apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:50 PM IST
Dablexa 75 Capsule is used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It contains Dabigatran, which works by inhibiting the production of clotting factors and prevents blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. It may cause side effects such as bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Composition

DABIGATRAN-75MG

Manufacturer/Marketer

Abbott India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Dablexa 75 Capsule

Dablexa 75 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.

Dablexa 75 Capsule contains ‘Dabigatran’, which works by inhibiting the production of clotting factors Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Dablexa 75 Capsule helps prevent blood clots if you have an increased risk of having a heart attack, or stroke.

Take Dablexa 75 Capsule as prescribed by your doctor. You are advised to take Dablexa 75 Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), and nausea, stomach pain, indigestion. Most of these side effects of Dablexa 75 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Dablexa 75 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dablexa 75 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dablexa 75 Capsule . Try not to stop taking this medicine of your own. Stopping a sudden intake of Dablexa 75 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke.

Uses of Dablexa 75 Capsule

Prevention of stroke, Prevention of heart attack.

Medicinal Benefits

Dablexa 75 Capsule belongs to a class of drugs known as anticoagulants or blood thinner. It prevents clot formation in the deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain), and heart in patients with atrial fibrillation (irregular heart rhythm). Dablexa 75 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Dablexa 75 Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Directions for Use

Swallow Dablexa 75 Capsule as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dablexa 75 Capsule

  • Stomach pain
  • Indigestion
  • Bleeding
  • Anemia (low number of red blood cells)
  • Nausea
  • Diarrhea

Drug Warnings

If you are known to be allergic to Dablexa 75 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dablexa 75 Capsule . Safety and effectiveness of Dablexa 75 Capsule have not been established, so its use should be avoided in pediatric patients or children less than 18 years of age. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dablexa 75 Capsule . Try not to stop taking Dablexa 75 Capsule of your own. Stopping a sudden intake of Dablexa 75 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Hence, you should consult a doctor before stopping the dose of Dablexa 75 Capsule . You should inform the doctor that you are taking Dablexa 75 Capsule before any surgery is scheduled. Dablexa 75 Capsule can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Avoid consumption of alcohol while taking Dablexa 75 Capsule as it may increase the risk of stomach bleeding.

Drug Interactions

Drug-Drug Interactions: Dablexa 75 Capsule may interact with medicines to reduce blood clotting (warfarin, phenprocoumon, acenocoumarol, heparin, clopidogrel, prasugrel, ticagrelor, rivaroxaban), medicines to treat abnormal heartbeats  (amiodarone, dronedarone, quinidine, verapamil), medicines to treat fungal infections (ketoconazole, itraconazole), medicines to prevent organ rejection after transplantation (tacrolimus, cyclosporine) antiviral or HIV medicines (lopinavir, ritonavir, glecaprevir, pibrentasvir), antibiotics (rifampicin or clarithromycin), pain reliever (aspirin, ibuprofen, diclofenac), antiepileptic drugs (carbamazepine, phenytoin).

Drug-Food Interactions: Dablexa 75 Capsule may interact with St. John’s wort, herbal medicine for depression.

Drug-Disease Interactions: Use with caution in patients with kidney, liver, or bleeding problems, heart problems, and unstable blood pressure.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENPROCOUMON
  • ACENOCOUMAROL
  • HEPARIN
  • CLOPIDOGREL
  • PRASUGREL
  • TICAGRELOR
  • RIVAROXABAN
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • VERAMAPIL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • TACROLIMUS
  • CYCLOSPORINE
  • LOPINAVIR
  • RITONAVIR
  • GLECAPREVIR
  • PIBRENTASVIR
  • RIFAMPICIN
  • CLARITHROMYCIN
  • ASPIRIN
  • IBUPROFEN
  • DICLOFENAC
  • CARBAMAZEPINE
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Dablexa 75 Capsule .

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Special Advise

You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR, or international normalized ratio to analyze your blood clotting time.

Disease/Condition Glossary

A blood clot can occur in any part of the body that can lead to a heart attack, stroke, and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. On the other hand, deep vein thrombosis (blood clot in veins), peripheral artery disease (narrowed arteries due to fat deposit or blood clot), and atherosclerosis (fat build upon the walls of the arteries) can cause a blood clot in your limbs.

bannner image

Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dablexa 75 Capsule as it may increase the risk of bleeding.

bannner image

Pregnancy

Caution

Dablexa 75 Capsule is unsafe to use during pregnancy since it affects the foetus. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Dablexa 75 Capsule .

bannner image

Breast Feeding

Caution

There is limited data on how Dablexa 75 Capsule affects breastfeeding. However, it is unsafe to use Dablexa 75 Capsule if you are lactating, since it passes through the breast milk and harm the baby. Please consult your doctor before starting Dablexa 75 Capsule .

bannner image

Driving

Caution

Dablexa 75 Capsule usually does not affect your ability to drive or operate machinery.

bannner image

Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dablexa 75 Capsule . However, it is not recommended in patients with severe liver diseases.

bannner image

Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Dablexa 75 Capsule . However, it is not recommended in patients with severe kidney diseases.

bannner image

Children

Caution

Dablexa 75 Capsule is not recommended for children below the age of 18 years. The safety and efficacy of Dablexa 75 Capsule have not been established in children.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - DAB0395

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Dablexa 75 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation.
Please consult your doctor if Dablexa 75 Capsule needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Dablexa 75 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery. It also causes a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural). This type of blood clot could cause long-term paralysis.
Dablexa 75 Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. It is advisable, please consult your doctor and take Dablexa 75 Capsule for as long as your doctor has prescribed it.
Taking Dablexa 75 Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Dablexa 75 Capsule .
Dablexa 75 Capsule consists of Dabigatran is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.
No, you are not recommended to stop taking Dablexa 75 Capsule without consulting your doctor to worsen the condition. Therefore, take Dablexa 75 Capsule for as long as your doctor has prescribed it.
Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.
You can take Dablexa 75 Capsule with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.
Take Dablexa 75 Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take Dablexa 75 Capsule as long as your doctor has prescribed it for you.
You are recommended to avoid consumption of alcohol with Dablexa 75 Capsule as it may increase the risk of bleeding.
Hair loss is not a known side effect of Dablexa 75 Capsule . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor guide you on how to cope with this situation.
It varies from person to person and depends on the conditions that we treat.
Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dablexa 75 Capsule . However, it is not recommended in patients with severe liver diseases.
Store in a cool and dry place away from sunlight. Keep Dablexa 75 Capsule out of the sight and reach of children.
Yes, bleeding is the main risk associated with Dablexa 75 Capsule treatment; patients should be monitored for signs of bleeding.
Dablexa 75 Capsule is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Dablexa 75 Capsule .
Common side effects of Dablexa 75 Capsule may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Add to Cart