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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:29 PM IST
Defoset-2.5 MD Tablet is an antipsychotic medicine used in the treatment of schizophrenia and bipolar disorder. This medication helps to improve mood, behavior, and thoughts by preventing the effects of dopamine and serotonin, two chemical messengers in the brain. Common side effects include drowsiness, dizziness, restlessness, tremors/shakiness, stomach upset, dry mouth, constipation, increased appetite, fatigue, and weight gain.
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Prescription drug

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Composition

OLANZAPINE-2.5MG

Manufacturer/Marketer

Better Meds

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-26

for this medicine

About Defoset-2.5 MD Tablet

Defoset-2.5 MD Tablet is used to treat schizophrenia and manic depression (bipolar disorder). Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. Manic depression, or bipolar disorder, is a serious brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioural changes.

Defoset-2.5 MD Tablet contains 'Olanzapine' that works by restoring the balance of chemical messengers (dopamine and serotonin) in the brain and improves thinking mood, and behaviour. It helps in clear thinking and decreases hallucinations. It is used for treating manic episodes of bipolar disorder and agitation in schizophrenia.

Take Defoset-2.5 MD Tablet as prescribed by your doctor. Common side effects include drowsiness, dizziness, restlessness, tremors/shakiness, stomach upset, dry mouth, constipation, increased appetite, fatigue, decreased libido, swelling of the hands or feet, and weight gain. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Defoset-2.5 MD Tablet is not recommended for treatment in patients with Dementia-Related Psychosis. Inform your doctor beforehand if you have a history of allergic reactions to Olanzapine, Alzheimer's disease, liver or kidney diseases, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, breast cancer, enlarged prostate, or fits before starting this medicine. If you are pregnant, planning to conceive, or a breastfeeding mother, inform your doctor before starting Defoset-2.5 MD Tablet . Avoid consuming alcohol while being treated with Defoset-2.5 MD Tablet as it can make you dizzy or drowsy. Do not drive or operate machinery while using Defoset-2.5 MD Tablet since it can make you sleepy. This medicine is not recommended for children below 12 years of age.

Uses of Defoset-2.5 MD Tablet

Treatment of Schizophrenia and Manic depression (bipolar disorder)

Medicinal Benefits

Defoset-2.5 MD Tablet is used to treat schizophrenia and manic depression (bipolar disorder). It effectively treats manic episodes of bipolar disorder and agitation in schizophrenia. It contains 'Olanzapine,' which belongs to the class of atypical antipsychotics. It works by restoring the balance of chemical messengers (dopamine and serotonin) in the brain. It is also known to improve thinking, mood, and behaviour. It helps in clear thinking and relieves psychotic symptoms like hallucinations.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew or break it. Melt-in-mouth tablets/Fast Dissolving tablets/Tablet MD: Do not touch these tablets with wet hands. These tablets dissolve rapidly when placed on the tongue. Take the tablet and place it on your tongue. Let it disperse/dissolve in your oral cavity, and swallow it. There is no need to take these tablets with water.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Defoset-2.5 MD Tablet

  • Drowsiness
  • Dizziness
  • Restlessness
  • Tremors/shakiness
  • Stomach upset
  • Dry mouth
  • Constipation
  • Increased appetite
  • Fatigue
  • Decreased libido
  • Swelling of the hands or feet
  • Weight gain

Drug Warnings

Defoset-2.5 MD Tablet is not recommended for treatment in patients with Dementia-Related Psychosis. Brief your medical history to the doctor if you have any allergic reactions, liver or kidney diseases, Alzheimer's disease, dementia, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, bowel problems, breathing problem during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits before starting Defoset-2.5 MD Tablet . Please consult your doctor if you are pregnant or planning to conceive before starting this medicine. Defoset-2.5 MD Tablet is not recommended during breastfeeding. Avoid consuming alcohol as it might lead to increased side effects like dizziness and drowsiness. Avoid driving or operating machinery as Defoset-2.5 MD Tablet may decrease your mental alertness, making you feel dizzy or drowsy. Defoset-2.5 MD Tablet is not recommended for people below 12 years of age as safety and effectiveness have not been established.

Drug Interactions

Drug-Drug Interaction: Defoset-2.5 MD Tablet may interact with opioid pain relievers (codeine, hydrocodone), anti-anxiety drugs (alprazolam, lorazepam, zolpidem), muscle relaxants (carisoprodol, cyclobenzaprine), anti-allergic drugs (cetirizine), common cold medicines (diphenhydramine), stomach emptying drugs (metoclopramide), antidepressants (escitalopram, fluoxetine, sertraline), and antipsychotics (quetiapine).

Drug-Food Interaction: Do not consume alcohol while taking Defoset-2.5 MD Tablet as it could lead to increased dizziness and drowsiness.

Drug-Disease Interaction: Before using Defoset-2.5 MD Tablet , let your doctor know if you have allergic reactions, liver or kidney diseases, Alzheimer's disease, dementia, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, bowel problems, sleep apnea, low white blood cell count, breast cancer, enlarged prostate, or fits. Defoset-2.5 MD Tablet is not recommended in Dementia-Related Psychosis.

Drug-Drug Interactions Checker List

  • CODEINE
  • HYDROCODONE
  • ALPRAZOLAM
  • LORAZEPAM
  • ZOLPIDEM
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • METOCLOPRAMIDE
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • QUETIAPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.

  • Exercise regularly as it helps in less cognitive decline and brain volume loss.

  • Avoid smoking and alcohol consumption.

  • Try to avoid stress by practising meditation or yoga.

  • Include fruits and vegetables in your diet as they contain antioxidants.

  • Eat nutritious food as it helps in cognitive stimulation.

  • Limit foods with high cholesterol and saturated fats.

  • Cut down on sugar, salt and processed foods.

  • Drink plenty of water.

  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

Special Advise

  • Let your doctor know that you are taking Defoset-2.5 MD Tablet if you are undergoing any medical tests.
  • Weight gain has been noticed in patients who use Olanzapine; hence, please take measures accordingly.
  • High blood pressure is also recorded in patients using this medicine; hence take appropriate measures accordingly by consulting your doctor.
  • Defoset-2.5 MD Tablet may affect blood glucose levels. Hence it is advised to monitor blood sugar levels regularly while using Defoset-2.5 MD Tablet . 
  • Timely monitoring of the cholesterol/triglyceride levels and Prolactin hormone levels is advised for the patient while using this medicine.

Disease/Condition Glossary

Schizophrenia: It is a condition in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganised thinking, loss of interest, lack of emotions, etc. Schizophrenia is triggered by physical, genetic, psychological, and environmental factors. Patients suffering from this disease may require lifelong treatment. Treatment involves a combination of medications, psychotherapy and care services.

Manic depression (bipolar disorder): A serious brain disorder in which a person goes through unusual mood changes (mood swings) and frequent changes in his/her behaviour and thinking.

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Alcohol

Unsafe

It is advised to avoid alcohol consumption while taking Defoset-2.5 MD Tablet . Alcohol intake and Defoset-2.5 MD Tablet may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Defoset-2.5 MD Tablet is a pregnancy category C drug. Using antipsychotic drugs during the third trimester of pregnancy can cause muscle problems in newborn babies. Please inform your doctor before taking Defoset-2.5 MD Tablet if you are pregnant or planning to conceive. Your doctor will weigh the potential risks and benefits before prescribing Defoset-2.5 MD Tablet .

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Breast Feeding

Unsafe

Defoset-2.5 MD Tablet is excreted into the breast milk; hence it is not recommended for a nursing mother. Inform your doctor before taking Defoset-2.5 MD Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Defoset-2.5 MD Tablet may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please inform your doctor if you have a liver impairment or any concerns.

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Kidney

Caution

Please inform your doctor before using Defoset-2.5 MD Tablet if you suffer from severe kidney impairment. Your doctor may adjust the dose if necessary based on your condition.

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Children

Unsafe

Defoset-2.5 MD Tablet is not recommended in people below 12 years of age.

Country of origin

India
Other Info - DEF0423

FAQs

Defoset-2.5 MD Tablet is used to treat schizophrenia and manic depression (bipolar disorder).
Defoset-2.5 MD Tablet is used to treat schizophrenia and manic depression (bipolar disorder).
Defoset-2.5 MD Tablet contains Olanzapine which works by balancing the chemical messengers like dopamine and serotonin located in the brain, improving mood, behaviour and thoughts.
Defoset-2.5 MD Tablet should be used with caution in the medical history of allergic reactions, liver or kidney diseases, heart problems, breathing problems, Alzheimer's disease, high cholesterol, glaucoma, diabetes, stomach/intestinal problems, breathing problem during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits. Please let your doctor know if you have any other medical problems before starting Defoset-2.5 MD Tablet .
Defoset-2.5 MD Tablet may make you sweat less and can likely cause heart stroke. Hence, limiting activities that cause overheating, like an exercise in hot weather or using hot tubs, is advised. Drink plenty of fluids and dress lightly.
Defoset-2.5 MD Tablet may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.
Olanzapine can cause side effects like orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Defoset-2.5 MD Tablet are advised to regularly monitor their blood pressure levels to avoid such unpleasant events. It is also advised to be aware of a condition called tardive dyskinesia (uncontrolled movements of the face, lips, mouth, tongue, arms or legs) that may rarely occur while using this medicine.
No, Defoset-2.5 MD Tablet is not a sleeping aid. It's an antipsychotic medication used to treat bipolar disorder and schizophrenia, not insomnia. If you need help with sleep, consult your healthcare provider or pharmacist for appropriate guidance and treatment.
Defoset-2.5 MD Tablet is an antipsychotic medication that takes time to start working. It may take several weeks (typically 4-6 weeks or longer) to notice significant symptom improvements. Be patient and consistent with your medication regimen, and schedule regular follow-ups with your healthcare provider to monitor progress and adjust the treatment plan as needed. They will help you determine the effectiveness of the medication and make any necessary adjustments.
Do not stop taking Defoset-2.5 MD Tablet suddenly; otherwise, your symptoms may return. If you need to stop taking olanzapine, your doctor will help you come off it by gradually reducing your dose. This will help prevent withdrawal symptoms.
There are no adequate and well-controlled studies on pregnant women. Please inform your doctor before taking Defoset-2.5 MD Tablet if you are pregnant or planning pregnancy. Your doctor will weigh the potential risks and benefits before prescribing Defoset-2.5 MD Tablet .
Defoset-2.5 MD Tablet is not indicated for treating children and adolescents below 18. Please seek medical advice.
Defoset-2.5 MD Tablet may cause dizziness or drowsiness. To ensure your safety, avoid driving or operating machinery if you're not mentally alert or experiencing symptoms that affect your concentration.
Yes, many people take Defoset-2.5 MD Tablet for a long time, including for several months or years, without any problems. However, it's important to remember that you should only take Defoset-2.5 MD Tablet as your healthcare provider prescribes. Regular monitoring and follow-up appointments with your healthcare provider are crucial to ensure the medication's safety and effectiveness. Your healthcare provider may also adjust your dosage or switch you to a different medication if needed.
When you start taking olanzapine, you may feel more relaxed and calmer. Within 2-3 weeks, you may notice improvements in your symptoms. Olanzapine can help you focus and think more clearly, stay on top of tasks, remember things more easily, connect with others, and distinguish between reality and delusions. It may also reduce or stop hearing voices.
Avoid drinking alcohol while taking olanzapine, especially during the initial treatment phase. Alcohol can exacerbate the medication's side effects, making you feel drowsy and unsteady. Excessive or daily alcohol consumption can worsen your symptoms and reduce the effectiveness of olanzapine. To ensure your safety and the medication's efficacy, it's best to abstain from alcohol or consult your healthcare provider for guidance.
Defoset-2.5 MD Tablet is not typically used to treat anxiety, although some research has explored its potential in this area. It has not been approved for anxiety treatment, and your doctor will usually prescribe other medications as a first-line treatment for anxiety; however, if you're experiencing anxiety in conjunction with another condition that olanzapine is approved to treat, such as bipolar disorder or schizophrenia. In that case, your doctor may consider it part of your overall treatment plan.'
The common side effects of the Defoset-2.5 MD Tablet are nausea, vomiting, diarrhea, constipation, sores in the mouth and throat, pain, burning, or tingling in the hands or feet, pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected, hair loss, pain, weakness, loss in ability to taste food. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

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