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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:35 PM IST
Depin 5 Capsule is used to treat high blood pressure (hypertension). It is also used to reduce strokes and chest pain (angina) caused by the arteries' blockage. In addition to this, it is also used to treat preterm labour. It contains Nifedipine, which works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of stroke, heart attack, other heart problems, or kidney problems in the future. It may cause common side effects like low blood pressure, headache, slow heartbeat, dizziness, and rash in some cases. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

NIFEDIPINE-5MG

Manufacturer/Marketer

Cadila Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Depin 5 Capsule

Depin 5 Capsule belongs to a group of medications called Calcium channel blockers primarily used to treat high blood pressure (hypertension). Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease. It is also used to reduce strokes and chest pain (angina) caused by the arteries' blockage. In addition to this, Depin 5 Capsule is also used to treat preterm labour.

Depin 5 Capsule works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective and also for the best results.

Your doctor will advise you on how often you take Depin 5 Capsule based on your medical condition. You may experience common side effects like low blood pressure, headache, slow heartbeat, dizziness, and rash in some cases. Most of these side effects of Depin 5 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Let your doctor know if you have any liver or heart problems, are pregnant or breastfeeding. You should monitor your blood pressure regularly to be sure that the Depin 5 Capsule is working efficiently. And also, a healthy diet, and regular exercise is necessary to keep blood pressure under control. Do not eat grapefruit or drink grapefruit juice while you're taking nifedipine. It can make side effects worse. Even a small reduction in sodium in your diet helps improve your heart's health and reduce blood pressure.

Uses of Depin 5 Capsule

Treatment of Hypertension (high blood pressure).

Medicinal Benefits

Depin 5 Capsule works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, heart-related chest pain (angina) other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective and also for the best results.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Depin 5 Capsule

  • Low blood pressure

  • Headache

  • Slow heartbeat

  • Dizziness

  • Rash

Drug Warnings

Depin 5 Capsule should be taken with caution in patients with chest pain (angina), congestive heart failure, liver/kidney disease, hypotension (low blood pressure), peripheral oedema (swelling of hands/legs), and diabetes. You should monitor your blood pressure regularly to make sure the Depin 5 Capsule is working efficiently. Besides, this prolonged intake of Depin 5 Capsule can lower blood pressure (hypotension). So, daily monitoring of blood pressure is advisable. 

Drug Interactions

Drug-Drug Interaction: Depin 5 Capsule is known to interact when taken with an anticancer drug (quinidine), antiepileptic medicine (phenytoin), anti TB drug (rifampicin), antibiotics (erythromycin), other blood pressure-lowering pills and anti-psychotic drugs, anti-HIV drug (iamprendinavir, nelfinavir, ritonavir, saquinavir or amprenavir), drugs used to treat insomnia or anxiety (Phenobarbital).

Drug-Food Interaction: Please keep your doctor informed of what herbal products you are taking, especially St. John's wort (used in the treatment of depression).

Drug-Disease Interaction: Depin 5 Capsule is contraindicated in patients with severe aortic stenosis (narrowed heart valve), cardiogenic shock (when suddenly heart does not get enough blood supply), the recent history of unstable angina (chest pain), heart failure, and hypotension (low blood pressure).

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PHENYTOIN
  • RIFAMPICIN
  • ERYTHROMYCIN
  • NELFINAVIR
  • RITONAVIR
  • SAQUINAVIR
  • AMPRENAVIR
  • PHENOBARBITAL

Habit Forming

No

Diet & Lifestyle Advise

  • Weight loss is an effective lifestyle change for controlling blood pressure. Losing even a small amount of weight can be very helpful in lowering blood pressure.

  • Include a more healthy diet like whole grains, fruits, and low-fat dairy products in your food as it will effectively help lower blood pressure. Also, prefer eating home-cooked food and avoiding eating junk and outside food.

  • Do not eat grapefruit or drink grapefruit juice while you're taking nifedipine. It can make side effects worse.

  • Even a small reduction in sodium in your diet helps improve your heart's health and reduce blood pressure.

  • Regularly monitor your blood pressure as it can fluctuate and can lead to serious life-threatening effects.

  • Avoid the intake of alcoholic beverages with Depin 5 Capsule as it can make you dehydrated and affect your sleep. Drinking more amount of alcohol can actually raise blood pressure and affect the efficacy of Depin 5 Capsule .

Disease/Condition Glossary

High blood pressure: It is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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Alcohol

Caution

Alcohol consumption may increase the occurrence of unpleasant side effects.

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Pregnancy

Caution

If you are pregnant, think you may be pregnant, or plan to have a baby, ask your doctor for advice before taking this medicine. You may be able to use Depin 5 Capsule but only after special consideration by your doctor.

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Breast Feeding

Caution

Please do not take Depin 5 Capsule without a doctor's advice as it may pass through the breast milk.

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Driving

Caution

Depin 5 Capsule may cause side effects like dizziness, which could affect your ability to drive. Hence, drive or operate machinery only when you are alert.

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Liver

Caution

There is limited information available on the use of Depin 5 Capsule in patients with liver disease. Please consult your doctor.

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Kidney

Caution

Depin 5 Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment may not be needed in these patients. Please consult your doctor.

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Children

Caution

The safety and effectiveness of Depin 5 Capsule have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - DEP0011

Author Details

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FAQs

Depin 5 Capsule is used to treat high blood pressure (hypertension). It works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.
Yes, Depin 5 Capsule can cause a sudden drop in blood pressure especially when you start taking Depin 5 Capsule , to avoid sudden drop please get up gently when sitting down so as to avoid dizziness.
It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shot up at any time. If you have a persistent headache, please consult your doctor immediately.
If you miss a dose of Depin 5 Capsule , you are advised to take it as soon as you remember. However, if it's time for you to take your next dose, you should skip the missed one and continue your scheduled dose. Taking both the doses together can lead to very low blood pressure, hence avoid a double dose.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.
If you forget to take Depin 5 Capsule at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
Depin 5 Capsule , if stopped abruptly, may lead to withdrawal symptoms. Before stopping Depin 5 Capsule , consult your doctor; your dose will be lowered gradually to avoid any unpleasant side effects of Depin 5 Capsule .
Yes, in some cases, Depin 5 Capsule may cause headaches. Headaches should usually go away after the first week of taking nifedipine. Talk to your doctor if they last longer than a week or are severe.
Depin 5 Capsule belongs to a group of medications called Calcium channel blockers or calcium antagonists. However, research reports that nifedipine has an apparent diuretic and natriuretic effect on healthy volunteers.
Depin 5 Capsule is generally safe to take for a long time. In fact, it works best when taken for a long time. If you experience any adverse events, consult the doctor immediately.
In rare cases, Depin 5 Capsule can lead to Acute Kidney Injury (AKI) by causing deleterious kidney hemodynamic alterations.
A very rare but known adverse effect of Depin 5 Capsule is drug-induced liver injury. Seek medical attention if you experience any difficulty while using Depin 5 Capsule .
Nifedipine may impair insulin secretion at high glucose levels in patients with non-insulin-dependent mellitus. Seek medical attention if you experience any symptoms.
If you are pregnant, think you may be pregnant, or plan to have a baby, ask your doctor for advice before taking this medicine. You may be able to use Depin 5 Capsule , but only after special consideration by your doctor.
Nifedipine passes into breast milk in very small amounts and has not been known to cause side effects in breastfed babies. If you notice that your baby is not feeding as regularly, or if you have any other concerns, talk to your doctor.
In some cases, Depin 5 Capsule may cause palpitations. Usually, these do not require medical attention and gradually resolve over time. However, if these are persistent, contact your doctor.
Maintaining a healthy lifestyle is essential to benefit from Depin 5 Capsule . Eat a balanced diet, exercise regularly, manage stress, and limit alcohol and smoking. Following these tips can help control your blood pressure and improve your overall health.
Key lifestyle changes, such as quitting smoking, limiting alcohol intake, eating well, regular exercise, and minimizing stress, can boost heart health and reduce the occurrence of stroke and angina.
Depin 5 Capsule should not be discontinued without a doctor's consultation, as stopping Depin 5 Capsule may cause blood pressure to return to pre-treatment levels within a few days. Therefore, continue taking Depin 5 Capsule even if you feel well. Consult the doctor if you have any concerns.
If you miss a prescription dose, take it as soon as you recall and resume your regular routine. If you are near the next dose, skip the missing dose and resume your regular schedule. Do not take a double dose to make up for a forgotten dose.
It depends on your individual medical condition and response to the medication. Your doctor will determine the appropriate duration of treatment based on your specific needs.
Common side effects of Depin 5 Capsule may include low blood pressure, headache, slow heartbeat, dizziness, and rash in some cases. Most of these side effects of Depin 5 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

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