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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:27 PM IST
Diclowox P 50mg/325mg Tablet is used to treat painful musculoskeletal joint conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It contains Diclofenac and Paracetamol. Diclofenac reduces the production of prostaglandins (chemicals) that cause pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), enhancing Diclofenac's pain relief action. It also helps relieve toothache, ear pain, backache and other musculoskeletal-related pain. It may cause common side effects like stomach upset, dizziness, light-headedness, malaise, nausea, vomiting, liver dysfunction (hepatitis), pruritis (itchy skin), and rash.
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Manufacturer/Marketer

Woxter Pharma

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Diclowox P 50mg/325mg Tablet

Diclowox P 50mg/325mg Tablet is used to treat painful musculoskeletal joint conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Diclowox P 50mg/325mg Tablet contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic), effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), enhancing Diclofenac's pain relief action. It also helps relieve toothache, ear pain, backache and other musculoskeletal-related pain.

Diclowox P 50mg/325mg Tablet can be taken with or after the meal. Diclowox P 50mg/325mg Tablet may cause common side effects like stomach upset, dizziness, light-headedness, malaise, nausea, vomiting, liver dysfunction (hepatitis), pruritis (itchy skin), and rash, although not everybody gets them. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.

Diclowox P 50mg/325mg Tablet is not recommended during the last three months of pregnancy and for children. Inform your doctor if you are pregnant or breastfeeding before receiving this injection. Keep your doctor informed about your health condition and ongoing medicines to rule out any side effects/interactions. Stop taking this medicine if you experience symptoms like tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate, and or in case of any signs of hypersensitivity.

Uses of Diclowox P 50mg/325mg Tablet

Treatment of Pain relief (Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis).

Medicinal Benefits

Diclowox P 50mg/325mg Tablet contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic), effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), enhancing Diclofenac's pain relief action. It also helps relieve toothache, ear pain, backache and other musculoskeletal-related pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Diclowox P 50mg/325mg Tablet

  • Dizziness
  • Light-headedness
  • Malaise (feeling of discomfort)
  • Nausea
  • Vomiting
  • Liver dysfunction

Drug Warnings

Do not take Diclowox P 50mg/325mg Tablet if you are allergic to any components present in it. Patients with asthma, prolonged bleeding time, wheezing (whistling sound during breath), and blocked airways (bronchospasm) should avoid using Diclowox P 50mg/325mg Tablet. It is not recommended for use in children less than 14 years of age, people with liver disease, heart disease, or gastric ulcers/bleeding problems. Diclowox P 50mg/325mg Tablet may be associated with a small increase in the risk of heart attack (myocardial infarction). Pregnant women should not take during their last trimester of pregnancy. Diclowox P 50mg/325mg Tablet is excreted in the breast milk, so the nursing mother should contact the doctor before its usage. Avoid the consumption of alcohol as it may damage your liver and cause even more side effects on taking this drug. Consult your doctor if your pain, inflammation, and fever symptoms do not disappear even after ten days.

Drug Interactions

Drug-Drug Interactions: Diclowox P 50mg/325mg Tablet is shown to interact with various drugs. Some of them include painkillers (naproxen, aspirin, ibuprofen, tramadol, hydrocodone, oxycodone), antibiotics (ciprofloxacin, levofloxacin, moxifloxacin, nalidixic acid, norfloxacin or ofloxacin), diuretics (furosemide and bumetanide), medicines for heart problems or medication for high blood pressure (digoxin), medicines used to lower cholesterol (colestipol and cholestyramine), drugs to treat seizures (phenytoin), medicines that reduce the activity of your immune system (ciclosporin or tacrolimus), steroid medicines (hydrocortisone or prednisolone), blood thinner (warfarin), anti-depressant (duloxetine) and acidity lowering drugs (cimetidine). These drugs may affect the working of Diclowox P 50mg/325mg Tablet and may alter its efficacy.

Drug-Food Interactions: Excessive caffeine-containing food or drinks like coffee, tea, chocolate and some fizzy drinks should be avoided while taking Diclowox P 50mg/325mg Tablet. Taking them together may lead to drowsiness and dizziness, and sleepiness.

Drug-Disease Interactions: Diclowox P 50mg/325mg Tablet interacts with disease conditions, including asthma, urticaria or acute rhinitis, as the attacks precipitate with NSAIDs.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • NAPROXEN
  • CIPROFLOXACIN
  • FUROSEMIDE
  • TRAMADOL
  • HYDROCODONE
  • OXYCODONE
  • LEVOFLOXACIN
  • MOXIFLOXACIN
  • NALIDIXIC ACID
  • NORFLOXACIN
  • OFLOXACIN
  • BUMETANIDE
  • DIGOXIN
  • COLESTIPOL
  • CHOLESTYRAMINE
  • PHENYTOIN
  • CICLOSPORIN
  • TACROLIMUS
  • HYDROCORTISONE
  • PREDNISOLONE
  • WARFARIN
  • DULOXETINE
  • CIMETIDINE

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.

  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Avoid smoking and alcohol consumption.

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, fractures, arthritis, and injury.

Musculoskeletal pain: It is generally caused by disorders of bones, joints, muscles, tendons, ligaments, or a combination. Injuries (mostly sports-related) are the most common cause of musculoskeletal pain. Muscle pain (myalgia) can be caused due to injury, infection, loss of blood flow to the muscle, infection, or a tumour. Extreme tissue pain and inflammation caused by sprains, strains, trauma, or post-surgery may require prolonged healing time.

Osteoarthritis: Osteoarthritis is the most common form of joint disorder, which occurs when the protective cartilage that cushions the ends of your bones wears down over time. It can damage any joint, affecting your hands, knees, hips and spine joints.

Ankylosing spondylitis: Ankylosing spondylitis is a painful condition in which fused bones of your spinal cord or vertebrae get inflamed, leading to a hunched spine. Symptoms of ankylosing spondylitis include decreased flexibility, which usually leads to a hunched-forward posture and pain in the back and joints.

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Alcohol

Caution

Drinking too much alcohol may irritate your stomach.

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Pregnancy

Unsafe

Diclowox P 50mg/325mg Tablet is not recommended for use in the last three months of pregnancy as it may harm the unborn child or cause problems at delivery. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Diclowox P 50mg/325mg Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving the Diclowox P 50mg/325mg Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Diclowox P 50mg/325mg Tablet may affect driving ability as it causes headaches, blurred vision, dizziness or drowsiness.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Diclowox P 50mg/325mg Tablet. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a history of kidney diseases, inform your doctor before receiving Diclowox P 50mg/325mg Tablet. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Diclowox P 50mg/325mg Tablet is not recommended for children below 14 years. For children above 14 years, this medicine can be given if a doctor prescribed it.

Country of origin

India
Other Info - DI33719

Author Details

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FAQs

Diclowox P 50mg/325mg Tablet is used to relieve pain associated with musculoskeletal joint conditions like osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Diclowox P 50mg/325mg Tablet contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic), effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), enhancing Diclofenac's pain relief action.
No, Diclowox P 50mg/325mg Tablet is not indicated for stomach pain. Also, If you have stomach pain post-ingestion it may be a sign of stomach ulcer or gastric bleeding. Do not take Diclowox P 50mg/325mg Tablet in this condition. It is better to inform your doctor in case of stomach pain post-ingestion of this medication.
No, do not take Diclowox P 50mg/325mg Tablet until prescribed by your doctor. For example, your shoulder pain may be due to lungs, spleen, or gallbladder problems. Your back pain may be due to kidney stones, pancreas swelling, or, in women, pelvic disorders. Your arm pain (especially the left arm) may be due to a heart attack (myocardial infarction).
Yes, Diclowox P 50mg/325mg Tablet is a short-term medication, and if you feel better, you can stop taking Diclowox P 50mg/325mg Tablet, but only after consulting your doctor.
Yes, the long-term use of Diclowox P 50mg/325mg Tablet can cause damage to the kidneys.
No, Diclowox P 50mg/325mg Tablet is not addictive, but it's important always to take it as prescribed.
No, Diclowox P 50mg/325mg Tablet should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For the best results of Diclowox P 50mg/325mg Tablet, take it in doses and duration mentioned by your doctor.
Before taking Diclowox P 50mg/325mg Tablet, inform your doctor about your medical history, allergies, and medications. This medication is not recommended for children, pregnant or breastfeeding women, or people with stomach ulcers or kidney or liver disease. Always follow the recommended dosage and monitor your blood pressure regularly. Read the label carefully and consult your doctor for any questions or concerns.
Diclofenac Paracetamol is not suitable for children under 14 years old. A doctor's guidance is necessary for teenagers between 14 and 18 to determine the correct dosage and treatment duration.
Diclowox P 50mg/325mg Tablet is a combination medication primarily used for the treatment of various types of pain, including Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis, and Ankylosing spondylitis. It contains two active ingredients: Diclofenac and Paracetamol.
Diclowox P 50mg/325mg Tablet is a safe and effective medication when used as directed. However, it's essential to be aware of potential side effects and take steps to minimize risks. Common side effects are usually mild and may include stomach upset, diarrhoea, headache, and dizziness. In rare cases, more serious issues can occur, such as stomach ulcers, kidney damage, or allergic reactions. To ensure safe use, always follow the recommended dosage, inform your doctor about your medical history and any other medications you're taking, and monitor your health closely.
Yes, the use of Diclowox P 50mg/325mg Tablet can cause nausea and vomiting in some individuals. These side effects usually fade away with time. Making some lifestyle changes, such as eating smaller meals or avoiding triggers, can also help alleviate symptoms. However, consult your doctor for further guidance and support if nausea and vomiting persist or worsen.
Yes, the use of Diclowox P 50mg/325mg Tablet causes dizziness in some individuals. This side effect is usually mild and temporary, but it can be a concern, especially for people who need to drive, operate heavy machinery, or perform other activities that require attention and balance. If you experience dizziness, get up slowly, avoid driving or operating heavy machinery, and hold onto something stable for support. Usually, dizziness caused by Diclofenac Paracetamol fades away with time. However, if the dizziness is severe, persists, or worsens, consult your doctor for further guidance and support.
Yes, the use of Diclowox P 50mg/325mg Tablet can potentially cause damage to the kidneys in some individuals, especially with long-term or high-dose use. This risk is higher in people with pre-existing kidney problems or those taking other medications that can harm the kidneys. However, by making healthy diet and lifestyle changes, taking medication as directed by your doctor, and undergoing regular monitoring, you can minimize this risk and protect your kidney health.
There are specific contraindications associated with the use of Diclowox P 50mg/325mg Tablet. Individuals with a known hypersensitivity to Diclofenac, Paracetamol, or other NSAIDs should avoid taking this medication. Additionally, it is contraindicated in patients with active peptic ulcer or bleeding, severe kidney or liver impairment, heart failure, or coronary artery disease. Pregnant women, especially in the third trimester, and breastfeeding mothers should also consult their doctor before taking Diclofenac Paracetamol. Furthermore, concomitant use of other NSAIDs or anticoagulants is not recommended.
Exercise caution when considering taking Diclowox P 50mg/325mg Tablet with Vitamin B-complex. While there may not be a known interaction, it's essential to consult your doctor or pharmacist before combining these medications. Do not take Diclowox P 50mg/325mg Tablet with Vitamin B-complex unless advised by your doctor, who can assess potential interactions and provide personalized guidance based on your specific health needs and medications.
No, taking a higher than the recommended dose of Diclowox P 50mg/325mg Tablet is unsafe. Taking more than the prescribed dose can increase the risk of serious side effects, including stomach ulcers, bleeding, kidney damage, and liver damage. Always follow your doctor's instructions and take the medication as directed. If you experience inadequate pain relief or have concerns about your dosage, consult your doctor for guidance. Never exceed the recommended dose without consulting your doctor.
The recommended storage condition for Diclowox P 50mg/325mg Tablet is to keep it in a cool and dry place away from direct sunlight. Additionally, keep it out of the sight and reach of children to avoid accidental ingestion.
It's generally not recommended to take Diclofenac Paracetamol while breastfeeding, as the medication may pass into breast milk and potentially harm the nursing infant. If you're breastfeeding and experiencing pain, consult your doctor or pharmacist for guidance on safe and alternative pain management options.
Diclowox P 50mg/325mg Tablet may cause common side effects such as stomach upset, dizziness, nausea, vomiting, liver dysfunction, itchy skin, and rash. Most of these side effects are mild and resolve on their own. However, consult your doctor for further guidance and care if they persist or worsen.
Taking other medicines with Diclowox P 50mg/325mg Tablet without consulting your doctor first is not recommended. Some medications can interact with Diclowox P 50mg/325mg Tablet, increasing the risk of adverse effects. Inform your doctor about all the medications you're currently taking, including prescription, over-the-counter, and herbal supplements, to ensure safe and effective treatment.

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