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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Danogen-50 Capsule is used to treat endometriosis and breast cysts. It contains Danazol which works by decreasing the amount of oestrogen in the body and shrinks the tissue or stops its growth. In some cases, this medicine may cause side effects such as sore throat, hoarse voice, hair loss, excessive hair growth on the body or face, and stomach pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Composition :

DANAZOL-50MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Danogen-50 Capsule

Danogen-50 Capsule belongs to the class of drugs called synthetic steroids used to treat endometriosis and breast cysts. Endometriosis is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain.

Danogen-50 Capsule contains Danazol which works by suppressing the activity of ovaries. Thus, it decreases the amount of estrogen in the body and induces temporary menopause. Thereby, it shrinks the tissue outside the uterus or stops its growth.

Take Danogen-50 Capsule as prescribed by your doctor. You are advised to take Danogen-50 Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience sore throat, hoarse voice, hair loss, excessive hair growth on the body or face, stomach pain, skin rashes, or chest pain. Most of these side effects of Danogen-50 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Danogen-50 Capsule or any other medicines, please tell your doctor. Danogen-50 Capsule is contraindicated in pregnant and breastfeeding women. You are recommended to avoid or limit consumption of alcohol with Danogen-50 Capsule as it may cause shortness of breath or make you feel sick. Drive only if you are alert as Danogen-50 Capsule may cause dizziness, vertigo (spinning feeling), or blurred vision. If you are about to undergo any surgery, please inform your doctor that you are taking Danogen-50 Capsule as it may increase the effect of certain anesthetics.

Uses of Danogen-50 Capsule

Treatment of Endometriosis, Breast lumps

Directions for Use

Take Danogen-50 Capsule with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Danogen-50 Capsule contains Danazol which decreases the amount of estrogen in the body by suppressing the activity of ovaries. Thus, Danogen-50 Capsule induces temporary menopause and shrinks the tissue outside the uterus or stops its growth. Also, Danogen-50 Capsule works by inhibiting the release of hormones in the body that cause breast pain and lumps.

How Danogen-50 Capsule Works

Danogen-50 Capsule contains Danazol which works by suppressing the activity of ovaries. Thus, it decreases the amount of estrogen in the body and induces temporary menopause. Thereby, it shrinks the tissue outside the uterus or stops its growth.

Storage

Store in a cool and dry place away from sunlight
Side effects of Danogen-50 Capsule
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • To keep your vocal cords lubricated and hydrated, drink lots of water.
  • Suck on ice chips, popsicles, or lozenges to clear your throat and reduce hoarseness.
  • Your voice cords may be soothed and healed by honey's antibacterial and anti-inflammatory properties.
  • Gargle with salt water.
  • Using a steam humidifier or inhaling steam might help minimize hoarseness and release mucus.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

What if I have taken an overdose of Danogen-50 Capsule

Take Danogen-50 Capsule only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dark urine, severe stomach/abdominal pain, and yellowing eyes/skin. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Danogen-50 Capsule or any other medicines, please tell your doctor. Danogen-50 Capsule is contraindicated in pregnant and breastfeeding women. It is advised to use effective non-hormonal contraceptives to avoid pregnancy while taking Danogen-50 Capsule as it may cause birth defects. You are recommended to avoid or limit consumption of alcohol with Danogen-50 Capsule as it may cause shortness of breath or make you feel sick. Drive only if you are alert as Danogen-50 Capsule may cause dizziness, vertigo (spinning feeling), or blurred vision. If you are about to undergo any surgery, please inform your doctor that you are taking Danogen-50 Capsule as it may increase the effect of certain anesthetics. If you have pain while moving your legs or arms, stop taking Danogen-50 Capsule and consult a doctor immediately as this might be due to a blood clot.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Danogen-50 Capsule:
Using pimozide together with Danogen-50 Capsule may significantly increase the blood levels of pimozide.

How to manage the interaction:
Taking Danogen-50 Capsule with Pimozide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.
How does the drug interact with Danogen-50 Capsule:
Combining Danogen-50 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin.

How to manage the interaction:
Taking Danogen-50 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DanazolCerivastatin
Severe
How does the drug interact with Danogen-50 Capsule:
Using cerivastatin together with Danogen-50 Capsule may significantly increase the blood levels of cerivastatin.

How to manage the interaction:
Although there is a possible interaction between Danogen-50 Capsule and Cerivastatin, you can take these medicines together if prescribed by your doctor. However, if you experience a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DanazolHalofantrine
Severe
How does the drug interact with Danogen-50 Capsule:
Using Halofantrine together with Danogen-50 Capsule may increase the blood levels of Halofantrine.

How to manage the interaction:
Although there is a possible interaction between Danogen-50 Capsule and Halofantrine, you can take these medicines together if prescribed by your doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, contact a doctor right away. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Danogen-50 Capsule:
Coadministration of Ketoconazole and Danogen-50 Capsule may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Danogen-50 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, yellowing of the skin or eyes, consult the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Danogen-50 Capsule:
Coadministration of Warfarin with Danogen-50 Capsule can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Danogen-50 Capsule and warfarin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Danogen-50 Capsule:
Using Lovastatin together with Danogen-50 Capsule may significantly increase the blood levels of Lovastatin.

How to manage the interaction:
Although there is a possible interaction between Danogen-50 Capsule and Lovastatin, you can take these medicines together if prescribed by your doctor. However, if you experience a muscle tenderness, muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes contact a doctor right away. Do not discontinue any medications without first consulting your doctor.
DanazolLomitapide
Severe
How does the drug interact with Danogen-50 Capsule:
Combining Lomitapide with Danogen-50 Capsule can increase the blood levels of Lomitapide.

How to manage the interaction:
Co-administration of Danogen-50 Capsule with Lomitapide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience diarrhea, nausea, stomach pain, constipation, or any other discomfort, fever, joint pain, or skin rash consult a doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Danogen-50 Capsule:
Co-administration of Vilazodone with Danogen-50 Capsule can increase the blood levels of Vilazodone.

How to manage the interaction:
Taking Danogen-50 Capsule with Vilazodone together can result in an interaction, but it can be taken if a doctor has advised it. If you experience any symptoms such as diarrhea, nausea, vomiting, dry mouth, dizziness, or sleep disturbances, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Danogen-50 Capsule:
Combining Leflunomide with Danogen-50 Capsule may increase the risk of liver problems.

How to manage the interaction:
Although taking Danogen-50 Capsule and Leflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, liver damage, or bleeding - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, and do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

SYNTHETIC ANABOLIC STEROID
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Alcohol

Unsafe

Avoid or limit alcohol consumption with Danogen-50 Capsule as it may cause shortness of breath or make you feel sick.

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Pregnancy

Unsafe

Danogen-50 Capsule is not recommended for pregnant women as it may cause birth defects. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Danogen-50 Capsule is contraindicated in breastfeeding women as small amounts of Danogen-50 Capsule may be excreted in breast milk. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Danogen-50 Capsule may cause dizziness, vertigo (spinning feeling) or blurred vision. Therefore, avoid driving if you experience any of these symptoms after taking Danogen-50 Capsule .

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Liver

Caution

Take Danogen-50 Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Danogen-50 Capsule if you have severe liver disease.

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Kidney

Caution

Take Danogen-50 Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Danogen-50 Capsule if you have severe kidney disease.

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Children

Caution

Please consult a doctor regarding the use of Danogen-50 Capsule in children.

Have a query?

FAQs

Danogen-50 Capsule contains Danazol that works by suppressing the activity of ovaries. Thus, it decreases the amount of oestrogen in the body and induces temporary menopause. Thereby, it shrinks the tissue outside the uterus or stops its growth.

You are not recommended to use a contraceptive pill with Danogen-50 Capsule as it may decrease the effectiveness of hormonal contraceptives. Therefore, it is advised to use effective non-hormonal contraceptives such as Intra-Uterine Device or barrier method in conjunction with contraceptive jelly or foam. However, please consult a doctor if you have any concerns regarding this.

Danogen-50 Capsule may be used to treat breast lumps when other treatments have not worked. Danogen-50 Capsule inhibits the release of hormones in the body that cause breast pain and lumps.

Danogen-50 Capsule may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Danogen-50 Capsule and inform your doctor if you have diabetes before taking Danogen-50 Capsule .

You are not recommended to take Danogen-50 Capsule with simvastatin as it may increase the levels of simvastatin in the blood and increase the risk of liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue). However, please consult a doctor before taking Danogen-50 Capsule with other medicines.

Danogen-50 Capsule is not recommended for patients suffering from severe liver disease as it may worsen the condition. Therefore, inform your doctor if you have any liver disease before taking Danogen-50 Capsule .

Danogen-50 Capsule is used to treat endometriosis (tissue lining the uterus grows outside the uterus) and breast cysts.

Danogen-50 Capsule may cause side effects such as hoarse voice, sore throat, stomach pain, hair loss, skin rashes, chest pain and excessive hair growth on face or body. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - DAN0003

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