Difidox Injection belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Difidox Injection may also be used to treat or prevent anthrax.

Difidox Injection contains 'Doxycycline' which stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Difidox Injection helps treat bacterial infections. It is a broad-spectrum antibiotic which is effective against both gram-negative and gram-positive bacteria.

Difidox Injection will be administered by a healthcare professional; do not self-administer. In some cases, Difidox Injection may cause pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea. Most of these side effects of Difidox Injection do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Do not take Difidox Injection if you are allergic to any of the components. Consult your doctor if you are pregnant or breastfeeding. Use of Difidox Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Difidox Injection belongs to the class of medicines called tetracycline antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites. It is used to treat respiratory tract infections (influenza, pneumonia), genitourinary infections (syphilis, gonorrhoea), anthrax infection, sinuses, eye, and skin infections. Besides this, it is also indicated in the tick-borne infections (typhus fever) caused by the Rickettsia group of bacteria like typhus fever. Off-label, usage includes the prevention of malaria and the treatment of acne.

• Pain, itching, swelling or redness at the site of injection
• Nausea
• Vomiting
• Diarrhoea

Do not take Difidox Injection if you are allergic to any of its contents. Inform your doctor if you have lupus, or if you are pregnant or breastfeeding.  Use of Difidox Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Consult your doctor if you experience any skin reactions, fever,  muscle, or joint problems.

Drug-Drug Interactions: Difidox Injection may interact with retinoid medications taken by mouth (acitretin, isotretinoin), blood thinners (warfarin), heart disease medicine (digoxin), anti-seizure medications (phenytoin, carbamazepine), antacids containing aluminium, calcium, or magnesium, bismuth subsalicylate, iron supplements, and oral birth control pills. 

Drug-Food Interactions: Food containing calcium and iron should be avoided within 2 hours of Difidox Injection as it may affect Difidox Injection effectiveness.

Drug-Disease Interactions: Inform your doctor if you have kidney problems, liver problems, swollen food pipe (esophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis).

• ACITRETIN
• ISOTRETINOIN
• WARFARIN
• DIGOXIN
• PHENYTOIN
• CARBAMAZEPINE
• ALUMINIUM
• CALCIUM
• MAGNESIUM
• BISMUTH SUBSALICYLATE

• It would be best to take probiotics after completing the full course of Difidox Injection to restore healthy bacteria in the intestine that may have been killed due to the usage of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
• Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole-grain bread, and brown rice, should be included in your diet.
• Avoid taking too much calcium enriched foods and drinks as it might affect the working of Difidox Injection.
• Avoid intake of alcoholic beverages with Difidox Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Difidox Injection in fighting off infections.

• Wear sunglasses and sunscreen when you go out in the sun as Difidox Injection can make your skin sensitive to light.
• Maintain a gap of 2 hours between Difidox Injection and iron supplements and antacids as taking them together might affect the working of Difidox Injection.
• Difidox Injection might affect certain lab tests, inform the person doing the tests that you are taking Difidox Injection.

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.