Difpru Ophthalmic Emulsion belongs to the class of ocular medications called ‘topical corticosteroids’ used to treat inflammatory conditions after eye surgery.  It is effectively used to treat eye inflammation caused by allergies, iritis (inflammation of the coloured part of the eye (iris)), uveitis (inflammation of the middle layer of the eye (uvea)), eye injury, postinfectious pain and inflammation.

Difpru Ophthalmic Emulsion contains Difluprednate, a topical corticosteroid with anti-inflammatory properties and acts by inhibiting the chemicals such as prostaglandins production (chemical messengers) that make the eye red, swollen and itchy. It is used to treat post-operative eye pain and inflammation.

Difpru Ophthalmic Emulsion is for ophthalmic (use in the eyes) use only. Use Difpru Ophthalmic Emulsion as prescribed by your doctor. You are advised to use Difpru Ophthalmic Emulsion for as long as your doctor has prescribed it based on your medical condition. You may experience watery eyes, irritation, eye itching, and eyes more sensitivity to light in some cases. Most of these side effects of Difpru Ophthalmic Emulsion are temporary, do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use Difpru Ophthalmic Emulsion without consulting your doctor if you have a damaged cornea, ulcers in the eye, eye infection producing pus, open lesions in the eye and glaucoma (a condition where the pressure inside the eye increases). Inform your doctor if you are pregnant or breastfeeding before using Difpru Ophthalmic Emulsion. If you wear contact lenses, remove them before using Difpru Ophthalmic Emulsion, and you can put it back 15 minutes after using Difpru Ophthalmic Emulsion. Avoid touching the eyedropper with bare hands or taking it closer to the eyelids while administering drops since it contaminates the dropper tip and solution. If you wear contact lenses, please inform your doctor.

Difpru Ophthalmic Emulsion contains Difluprednate used to treat post-operative eye pain and inflammation. Difpru Ophthalmic Emulsion is a topical corticosteroid with anti-inflammatory properties and acts by inhibiting the chemicals such as prostaglandins production (chemical messengers) that make the eye red, swollen and itchy. Difpru Ophthalmic Emulsion is also used to treat post-infectious swelling and pain of the eyes, treat anterior uveitis, and inflammation that affects the front part of the eye.

• Eye itching/irritation
• Watery eyes
• Headache
• Blurred vision
• Eyes more sensitive to light

Do not take Difpru Ophthalmic Emulsion if you are allergic or have had a severe reaction to the corticosteroids or any of the ingredients of Difpru Ophthalmic Emulsion.  Please inform your doctor if you are pregnant or breastfeeding before starting Difpru Ophthalmic Emulsion. Difpru Ophthalmic Emulsion is not recommended for children below 1 year of age as the safety and effectiveness have not been established. Do not stop taking Difpru Ophthalmic Emulsion even if you feel better without asking your doctor, as your symptoms may come back and even worsen your condition. To avoid any contamination, avoid touching the tip of the dropper. Do not put in other eye medication simultaneously; wait for at least 15 minutes before putting in the second medication. If you have had glaucoma (increased eye pressure), herpes simplex infection, or any other eye problem, do not take Difpru Ophthalmic Emulsion until prescribed by your doctor. Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve and defects in visual acuity and fields of vision. Do not use eye drops for longer than recommended by your doctor as they may suppress adrenal gland function and may increase the risk of cataracts (clouding of the eye) and also increases the risk of a second infection.

Drug-drug interactions: Difpru Ophthalmic Emulsion may interact with a smallpox vaccine.

Drug-food interactions: No interactions found.

Drug-disease interactions: Difpru Ophthalmic Emulsion should not be used in patients with fungal infections, viral infections such as herpes simplex or varicella or parasitic infections such as amoebiasis, tuberculosis, damaged cornea, ulceration and glaucoma (increased pressure inside the eye).

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• Try to maintain good hygiene to keep your eyes clean and irritant-free.
• Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
• Know your allergy triggers, such as pollen, dust and other factors.
• Sleep for at least six to eight hours to rejuvenate your eyes naturally.
• Wash your eyes with clean water at least two to three times a day
• Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep.
• Wash your hands thoroughly, and do not touch the dropper before using drops to avoid contamination.
• Reduce screen time (by avoiding watching tv or phone) and use sunglasses while going into the sunlight.

• If you are using other eye drops along with Difpru Ophthalmic Emulsion, maintain at least 15 minutes before administering other medicines in the same eye to avoid dilution. 
• Have frequent follow-up check-ups with your doctor to check for any problems, such as cataracts or increased pressure.

Endophthalmitis: Endophthalmitis is the medical term for significant inflammation within the eye. It can happen after some type of eye surgery or if the eye is penetrated by an external item. People with glaucoma surgery (such as glaucoma filtering) or cataract surgery are at life-long risk of getting endophthalmitis. Eye pain that intensifies following surgery or injury to the eye, as well as diminished or loss of vision, are symptoms. Anterior uveitis is an inflammation of the middle layer of the eye, including the iris and adjacent tissue, known as the ciliary body.