What is the use of Develprin ER 500 mg Tablet ?

Develprin ER 500 mg Tablet is used to treat epilepsy/seizures/fits. In addition, it also helps treat manic episodes associated with bipolar disorder and prevent migraine symptoms (like a headache).

How does Develprin ER 500 mg Tablet help to control seizures?

Develprin ER 500 mg Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Is Develprin ER 500 mg Tablet used to treat bipolar disorder?

Develprin ER 500 mg Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Does Develprin ER 500 mg Tablet help in preventing migraine?

Develprin ER 500 mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.

Does Develprin ER 500 mg Tablet cause weight gain?

Develprin ER 500 mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

I am planning for pregnancy. Is it safe to take Develprin ER 500 mg Tablet ?

Use an effective method of contraception during the treatment with Develprin ER 500 mg Tablet . Avoid getting pregnant while taking Develprin ER 500 mg Tablet as it could lead to serious birth defects. Do not stop taking Develprin ER 500 mg Tablet and consult your doctor immediately if you become pregnant.

Does prolonged intake of Develprin ER 500 mg Tablet causes weight gain?

Develprin ER 500 mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

What are the side effects of Develprin ER 500 mg Tablet ?

Develprin ER 500 mg Tablet may cause common side effects such as nausea, vomiting, headache, sleepiness, tremor, weakness, dizziness, stomach pain, and weight gain. If these side effects persist or worsen, please consult your doctor.

What does Develprin ER 500 mg Tablet contain?

Develprin ER 500 mg Tablet contains Valproic acid as its active ingredient.

When should I take Develprin ER 500 mg Tablet ?

Take Develprin ER 500 mg Tablet with or without food as advised by your doctor.

Does Develprin ER 500 mg Tablet cause an addiction?

No, Develprin ER 500 mg Tablet does not cause addiction. However, Develprin ER 500 mg Tablet should be used as per dose and duration prescribed by your doctor. Do not self-medicate.

For how long should I take Develprin ER 500 mg Tablet to cure my epilepsy completely?

Develprin ER 500 mg Tablet does not cure epilepsy, it only helps to prevent the seizures. However, you have to take Develprin ER 500 mg Tablet for as long as it is advised by your doctor. If you face any difficulty while taking Develprin ER 500 mg Tablet , consult your doctor.

What happens if I stop taking Develprin ER 500 mg Tablet ?

If you stop taking Develprin ER 500 mg Tablet suddenly, it may increase the risk of recurrence of seizures. Therefore, it should be stopped gradually. If you feel the need to stop taking Develprin ER 500 mg Tablet , please consult your doctor.

Does Develprin ER 500 mg Tablet affect the working of birth control pills?

Some birth control pills (oestrogen-containing birth control pills) may lower the levels of Develprin ER 500 mg Tablet in blood. Thus, inform your doctor if you are using birth control pills and discuss with your doctor about the suitable method of contraception.

Is it safe to take Develprin ER 500 mg Tablet for long term?

Develprin ER 500 mg Tablet is safe to take for long time in many patients if prescribed by a doctor. In rare cases, prolonged use of Develprin ER 500 mg Tablet may weaken your bones, thereby increasing their risk of breaking easily (osteopenia and osteoporosis). Get regular checkups done for bone health if you are taking Develprin ER 500 mg Tablet for a long time.

I am concerned because I have heard that Develprin ER 500 mg Tablet causes hair loss. Is it true?

Develprin ER 500 mg Tablet may cause hair thinning, hair colour changes and even hair loss. If you have any concerns regarding this, please ask your doctor if it is possible to lower the dose of Develprin ER 500 mg Tablet . Your hair may regrow after either lowering your dose or changing medication.

Develprin ER 500 mg Tablet 10's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Develprin ER 500 mg Tablet is used to treat seizures. Besides this, it is also used to treat manic episodes associated with bipolar disorder and prevent migraine symptoms. It contains Valproic acid which works by reducing abnormal electrical activity in the brain. It also produces a calming effect and limits the transmission of pain signals. This medicine may sometimes cause side effects such as nausea, upset stomach, tremors, sleepiness, headache, and weight gain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About Develprin ER 500 mg Tablet

Develprin ER 500 mg Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. In addition, Develprin ER 500 mg Tablet also treats manic episodes associated with bipolar disorder. Besides this, it can also prevent migraine symptoms (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

Develprin ER 500 mg Tablet contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Develprin ER 500 mg Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Develprin ER 500 mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Develprin ER 500 mg Tablet should be taken as prescribed by the doctor. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects are temporary and will go away on their own. However, if you suffer these adverse effects on a regular basis, you should consult your doctor.

Inform your doctor if you are allergic to any components present in Develprin ER 500 mg Tablet . If you are pregnant, do not take Develprin ER 500 mg Tablet because it may cause serious congenital defects. Use effective contraception if you are of childbearing age while taking Develprin ER 500 mg Tablet . If you are breastfeeding, inform your doctor before taking Develprin ER 500 mg Tablet . As Develprin ER 500 mg Tablet causes sleepiness and dizziness, do not drive or operate machinery. Avoid drinking alcohol with Develprin ER 500 mg Tablet as it may cause dizziness and tiredness. To rule out any negative effects, keep your doctor updated about your health condition and medications.

Uses of Develprin ER 500 mg Tablet

Develprin ER 500 mg Tablet is used for the treatment of Epilepsy (fits), Bipolar disorder, Migraine.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Develprin ER 500 mg Tablet contains Valproic acid, an anticonvulsant (or anti-epileptic) medicine that reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Develprin ER 500 mg Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Develprin ER 500 mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

How Develprin ER 500 mg Tablet Works

Develprin ER 500 mg Tablet contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Develprin ER 500 mg Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Develprin ER 500 mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Develprin ER 500 mg Tablet

Stomach pain
Feeling or being sick
Diarrhoea
Dry or sore mouth or swollen gums
Shakes (tremors) in a part of your body
Unusual eye movements
Feeling tired or sleepy
Headache
Weight gain
Thinning hair, or changes to the colour or texture of your hair
Irregular or delayed periods

What if I have taken an overdose of Develprin ER 500 mg Tablet

Take Develprin ER 500 mg Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include sleepiness, irregular heartbeat, and coma (loss of consciousness for a period of time). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Before taking the Develprin ER 500 mg Tablet , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding. You should not become pregnant while you are receiving Develprin ER 500 mg Tablet . Consult your doctor immediately if you become pregnant while receiving a Develprin ER 500 mg Tablet . Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Develprin ER 500 mg Tablet .

Drug-Drug Interactions

Sodium ValproateSodium phenylbutyrate

Critical

Sodium ValproateVorinostat

Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate

Critical

How does the drug interact with Develprin ER 500 mg Tablet 10's:
Combining Sodium phenylbutyrate and Develprin ER 500 mg Tablet 10's can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Develprin ER 500 mg Tablet 10's is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Sodium ValproateVorinostat

Severe

How does the drug interact with Develprin ER 500 mg Tablet 10's:
Co-administration of Vorinostat with Develprin ER 500 mg Tablet 10's can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Develprin ER 500 mg Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Sodium ValproateTeriflunomide

Severe

How does the drug interact with Develprin ER 500 mg Tablet 10's:
Co-administration of Teriflunomide and Develprin ER 500 mg Tablet 10's can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Develprin ER 500 mg Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Sodium ValproateDoripenem

Severe

How does the drug interact with Develprin ER 500 mg Tablet 10's:
Co-administration of Develprin ER 500 mg Tablet 10's with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Develprin ER 500 mg Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Sodium ValproateErtapenem

Severe

How does the drug interact with Develprin ER 500 mg Tablet 10's:
The combined use of Ertapenem and Develprin ER 500 mg Tablet 10's can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Develprin ER 500 mg Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.

Sodium ValproateBuprenorphine

Severe

How does the drug interact with Develprin ER 500 mg Tablet 10's:
Using buprenorphine together with Develprin ER 500 mg Tablet 10's may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Develprin ER 500 mg Tablet 10's can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Sodium ValproateMeropenem

Severe

How does the drug interact with Develprin ER 500 mg Tablet 10's:
Co-administration of Meropenam and Develprin ER 500 mg Tablet 10's together can reduce the effect of Develprin ER 500 mg Tablet 10's.

How to manage the interaction:
Co-administration of Meropenam and Develprin ER 500 mg Tablet 10's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Sodium ValproateKetamine

Severe

How does the drug interact with Develprin ER 500 mg Tablet 10's:
Co-administration of Ketamine and Develprin ER 500 mg Tablet 10's can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Develprin ER 500 mg Tablet 10's can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.

Sodium ValproateLeflunomide

Severe

How does the drug interact with Develprin ER 500 mg Tablet 10's:
Co-administration of Leflunomide and Develprin ER 500 mg Tablet 10's can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Develprin ER 500 mg Tablet 10's can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Sodium ValproateLithium

Severe

How does the drug interact with Develprin ER 500 mg Tablet 10's:
Co-administration of Lithium with Develprin ER 500 mg Tablet 10's can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Develprin ER 500 mg Tablet 10's can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Adolescents and adults are advised to follow the Atkins diet (high fat, low carbohydrate).
Exercising on a regular basis aids with weight maintenance and general health.
Rest well, and get plenty of sleep.
Avoid smoking and drinking alcohol.
Meditation and yoga can help reduce stress, reduce pain sensitivity, and increase coping abilities.
Have a seizure response plan in place, and make sure everyone around you knows what to do in the event of a seizure.
Prepare your living environment; simple changes may help reduce the risk of physical damage during a seizure.
Understand what causes seizures and try to reduce or avoid them.
Please keep your overall health in mind, as it can aid in the reduction of seizure activity.
Install an alarm or an emergency gadget to summon help during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Develprin ER 500 mg Tablet Substitute

Valeptol Solution 100 ml
₹0.65per tablet
Cotwel-Cr 200Mg Tablet 10'S
by AYUR
₹4.05per tablet
Alporate 200Mg Syp 200Ml
by AYUR
₹0.55per tablet
Cognirex-Od 250Mg Tablet
by AYUR
₹4.23per tablet
Dilpra 250Mg Tablet
by AYUR
₹3.96per tablet

Alcohol

Caution

Do not consume alcohol while taking Develprin ER 500 mg Tablet as alcohol can worsen the side effects of the Develprin ER 500 mg Tablet , including sleepiness and dizziness.

Pregnancy

Unsafe

Develprin ER 500 mg Tablet is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Develprin ER 500 mg Tablet .

Breast Feeding

Caution

Develprin ER 500 mg Tablet passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Develprin ER 500 mg Tablet . Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

Driving

Caution

Develprin ER 500 mg Tablet may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Develprin ER 500 mg Tablet .

Liver

Caution

Inform your doctor before receiving the Develprin ER 500 mg Tablet if you have a history of liver diseases/conditions. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Develprin ER 500 mg Tablet .

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

Children

Consult your doctor

Use is not recommended for children less than ten years. Your doctor will decide the dose based on your child's condition if more than ten years.

FAQs

Country of origin

India

Manufacturer/Marketer address

A-13, Iris Tech Park, Sector 48, Sohna Road, Gurugram - 122018, Haryana, India.

Other Info - DEV0049

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Drug-Drug Interactions

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Develprin ER 500 mg Tablet Substitute

Valeptol Solution 100 ml

Cotwel-Cr 200Mg Tablet 10'S

Alporate 200Mg Syp 200Ml

Cognirex-Od 250Mg Tablet

Dilpra 250Mg Tablet

Valeptol Solution 100 ml

Cotwel-Cr 200Mg Tablet 10'S

Alporate 200Mg Syp 200Ml

Cognirex-Od 250Mg Tablet

Dilpra 250Mg Tablet

Valpotex-CR 200mg Tablet 10's

Dilex OD 250mg Tablet 10's

Divex ER 250 Tablet 10's

CHRONO 200MG TABLET

Megprate CR 200 Tablet 10's

Sovalmat CR 200 Tablet 10's

Nevapil Chrono 200mg Tablet

Novalept Chrono 200mg Tablet CR

Valcorex CR-200 Tablet 10's

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