Debrilyse Plus Tablet is used to treat pain and inflammation associated with osteoarthritis (joint pain, especially in the knees, hip, hands, neck, and lower back) and rheumatoid arthritis (joint pain, especially in the hands and feet). It may also provide relief from toothache, ear pain, throat pain, muscle ache, and backache.

Debrilyse Plus Tablet contains Trypsin, Bromelain, Rutoside, and Diclofenac. Trypsin and Bromelain reduce pain and inflammation by increasing the blood supply to the affected area and promoting healing. Rutoside prevents swelling and inflammation by neutralizing the chemicals that cause cell damage. Diclofenac blocks the release of chemical substances that cause pain and inflammation.

Take Debrilyse Plus Tablet exactly as prescribed by your doctor. Debrilyse Plus Tablet may cause side effects such as nausea, vomiting, stomach pain, indigestion, heartburn, stomach upset, diarrhoea, and headache. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult a doctor immediately.

Consult your doctor if you are pregnant or breastfeeding. Debrilyse Plus Tablet is not recommended for children below 12 years of age. Debrilyse Plus Tablet may cause dizziness, so do not drive or operate heavy machinery unless you are alert. Keep your doctor informed about your health conditions and medications to rule out any interactions/side effects.

Debrilyse Plus Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside, and Diclofenac. Trypsin and Bromelain are enzymes with antiseptic and anti-inflammatory properties. They reduce pain and inflammation by increasing the blood supply to the affected area and promoting healing. Rutoside is an antioxidant and anti-inflammatory agent. It prevents further swelling and inflammation by neutralizing the chemicals (free radicals) that cause cell damage. Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) that prevents the production of chemical substances (prostaglandins) that cause pain and inflammation.

• Nausea
• Vomiting
• Stomach pain
• Indigestion
• Heartburn
• Stomach upset
• Diarrhoea
• Headache

Do not take Debrilyse Plus Tablet if you are allergic to any of its contents. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, angina, bowel problems, blood clotting disorder, a habit of smoking, or liver and kidney problems. Consult your doctor if you are pregnant or breastfeeding. Stop taking Debrilyse Plus Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.

Drug-Drug Interactions: Inform the doctor if you are taking painkillers (aspirin), anticoagulants (warfarin), anti-depressants (duloxetine, lithium), or antibiotics (chloramphenicol).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have/had a stomach ulcer or perforation, bleeding problems, bypass surgery, heart attack, blood circulation problems, inflammation of the intestines, anaemia, heart, kidney or liver problems.

• ASPIRIN
• WARFARIN
• DULOXETINE
• LITHIUM
• CHLORAMPHENICOL

• Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on the treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.

• Try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize levels of chemicals called cytokines, which ramp up inflammation.

• Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. It can be temporary (acute) or lifelong (chronic) in nature. Acute pain lasts for a short time and is caused by damage to the tissues of the muscle, bone, or organs. In contrast, chronic pain lasts for a longer duration and can occur due to severe inflammation or tissue damage, such as in cases of osteoarthritis and rheumatoid arthritis.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.