpivirine together with Dilantin-Amp 2Ml may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Dilantin-Amp 2Ml is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Dilantin-Amp 2Ml:
Using Dilantin-Amp 2Ml together with Cimetidin may increase the effects of Dilantin-Amp 2Ml.

How to manage the interaction:
Taking Dilantin-Amp 2Ml with Cimetidine can cause an interaction, consult a doctor before taking it. Contact a doctor if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinLurasidone
Critical
How does the drug interact with Dilantin-Amp 2Ml:
Using lurasidone together with Dilantin-Amp 2Ml may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Dilantin-Amp 2Ml is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PhenytoinVenetoclax
Critical
How does the drug interact with Dilantin-Amp 2Ml:
Using venetoclax together with Dilantin-Amp 2Ml may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Dilantin-Amp 2Ml with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinIsavuconazole
Critical
How does the drug interact with Dilantin-Amp 2Ml:
Co-administration of Dilantin-Amp 2Ml and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Dilantin-Amp 2Ml is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
PhenytoinQuetiapine
Severe
How does the drug interact with Dilantin-Amp 2Ml:
Coadministration of quetiapine and Dilantin-Amp 2Ml may reduce the blood levels of quetiapine, which may make the medication less effective in treating your condition.

How to manage the interaction:
Although taking Dilantin-Amp 2Ml and Quetiapine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, this helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Dilantin-Amp 2Ml Substitute

Substitutes safety advice
  • Epsolin ER 200 mg Capsule 30's

    8.79per tablet
  • I-Toin ER 200 Tablet 30's

    7.00per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Dilantin-Amp 2Ml to prevent unpleasant side-effects. It might also affect the concentration of phenytoin in the blood.

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Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Dilantin-Amp 2Ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Dilantin-Amp 2Ml. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Dilantin-Amp 2Ml may cause dizziness and drowsiness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Dilantin-Amp 2Ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Dilantin-Amp 2Ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Dilantin-Amp 2Ml can be given to children if prescribed by the doctor.

FAQs

Dilantin-Amp 2Ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus), and prevent seizures during or after severe head injury and/or neurosurgery. Dilantin-Amp 2Ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion.
Dilantin-Amp 2Ml works by controlling overactivity of the brain that causes seizures (fits). Thereby, Dilantin-Amp 2Ml helps in controlling epileptic fits.
Dilantin-Amp 2Ml can make hormonal contraceptives less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.
Dilantin-Amp 2Ml may cause hyperglycemia (high blood glucose levels). So, inform your doctor if you have diabetes.
Dilantin-Amp 2Ml may affect the metabolism of vitamin D, which could cause osteomalacia. Inform your doctor if you have bone problems.
Dilantin-Amp 2Ml might increase blood sugar levels and decrease blood calcium levels, folic acid, phosphate, and vitamin D levels. Inform the person doing the tests that you are taking Dilantin-Amp 2Ml.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - DIL0043

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