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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
D Rozavel 20 Tablet is used to lower raised cholesterol levels. This reduces the risk of heart attack and stroke in future. It contains Rosuvastatin and Cholecalciferol (vitamin D3), which decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. It helps in the absorption of calcium by the body. Some people may experience side effects such as nausea, headache, stomach pain, dizziness, weakness, muscle pain or constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Synonym

ROSUVASTATIN+VITAMIN D3

Manufacturer/Marketer

Synokem Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About D Rozavel 20 Tablet

D Rozavel 20 Tablet is used to lower raised cholesterol levels. This reduces the risk of heart attack and stroke in future. High cholesterol, known as hyperlipidaemia or dyslipidaemia, occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When the cholesterol level is high in the blood, your arteries get narrowed and clogged, contributing to heart diseases, like stroke and heart attack. Two cholesterol types are found in our body, namely, good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.

D Rozavel 20 Tablet is a combination of two drugs: Rosuvastatin (statin) and Cholecalciferol (vitamin D3). Rosuvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Cholecalciferol is vitamin D3 that helps in the absorption of calcium by the body and also relieves muscle pain caused by Rosuvastatin.

Take D Rozavel 20 Tablet as prescribed. Your doctor will advise you how often you take D Rozavel 20 Tablet based on your medical condition. Some people may experience nausea, headache, stomach pain, dizziness, weakness, muscle pain or constipation. Most of these side effects of D Rozavel 20 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to D Rozavel 20 Tablet or any other medicines, please tell your doctor. Avoid using D Rozavel 20 Tablet if you are pregnant or breastfeeding women, and consult a doctor before taking D Rozavel 20 Tablet . You are advised to take effective birth control measures while taking D Rozavel 20 Tablet to avoid pregnancy while taking D Rozavel 20 Tablet . Avoid taking D Rozavel 20 Tablet if you have liver disease, including abnormal liver enzyme tests. You recommend maintaining a time gap of 2 hours between taking D Rozavel 20 Tablet and antacids containing magnesium or aluminium. Taking these medicines together may reduce the absorption of D Rozavel 20 Tablet by antacid. If you have a thyroid disorder, severe respiratory failure, hypervitaminosis D (high levels of vitamin D in the body), hypercalcemia (high levels of calcium in the blood), electrolyte imbalance, kidney, liver, heart or muscle problems, please consult a doctor before taking D Rozavel 20 Tablet .

Uses of D Rozavel 20 Tablet

Treatment of Hyperlipidemia (high cholesterol), Prevention of heart attack and stroke.

Medicinal Benefits

D Rozavel 20 Tablet is a combination of two drugs, Rosuvastatin and Cholecalciferol, primarily used to lower bad cholesterol and triglyceride levels. Rosuvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Cholecalciferol is vitamin D3 that helps in the absorption of calcium by the body and also relieves muscle pain caused by Rosuvastatin.

Directions for Use

Take D Rozavel 20 Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of D Rozavel 20 Tablet

  • Nausea
  • Headache
  • Stomach pain
  • Dizziness
  • Weakness
  • Muscle pain
  • Constipation

Drug Warnings

If you are allergic to D Rozavel 20 Tablet or any other medicines, please tell your doctor. Avoid using D Rozavel 20 Tablet if you are pregnant or breastfeeding women and consult a doctor before taking D Rozavel 20 Tablet . You are advised to take effective birth control measures while taking D Rozavel 20 Tablet to avoid pregnancy while taking D Rozavel 20 Tablet . Maintain a low-fat diet along with D Rozavel 20 Tablet for effective results. Avoid taking D Rozavel 20 Tablet if you have liver disease, including abnormal liver enzyme tests. You recommend maintaining a time gap of 2 hours between taking D Rozavel 20 Tablet and antacids containing magnesium or aluminium. Taking these medicines together may reduce the absorption of D Rozavel 20 Tablet by antacid. If you have thyroid disorder, severe respiratory failure, hypervitaminosis D (high levels of vitamin D in the body), hypercalcemia (high levels of calcium in the blood), electrolyte imbalance, kidney, liver, heart or muscle problems, please consult a doctor before taking D Rozavel 20 Tablet .

Drug Interactions

Drug-Drug Interaction: D Rozavel 20 Tablet may have interaction with other medicines used to lower bad cholesterol (gemfibrozil, fenofibrate, ezetimibe), immunosuppressant (cyclosporine), blood thinners (clopidogrel, warfarin), antibiotics (fusidic acid, erythromycin), anticancer drugs (regorafenib, darolutamide) and antiviral drugs (sofosbuvir, voxilaprevir, ombitasvir, ritonavir, lopinavir, atazanavir, elbasvir, glecaprevir, pibrentasvir, paritaprevir, dasabuvir, velpatasvir, grazoprevir).

Drug-Food Interaction: D Rozavel 20 Tablet may interact with alcohol. Therefore, avoid alcohol consumption with D Rozavel 20 Tablet as it may increase the risk of liver problems.

Drug-Disease Interaction: If you have thyroid disorder, severe respiratory failure, hypervitaminosis D (high levels of vitamin D in the body), hypercalcemia (high levels of calcium in the blood), electrolyte imbalance, kidney, liver, heart or muscle problems, please consult a doctor before taking D Rozavel 20 Tablet .

Drug-Drug Interactions Checker List

  • GEMFIBROZIL
  • FENOFIBRATE
  • EZETIMIBE
  • CYCLOSPORINE
  • CLOPIDOGREL
  • WARFARIN
  • FUSIDIC ACID
  • ERYTHROMYCIN
  • DAROLUTAMIDE
  • RITONAVIR
  • LOPINAVIR
  • ATAZANAVIR
  • GLECAPREVIR
  • PIBRENTASVIR
  • PARITAPREVIR
  • VELPATASVIR
  • REGORAFENIB
  • SOFOSBUVIR
  • VOXILAPREVIR
  • OMBITASVIR
  • ELBASVIR
  • DASABUVIR
  • GRAZOPREVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.

  • Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts and cut down beverages, and processed and sugary foods.

  • Do regular exercises such as swimming, cycling, walking, or dancing and focus on losing weight as obesity also raises bad cholesterol and lowers good cholesterol.

  • Avoid smoking and alcohol consumption.

Special Advise

  • Regular blood tests are recommended while taking D Rozavel 20 Tablet to monitor cholesterol levels in the blood and liver functioning.

  • Regularly monitor blood sugar levels as D Rozavel 20 Tablet may increase the risk of developing diabetes, especially in patients who are overweight, have high blood pressure, or have high levels of fats and sugars in the blood.

Disease/Condition Glossary

High cholesterol, known as hyperlipidemia or dyslipidemia, occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol. There are two types of cholesterol found in our body: good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.

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Alcohol

Unsafe

Avoid consumption of alcohol with D Rozavel 20 Tablet as it may increase the risk of liver damage. Please consult a doctor before consuming alcohol with D Rozavel 20 Tablet .

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Pregnancy

Unsafe

D Rozavel 20 Tablet is a Category X pregnancy drug and is considered unsafe for pregnant women as it may cause harm to the unborn baby. So, if you are pregnant or planning for pregnancy, please inform your doctor before taking D Rozavel 20 Tablet .

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Breast Feeding

Unsafe

Avoid breastfeeding while taking D Rozavel 20 Tablet as it may be unsafe for the baby. However, please consult a doctor before taking D Rozavel 20 Tablet .

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Driving

Caution

D Rozavel 20 Tablet usually does not affect your ability to drive or operate machinery. However, if you feel dizzy after taking D Rozavel 20 Tablet , avoid driving or operate machinery.

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Liver

Caution

Please consult a doctor if you have any Liver diseases/conditions. D Rozavel 20 Tablet is usually not recommended in patients with liver disease.

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Kidney

Caution

Take D Rozavel 20 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. D Rozavel 20 Tablet is not recommended in patients with severe kidney problems.

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Children

Caution

D Rozavel 20 Tablet is not recommended for children below 6 years of age. However, D Rozavel 20 Tablet should be used with caution in children above 6 years if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - DRO0138

Author Details

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FAQs

D Rozavel 20 Tablet is used to lower raised cholesterol levels. This reduces the risk of heart attack and stroke in future.
D Rozavel 20 Tablet contains Rosuvastatin and Cholecalciferol. Rosuvastatin works by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Cholecalciferol is vitamin D3 that helps in the absorption of calcium by the body and also relieves muscle pain caused by Rosuvastatin.
You are not recommended to take D Rozavel 20 Tablet with fusidic acid as co-administration of these two medicines may lead to a severe muscle problem known as rhabdomyolysis (the breakdown of muscle tissue). Therefore, inform your doctor if you have taken fusidic acid in the last 7 days before taking the D Rozavel 20 Tablet . You may be advised to stop taking D Rozavel 20 Tablet if you need to take fusidic acid. However, please consult a doctor before taking D Rozavel 20 Tablet with any other medicines.
D Rozavel 20 Tablet should be used with caution in diabetic patients as it may increase blood sugar levels. Regular monitoring of blood sugar levels is recommended in diabetic patients and inform your doctor before taking D Rozavel 20 Tablet if you are diabetic.
You are recommended to avoid eating foods rich in fat or cholesterol and caffeine as it may increase side effects.
Yes, D Rozavel 20 Tablet may cause rhabdomyolysis (the breakdown of muscle tissue) and may lead to kidney failure in some patients. It is not necessary for everyone taking D Rozavel 20 Tablet to experience this adverse effect. However, if you experience unexplained muscle pain, weakness or tenderness, especially along with fever, dark coloured urine or unusual tiredness, please consult your doctor immediately.
No, you are not recommended to stop taking D Rozavel 20 Tablet without consulting your doctor as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take D Rozavel 20 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking D Rozavel 20 Tablet , please consult your doctor so that the dose may be gradually reduced.

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