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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Depsone 100mg Tablet is used to treat leprosy (Hansen's disease), dermatitis herpetiformis (a skin problem), and Actinomycotic mycetoma (a fungal disease). It is also used to prevent malaria and pneumonia. It contains Dapsone, which works by inhibiting the growth or killing bacteria or fungi that cause infection. Common side effects of Depsone 100mg Tablet are haemolysis (destruction of red blood cells), tiredness, shortness of breath, or a bluish tinge to the skin.
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Composition

DAPSONE-100MG

Manufacturer/Marketer

Hul Nutrition

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Depsone 100mg Tablet

Depsone 100mg Tablet belongs to the class of anti-infectives used to treat leprosy (Hansen's disease), dermatitis herpetiformis (a skin problem) and Actinomycotic mycetoma (a fungal disease). Also, it is used in the prevention of malaria and pneumonia. Leprosy is an infectious disease that causes skin lesions and nerve damage.

Depsone 100mg Tablet contains Dapsone which works by inhibiting the growth or killing bacteria or fungi that cause infection. 

Take Depsone 100mg Tablet as prescribed. You are advised to use Depsone 100mg Tablet for as long as your doctor has recommended based on your medical condition. In some cases, you may experience haemolysis (destruction of red blood cells), tiredness, shortness of breath or a bluish tinge to the skin. Most of these side effects of Depsone 100mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Dapsone, sulpha drugs or any other medicines, please inform your doctor. You are recommended to consult your doctor if you are pregnant or planning for pregnancy before taking Depsone 100mg Tablet. Depsone 100mg Tablet is not recommended for breastfeeding mothers as it may cause blood problems in nursing babies. If you get shortness of breath, weakness, back pain, tiredness, dark brown urine, fever, pale or yellow skin, stop using Depsone 100mg Tablet and consult a doctor immediately as they might be symptoms of haemolytic anaemia (breakdown of red blood cells). This condition usually occurs in people with glucose 6-phosphate dehydrogenase (G6PD) deficiency using Depsone 100mg Tablet.

Uses of Depsone 100mg Tablet

Treatment of Leprosy and Skin problems

Medicinal Benefits

Depsone 100mg Tablet contains Dapsone (anti-infective) used to treat leprosy (Hansen's disease), dermatitis herpetiformis (a skin problem) and Actinomycotic mycetoma (a fungal disease). Dapsone works by inhibiting the growth or killing bacteria or fungi that cause infection. Also, Depsone 100mg Tablet may be used in the prevention of malaria when used in combination with pyrimethamine and the prevention of pneumonia in immunodeficient patients, especially in AIDS patients.

Directions for Use

Take this medicine with or without food or as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Depsone 100mg Tablet

  • Haemolysis (destruction of red blood cells)
  • Tiredness
  • Shortness of breath
  • Bluish tinge to the skin

Drug Warnings

If you are allergic to Dapsone, sulpha drugs or any other medicines, please tell your doctor. You are recommended to consult a doctor if you are pregnant or planning for pregnancy before taking Depsone 100mg Tablet. Depsone 100mg Tablet is not recommended for breastfeeding mothers as it may cause blood problems in nursing babies. If you get shortness of breath, weakness, back pain, tiredness, dark brown urine, fever, pale or yellow skin, stop using Depsone 100mg Tablet and consult a doctor immediately as they might be symptoms of haemolytic anaemia (breakdown of red blood cells). This condition usually occurs in people with glucose 6-phosphate dehydrogenase (G6PD) deficiency using Depsone 100mg Tablet. If you are about to take an oral typhoid vaccine, inform your doctor that you are taking Depsone 100mg Tablet as it may not be effective.

Drug Interactions

Drug-Drug Interaction: Inform your doctor if you are taking gout medicine (probenecid), antibiotics (trimethoprim, rifabutin, rifampicin), oral typhoid vaccine, anti-HIV drugs (amprenavir, didanosine), anti-tubercular agents (clofazimine), stomach acid reducer (cimetidine), antiparasitic drug (pyrimethamine), and anti-malarial drugs (chloroquine, primaquine).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have severe anaemia, porphyria (blood disorder), or other blood disorders, glucose 6-phosphate dehydrogenase (G6PD) deficiency, heart, liver, kidney or lung disease, please inform your doctor before taking Depsone 100mg Tablet. 

Drug-Drug Interactions Checker List

  • PROBENECID
  • TRIMETHOPRIM
  • RIFABUTIN
  • RIFAMPICIN
  • TYPHOID VACCINE
  • AMPRENAVIR
  • DIDANOSINE
  • CLOFAZIMINE
  • CIMETIDINE
  • PYRIMETHAMINE
  • CHLOROQUINE
  • PRIMAQUINE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat broccoli, spinach, spirulina and goji berries.
  • Include soy foods such as soy protein, soy milk and soy isolates as they are a good source of zinc.
  • Eat fish as it is the richest source of omega-3 fatty acids which prevents the skin from dryness.

Disease/Condition Glossary

Leprosy: Leprosy also known as Hansen's disease is an infectious disease that causes skin lesions and nerve damage. It mainly affects the eyes, skin, nose and peripheral nerves. The symptoms include red or light-coloured skin patches with reduced sensation, weakness and numbness in the feet and hands.

Dermatitis herpetiformis: It is a chronic (long-term) condition that causes itchy, blistering and burning skin rash as a result of gluten sensitivity. Gluten is found in common foods such as barley, rye and wheat. The rash and itching occur on the knees, elbows, buttocks, back, and scalp.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Depsone 100mg Tablet as it may worsen the side effects of Depsone 100mg Tablet.

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Pregnancy

Consult your doctor

Depsone 100mg Tablet is not recommended for use during pregnancy unless your doctor prescribes it. Therefore, please inform your doctor if you are pregnant or planning pregnancy before taking Depsone 100mg Tablet.

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Breast Feeding

Unsafe

Dapsone may pass into breast milk. Therefore, it is recommended to avoid breastfeeding while taking Depsone 100mg Tablet or discontinue using Depsone 100mg Tablet while breastfeeding as this medicine may cause blood disorders in the babies. Hence, please inform your doctor if you are breastfeeding before taking Depsone 100mg Tablet.

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Driving

Safe if prescribed

Depsone 100mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Depsone 100mg Tablet with caution, if you have a history of liver diseases/conditions. Your doctor may adjust the dose of this medicine if necessary based on your condition.

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Kidney

Caution

Take Depsone 100mg Tablet with caution, if you have a history of kidney diseases/conditions. Your doctor may adjust the dose of this medicine if necessary based on your condition.

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Children

Caution

Children under the age of six should not use Depsone 100mg Tablet because its safety and efficacy have not been proven. Typically, for kids older than 6 years, the dose is determined by the child's weight.

Country of origin

INDIA

Manufacturer/Marketer address

24-25 Floor, One Horizon Center Golf Course Road, DLF Phase 5 Gurgaon 122002, India
Other Info - DEP0074

Author Details

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FAQs

Depsone 100mg Tablet is used to treat Leprosy and Skin problems.
Depsone 100mg Tablet contains Dapsone, an anti-infective that works by inhibiting the growth or killing bacteria or fungi that cause infection.Â
Depsone 100mg Tablet may cause methemoglobinemia (a serious condition that occurs when the oxygen amount in the blood decreases severely) as a side effect. It is not necessary for everyone using Depsone 100mg Tablet to experience this side effect. However, if you notice a grey or blue appearance on your fingernails, lips or inside of your mouth, stop using Depsone 100mg Tablet and consult a doctor immediately.
Depsone 100mg Tablet may reduce the sperm count or reduce the movement of the sperm, making it difficult to make your partner pregnant. However, if you have any concerns regarding this, please discuss them with your doctor.
Depsone 100mg Tablet is not effective against infections caused by viruses such as cold or flu. It is only used to kill bacteria or fungi. Therefore, you are recommended to consult a doctor if you have a cold or flu so that appropriate medication is prescribed.
No, you are not recommended to stop taking Depsone 100mg Tablet without consulting your doctor as it may worsen the condition. Therefore, take Depsone 100mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Depsone 100mg Tablet, please consult your doctor.

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