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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:21 PM IST
Cytonac ER Capsule is used to treat signs and symptoms of osteoarthritis or rheumatoid arthritis. It contains Aceclofenac and Misoprostol which work by inhibiting the chemical messengers that cause pain and protecting the stomach lining from the acid. In some cases, this medicine may cause side effects such as nausea, vomiting, dizziness, indigestion, stomach pain, diarrhoea, and constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Delvin Formulations (P) Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Cytonac ER Capsule

Cytonac ER Capsule belongs to the class of 'painkillers' primarily used to treat signs and symptoms of osteoarthritis or rheumatoid arthritis in patients at high risk of developing pain killer-induced gastric and duodenal ulcers and their complications. Rheumatoid arthritis is an autoimmune disease in which the body's immune system attacks its own cells and causes joint pain with inflammation. 

Cytonac ER Capsule is a combination of two drugs: Aceclofenac and Misoprostol. Aceclofenac belongs to the class of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs) that cause pain and swelling at the injured or damaged site. Misoprostol is a prostaglandin analogue that belongs to the class of anti-ulcer agents. It helps prevent ulcers caused by Aceclofenac by protecting the stomach lining and decreasing the acid production in the stomach.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Cytonac ER Capsule include nausea, vomiting, dizziness, indigestion, stomach pain, diarrhoea, constipation, and heartburn. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.

Before starting Cytonac ER Capsule , inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, and fluid retention. Cytonac ER Capsule is not recommended during pregnancy and breastfeeding. Cytonac ER Capsule may cause dizziness, so drive only if you are alert and focused. Cytonac ER Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Cytonac ER Capsule as it could lead to increased dizziness and risk of stomach bleeding/ulcers. 

Uses of Cytonac ER Capsule

Treatment of Osteoarthritis and Rheumatoid arthritis.

Medicinal Benefits

Cytonac ER Capsule treats pain, redness, and inflammation (swelling) in patients suffering from osteoarthritis and rheumatoid arthritis. It contains Aceclofenac and Misoprostol. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser PGs are made, which reduces mild to moderate pain and inflammation at the injured or damaged site. Misoprostol is a prostaglandin analogue and an anti-ulcer agent. Prostaglandins produced in the stomach and intestine protect the lining. Misoprostol helps prevent ulcers caused by Aceclofenac by protecting the stomach lining and decreasing the acid production in the stomach. 

Directions for Use

Swallow it as a whole with a glass of water; do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cytonac ER Capsule

  • Abdominal pain
  • Diarrhoea
  • Dyspepsia
  • Nausea
  • Flatulence
  • Gastritis
  • Vomiting
  • Constipation
  • Headache
  • Dizziness
  • Increased liver enzyme

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, blood disorders like porphyria, and fluid retention before starting Cytonac ER Capsule . Do not take any other NSAID's for pain relief along with Cytonac ER Capsule unless prescribed. Stop taking Cytonac ER Capsule and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Cytonac ER Capsule is not recommended for pregnant and breastfeeding women. Misoprostol in Cytonac ER Capsule is an abortion drug and can cause congenital disabilities, miscarriage, premature labour, or rupture of the uterus in pregnancy. Cytonac ER Capsule may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol, and Cytonac ER Capsule as it could lead to increased dizziness and risk of stomach bleeding/ulcers. Cytonac ER Capsule is not recommended in children as safety and efficacy is not established. 

Drug Interactions

Drug-Drug Interaction: Cytonac ER Capsule may interact with pain killers (aspirin, ibuprofen, naproxen, celecoxib, ketorolac), blood thinners (warfarin, clopidogrel, dabigatran, enoxaparin), blood pressure medicines (aliskiren, captopril, lisinopril, valsartan, losartan), antivirals (cidofovir), anti-depressants (lithium), anti-cancer drugs (methotrexate), water pills (furosemide), and corticosteroids (dexamethasone, prednisone).

Drug-Food Interaction: Alcohol consumption may cause dizziness and increases the risk of stomach ulcers and bleeding.

Drug-Disease Interaction: Cytonac ER Capsule should be used with caution in cases of stomach ulcers, blood disorders, blood circulation problems to the brain, asthma, porphyria, diabetes, high blood pressure, autoimmune diseases, connective tissue diseases, heart, kidney, and liver problems.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • NAPROXEN
  • CELECOXIB
  • KETOROLAC
  • WARFARIN
  • CLOPIDOGREL
  • ENOXAPARIN
  • DABIGATRAN
  • ALISKIREN
  • CAPTOPRIL
  • LISINOPRIL
  • VALSARTAN
  • LOSARTAN
  • CIDOFOVIR
  • LITHIUM
  • METHOTREXATE
  • FUROSEMIDE
  • DEXAMETHASONE
  • PREDNISONE

Habit Forming

No

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes. Instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated; drink plenty of water.

Special Advise

  • Cytonac ER Capsule may cause fluid retention (oedema); hence it is advised to monitor blood pressure and cardiovascular status (ECG) in patients with a heart failure history. 
  • The use of pain killers (NSAIDs) is associated with reversible infertility, so it is advisable to stop the intake of Cytonac ER Capsule  in women who have difficulties conceiving. 
  • Use of Cytonac ER Capsule in pregnant women can cause abortion, congenital disabilities, premature birth or uterine rupture due to misoprostol.
  • There is a high risk of developing gastric or duodenal ulcers associated with using the Cytonac ER Capsule due to pain killers (NSAIDs) like diclofenac, aceclofenac, etc. So in this case of a gastrointestinal ulcer or bleeding stop taking Cytonac ER Capsule and consult a doctor. 

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age. The older you are, the more likely you could get osteoarthritis. Hence, it is known as a degenerative disease since the joints wear out as a person ages. Other reasons include a past injury, such as torn cartilage, dislocated joints, and ligament injuries.

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function. 

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Cytonac ER Capsule . Alcohol intake, along with Cytonac ER Capsule , may cause increased dizziness and risk of stomach bleeding/ulcers.

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Pregnancy

Unsafe

Misoprostol in Cytonac ER Capsule is used for medical abortion. If taken in pregnancy, Cytonac ER Capsule can lead to birth defects, miscarriage, premature labour, or rupture of the uterus.

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Breast Feeding

Unsafe

Cytonac ER Capsule is not recommended for use during breastfeeding since it passes into the breast milk.

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Driving

Caution

Cytonac ER Capsule may make you feel dizzy and sleepy. Do not drive or operate machinery if you experience dizziness or drowsiness.

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Liver

Caution

Please consult your doctor since Cytonac ER Capsule should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Please consult your doctor since Cytonac ER Capsule should be used with caution in patients with kidney impairment/kidney disease.

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Children

Unsafe

Cytonac ER Capsule is not recommended in children younger than 12 years of age.

Country of origin

INDIA

Manufacturer/Marketer address

Kerom 3rd Floor Plot No A112, Near State Bank of India Road No 22, Wagle Industrial Estate Thane (W) Pin: 400604
Other Info - CYT0074

Author Details

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FAQs

Cytonac ER Capsule is used to treat osteoarthritis or rheumatoid arthritis.
Cytonac ER Capsule contains Aceclofenac and Misoprostol. It works by blocking certain chemical messengers that cause pain and inflammation at the injured or damaged site. Misoprostol helps prevent the stomach and intestinal ulcers triggered due to Aceclofenac (pain killers).
Cytonac ER Capsule is usually prescribed for a short period and can be discontinued if there is no pain. To treat your condition effectually continue taking Cytonac ER Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Cytonac ER Capsule .
Cytonac ER Capsule is to be carefully administered with caution in patients with liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, and fluid retention. Please consult your doctor before starting Cytonac ER Capsule if you have any other medical concerns.
Diarrhoea can be a side-effect of Cytonac ER Capsule . Drink enough fluids and eat fibre rich food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.
It is not advised to use other NSAIDs or pain killers while using Cytonac ER Capsule . Please seek medical advice for further information.
Cytonac ER Capsule can make your skin more sensitive to the harmful effects of sunlight. Hence it is advised to use sunscreen and wear protective clothing while using Cytonac ER Capsule . It is also recommended to avoid tanning booths and sunlamps.
No, Cytonac ER Capsule is not recommended for treating headaches. It is primarily used for managing pain associated with conditions like rheumatoid arthritis, osteoarthritis, and spondylitis.
Cytonac ER Capsule can cause a decrease in body weight as a side effect due to loss of appetite. However, follow a balanced diet to overcome this side effect. If you have any concerns, consult your doctor.
The common side effects of Cytonac ER Capsule are nausea, vomiting, dizziness, indigestion, stomach pain, diarrhoea, constipation, and heartburn. If any of these side effects persist or worsen, please consult your doctor.

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