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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dasamyl 50 mg Tablet is used to treat Philadelphia chromosome-positive chronic myeloid leukaemia and acute lymphoblastic leukaemia. It contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce their further spread to other parts of the body.

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Composition :

DASATINIB-50MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Dasamyl 50 mg Tablet

Dasamyl 50 mg Tablet is an anti-cancer medicine used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. There are different types of blood cancers. Dasamyl 50 mg Tablet is used in the treatment of chronic myelogenous leukemia (CML) in patients with chronic, accelerated, or blast phase Ph+ (Philadelphia chromosome-positive) who are resistant or intolerant to prior therapy, in patients with newly diagnosed chronic Ph+ chronic myelogenous leukemia (CML). This medicine is also used in the treatment of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).

Dasamyl 50 mg Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

Dasamyl 50 mg Tablet may cause certain side effects, such as skin rash, fatigue, headache, musculoskeletal pain, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, GI bleeding, muscle inflammation, myalgia, and difficulty breathing. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dasamyl 50 mg Tablet should be taken as advised by your doctor. Do not take more than the recommended dose of medicine. Your doctor will decide the dose of Dasamyl 50 mg Tablet based on the severity of your condition.

Dasamyl 50 mg Tablet should be avoided if you are allergic to it or any other components present in it. Before taking Dasamyl 50 mg Tablet , caution should be exercised if you have/had liver/kidney disease, gastrointestinal disorders, cardiac problems, and myelosuppression as may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment with Dasamyl 50 mg Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment.

Uses of Dasamyl 50 mg Tablet

Treatment of Philadelphia chromosome-positive chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia

Directions for Use

Take Dasamyl 50 mg Tablet as advised by your doctor. Do not take more than the prescribed dose of medicine. Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine.

Medicinal Benefits

Dasamyl 50 mg Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins (BCR-ABL tyrosine kinase) that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. Dasamyl 50 mg Tablet is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia.

How Dasamyl 50 mg Tablet Works

Dasamyl 50 mg Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dasamyl 50 mg Tablet

  • Nausea
  • Diarrhoea
  • Decreased platelet count
  • Fatigue
  • Edema
  • Vomiting
  • Diarrhea
  • Headache
  • Back pain
  • Dizziness
  • Skin rash
  • Difficulty breathing
  • GI bleeding
  • Myalgia

What if I have taken an overdose of Dasamyl 50 mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Dasamyl 50 mg Tablet are unusual bruising or bleeding, fever, sore throat, chills, and/or other signs of infection, shortness of breath, fast heartbeat, headache, pale skin, confusion and tiredness. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Dasamyl 50 mg Tablet should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before taking, inform your doctor if you have liver/kidney disease, diabetes, cardiac problems, increased blood pressure, or gastrointestinal disorders, as the use of Dasamyl 50 mg Tablet in these patients may cause serious side effects. Dasamyl 50 mg Tablet may cause myelosuppression, fluid retention, gastrointestinal haemorrhage, QT prolongation, congestive heart failure, Left ventricular dysfunction and Myocardial infarction. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Breastfeeding should be discontinued in nursing mothers during the treatment. Dasamyl 50 mg Tablet is given in children above one year of age only if prescribed by the doctor. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Drug-Drug Interactions

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DasatinibDronedarone
Critical
DasatinibPimozide
Critical

Drug-Drug Interactions

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DasatinibDronedarone
Critical
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Using dronedarone together with Dasamyl 50 mg Tablet 60's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasamyl 50 mg Tablet 60's with Dronedarone is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.
DasatinibPimozide
Critical
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Using Pimozide together with Dasamyl 50 mg Tablet 60's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasamyl 50 mg Tablet 60's with Pimozide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibHalofantrine
Critical
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Using Halofantrine together with Dasamyl 50 mg Tablet 60's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasamyl 50 mg Tablet 60's with Halofantrine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without doctor's advice.
DasatinibMesoridazine
Critical
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Using Mesoridazine together with Dasamyl 50 mg Tablet 60's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Dasamyl 50 mg Tablet 60's is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibCimetidine
Severe
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Using Dasamyl 50 mg Tablet 60's together with Cimetidine may decrease the blood levels of Dasamyl 50 mg Tablet 60's.

How to manage the interaction:
Although taking Dasamyl 50 mg Tablet 60's and Cimetidine together can cause an interaction, it can be taken if a doctor has suggested it. Consult a doctor in case of any unusual side effects. Do not discontinue any medications without consulting a doctor.
DasatinibHaloperidol
Severe
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Co-administration of Dasamyl 50 mg Tablet 60's with Haloperidol can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dasamyl 50 mg Tablet 60's with Haloperidol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms like dizziness, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DasatinibClopidogrel
Severe
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Taking Clopidogrel and Dasamyl 50 mg Tablet 60's together can increase the risk of bleeding.

How to manage the interaction:
Taking Clopidogrel together with Dasamyl 50 mg Tablet 60's may result in an interaction, but they can be taken if prescribed by a doctor. However, if you experience dizzy or lightheaded, red or black, sticky stools, or a severe headache, consult a doctor without any delay. Do not discontinue any medication without consulting a doctor.
DasatinibPantoprazole
Severe
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Taking Dasamyl 50 mg Tablet 60's with Pantoprazole may decrease the blood levels of Dasamyl 50 mg Tablet 60's and reduce its effectiveness.

How to manage the interaction:
Taking Pantoprazole with Dasamyl 50 mg Tablet 60's together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
DasatinibPhenobarbital
Severe
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Taking Dasamyl 50 mg Tablet 60's with Phenobarbital may significantly reduce the blood levels of Dasamyl 50 mg Tablet 60's.

How to manage the interaction:
Taking Phenobarbital with Dasamyl 50 mg Tablet 60's together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
DasatinibDolasetron
Severe
How does the drug interact with Dasamyl 50 mg Tablet 60's:
Using Dolasetron together with Dasamyl 50 mg Tablet 60's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dolasetron with Dasamyl 50 mg Tablet 60's together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, breathlessness, or heart palpitations. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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DASATINIB-50MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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DASATINIB-50MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice can significantly increase the blood levels and effects of Dasamyl 50 mg Tablet 60's. Avoid consumption of Grapefruit juice with Dasamyl 50 mg Tablet 60's. However, contact a doctor if you experience dizziness, shortness of breath, heart palpitations, pain, or burning during urination.

Diet & Lifestyle Advise

  • After beginning your treatment, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Dasamyl 50 mg Tablet Substitute

Substitutes safety advice
  • Invista 50 Tablet 10's

    65.79per tablet
  • Spnib 50 mg Tablet 60's

    46.48per tablet
  • Rytstat 50 mg Tablet 6's

    99.00per tablet
  • Dasanat 50 mg Tablet 60's

    88.83per tablet
  • Daslemia 50 mg Tablet 60's

    3070.90per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Dasamyl 50 mg Tablet to prevent serious adverse effects.

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Pregnancy

Unsafe

When given to a pregnant woman, Dasamyl 50 mg Tablet may cause fetal harm. There have been no sufficient and well-controlled investigations of Dasamyl 50 mg Tablet in pregnant women. Women of reproductive potential should avoid becoming pregnant while undergoing treatment with this medicine.

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Breast Feeding

Unsafe

It is not known if Dasamyl 50 mg Tablet passes into your breast milk. Inform your doctor if you are breastfeeding. You should not breastfeed while taking this medicine and for 2 weeks of the treatment with Dasamyl 50 mg Tablet . Your doctor may prescribe an alternative based on the symptoms and health condition.

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Driving

Unsafe

Dasamyl 50 mg Tablet may cause dizziness and may make you feel drowsy. Hence, avoid driving or operating machines after taking Dasamyl 50 mg Tablet or until you become alert.

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Liver

Caution

Use Dasamyl 50 mg Tablet with caution if you have liver disease. Your doctor may monitor your liver function while taking this medicine. No dose adjustments are necessary in patients with liver impairment.

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Kidney

Caution

There are presently no clinical investigations with Dasamyl 50 mg Tablet in patients with compromised renal function. If you have kidney problems, inform your doctor before taking this medicine.

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Children

Consult your doctor

Dasamyl 50 mg Tablet is safe for use in children above one year of age if prescribed by the doctor.

FAQs

Dasamyl 50 mg Tablet is used to treat Philadelphia chromosome-positive chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.
Dasamyl 50 mg Tablet contains Dasatinib, which works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells.
Dasamyl 50 mg Tablet is known to cause embryo-fetal toxicity; hence, it is contraindicated for use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least six months after completion of the treatment.
Take antacids such as aluminium hydroxide/magnesium hydroxide, calcium carbonate, calcium carbonate, and magnesium 2 hours before or after taking Dasamyl 50 mg Tablet as antacids may alter the absorption of this medicine.

Country of origin

India

Manufacturer/Marketer address

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7Th To 12Th Floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103.
Other Info - DAS0087

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