Desifer 400 mg Tablet is used for treating chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients two years older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

The active ingredient in Desifer 400 mg Tablet is deferasirox. It is a trivalent iron selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

Desifer 400 mg Tablet is available in the form of oral formulations. Please take Desifer 400 mg Tablet in the dose and duration prescribed by your doctor based on specific medical conditions. In some cases, you may experience common side effects such as diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue using Desifer 400 mg Tablet for as long as your doctor has prescribed it. Do not use Desifer 400 mg Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Desifer 400 mg Tablet if you are pregnant or breastfeeding. Do not use Desifer 400 mg Tablet in more than prescribed doses or for a longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Desifer 400 mg Tablet to rule out any side effects.

Deferasirox is the active component in Desifer 400 mg Tablet. It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

• Diarrhea

• Vomiting
• Nausea
• Abdominal Pain
• Skin Rashes
• Increases in Serum Creatinine

Do not take Desifer 400 mg Tablet if you are allergic to Desifer 400 mg Tablet or its ingredients. Desifer 400 mg Tablet is not usually recommended if you are a pregnant or lactating woman; there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the medicine's benefits outweigh the risks. It is unknown whether Desifer 400 mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer. Avoid consuming alcohol along with Desifer 400 mg Tablet as it could lead to unpleasant side effects. Should monitor elderly and paediatric patients closely for toxicity.

Drug-Drug interactions: Desifer 400 mg Tablet may interact with aluminium-containing antacids (e.g. aluminium hydroxide, aluminium glycinate), anti-diabetic drugs (e.g. repaglinide), xanthines (e.g. theophylline), alkylating agents (e.g. busulfan), nonsteroidal anti-inflammatory drugs (e.g. aspirin, celecoxib) and antihypertensive drugs (e.g. diltiazem), and common painkiller (e.g. paracetamol).

Drug-Food Interactions: Avoid consuming alcohol and caffeine along with Desifer 400 mg Tablet.

Drug-Disease Interactions: People affected with bone marrow suppression, dermatologic toxicities, hepatic impairment, renal dysfunction, auditory and ocular abnormalities, and GI complication should consult the doctor before taking Desifer 400 mg Tablet.

• ALUMINIUM HYDROXIDE
• REPAGLINIDE
• THEOPHYLLINE
• BUSULFAN
• ASPIRIN
• CELECOXIB
• DILTIAZEM
• PARACETAMOL

• Choose foods high in nutrients, such as fruits, vegetables, and whole grains.

• Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved well-being.

• Create a diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

• Instead of saturated and trans fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).

• Select/prepare foods and beverages with fewer added sugars/caloric sweeteners.

• Be mindful of salt; consume no more than 2,300 mg each day.

• Limit or avoid alcohol and caffeine consumption.

• Monitor blood counts, liver function, and renal function monthly.

• Monitor serum ferritin monthly to assess the patient’s response to therapy and minimize the risk of over-chelation.

Hemochromatosis, or iron overload, is a condition in which your body stores too much iron. It can cause severe damage to your body, including to your heart, liver and pancreas.