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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:28 PM IST
Dexon 4 mg Injection contains dexamethasone used to treat severe allergic conditions, collagen diseases, pulmonary disorders, blood disorders, rheumatic diseases, skin diseases, gastrointestinal disorders, etc. This medicine belongs to the corticosteroid class which works by inhibiting the production of certain chemical messengers in the body that cause inflammation. Thus, helps reduce swelling, redness, and itching.
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Manufacturer/Marketer

Parenteral Drugs India Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Dexon 4 mg Injection

Dexon 4 mg Injection is used to replace Dexamethasone deficiency. It treats various medical conditions, including severe allergic conditions, collagen diseases, pulmonary disorders, blood disorders, rheumatic diseases, skin diseases, gastrointestinal disorders, oedema, eye disorders, neoplastic states and endocrine disorders. It is also used in preoperative and postoperative support. Furthermore, it is approved for the treatment of coronavirus disease 2019 (COVID-19) in adult and adolescent patients (aged 12 years and older with a body weight of at least 40 kg) who require supplemental oxygen therapy.

Dexon 4 mg Injection contains dexamethasone, a steroid with both anti-inflammatory and immunosuppressant activity. Anti-inflammatory activity relieves the symptoms of inflammatory conditions, such as redness, swelling, and tenderness caused by various medical conditions. On the other side, immunosuppressant activity helps to calm your immune system. As a result, it can aid in autoimmune diseases such as rheumatoid arthritis, in which your immune system erroneously destroys your own tissues.

Dexon 4 mg Injection will be administered by a healthcare professional; do not self-administer. Some people may experience mood changes in personality, mental health problems, muscle weakness, increased appetite, irregular or absent menstrual periods, infections and infestations, impaired vision, difficulty falling asleep or staying asleep, heartburn, peptic ulcer, muscle weakness, nausea and injection site pain or redness as side effects of Dexon 4 mg Injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Let your doctor know before prescribing Dexon 4 mg Injection if you are allergic to any content of this medicine or sulphites. Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before receiving this medicine. Before obtaining the Dexon 4 mg Injection, notify your doctor about your medical history and any other medications you are currently taking to rule out any potentially harmful effects.

Uses of Dexon 4 mg Injection

Treatment of Allergic or inflammatory conditions and Covid-19

Medicinal Benefits

Dexon 4 mg Injection is a steroid (corticosteroids) medication. Corticosteroids occur naturally in the body and contribute to overall health and well-being. Increasing your body's corticosteroid levels (such as dexamethasone) is an effective strategy for treating various disorders involving inflammation. Dexon 4 mg Injection decreases inflammation, otherwise which might worsen your disease. You must take it daily to get the maximum benefits of Dexon 4 mg Injection.

Directions for Use

Dexon 4 mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dexon 4 mg Injection

  • Difficulty falling asleep or staying asleep

  • Mood changes in personality

  • Depression

  • Muscle weakness

  • Increased sweating

  • Increased appetite

  • Weight gain

  • Joint pain

  • Irregular or absent menstrual periods

  • Injection site pain or redness

  • Mental health problems

  • Infections and infestations

  • Abnormal growth of tissue

  • Abnormal increase in the number of white blood cells

  • Abnormal hair growth

  • Impaired vision

  • Vertigo (spinning sensation)

  • Headache

  • Cataracts or feeling increased pressure in the eye

  • Thickening of the heart muscle

  • High blood pressure

  • Blood clots in the veins

  • Nausea

  • Hiccups (sudden inspiration or intake of air)

  • Heartburn

  • Peptic ulcer

  • Muscle weakness

  • Loss of muscle mass

  • Osteoporosis (loss of bone density)

Drug Warnings

Before prescribing Dexon 4 mg Injection, inform your doctor if you are allergic to any content of this medicine or other steroid medicines. You should disclose to your doctor if you have received any live virus vaccines. You should discuss with your doctor if you have fungal infections, amoebiasis, myasthenia gravis, peptic ulcer, osteoporosis, psychoses, eye infections, glaucoma, mental conditions, TB, bacteraemia (viable bacteria in the bloodstream), joint, liver, kidney, or heart conditions and septic arthritis resulting from gonorrhoea or tuberculosis. If you are pregnant, planning for pregnancy or breastfeeding, inform your doctor before receiving this medicine. Contact your doctor immediately if you notice mood changes or have depression and strange thoughts while Dexon 4 mg Injection therapy.

Drug Interactions

Drug-Drug Interactions: Dexon 4 mg Injection may interact with nonsteroidal anti-inflammatory drugs (e.g. aspirin), anticonvulsants (e.g. phenytoin), sedative-hypnotic medications (e.g. phenobarbital, primidone), antibiotics (e.g. rifampicin, rifabutin), anticancer (e.g. aminoglutethimide), anticoagulant (e.g. warfarin), antiretroviral drugs (e.g. ritonavir, darunavir), and medicines used to treat epilepsy, pain and manic depression (e.g. carbamazepine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: If you ever had fungal infections, epilepsy, schizophrenia, amoebiasis, myasthenia gravis, peptic ulcer, osteoporosis, psychoses, eye infections, glaucoma, mental conditions, diabetes, TB, bacteraemia (viable bacteria in the bloodstream), joint, liver, kidney, or heart conditions and septic arthritis resulting from gonorrhoea or tuberculosis or have or had a recent vaccination inform your doctor before taking Dexon 4 mg Injection.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENYTOIN
  • PHENOBARBITAL
  • PRIMIDONE
  • RIFAMPICIN
  • RIFABUTIN
  • AMINOGLUTETHIMIDE
  • WARFARIN
  • RITONAVIR
  • DARUNAVIR
  • CARBAMAZEPINE

Habit Forming

No

Diet & Lifestyle Advise

Diet & Lifestyle for Allergic or inflammatory conditions:

  • Consume antioxidant-rich food. Blueberries, tomatoes, cherries, squash, and bell peppers are highly antioxidants.

  • Consuming probiotic-rich foods aids in the development of the immune system's resistance to allergies.

  • Consume foods rich in quercetin (a flavonoid), such as apples, cherries, spinach, broccoli, and blueberries.

  • Include seasonal fruits, vegetables, whole grains, healthy fats, and fish in your daily diet.

  • Limit your intake of foods that may cause allergies, such as dairy products, soy, eggs, and nuts.

  • Limit the consumption of foods high in sugar that may aggravate inflammation.

  • Reducing stress and having a regular sleep schedule might be beneficial.

  • Avoid processed meats, refined carbohydrates, sugar, trans fats, and alcohol, as they may aggravate inflammation.

 

Diet & Lifestyle for Covid-19:

  • Remember always to wear a mask when you're around other people. Wearing a mask aids in the prevention of illness spread.

  • Take care of your mental health. Fear and anxiety can hamper the immune system as well. Therapy, yoga, and meditation effectively allow the mind a state of peace.

  • Keep a social distance and avoid social gatherings.

  • Please do not touch your eyes, nose or mouth if your hands are not clean.

  • Hands should be washed with soap and water or an alcohol-based sanitiser on a regular basis.

  • All surfaces should be cleaned and disinfected on a regular basis.

  • Gargling with salt water and inhaling steam would be beneficial.

  • Never exchange personal objects that have been contaminated with bodily fluids or blood, such as razor blades or toothbrushes.

  • Never share used needles and other injections or medical devices, as they may spread viruses.

  • Consume a well-balanced diet. Consume vitamin and nutrient-rich foods like dark green, yellow, orange, and red vegetables and fruits to enhance your immune system. Choose lean protein and whole carbohydrates over-processed foods.

  • Consume no raw meat or eggs. Consume boiled and cooked meat, poultry, or seafood.

  • If you have nausea or vomiting, eat bland, low-fat foods and avoid spicy or greasy foods.

  • Spending time with family or doing whatever makes you happy might help you minimise emotional and physical stress.

Special Advise

  • Dexon 4 mg Injection may affect various laboratory tests. Therefore, inform your doctor/lab technician, that you are on treatment with Dexon 4 mg Injection if you are undergoing any tests.

Disease/Condition Glossary

Allergy: Allergy is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as 'allergens.' Allergic condition varies from person to person. Some might be allergic to certain foods, medications, and seasonal allergies like hay fever, pollen, or pet dander. The symptoms of an allergic reaction include itching, rash, scratchy throat, itchy or watery eyes, hives or itchy red spots on the skin, or allergic rhinitis (which causes sneezing or nasal congestion).

Inflammation: It is a response generated by damage to living tissues. This response is a defence mechanism to protect the body from injury, infection, or disease. The symptoms of inflammation include redness, pain, swelling, heat, or loss of function. Inflammation can be caused by certain medications, acute and chronic conditions, exposure to foreign materials or irritants your body can't eliminate easily. 

Coronavirus disease (COVID-19): Covid-19 is an infectious disease caused by the SARS-CoV-2 virus. Most persons who become ill with Covid-19 will have mild to moderate symptoms and recover without specific therapy. Some, though, will become extremely unwell and require medical assistance. The virus can spread from an infected person's mouth or nose in microscopic liquid particles when they cough, sneeze, speak, sing, or breathe. Fever, cough, tiredness, and loss of taste or smell are the most common side effects of Covid-19.

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Alcohol

Caution

It is unknown whether alcohol interacts with Dexon 4 mg Injection. Please consult your doctor.

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Pregnancy

Caution

If you are pregnant, inform your doctor. Your doctor will then decide if the Dexon 4 mg Injection is suitable for you. Your doctor may prescribe this medicine only if the benefits outweigh the risks.

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Breast Feeding

Caution

Inform your doctor if you are a nursing mother. The doctor will then decide if the injection is suitable for you. Your doctor may prescribe this medicine only if the benefits outweigh the risks.

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Driving

Caution

Dexon 4 mg Injection may cause a reduction in mental awareness; thus, avoid operating machinery or driving.

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Liver

Caution

Inform your doctor before receiving the Dexon 4 mg Injection if you have a history of or ongoing liver disease. Your doctor will adjust the dose of this medicine if required based on your condition.

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Kidney

Caution

Inform your doctor before receiving the Dexon 4 mg Injection if you have a history of or ongoing kidney disease. Your doctor may carry out extra checks while you are taking this medicine.

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Children

Caution

Dexon 4 mg Injection may affect the growth of children. Therefore, your doctor may check the growth of the child regularly while using the Dexon 4 mg Injection.

Country of origin

India

Manufacturer/Marketer address

Shree Ganesh Chambers, Navlakha Crossing, A.B. Road, Indore 452001 Mandhya Pradesh (India)
Other Info - DEX0356

Author Details

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FAQs

Dexon 4 mg Injection is used in conditions like severe allergy, collagen diseases, pulmonary disorders, blood disorders, rheumatic diseases, skin diseases, gastrointestinal disorders, oedema, eye disorders, neoplastic states and endocrine disorders.
Dexon 4 mg Injection contains dexamethasone, a steroid with both anti-inflammatory and immunosuppressant activity. Anti-inflammatory activity relieves the symptoms of inflammatory conditions such as redness, swelling, and tenderness caused by various medical conditions. On the other side, immunosuppressant activity helps to calm your immune system. As a result, it can aid in autoimmune diseases such as rheumatoid arthritis, in which your immune system erroneously destroys your own tissues.
If you are about to be vaccinated, especially if it is a live vaccine, inform your doctor that you are taking Dexon 4 mg Injection because taking Dexon 4 mg Injection and getting immunised at the same time is not recommended.
Dexon 4 mg Injection is not recommended to be used in fungal infections. If you have any concerns regarding this, please discuss them with your doctor.
Dexon 4 mg Injection may increase the risk of Infections and infestations. Therefore, it is advised to stay away from people having chickenpox (herpes simplex), shingles (herpes zoster) or measles.
Dexon 4 mg Injection is approved for the treatment of coronavirus disease 2019 (COVID-19) in adults and adolescents (aged 12 years and older with a body weight of at least 40 kg) who require supplemental oxygen therapy.
Caution is advised if you are taking anticoagulants while on Dexon 4 mg Injection treatment. Checking your blood clotting time is recommended to lessen the risk of bleeding.
Dexon 4 mg Injection should not be used in patients with systemic fungal infections, allergies to dexamethasone, or any other ingredients of medicine or patients who received live vaccines recently.
Dexon 4 mg Injection may cause side effects such as depression, muscle weakness, increased sweating, increased appetite, weight gain, joint pain, irregular menstrual periods, mental health problems, impaired vision, headache, nausea, high blood pressure, heart burns, peptic ulcers, and blood clots in veins. If these side effects persist or worsen, please consult your doctor.
Dexon 4 mg Injection may interact with other medicines such as phenytoin (anticonvulsants), aspirin (nonsteroidal anti-inflammatory drugs), rifampicin (antibiotic), warfarin (anticoagulant), ritonavir (antiretroviral drugs), and aminoglutethmide (anticancer). Therefore, consult your doctor before taking other medicines while on treatment with Dexon 4 mg Injection.
Store Dexon 4 mg Injection at room temperature. Protect from light. Keep it out of reach of children.
It is essential to regularly monitor your blood sugar levels, electrolytes, blood pressure, and bone density if you are using Dexon 4 mg Injection for long-term. Discuss with doctor for any further information.

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