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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Depofem 10mg Tablet is used in the treatment of amenorrhea (absence of menstruation), irregular periods, uterine bleeding, endometrial hyperplasia (thickening of the uterus), and endometriosis. It works by replacing or supplementing the naturally produced female sex hormone called progesterone. This medicine may cause common side effects like headache, nausea, dizziness, hair loss, acne, unusual vaginal bleeding or spotting.

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Manufacturer/Marketer :

Cista Medicorp

Consume Type :

ORAL

Return Policy :

Not Returnable

About Depofem 10mg Tablet

Depofem 10mg Tablet is used to treat heavy, painful, irregular or missed periods, absence of periods, and uterine bleeding. It is also used to treat mild to moderate endometriosis and to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens. Depofem 10mg Tablet may also be used to prevent pregnancy.

Depofem 10mg Tablet contains medroxyprogesterone acetate that works by replacing or supplementing the naturally produced female sex hormone called progesterone. Depofem 10mg Tablet treats endometriosis by thinning the uterine lining, thereby preventing the spread of tissues from the uterus to other body parts. It helps prevent pregnancy by stopping the release of eggs from the ovaries (ovulation). 

Take Depofem 10mg Tablet as prescribed. In some cases, you may have headache, nausea, dizziness, hair loss, acne, unusual vaginal bleeding or spotting. Most of these side effects of Depofem 10mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Avoid taking Depofem 10mg Tablet if you are pregnant, think you may be pregnant, or if you are breastfeeding. Inform your doctor if you have/had breast cancer, unusual bleeding in the vagina, liver disease, or any other health problems. Avoid smoking and alcohol consumption to prevent any unpleasant side effects. Depofem 10mg Tablet may cause dizziness, so drive only if you are alert after taking Depofem 10mg Tablet.

Uses of Depofem 10mg Tablet

Treatment of Amenorrhea (absence of menstruation), irregular periods, uterine bleeding, endometrial hyperplasia (thickening of the uterus), endometriosis

Directions for Use

Swallow Depofem 10mg Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Depofem 10mg Tablet belongs to a group of medicines called progestogens used to treat heavy, painful, irregular or missed periods, absence of periods, and uterine bleeding. It is also used to treat mild to moderate endometriosis and to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens. Depofem 10mg Tablet may also be used to prevent pregnancy. Depofem 10mg Tablet contains medroxyprogesterone acetate that works by replacing or supplementing the naturally produced female sex hormone called progesterone. Depofem 10mg Tablet treats endometriosis by thinning the uterine lining, thereby preventing the spread of tissues from the uterus to other body parts. It helps prevent pregnancy by stopping the release of eggs from the ovaries (ovulation). 

How Depofem 10mg Tablet Works

Depofem 10mg Tablet contains medroxyprogesterone acetate that works by replacing or supplementing the naturally produced female sex hormone called progesterone. Depofem 10mg Tablet treats endometriosis by thinning the uterine lining, thereby preventing the spread of tissues from the uterus to other body parts. It helps prevent pregnancy by stopping the release of eggs from the ovaries (ovulation).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Depofem 10mg Tablet

  • Headache

  • Breast pain

  • Irregular vaginal bleeding or spotting

  • Stomach/abdominal cramps

  • Bloating

  • Nausea

  • Vomiting

  • Hair loss

What if I have taken an overdose of Depofem 10mg Tablet

Do not take more than the prescribed dose of Depofem 10mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not use Depofem 10mg Tablet if you are allergic to medroxyprogesterone acetate, or any other similar hormonal medicines, if you have/had breast cancer, venous/arterial thrombosis, liver problems, porphyria, if you are pregnant or think you may be pregnant. Tell your doctor before using Depofem 10mg Tablet if you have had a heart attack, stroke, blood clot, liver problems, kidney problems, asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, heart problems, thyroid, or have high calcium levels in your blood. Be cautious while driving as Depofem 10mg Tablet may cause dizziness.

Drug-Drug Interactions

verifiedApollotooltip
MedroxyprogesteroneEtretinate
Critical
MedroxyprogesteroneTranexamic acid
Critical

Drug-Drug Interactions

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MedroxyprogesteroneEtretinate
Critical
How does the drug interact with Depofem 10mg Tablet:
Taking Depofem 10mg Tablet and Etretinate may cause severe birth defects if the mother takes the medication during pregnancy.

How to manage the interaction:
Using etretinate and Depofem 10mg Tablet together is not recommended, but can be taken if prescribed by a doctor. However, if you experience unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneTranexamic acid
Critical
How does the drug interact with Depofem 10mg Tablet:
Taking Depofem 10mg Tablet acetate with Tranexamic acid may increase the risk of blood clots.

How to manage the interaction:
Taking Depofem 10mg Tablet with Tranexamic acid is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
MedroxyprogesteroneAcitretin
Critical
How does the drug interact with Depofem 10mg Tablet:
Coadministration of Acitretin with Depofem 10mg Tablet can increase the risk and severity of birth defects when taken by a pregnant woman.

How to manage the interaction:
Taking Acitretin with Depofem 10mg Tablet together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneBoceprevir
Severe
How does the drug interact with Depofem 10mg Tablet:
Taking boceprevir and Depofem 10mg Tablet may, decrease the blood levels and effects of Depofem 10mg Tablet.

How to manage the interaction:
Although taking Depofem 10mg Tablet and Boceprevir together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult your doctor immediately. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneFosamprenavir
Severe
How does the drug interact with Depofem 10mg Tablet:
Taking Depofem 10mg Tablet together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Although there is a possible interaction between Depofem 10mg Tablet and Fosamprenavir, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor right away. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneGriseofulvin
Severe
How does the drug interact with Depofem 10mg Tablet:
Taking griseofulvin with Depofem 10mg Tablet may reduce blood levels and the effects of Depofem 10mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Griseofulvin and Depofem 10mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, or if you think you might be pregnant while using birth control, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneSugammadex
Severe
How does the drug interact with Depofem 10mg Tablet:
When Depofem 10mg Tablet is taken with sugammadex, the effect of Depofem 10mg Tablet in the blood may decrease.

How to manage the interaction:
Taking Sugammadex with Depofem 10mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MedroxyprogesteroneAmprenavir
Severe
How does the drug interact with Depofem 10mg Tablet:
Taking Depofem 10mg Tablet with amprenavir may make amprenavir less effective.

How to manage the interaction:
There may be a possibility of interaction between Depofem 10mg Tablet and Amprenavir, but it can be taken if prescribed by a doctor. If you're having any unusual symptoms, it's important to contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
MedroxyprogesteroneDabrafenib
Severe
How does the drug interact with Depofem 10mg Tablet:
When Dabrafenib is taken with Depofem 10mg Tablet acetate, the amount of Depofem 10mg Tablet acetate in the blood may decrease.

How to manage the interaction:
Co-administration of Dabrafenib with Depofem 10mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience hot flashes(feeling of heat in the body), dryness, or unusual bleeding, don't hesitate to reach out to your doctor. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneBrigatinib
Severe
How does the drug interact with Depofem 10mg Tablet:
Taking Depofem 10mg Tablet and Brigatinib may, reduce the blood levels and effects of Depofem 10mg Tablet.

How to manage the interaction:
Although taking Depofem 10mg Tablet and brigatinib together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience hot flashes(feeling of heat in the body), dryness, or unusual bleeding, don't hesitate to reach out to your doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Besides this, weight-bearing exercises can help in making your bone strong. Aerobics, yoga, and activities like tai chi may help relax the body and mind.

  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours. 

  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.

  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 

  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Depofem 10mg Tablet Substitute

Substitutes safety advice
  • Deviry 10 mg Tablet 10's

    6.26per tablet
  • MEDROGEST TABLET 10'S

    by AYUR

    6.26per tablet
  • Orgamed 10 mg Tablet 10's

    4.95per tablet
  • Medveo 10 mg Tablet 10's

    5.49per tablet
  • Medache Tablet 10's

    9.86per tablet
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Alcohol

Caution

There is not enough scientific data available for Depofem 10mg Tablet interaction with alcohol. Hence it is best to consult a doctor.

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Pregnancy

Unsafe

Avoid taking Depofem 10mg Tablet if you are pregnant or think you may be pregnant as Depofem 10mg Tablet might affect the developing baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Depofem 10mg Tablet. Consult your doctor if you have any concerns.

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Driving

Caution

It is advised to drive with caution after taking Depofem 10mg Tablet as it may cause dizziness.

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Liver

Unsafe

Depofem 10mg Tablet is not recommended for people with liver problems. Consult a doctor if you have any concerns.

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Kidney

Caution

There is not enough scientific data available regarding the use of Depofem 10mg Tablet in people with kidney problems. Hence it is best to consult a doctor.

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Children

Unsafe

Depofem 10mg Tablet is not recommended for children below 12 years of age.

FAQs

Depofem 10mg Tablet is used to treat heavy, painful, irregular or missed periods, absence of periods, and uterine bleeding. It is also used to treat mild to moderate endometriosis and to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens. Depofem 10mg Tablet may also be used to prevent pregnancy.
Depofem 10mg Tablet contains medroxyprogesterone acetate that works by replacing or supplementing the naturally produced female sex hormone called progesterone.
Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy, and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high estrogen levels, and women can have decreased sex drive, weight gain, or gallbladder problems.
Yes, Depofem 10mg Tablet may cause weight gain. Eat healthy food and exercise regularly. If you feel that you are gaining a lot of weight while taking Depofem 10mg Tablet, please consult your doctor.
Do not use Depofem 10mg Tablet if you are allergic to medroxyprogesterone acetate, or any other similar hormonal medicines, if you have/had breast cancer, venous/arterial thrombosis, liver problems, porphyria, if you are pregnant or think you may be pregnant.
Continue taking Depofem 10mg Tablet for as long as it has been prescribed by the doctor. If you experience any difficulty while taking Depofem 10mg Tablet, consult a doctor.

Country of origin

India
Other Info - DE46276

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