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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Deflu-Plus Tablet is a combination medicine primarily used to treat the common cold. This medicine works by inhibiting the action of histamine, a chemical messenger responsible for causing allergies. It helps relieve congestion, sneezing, nasal and sinus congestion, and nasal swelling, common cold, flu, allergies and other breathing problems like sinusitis and bronchitis. Common side effects include drowsiness, headache, dizziness, tiredness, disturbance in attention, and dry mouth.
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Whats That

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Synonym :

CAFFEINE+DIPHENHYDRAMINE HYDROCHLORIDE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE

Consume Type :

ORAL

Return Policy :

Not Returnable

About Deflu-Plus Tablet

Deflu-Plus Tablet is used to treat symptoms of the common cold, such as sneezing, runny nose, fever, headache, body pains, congestion, stuffy nose, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as “rhinoviruses”. The virus enters the body through the nose, mouth, or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs, or talks.

Deflu-Plus Tablet is a combination of four drugs: Caffeine, Diphenhydramine, Paracetamol and Phenylephrine. Caffeine is a stimulant that increases the effect of paracetamol. Diphenhydramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreasing mucus production. Together, Deflu-Plus Tablet helps to provide relief from common cold symptoms.

Take Deflu-Plus Tablet as prescribed by your doctor. You are advised to take Deflu-Plus Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience drowsiness, headache, dizziness, tiredness, disturbance in attention, and dry mouth. Most of these side effects of Deflu-Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Deflu-Plus Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, you are advised to consult a doctor before taking Deflu-Plus Tablet. Deflu-Plus Tablet is not recommended for children below 12 years. Please do not take more than the prescribed dose of Deflu-Plus Tablet as it may cause severe liver damage. Avoid excessive intake of caffeine as it may cause shaking, difficulty sleeping, and uncomfortable feelings in the chest.

Uses of Deflu-Plus Tablet

Treatment of Common cold symptoms

Directions for Use

Take Deflu-Plus Tablet with or without food as prescribed by your doctor. Swallow it whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Deflu-Plus Tablet contains Caffeine, Diphenhydramine, Paracetamol and Phenylephrine. Caffeine is a stimulant that increases the effect of paracetamol and decreases drowsiness caused by Diphenhydramine. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Diphenhydramine is an anti-allergic drug that blocks the action of histamine, a substance responsible for causing allergic reactions.  Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreasing mucus production. Together, Deflu-Plus Tablet helps to provide relief from symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

How Deflu-Plus Tablet Works

Deflu-Plus Tablet is a combination of four drugs: Caffeine, Diphenhydramine, Paracetamol and Phenylephrine. Caffeine is a stimulant that increases the effect of paracetamol. Diphenhydramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreasing mucus production. Together, Deflu-Plus Tablet helps to provide relief from common cold symptoms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Deflu-Plus Tablet

  • Drowsiness

  • Headache

  • Dizziness

  • Tiredness

  • Disturbance in attention

  • Dry mouth

What if I have taken an overdose of Deflu-Plus Tablet

Do not take more than the prescribed dose of Deflu-Plus Tablet as it may cause severe liver damage. Avoid excessive intake of caffeine as it may cause shaking, difficulty sleeping and uncomfortable feeling in the chest.

Drug Warnings

If you are allergic to Deflu-Plus Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, you are advised to consult a doctor before taking Deflu-Plus Tablet. Deflu-Plus Tablet is not recommended for children below 12 years. Do not take more than the prescribed dose of Deflu-Plus Tablet as it may cause severe liver damage. Avoid excessive intake of caffeine as it may cause shaking, difficulty sleeping and uncomfortable feeling in the chest. If you experience anxiety, nervousness, diarrhoea, high blood pressure or dizziness while taking Deflu-Plus Tablet, please consult a doctor.

Drug-Drug Interactions

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CaffeinePhenelzine
Critical
CaffeineLinezolid
Critical

Drug-Drug Interactions

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CaffeinePhenelzine
Critical
How does the drug interact with Deflu-Plus Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Deflu-Plus Tablet with Phenelzine is not recommended, please consult your doctor before taking it. They can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
CaffeineLinezolid
Critical
How does the drug interact with Deflu-Plus Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Deflu-Plus Tablet with Linezolid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineIsocarboxazid
Critical
How does the drug interact with Deflu-Plus Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Deflu-Plus Tablet with Isocarboxazid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineTranylcypromine
Critical
How does the drug interact with Deflu-Plus Tablet:
Coadministration of tranylcypromine with Deflu-Plus Tablet can in cause severe high blood pressure.

How to manage the interaction:
Taking Deflu-Plus Tablet with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Do not discontinue any medications without consulting a doctor.
DiphenhydramineSodium oxybate
Critical
How does the drug interact with Deflu-Plus Tablet:
Taking Deflu-Plus Tablet with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Deflu-Plus Tablet with Sodium oxybate is not recommended, but it can be taken if prescribed by a doctor. However contact your doctor if you experience shortness of breath, increased sweating, palpitations, or confusion. Do not stop using any medications without consulting a doctor.
DiphenhydramineThioridazine
Critical
How does the drug interact with Deflu-Plus Tablet:
When Thioridazine is taken with Deflu-Plus Tablet, it can slow down the way Deflu-Plus Tablet is broken down in the body.

How to manage the interaction:
Taking Deflu-Plus Tablet with Thioridazine is not recommended, please consult your doctor before taking it. It can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
DiphenhydraminePotassium chloride
Critical
How does the drug interact with Deflu-Plus Tablet:
Taking Deflu-Plus Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Deflu-Plus Tablet with Potassium chloride is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, contact your doctor. Do not stop taking any medication without consulting your doctor.
DiphenhydraminePotassium citrate
Critical
How does the drug interact with Deflu-Plus Tablet:
Taking Deflu-Plus Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Deflu-Plus Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DiphenhydramineEliglustat
Critical
How does the drug interact with Deflu-Plus Tablet:
When Deflu-Plus Tablet is taken with Eliglustat, it can cause a decrease in metabolism.

How to manage the interaction:
Taking Deflu-Plus Tablet with Eliglustat is not recommended, please consult your doctor before taking it. It can be taken if prescribed by your doctor. Do not stop taking any medication without consulting your doctor.
PhenylephrinePropofol
Critical
How does the drug interact with Deflu-Plus Tablet:
Taking Deflu-Plus Tablet with Propofol may lead to increased levels of Deflu-Plus Tablet leading to side effects like high blood pressure.

How to manage the interaction:
Taking Deflu-Plus Tablet with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.

  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.

  • Drink plenty of fluids to avoid dehydration. 

  • Gargle with salt water for relief from sore throat. 

  • Avoid consumption of alcohol with Deflu-Plus Tablet as it may cause tiredness, drowsiness or lack of concentration.

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS

Deflu-Plus Tablet Substitute

Substitutes safety advice
  • Corinite Tablet 10's

    4.64per tablet
  • KV Cold Tablet 10's

    5.40per tablet
  • Flieflu Tablet 10's

    by AYUR

    4.50per tablet
  • Nazoark Tablet 10'S

    by AYUR

    3.33per tablet
  • Lynocold Capsule 10's

    4.50per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Deflu-Plus Tablet as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with Deflu-Plus Tablet.

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Pregnancy

Unsafe

Deflu-Plus Tablet is not recommended for pregnant women. However, please consult a doctor if you are pregnant.

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Breast Feeding

Caution

Please consult a doctor before taking Deflu-Plus Tablet if you are a breastfeeding mother.

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Driving

Caution

Deflu-Plus Tablet may cause blurred vision, dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Deflu-Plus Tablet.

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Liver

Caution

Take Deflu-Plus Tablet with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Deflu-Plus Tablet with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Deflu-Plus Tablet is not recommended for children below 12 years of age. However, please consult a doctor before giving Deflu-Plus Tablet to children.

FAQs

Deflu-Plus Tablet is used to treat symptoms of the common cold, such as sneezing, runny nose, fever, headache, body pains, congestion, stuffy nose, or watery eyes.
Deflu-Plus Tablet contains Caffeine, Diphenhydramine, Paracetamol and Phenylephrine. Caffeine increases the effect of paracetamol and decreases drowsiness caused by Diphenhydramine. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Diphenhydramine blocks the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreasing mucus production. Together, Deflu-Plus Tablet helps to provide relief from symptoms of the common cold.
Yes, Deflu-Plus Tablet may cause drowsiness. It is not necessary for everyone taking Deflu-Plus Tablet to experience this side effect. Therefore, avoid driving if you feel drowsy after taking Deflu-Plus Tablet.
Deflu-Plus Tablet may be used to relieve pain and fever. Deflu-Plus Tablet contains Paracetamol, an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
You are not recommended to take Deflu-Plus Tablet with medicines containing Paracetamol. However, please consult a doctor before taking Deflu-Plus Tablet with other medicines.
No, you are not recommended to stop taking Deflu-Plus Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Deflu-Plus Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Deflu-Plus Tablet, please consult your doctor.
While taking Deflu-Plus Tablet you should avoid foods rich in carbohydrates and pectin like jellies, cabbage, and broccoli, as well as chocolate, caffeine-containing foods. Also, avoid consumption of alcohol with Deflu-Plus Tablet as it may increase the risk of liver damage and causes increased drowsiness, dizziness, and difficulty in concentrating. However take the advice of your doctor if you have any concerns.
Deflu-Plus Tablet may rarely cause serious side effects which includes allergic reactions, skin rash or peeling, mouth ulcers, breathing problems, unexplained bleeding, recurrent fevers or infections, vision disturbances and fast or irregular heartbeat. If you experience any of these symptoms, please consult your doctor immediately.
No, it is not advisable to breastfeed while using Deflu-Plus Tablet, as it contains diphenhydramine, which can enter breast milk and can be harmful to the unborn child. Therefore, consult your doctor before starting Deflu-Plus Tablet if you are breastfeeding.
No, taking a higher than the recommended dose of Deflu-Plus Tablet will not make it more effective and can actually increase the risk of serious side effects and toxicity. If you feel that your current dose is not effective, consult your doctor.
If you allergic to Deflu-Plus Tablet, avoid taking it. If you have high blood pressure, myasthenia gravis (muscle weakness), seizures (fits), glaucoma, hyperthyroidism (overactive thyroid), chronic obstructive pulmonary disease (COPD), enlarged prostate gland, kidney, liver, heart and urinary problems, inform your doctor before taking Deflu-Plus Tablet.
Store Deflu-Plus Tablet at room temperature in a cool and dry place away from sunlight. Keep it out of reach of children.
The common side effects of Deflu-Plus Tablet are drowsiness, headache, dizziness, tiredness, disturbance in attention, and dry mouth. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - DE66904

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