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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

Dapute 350mg Injection is used to treat bacterial infections. It contains Daptomycin, which belongs to the cyclic lipopeptide class of antibiotics, which works by inhibiting the process of bacterial cell wall synthesis that is required for its survival. Thus, it kills bacteria and prevents the growth of bacterial infection. Common side effects of Dapute 350mg Injection may include injection site reactions, rash, vomiting, allergic reaction, chest pain, hypotension, increased sweating, difficulty sleeping, dizziness, sore throat, nausea, and diarrhoea.

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Composition

DAPTOMYCIN-350MG

Manufacturer/Marketer

Concord Laboratories Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Dapute 350mg Injection

Dapute 350mg Injection is an antibiotic used to treat bacterial infections. It is used to treat complicated skin and skin structure infections and blood infections such as bacteremia (presence of bacteria in the bloodstream) and right-sided infective endocarditis (inflammation/swelling of the inner lining of the heart due to the presence of bacteria). A bacterial infection occurs when harmful bacteria enter the body, multiply and cause infection. It can infect any part of the body and multiply very quickly. Dapute 350mg Injection is only effective in treating infections caused by bacteria and not effective for viral infections like flu or a common cold.

Dapute 350mg Injection contains Daptomycin, which belongs to the cyclic lipopeptide class of antibiotics. It works against various types of bacteria. This medicine works by inhibiting the process of bacterial cell wall synthesis that is required for its survival. Thus, Dapute 350mg Injection kills bacteria and prevents the growth of bacterial infection. 

Dapute 350mg Injection may cause certain common side effects such as injection site reactions, rash, vomiting, allergic reaction, chest pain, hypotension, increased sweating, difficulty sleeping, dizziness, sore throat, nausea, and diarrhoea. Most of these side effects are mild and subside over time. However, if these persist, contact your doctor immediately. This medicine is a parenteral formulation. A qualified healthcare doctor will administer it. Hence, do not self-administer.

Dapute 350mg Injection should be avoided if you are allergic to it or other antibiotics. Dapute 350mg Injection should be used with caution if you have liver problems, kidney disease, myasthenia gravis, myopathy, rhabdomyolysis, eosinophilic pneumonia, peripheral neuropathy, heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level). Inform your doctor if you have/had diarrhoea for more than four days. However, do not take any anti-diarrheal medicine until your doctor tells you. Birth control pills may not work effectively while using this medication. So, speak to your doctor about using non-hormonal birth control to avoid pregnancy. If you are pregnant or breastfeeding, inform your doctor before receiving Dapute 350mg Injection. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

Uses of Dapute 350mg Injection

Dapute 350mg Injection is used in the treatment of Bacterial infections

Medicinal Benefits

Dapute 350mg Injection is a broad-spectrum antibiotic that is effective against a wide range of bacterial infections. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. Dapute 350mg Injection contains Daptomycin, which belongs to the cyclic lipopeptide class of antibiotics. It works against various types of bacteria. This medicine works by inhibiting the process of bacterial cell wall synthesis that is required for its survival. Thus, Dapute 350mg Injection kills bacteria and prevents the growth of bacterial infection.

Directions for Use

A qualified healthcare professional will administer a dose of Dapute 350mg Injection. Do not self-administer.Dapute 350mg Injection, when given intravenously (IV), can be administered in children above six years of age. When this medicine is given via subcutaneous (SC) route, it can be administered in children above two years of age.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dapute 350mg Injection

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Dizziness
  • Difficulty breathing
  • Hypotension
  • Chest pain
  • Sore throat
  • Increased sweating
  • Injection site reactions

Drug Warnings

Avoid receiving Dapute 350mg Injection if you are allergic to it or other antibiotics. Dapute 350mg Injection should be used with caution if you have liver problems, kidney disease, myasthenia gravis, myopathy, rhabdomyolysis, eosinophilic pneumonia, peripheral neuropathy, heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level). Inform your doctor if you have/had diarrhoea for more than four days. However, do not take any anti-diarrheal medicine until your doctor tells you. Dapute 350mg Injection is ineffective for treating pneumonia and left-sided infective endocarditis. Birth control pills may not work effectively while using this medication. So, speak to your doctor about using non-hormonal birth control to avoid pregnancy. If you are pregnant or breastfeeding, inform your doctor before receiving Dapute 350mg Injection. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy is not established.

Drug Interactions

Drug-Drug Interactions: Dapute 350mg Injection should not be given with Typhoid vaccine (live), anti-gout medicine (allopurinol/ probenecid), birth control pills.

Drug-Food Interactions: Avoid consumption of alcohol while receiving Dapute 350mg Injection as it can cause serious side effects. 

Drug-Disease Interactions: Dapute 350mg Injection should not be administered in patients with Renal dysfunction, liver disease, myopathy, peripheral neuropathy, rhabdomyolysis, and hemodialysis.

Drug-Drug Interactions Checker List

  • TYPHOID VACCINE
  • ALLOPURINOL
  • PROBENECID
  • CHOLERA VACCINE

Habit Forming

No

Diet & Lifestyle Advise

  • Diarrhea may happen as a side effect. Taking probiotics after receiving Dapute 350mg Injection may help. Talk to your doctor if you notice blood stools or develop stomach cramps.
  • Drink plenty of fluids to avoid an upset stomach and hydrate your body.
  • Avoid intake of alcoholic beverages with Dapute 350mg Injection as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Dapute 350mg Injection in fighting off infections.
  • Maintain good hygiene and avoid contaminated or processed food.
  • Include more fibre-enriched food like whole-grain bread and brown rice in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. 
  • Avoid taking too much calcium-enriched foods and drinks as it might affect the working of Dapute 350mg Injection.

Special Advise

  • Even if you feel better after receiving Dapute 350mg Injection, do not stop the administration of it. This might cause the symptoms to reappear and will make the infection difficult to treat due to antibiotic resistance.
  • Make sure you drink plenty of fluids when you are sick. This will, in general, help you clear out the infection faster, protect you from dehydration, and help you overcome some unpleasant side effects of taking Dapute 350mg Injection.
  • Stop receiving Dapute 350mg Injection and consult your doctor immediately if you develop any allergic reactions such as itching, skin rash, swelling of the face, throat, tongue, and breathing difficulties.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any part of the body and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections. Dapute 350mg Injection does not work against infections caused by viruses, including colds and flu. Dapute 350mg Injection is used to treat skin and skin structure infections, bacteremia and right-sided infective endocarditis.

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Alcohol

Unsafe

Avoid consumption of alcohol while receiving treatment with Dapute 350mg Injection as it may worsen your condition.

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Pregnancy

Caution

Limited data are available for the use of Dapute 350mg Injection in pregnancy. Hence, this medicine should not be used in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or planning a pregnancy before receiving Dapute 350mg Injection.

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Breast Feeding

Caution

Limited data are available for the use of Dapute 350mg Injection in breastfeeding. Hence, this medicine should not be used in breastfeeding mothers unless clearly necessary. So, inform your doctor if you are breastfeeding your child before receiving Dapute 350mg Injection.

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Driving

Unsafe

Avoid driving vehicles or operating machines as Dapute 350mg Injection causes dizziness and makes you feel sleepy or dizzy.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Dapute 350mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Dapute 350mg Injection should be used under caution in patients with kidney disease. Inform your doctor if you have kidney problems. Your doctor will prescribe only if the benefits outweigh the risks. If prescribed, your doctor may adjust the dose based on your health condition.

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Children

Unsafe

Dapute 350mg Injection is not recommended for use in children below 12 years of age as the safety and efficacy is not established

Country of origin

INDIA

Manufacturer/Marketer address

Survey No: 249, Brahmanapally(V), Hayathnagar(M),R.R.District, Hyderabad, Telangana, INDIA – 501511
Other Info - DAP0020

FAQs

Dapute 350mg Injection is used to treat Bacterial infections.
Dapute 350mg Injection contains daptomycin, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria.
Do not use anti-diarrhoeal medication until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhea as it may help in increasing the number of good bacteria in the intestine, which aids in digestion.
No, Dapute 350mg Injection is not used to treat lung infections such as pneumonia caused by bacteria.
Dapute 350mg Injection does not work against viral infection. So, it should not be taken to treat the common cold or cough. Consult your doctor if you have these symptoms.
As Dapute 350mg Injection is injectable, it can start working soon after administration. However, Dapute 350mg Injection may take a few days to kill the bacteria and prevent further spread of infection.
Dapute 350mg Injection belongs to the cyclic lipopeptide class of antibiotics. It targets various types of bacteria by treating bacterial infections, including complicated skin and skin structure infections, blood infections such as bacteraemia (bacteria in the bloodstream), and right-sided infective endocarditis (inflammation of the inner lining of the heart caused by bacteria). The medication works by inhibiting bacterial cell wall synthesis, a process essential for bacterial survival. This action effectively kills bacteria and prevents the spread of the infection.
Dapute 350mg Injection should be administered by the doctor or nurse through an intravenous route (into the vein) over 2 minutes. Do not self-administer.
Dapute 350mg Injection is generally considered safe when used as prescribed by a doctor and do not skip the schedule of receiving Dapute 350mg Injection. However, it may cause side effects in some individuals, so consult the doctor for personalized advice.
The side effects of Dapute 350mg Injection include rash, injection site reactions, vomiting, allergic reaction, chest pain, hypotension, increased sweating, difficulty sleeping, dizziness, sore throat, nausea, and diarrhoea. Most of these side effects are mild and typically go away on their own over time. However, if any symptoms persist or worsen, consult the doctor immediately.
If you experience dizziness while taking Dapute 350mg Injection, lie down for a while and then get up slowly. Moving cautiously can also help manage dizziness. Avoid coffee, cigarettes, and alcohol. Consult the doctor, if the dizziness persists or worsens.

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