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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Decapeptyl 3.75mg Injection is used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. It contains Triptorelin which works by inhibiting the synthesis of testosterone in men and oestrogen in women. In some cases, this medicine may cause side effects such as hot flashes, dizziness, headache, flu symptoms, nausea, vomiting, diarrhoea, upset stomach and swelling in the legs. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Ferring Pharmaceuticals Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Decapeptyl 3.75mg Injection

Decapeptyl 3.75mg Injection belongs to the class of 'anti-neoplastic agents', primarily used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland's cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon.

Decapeptyl 3.75mg Injection contains Triptorelin that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. Triptorelin is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. The lowering of testosterone hormone levels in men helps slows down the growth of cancer cells in prostate cancer.

Use Decapeptyl 3.75mg Injection as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Decapeptyl 3.75mg Injection include hot flashes, decreased sexual interest, shrinking of the testicles, breast tenderness or swelling, dizziness, headache, flu symptoms, nausea, vomiting, diarrhoea, upset stomach and swelling in legs. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not take or stop this medicine, if the doctor did not advise you to do so. Before starting Decapeptyl 3.75mg Injection, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Decapeptyl 3.75mg Injection is not indicated for use in pregnant and breastfeeding women. Decapeptyl 3.75mg Injection may make you feel dizzy, hence drive when you are alert only. Decapeptyl 3.75mg Injection is not recommended for children below two years of age.

Uses of Decapeptyl 3.75mg Injection

Treatment of Prostate cancer, endometriosis and precocious puberty.

Medicinal Benefits

Decapeptyl 3.75mg Injection contains Triptorelin, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Decapeptyl 3.75mg Injection is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Being an anti-neoplastic or anticancer agent, Decapeptyl 3.75mg Injection works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. Decapeptyl 3.75mg Injection reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helps in shrinking of endometriosis. Decapeptyl 3.75mg Injection also has the role of a contraceptive drug.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Decapeptyl 3.75mg Injection

  • Hot flashes
  • Decreased sexual interest
  • Shrinking of the testicles
  • Breast tenderness or swelling
  • Dizziness
  • Headache
  • Flu 
  • Nausea
  • Vomiting
  • Diarrhoea
  • Upset stomach
  • Swelling in legs 

Drug Warnings

Inform your doctor if you have any allergic reactions to Decapeptyl 3.75mg Injection or other medications. Before starting Decapeptyl 3.75mg Injection, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Decapeptyl 3.75mg Injection may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking Decapeptyl 3.75mg Injection. Decapeptyl 3.75mg Injection can affect the unborn baby when used in pregnancy. Hence, Decapeptyl 3.75mg Injection is not indicated for use in pregnancy and breastfeeding women. If you are using Decapeptyl 3.75mg Injection, make sure to use reliable forms of contraception to prevent pregnancy during the course. Decapeptyl 3.75mg Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Decapeptyl 3.75mg Injection can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Decapeptyl 3.75mg Injection is not recommended for children younger than two years of age.

Drug Interactions

Drug-Drug Interaction: Decapeptyl 3.75mg Injection may interact with heart rhythm problems treating drugs (quinidine, procainamide, amiodarone, sotalol), antibiotics (moxifloxacin), opioid pain killers (methadone) and antipsychotics.

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: Decapeptyl 3.75mg Injection should be used with caution in cases of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • MOXIFLOXACIN
  • METHADONE

Habit Forming

No

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. 
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
  • Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.

Special Advise

  • Your doctor may advise liver function tests to monitor your liver health since Decapeptyl 3.75mg Injection may cause increased liver enzymes (alanine aminotransferase, serum aspartate and serum transaminases).
  • Decapeptyl 3.75mg Injection may cause increased serum glucose levels (hyperglycaemia), hence inform your doctor if you have diabetes before starting Decapeptyl 3.75mg Injection.
  • Your doctor may advise blood tests and regular examinations of the prostate.
  • It is advised to get an electrocardiogram (ECG) done timely to monitor your heart health.

Disease/Condition Glossary

Prostate cancer: It is the cancer of the prostate gland (a small gland under the bladder that secretes fluid that nourishes and protects sperm) found only in men. The symptoms include difficulty in urination, pain, numbness or sexual problems. It is the most common type of cancer in men.

Endometriosis: It is a disorder in which tissue lining the uterus grows outside the uterine cavity. It commonly involves ovaries, fallopian tubes and the tissue lining the pelvis. Symptoms of endometriosis include pain and irregular periods.

Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon. If puberty begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Symptoms in a girl include first period and breast development, whereas, in boy, it causes enlarged testicles and penis,  deepening voice and facial hair.

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Alcohol

Caution

It is advised to avoid alcohol consumption to minimize the unwanted effects of Decapeptyl 3.75mg Injection. Please consult your doctor for more information.

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Pregnancy

Unsafe

Decapeptyl 3.75mg Injection is a pregnancy category X drug. It is unsafe to use Decapeptyl 3.75mg Injection in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using Decapeptyl 3.75mg Injection.

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Breast Feeding

Unsafe

Decapeptyl 3.75mg Injection is unsafe to use during breastfeeding. Consult your doctor for further information.

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Driving

Unsafe

Decapeptyl 3.75mg Injection causes dizziness and affects your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Decapeptyl 3.75mg Injection.

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Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment before starting Decapeptyl 3.75mg Injection.

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Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting Decapeptyl 3.75mg Injection.

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Children

Caution

Decapeptyl 3.75mg Injection is not recommended in children younger than two years of age.

Country of origin

India

Manufacturer/Marketer address

K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Other Info - DEC0024

Author Details

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FAQs

Decapeptyl 3.75mg Injection is used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children.
Decapeptyl 3.75mg Injection contains Triptorelin, a synthetic hormone. It helps reduce the testosterone and oestrogen hormones in men and women, respectively. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis in women.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
Decapeptyl 3.75mg Injection should be used with caution and under doctor's supervision only if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Let your doctor know if you have any other medical concerns before using Decapeptyl 3.75mg Injection.
During treatment with Decapeptyl 3.75mg Injection in the first few weeks, a temporary increase in hormones may occur before they decrease. This may cause new or worsening of side effects of Decapeptyl 3.75mg Injection. This is a normal response of your body to Decapeptyl 3.75mg Injection. However, if you notice any symptoms that are not manageable, please seek medical advice.
Decapeptyl 3.75mg Injection may worsen your mood disorders like depression. Hence it is advised to use Decapeptyl 3.75mg Injection only when you are free from any kind of mental problems. Please consult your doctor for more information.
Decapeptyl 3.75mg Injection may cause impotence and affect fertility in men. It is advised to speak to your doctor if you plan to have a family in the future before starting Decapeptyl 3.75mg Injection.

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