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  3. Depin 5 Capsule 50's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Depin 5 Capsule is used to treat high blood pressure (hypertension). It is also used to reduce strokes and chest pain (angina) caused by the arteries' blockage. In addition to this, it is also used to treat preterm labour. It contains Nifedipine, which works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of stroke, heart attack, other heart problems, or kidney problems in the future. It may cause common side effects like low blood pressure, headache, slow heartbeat, dizziness, and rash in some cases. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Depin 5 Capsule 50's, Pack of 50 CAPSULES
Depin 5 Capsule 50's, Pack of 50 CAPSULES
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Composition :

NIFEDIPINE-5MG

Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Depin 5 Capsule

Depin 5 Capsule belongs to a group of medications called Calcium channel blockers primarily used to treat high blood pressure (hypertension). Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease. It is also used to reduce strokes and chest pain (angina) caused by the arteries' blockage. In addition to this, Depin 5 Capsule is also used to treat preterm labour.

Depin 5 Capsule works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective and also for the best results.

Your doctor will advise you on how often you take Depin 5 Capsule based on your medical condition. You may experience common side effects like low blood pressure, headache, slow heartbeat, dizziness, and rash in some cases. Most of these side effects of Depin 5 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Let your doctor know if you have any liver or heart problems, are pregnant or breastfeeding. You should monitor your blood pressure regularly to be sure that the Depin 5 Capsule is working efficiently. And also, a healthy diet, and regular exercise is necessary to keep blood pressure under control. Do not eat grapefruit or drink grapefruit juice while you're taking nifedipine. It can make side effects worse. Even a small reduction in sodium in your diet helps improve your heart's health and reduce blood pressure.

Uses of Depin 5 Capsule

Treatment of Hypertension (high blood pressure).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Depin 5 Capsule works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, heart-related chest pain (angina) other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective and also for the best results.

How Depin 5 Capsule Works

Depin 5 Capsule works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective and also for the best results.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Depin 5 Capsule

  • Low blood pressure

  • Headache

  • Slow heartbeat

  • Dizziness

  • Rash

What if I have taken an overdose of Depin 5 Capsule

Do not take more than the prescribed dose of Depin 5 Capsule as it may cause overdose resulting in too low blood pressure causing dizziness especially on standing and fast or slow heartbeat. Other symptoms of overdose include increase in blood sugar level, increase in the acidity of blood, low blood oxygen levels, swelling in the lungs, and disturbances in consciousness, possibly leading to unconsciousness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Depin 5 Capsule should be taken with caution in patients with chest pain (angina), congestive heart failure, liver/kidney disease, hypotension (low blood pressure), peripheral oedema (swelling of hands/legs), and diabetes. You should monitor your blood pressure regularly to make sure the Depin 5 Capsule is working efficiently. Besides, this prolonged intake of Depin 5 Capsule can lower blood pressure (hypotension). So, daily monitoring of blood pressure is advisable. 

Drug-Drug Interactions

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NifedipineCarbamazepine
Critical
NifedipineFosphenytoin
Severe

Drug-Drug Interactions

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NifedipineCarbamazepine
Critical
How does the drug interact with Depin 5 Capsule 50's:
Coadministration of Depin 5 Capsule 50's with Carbamazepine can reduce the blood levels of Depin 5 Capsule 50's, which may make the medication less effective.

How to manage the interaction:
Taking Depin 5 Capsule 50's with Carbamazepine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NifedipineFosphenytoin
Severe
How does the drug interact with Depin 5 Capsule 50's:
When Fosphenytoin is taken with Depin 5 Capsule 50's, the amount of Fosphenytoin in the blood can be reduced.

How to manage the interaction:
Co-administration of Fosphenytoin with Depin 5 Capsule 50's can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like sweating, dizziness, confusion, drowsiness, sweating, chest pain or tightness, palpitations, headache, nausea, or vomiting, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
NifedipinePhenobarbital
Severe
How does the drug interact with Depin 5 Capsule 50's:
Phenobarbital can drastically lower Depin 5 Capsule 50's levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Depin 5 Capsule 50's can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
NifedipineRifabutin
Severe
How does the drug interact with Depin 5 Capsule 50's:
Coadministration of Depin 5 Capsule 50's with Rifabutin may significantly reduces the blood levels of Depin 5 Capsule 50's which may make the medication less effective.

How to manage the interaction:
Taking Depin 5 Capsule 50's with Rifabutin together is usually avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NifedipineRifampicin
Severe
How does the drug interact with Depin 5 Capsule 50's:
Coadministration of Depin 5 Capsule 50's with rifampicin can decrease the blood levels of Depin 5 Capsule 50's, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Depin 5 Capsule 50's and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
NifedipineModafinil
Severe
How does the drug interact with Depin 5 Capsule 50's:
Coadministration of Depin 5 Capsule 50's with Modafinil can reduce the levels of Depin 5 Capsule 50's in the body. This may lead to low treatment outcomes.

How to manage the interaction:
Taking Depin 5 Capsule 50's with Modafinil together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of increased heart rate, muscle cramps, tremors, cough, fever, nausea, vomiting, fatigue, edema, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
NifedipineTizanidine
Severe
How does the drug interact with Depin 5 Capsule 50's:
Coadministration of Depin 5 Capsule 50's with Tizanidine can increase the risk and severity of side effects like low blood pressure.

How to manage the interaction:
Taking Depin 5 Capsule 50's with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, you should contact a doctor immediately if you notice any symptoms of headaches, irritation, confusion, dizziness, oedema, fatigue, palpitations, sweating, irregular heartbeats, or constipation. Do not stop using any medications without talking to a doctor.
NifedipineEnzalutamide
Severe
How does the drug interact with Depin 5 Capsule 50's:
Taking Enzalutamide with Depin 5 Capsule 50's may decrease the blood levels of Depin 5 Capsule 50's, which may make Depin 5 Capsule 50's less effective in treating your condition.

How to manage the interaction:
Although taking Enzalutamide and Depin 5 Capsule 50's together can result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
NifedipineCeritinib
Severe
How does the drug interact with Depin 5 Capsule 50's:
Coadministration of ceritinib together with Depin 5 Capsule 50's can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Depin 5 Capsule 50's with ceritinib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
NifedipinePrimidone
Severe
How does the drug interact with Depin 5 Capsule 50's:
Coadministration of Depin 5 Capsule 50's with primidone may decrease the blood levels of Depin 5 Capsule 50's and reduce its effectiveness.

How to manage the interaction:
Taking Depin 5 Capsule 50's with Primidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NIFEDIPINE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NIFEDIPINE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice can significantly increase the blood levels and effects of Depin 5 Capsule 50's. Avoid or limit the consumption of grapefruit and grapefruit juice while being treated with Depin 5 Capsule 50's. Call a doctor if you experience side effects such as headache, low blood pressure, irregular heartbeat, swelling, and fluid retention.

Diet & Lifestyle Advise

  • Weight loss is an effective lifestyle change for controlling blood pressure. Losing even a small amount of weight can be very helpful in lowering blood pressure.

  • Include a more healthy diet like whole grains, fruits, and low-fat dairy products in your food as it will effectively help lower blood pressure. Also, prefer eating home-cooked food and avoiding eating junk and outside food.

  • Do not eat grapefruit or drink grapefruit juice while you're taking nifedipine. It can make side effects worse.

  • Even a small reduction in sodium in your diet helps improve your heart's health and reduce blood pressure.

  • Regularly monitor your blood pressure as it can fluctuate and can lead to serious life-threatening effects.

  • Avoid the intake of alcoholic beverages with Depin 5 Capsule as it can make you dehydrated and affect your sleep. Drinking more amount of alcohol can actually raise blood pressure and affect the efficacy of Depin 5 Capsule .

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Depin 5 Capsule Substitute

Substitutes safety advice

  • Nicardia 5 Capsule 10's

    ₹1.89per tablet

  • Depin 5 Softgel Capsule 30's

    ₹1.28per tablet

  • Calcigard-5 Capsule 10's

    ₹1.67per tablet

  • Nify 5 Tablet 10's

    ₹0.86per tablet

  • DEPICOR 5MG TABLET

    ₹4.23per tablet

Product Substitutes

Info icon

Nicardia 5 Capsule 10's

₹18.9

MRP ₹21

Info icon

Depin 5 Softgel Capsule 30's

₹38.3

MRP ₹42.5

Info icon

Calcigard-5 Capsule 10's

₹16.7

MRP ₹18.5

Info icon

Nify 5 Tablet 10's

₹8.6

MRP ₹9.5

Info icon

DEPICOR 5MG TABLET

₹42.28

MRP ₹46.98

Info icon

Nifelate 5mg Capsule

₹6.88

MRP ₹7.65

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Alcohol

Caution

Alcohol consumption may increase the occurrence of unpleasant side effects.

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Pregnancy

Caution

If you are pregnant, think you may be pregnant, or plan to have a baby, ask your doctor for advice before taking this medicine. You may be able to use Depin 5 Capsule but only after special consideration by your doctor.

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Breast Feeding

Caution

Please do not take Depin 5 Capsule without a doctor's advice as it may pass through the breast milk.

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Driving

Caution

Depin 5 Capsule may cause side effects like dizziness, which could affect your ability to drive. Hence, drive or operate machinery only when you are alert.

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Liver

Caution

There is limited information available on the use of Depin 5 Capsule in patients with liver disease. Please consult your doctor.

bannner image

Kidney

Caution

Depin 5 Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment may not be needed in these patients. Please consult your doctor.

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Children

Caution

The safety and effectiveness of Depin 5 Capsule have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

FAQs

Depin 5 Capsule is used to treat high blood pressure (hypertension). It works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.
Yes, Depin 5 Capsule can cause a sudden drop in blood pressure especially when you start taking Depin 5 Capsule , to avoid sudden drop please get up gently when sitting down so as to avoid dizziness.
It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shot up at any time. If you have a persistent headache, please consult your doctor immediately.
If you miss a dose of Depin 5 Capsule , you are advised to take it as soon as you remember. However, if it's time for you to take your next dose, you should skip the missed one and continue your scheduled dose. Taking both the doses together can lead to very low blood pressure, hence avoid a double dose.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.
If you forget to take Depin 5 Capsule at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
Depin 5 Capsule , if stopped abruptly, may lead to withdrawal symptoms. Before stopping Depin 5 Capsule , consult your doctor; your dose will be lowered gradually to avoid any unpleasant side effects of Depin 5 Capsule .
Yes, in some cases, Depin 5 Capsule may cause headaches. Headaches should usually go away after the first week of taking nifedipine. Talk to your doctor if they last longer than a week or are severe.
Depin 5 Capsule belongs to a group of medications called Calcium channel blockers or calcium antagonists. However, research reports that nifedipine has an apparent diuretic and natriuretic effect on healthy volunteers.
Depin 5 Capsule is generally safe to take for a long time. In fact, it works best when taken for a long time. If you experience any adverse events, consult the doctor immediately.
In rare cases, Depin 5 Capsule can lead to Acute Kidney Injury (AKI) by causing deleterious kidney hemodynamic alterations.
A very rare but known adverse effect of Depin 5 Capsule is drug-induced liver injury. Seek medical attention if you experience any difficulty while using Depin 5 Capsule .
Nifedipine may impair insulin secretion at high glucose levels in patients with non-insulin-dependent mellitus. Seek medical attention if you experience any symptoms.
If you are pregnant, think you may be pregnant, or plan to have a baby, ask your doctor for advice before taking this medicine. You may be able to use Depin 5 Capsule , but only after special consideration by your doctor.
Nifedipine passes into breast milk in very small amounts and has not been known to cause side effects in breastfed babies. If you notice that your baby is not feeding as regularly, or if you have any other concerns, talk to your doctor.
In some cases, Depin 5 Capsule may cause palpitations. Usually, these do not require medical attention and gradually resolve over time. However, if these are persistent, contact your doctor.
Maintaining a healthy lifestyle is essential to benefit from Depin 5 Capsule . Eat a balanced diet, exercise regularly, manage stress, and limit alcohol and smoking. Following these tips can help control your blood pressure and improve your overall health.
Key lifestyle changes, such as quitting smoking, limiting alcohol intake, eating well, regular exercise, and minimizing stress, can boost heart health and reduce the occurrence of stroke and angina.
Depin 5 Capsule should not be discontinued without a doctor's consultation, as stopping Depin 5 Capsule may cause blood pressure to return to pre-treatment levels within a few days. Therefore, continue taking Depin 5 Capsule even if you feel well. Consult the doctor if you have any concerns.
If you miss a prescription dose, take it as soon as you recall and resume your regular routine. If you are near the next dose, skip the missing dose and resume your regular schedule. Do not take a double dose to make up for a forgotten dose.
It depends on your individual medical condition and response to the medication. Your doctor will determine the appropriate duration of treatment based on your specific needs.
Common side effects of Depin 5 Capsule may include low blood pressure, headache, slow heartbeat, dizziness, and rash in some cases. Most of these side effects of Depin 5 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - DEP0011

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Author Details

Doctor imageDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:50 PM IST

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Reference

  1. https://www.nhs.uk/medicines/nifedipine/
  2. https://medlineplus.gov/druginfo/meds/a684028.html
  3. https://www.medicines.org.uk/emc/files/pil.655.pdf
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