apollo
0
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Depsonil 25 Tablet is used to treat depression. It contains Imipramine which increases the activity of certain natural substances (neurotransmitters) which regulate mood. Additionally, it is also used to treat bed-wetting at night in children aged 6 years and older by relaxing the urinary bladder muscles. This medicine may sometimes cause side effects such as dry mouth, nausea, vomiting, increased blood pressure, lack of coordination, swelling of the breast and weakness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
Read more
rxMedicinePrescription drug

Whats That

tooltip
socialProofing20 people bought
in last 30 days
Consult Doctor

Composition :

IMIPRAMINE-25MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Depsonil 25 Tablet

Depsonil 25 Tablet belongs to a group of medicines called 'tricyclic anti-depressants' used to treat depression. Additionally, Depsonil 25 Tablet is also used to treat bed-wetting at night in children aged 6 years and older. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.
 
Depsonil 25 Tablet contains ‘Imipramine’, which increases the activity of certain natural substances (neurotransmitters) in the brain required for mental balance, thereby regulating mood and treating depression. It also reduces childhood enuresis or bed-wetting in the children older than 6-7 years of age by relaxing the urinary bladder muscle, which lightens the sleep.
 
You are advised to take Depsonil 25 Tablet for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as dry mouth, nausea, vomiting, increased blood pressure, lack of coordination, swelling of the breast and weakness.  You are advised to talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking Depsonil 25 Tablet without consulting your doctor as it could lead to withdrawal symptoms. Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating machinery as Depsonil 25 Tablet may cause impaired alertness, drowsiness or blurred vision. Depsonil 25 Tablet is not recommended for children below 6 years as safety and effectiveness have not been established. Avoid consuming alcohol with Depsonil 25 Tablet as it could lead to increased drowsiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Depsonil 25 Tablet

Treatment of Depression, Nocturnal enuresis (bed-wetting in children)

Directions for Use

Swallow Depsonil 25 Tablet as a whole with a glass of water, do not chew or crush it.

Medicinal Benefits

Depsonil 25 Tablet belongs to a group of medicines called tricyclic anti-depressants. Depsonil 25 Tablet is used to treat depression. Depsonil 25 Tablet works by increasing the activity of certain natural substances in the brain needed for mental balance, thereby regulating mood and treating depression. Additionally, Depsonil 25 Tablet is used as an adjunct therapy in reducing bed-wetting at night in children aged 6-7 years and older. Depsonil 25 Tablet helps to control childhood enuresis or bed-wetting as a part of its anti-depressant effect.

How Depsonil 25 Tablet Works

Depsonil 25 Tablet contains ‘Imipramine’, which increases the activity of certain natural substances (neurotransmitters) in the brain required for mental balance, thereby regulating mood and treating depression. It also reduces childhood enuresis or bed-wetting in the children older than 6-7 years of age by relaxing the urinary bladder muscle, which lightens the sleep.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Depsonil 25 Tablet

  • Dry mouth
  • Nausea
  • Vomiting
  • Increased blood pressure
  • Lack of coordination
  • Swelling of breast
  • Weakness
  • Trouble urinating
  • Blurred vision
  • Breast swelling in men and women

What if I have taken an overdose of Depsonil 25 Tablet

Take Depsonil 25 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include feeling like you might pass out, irregular heartbeats, seizures, or coma. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Depsonil 25 Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days, if you have heart diseases, mania, porphyria, glaucoma or are unable to pass urine. Avoid taking buprenorphine/opioids with Depsonil 25 Tablet as it could lead to serotonin syndrome. Inform your doctor if you have/had schizophrenia or manic depression, alcohol withdrawal, enlarged prostate, overactive thyroid, epilepsy, low blood pressure, poor circulation, panic attacks, a tumour of the adrenal gland, or if you are being given electroconvulsive therapy. Talk to your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating machinery as Depsonil 25 Tablet may cause impaired alertness, drowsiness, or blurred vision. Depsonil 25 Tablet is not recommended for children below 6 years as safety and effectiveness have not been established. Avoid consuming alcohol with Depsonil 25 Tablet as it could lead to increased drowsiness. Rise slowly from sitting or lying position as Depsonil 25 Tablet causes dizziness on standing suddenly.

Drug-Drug Interactions

verifiedApollotooltip
ImipramineSparfloxacin
Critical
ImipraminePhenelzine
Critical

Drug-Drug Interactions

Login/Sign Up

ImipramineSparfloxacin
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
Taking Sparfloxacin with Depsonil 25 Tablet 10's can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sparfloxacin and Depsonil 25 Tablet 10's together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipraminePhenelzine
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
Coadministration of Depsonil 25 Tablet 10's with Phenelzine might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Depsonil 25 Tablet 10's and Phenelzine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineLinezolid
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
Coadministration of Linezolid with Depsonil 25 Tablet 10's might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Linezolid and Depsonil 25 Tablet 10's together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineDronedarone
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
Taking Depsonil 25 Tablet 10's with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Depsonil 25 Tablet 10's with Dronedarone together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineZiprasidone
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
Using ziprasidone together with Depsonil 25 Tablet 10's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Depsonil 25 Tablet 10's is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
ImipraminePotassium citrate
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
Taking Depsonil 25 Tablet 10's and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Potassium citrate and Depsonil 25 Tablet 10's is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ImipramineTranylcypromine
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
Taking Tranylcypromine can increase the risk of Depsonil 25 Tablet 10's on serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Depsonil 25 Tablet 10's is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
ImipramineSafinamide
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
Coadministration of Safinamide with Depsonil 25 Tablet 10's can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking safinamide and Depsonil 25 Tablet 10's together is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
ImipramineThioridazine
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
When Thioridazine and Depsonil 25 Tablet 10's are taken together, the body's ability to break down Thioridazine may be reduced. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Depsonil 25 Tablet 10's with Thioridazine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience extreme drowsiness, confusion, agitation, vomiting, blurred vision, feeling hot or cold, sweating, muscle stiffness, fainting, or seizure, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineSelegiline
Critical
How does the drug interact with Depsonil 25 Tablet 10's:
Co-administration of Depsonil 25 Tablet 10's with Selegiline might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Depsonil 25 Tablet 10's and Selegiline together is not recommended as it can result in an interaction. It can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improves mood, boosts self-esteem and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Depsonil 25 Tablet Substitute

Substitutes safety advice
  • Antidep Tablet 10's

    1.53per tablet
  • DEPSOL 25MG TABLET

    1.35per tablet
  • DEPRANIL 25MG TABLET

    1.22per tablet
  • DEPRID 25MG TABLET

    0.86per tablet
  • Dimip 25mg Tablet 10's

    by AYUR

    1.17per tablet
bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Depsonil 25 Tablet as it may cause increased drowsiness.

bannner image

Pregnancy

Caution

Depsonil 25 Tablet belongs to pregnancy category C. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Depsonil 25 Tablet may pass into breastmilk. Consult your doctor before taking Depsonil 25 Tablet ; your doctor will decide whether Depsonil 25 Tablet can be taken by breastfeeding mothers or not.

bannner image

Driving

Unsafe

Depsonil 25 Tablet may cause impaired alertness, drowsiness or blurred vision. Do not drive or operate machinery if you experience these symptoms.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Depsonil 25 Tablet is not recommended for children below 6 years as its safety and effectiveness have not been established.

FAQs

Depsonil 25 Tablet is used to treat depression. Additionally, it is also used to treat bed-wetting at night in children aged 6 years and older.
Depsonil 25 Tablet works by increasing mood-enhancing chemical messengers (neurotransmitters) such as serotonin and norepinephrine in the brain that communicate between brain cells, thereby regulating mood and treating depression.
Do not discontinue Depsonil 25 Tablet without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking Depsonil 25 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Depsonil 25 Tablet . The doctor may reduce the dose gradually to prevent withdrawal symptoms.
Dry mouth could be a side-effect of Depsonil 25 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Orthostatic hypotension could be a side-effect of Depsonil 25 Tablet . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead, lie down and get up slowly only when you feel better.
Depsonil 25 Tablet may cause photosensitivity or increased sensitivity to sunlight. Therefore, people taking Depsonil 25 Tablet should avoid excessive exposure to sunlight or tanning beds. Use effective sunscreen and wear protective clothing while going outside.
Consult your doctor before taking Depsonil 25 Tablet if you are diabetic, as Depsonil 25 Tablet may cause elevation or lower blood glucose levels. Regularly monitor blood sugar levels while taking Depsonil 25 Tablet .
Depsonil 25 Tablet may make your open-angle glaucoma worse. Your doctor may monitor your vision while you’re taking this medication.
Depsonil 25 Tablet may affect blood sugar levels, especially in people with diabetes. It can cause fluctuations in blood sugar, so it's important to monitor your levels closely and consult your doctor for personalized advice.
Depsonil 25 Tablet may cause weight gain in some people as it is an antidepressant that works by blocking certain neurotransmitters. This can lead to increased appetite and changes in metabolism, resulting in weight gain. Monitor your weight and discuss any changes with your doctor. They can adjust your medication or suggest lifestyle changes to manage this side effect.
Depsonil 25 Tablet is not an addictive or habit-forming medication.
The common side effects of Depsonil 25 Tablet you may experience are dry mouth, nausea, vomiting, increased blood pressure, lack of coordination, swelling of the breast, and weakness. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
No, you should not stop taking Depsonil 25 Tablet suddenly without consulting your doctor. Stopping abruptly can lead to withdrawal symptoms like nervousness, anxiety, and irritability.
Depsonil 25 Tablet belongs to pregnancy category C medication, meaning it may be harmful to a fetus. Please consult your doctor before taking Depsonil 25 Tablet if you plan to become pregnant or are already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Depsonil 25 Tablet .
Store Depsonil 25 Tablet in a cool, dry place away from sunlight. Keep it out of reach of children.
Depsonil 25 Tablet may cause drowsiness or sleepiness, especially when first starting the medication or increasing the dosage. This sedative effect may decrease as your body adjusts to the medication. If it is not, consult the doctor.
If you forget a dose of Depsonil 25 Tablet , take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - DEP0032

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button