Difizma Capsule (Inhalation Powder) 10's

Difizma Capsule (Inhalation Powder) is indicated as a maintenance treatment of asthma in adults. Asthma is a long-term lung disease where the muscles around the smaller airways become tight (bronchoconstriction) and inflamed, leading to difficulty in breathing.

Difizma Capsule (Inhalation Powder) is a combination of three drugs: Glycopyrronium Bromide and Indacaterol (bronchodilators), and Mometasone Furoate (corticosteroids). Glycopyrronium Bromide and Indacaterol relax the muscles of the small airways in the lungs, which helps open the airways and makes it easier for air to get in and out. Mometasone Furoate reduces the inflammation (swelling and irritation) in the small airways in the lungs. This gradually eases breathing problems and also helps to prevent asthma attacks.

Difizma Capsule (Inhalation Powder) is for inhalation only. Do not swallow Difizma Capsule (Inhalation Powder) . Use Difizma Capsule (Inhalation Powder) as prescribed by your doctor. You are advised to use Difizma Capsule (Inhalation Powder) for as long as your doctor has advised it based on your medical condition. Difizma Capsule (Inhalation Powder) may cause common side effects such as runny nose, sore throat, sudden difficulty breathing and chest tightness with coughing or wheezing, oral thrush (a fungal infection in the mouth), headache or fast heartbeat. Most of these side effects of Difizma Capsule (Inhalation Powder) do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to mometasone furoate, indacaterol, glycopyrronium bromide, or any other ingredients of Difizma Capsule (Inhalation Powder) , please tell your doctor. Difizma Capsule (Inhalation Powder) is not recommended for children below 18 years. If you are pregnant or breastfeeding, take your doctor’s advice before using Difizma Capsule (Inhalation Powder) . If you have chest tightness, wheezing, coughing or breathlessness immediately after using Difizma Capsule (Inhalation Powder) , stop using it and consult a doctor right away as these may be signs of unexpected airways tightening.

Difizma Capsule (Inhalation Powder) belongs to the class of respiratory stimulants. It contains Glycopyrronium Bromide, Indacaterol and Mometasone Furoate. Difizma Capsule (Inhalation Powder) is used as a maintenance treatment of asthma in adults not adequately controlled with a maintenance combination of a long-acting beta2-agonist and a high dose of an inhaled corticosteroid who experienced one or more asthma flare-ups in the previous year. Difizma Capsule (Inhalation Powder) relaxes the muscles of the small airways in the lungs and reduces inflammation (swelling and irritation). This gradually eases breathing problems and also helps to prevent asthma attacks.

• Runny nose
• Sore throat
• Sudden difficulty breathing and chest tightness with coughing or wheezing
• Oral thrush (fungal infection in the mouth)
• Headache
• Fast heartbeat

If you are allergic to mometasone furoate, indacaterol, glycopyrronium bromide, or any other ingredients of Difizma Capsule (Inhalation Powder) , please tell your doctor. Difizma Capsule (Inhalation Powder) is not recommended for children below 18 years. If you are pregnant or breastfeeding, take your doctor’s advice before using Difizma Capsule (Inhalation Powder) . If you have chest tightness, wheezing, coughing or breathlessness immediately after using Difizma Capsule (Inhalation Powder) , stop using it and consult a doctor right away as these may be signs of unexpected airways tightening. If you have eye pain or discomfort, visual haloes (seeing bright circles around lights), temporary blurring of vision, or coloured images in association with red eyes, contact your doctor, as these may be signs of an attack of angle-closure glaucoma. If your asthma is not getting better or if it worsens after you have started using Difizma Capsule (Inhalation Powder) , talk to your doctor.

Drug-Drug Interaction: Inform your doctor if you are taking diuretics (hydrochlorothiazide), other bronchodilators (theophylline), corticosteroids (prednisolone), antidepressants, drugs used to lower high blood pressure (propranolol), anti-glaucoma drug (timolol), antifungals (itraconazole, ketoconazole), and medicines used to treat HIV infection (cobicistat, ritonavir, nelfinavir).

Drug-Drug Interaction: Inform your doctor if you are taking diuretics (hydrochlorothiazide), other bronchodilators (theophylline), corticosteroids (prednisolone), antidepressants, drugs used to lower high blood pressure (propranolol), anti-glaucoma drug (timolol), antifungals (itraconazole, ketoconazole), and medicines used to treat HIV infection (cobicistat, ritonavir, nelfinavir).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have diabetes, seizures (fits), tuberculosis (TB), low potassium levels in the blood, angle-closure glaucoma, difficulty passing urine, thyroid gland, kidney, liver or heart problems, inform your doctor before using Difizma Capsule (Inhalation Powder) .

• HYDROCHLOROTHIAZIDE
• THEOPHYLLINE
• PREDNISOLONE
• PROPRANOLOL
• TIMOLOL
• ITRACONAZOLE
• KETOCONAZOLE
• COBICISTAT
• RITONAVIR
• NELFINAVIR

• Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
• Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon, and lime juice, as they may worsen asthma symptoms.
• Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
• Quit smoking as it may reduce the effectiveness of the Difizma Capsule (Inhalation Powder) and irritate the lungs, worsening breathing problems.
• Learning breathing exercises will help you move more air in and out of your lungs.

Asthma: It is a chronic (long-term) lung disease where the muscles around the smaller airways become tight (bronchoconstriction) and inflamed, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), chest tightness, cough and shortness of breath, especially at night. The symptoms of mild persistent asthma may occur more than two times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The asthma treatment includes medication, breathing exercises, and self-care.