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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Defispas Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. It contains Dicyclomine and Mefenamic acid which relieve contractions associated with the smooth muscles of the abdomen and reduce mild to moderate pain and inflammation. It may cause common side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Synonym :

DICYCLOMINE HYDROCHLORIDE+MEFENAMIC ACID

Manufacturer/Marketer :

Megma Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Defispas Tablet

Defispas Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Abdominal (tummy) pain occurs between the chest and pelvic region (below the belly button and leg). Menstrual cramps, also known as dysmenorrhea, are characterised by cramps and pain during menstruation. A colic is a form of pain that starts and stops abruptly.

Defispas Tablet is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, Defispas Tablet helps in relieving pain.

You are advised to take Defispas Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Defispas Tablet may cause common side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Defispas Tablet may cause dizziness and drowsiness, so drive with caution. Defispas Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Defispas Tablet as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Defispas Tablet

Treatment of Abdominal pain, dysmenorrhea (period pain), and colicky pain.

Directions for Use

Take Defispas Tablet with food to prevent stomach upset. Swallow Defispas Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Defispas Tablet is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Defispas Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, Defispas Tablet helps in relieving pain.

How Defispas Tablet Works

Defispas Tablet is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, Defispas Tablet helps in relieving pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Defispas Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Headache
  • Dry mouth
  • Weakness
  • Nervousness
  • Loss of appetite

What if I have taken an overdose of Defispas Tablet

Do not take more than the prescribed dose of Defispas Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Defispas Tablet if you are allergic to any of its contents, if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. Inform your doctor if you have/had asthma, glaucoma, myasthenia gravis, high blood pressure, inflammatory bowel disease, paralytic ileus, intestinal atony, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Defispas Tablet may cause dizziness and drowsiness, so drive only if you are alert. Defispas Tablet should not be given to children as safety has not been established. Avoid consuming alcohol with Defispas Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Defispas Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Defispas Tablet unless prescribed. 

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
Mefenamic acidKetorolac
Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
How does the drug interact with Defispas Tablet 12's:
Co-administration of Defispas Tablet 12's with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Defispas Tablet 12's with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Defispas Tablet 12's:
Coadministration of Defispas Tablet 12's with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Defispas Tablet 12's with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
DicyclominePramlintide
Critical
How does the drug interact with Defispas Tablet 12's:
Co-administration of Pramlintide with Defispas Tablet 12's can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Defispas Tablet 12's with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium chloride
Critical
How does the drug interact with Defispas Tablet 12's:
Co-administration of Defispas Tablet 12's with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Defispas Tablet 12's with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium citrate
Critical
How does the drug interact with Defispas Tablet 12's:
Taking Defispas Tablet 12's and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Defispas Tablet 12's with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Mefenamic acidNaproxen
Severe
How does the drug interact with Defispas Tablet 12's:
Coadministration of Defispas Tablet 12's with Naproxen can increase the risk or severity of stomach bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Defispas Tablet 12's with Naproxen together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidBaricitinib
Severe
How does the drug interact with Defispas Tablet 12's:
Using Defispas Tablet 12's and baricitinib together may increase the risk of gastrointestinal perforation (a serious health condition where a hole develops through the stomach or intestine).

How to manage the interaction:
Co-administration of Defispas Tablet 12's with Baricitinib can result in an interaction, but it can be taken if your doctor has advised it. If you notice any signs like severe stomach pain, fever, or vomiting, consult a doctor. Do not stop using any medications without talking to a doctor.
Mefenamic acidFondaparinux
Severe
How does the drug interact with Defispas Tablet 12's:
Taking Defispas Tablet 12's with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Fondaparinux with Defispas Tablet 12's can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding or bruising, feeling dizzy or lightheaded, dark or bloody stools, headache, weakness contact your doctor right away. Do not stop using any medications without first talking to your doctor.
Mefenamic acidDasatinib
Severe
How does the drug interact with Defispas Tablet 12's:
Co-administration of Defispas Tablet 12's with Dasatinib can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Defispas Tablet 12's with Dasatinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, red or black tarry stools, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidPiroxicam
Severe
How does the drug interact with Defispas Tablet 12's:
Coadministration of Defispas Tablet 12's with Piroxicam can increase the risk side effects such as inflammation(swelling with redness and pain), bleeding, ulceration, and perforation leading to serious blood loss.

How to manage the interaction:
Taking Defispas Tablet 12's with Piroxicam together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.

  • Massages can also be helpful.

  • Avoid freezing and hot temperatures.

  • Avoid wearing tight-fitting clothes, instead, wear loose garments.

  • Rest well, and get plenty of sleep.

  • To avoid developing pressure sores, change your position every two hours.

  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.

  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANTISPASMODICS

Defispas Tablet Substitute

Substitutes safety advice
  • Spandril Tablet 10's

    12.15per tablet
  • Cyclomeff Tablet 10's

    5.72per tablet
  • PARASPAS TABLET

    3.56per tablet
  • Spastech Tablet 10's

    5.39per tablet
  • Cijo-Spas Tablet

    4.23per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Defispas Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended to breastfeed while taking Defispas Tablet . Consult your doctor before taking Defispas Tablet if you are breastfeeding.

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Driving

Caution

Defispas Tablet may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Unsafe

Defispas Tablet should not be used in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Defispas Tablet is not recommended for children as safety and effectiveness were not established.

FAQs

Defispas Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain.
Defispas Tablet contains Dicyclomine and Mefenamic acid. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.
Diarrhoea might be a side-effect of Defispas Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.
Defispas Tablet is used to treat colicky pain. Colic is a pain that is usually intestinal or urinary in nature that comes and goes and intensifies and eases gradually.
Dry mouth could be a side-effect of Defispas Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.
Defispas Tablet should not be taken for more than 7days. Do not take Defispas Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding.
Defispas Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Defispas Tablet only as prescribed, and do not overdose.
No, Defispas Tablet may not cause infertility. Consult the doctor if you have any concerns.
Yes, it is safe to use Defispas Tablet during periods if prescribed by the doctor. It helps relieve period cramps.
Defispas Tablet may prolong prothrombin time (blood test to measure blood clotting time). Therefore, frequent monitoring of prothrombin time is advised while taking this medication.
Defispas Tablet starts working within an hour.
Do not take Defispas Tablet on an empty stomach. Take Defispas Tablet with meals or immediately after meals to prevent stomach upset.
No, Defispas Tablet is recommended for headaches and toothache. It is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain.
Yes, Defispas Tablet can be taken with food or immediately after food.
No, Defispas Tablet does not stop menstruation. It does not affect the menstrual bleeding or the duration of periods. It only helps relieve menstrual cramps.
Defispas Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Defispas Tablet may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.
Yes, Defispas Tablet is a painkiller. It contains Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Defispas Tablet helps relieve abdominal pain, colicky pain, and period pains.
Yes, Defispas Tablet is safe if taken in the dose and duration prescribed by the doctor.
Defispas Tablet is not recommended for children as safety and effectiveness were not established.
Defispas Tablet should be used during pregnancy only if prescribed by the doctor. Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.
Defispas Tablet may cause side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Talk to your doctor if these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

No. 1065, Street No. 1, Haripur, Sector - 4,, Panchkula, 160022.
Other Info - DEF0327

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