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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 9:32 AM IST

Cyramza 500 Injection is used for treating Colorectal Cancer, Stomach Cancer, Hepatocellular cancer and Non-small cell lung cancer. It contains Ramucirumab as an active ingredient, which belongs to the class of monoclonal antibodies. It works by inhibiting the abnormal growth of cancer cells and, finally, causes the initiation of programmed cell death. Thus, it treats certain cancers. Cyramza 500 Injection may cause side effects, such as abdominal pain, dry mouth, mouth sores, increased blood pressure, diarrhoea, fatigue, nausea, headache, nose bleeds, vomiting, tiredness, and injection site reactions.

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Prescription drug

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Composition :

RAMUCIRUMAB-500MG

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Cyramza 500 Injection

Cyramza 500 Injection is an anti-cancer medicine used alone or in combination with other combination medicines for the treatment of metastatic gastric or gastroesophageal junction adenocarcinoma, hepatocellular cancer, colorectal cancer, and non-small cell lung cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. It can also be used when the cancer has spread to other parts of the body.

Cyramza 500 Injection contains Ramucirumab as an active ingredient, which belongs to the class of monoclonal antibodies. It works by inhibiting the abnormal growth of cancer cells and, finally, causes the initiation of programmed cell death.

Cyramza 500 Injection may cause some side effects, such as abdominal pain, dry mouth, mouth sores, increased blood pressure, diarrhoea, fatigue, nausea, headache, nose bleeds, vomiting, tiredness, and injection site reactions. If the side effects persist or bother you, please consult your doctor. Cyramza 500 Injection will be administered by a doctor experienced in the administration of cancer medicine. Do not self-administer.

Avoid taking it and inform your doctor if you are allergic to Cyramza 500 Injection or its components. Inform your doctor if you have any cardiovascular conditions, heart attack, stroke, increased blood pressure, any planned surgery, lung problems, or liver/kidney disease, as it can cause adverse effects. Cyramza 500 Injection is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

Uses of Cyramza 500 Injection

Treatment of Colorectal Cancer, Stomach Cancer, Hepatocellular cancer and Non-small cell lung cancer

Medicinal Benefits

Cyramza 500 Injection contains Trastuzumab, which is used for treating patients with different types of cancer. This medicine works by inhibiting the excess production of a human vascular endothelial growth factor receptor 2, which is responsible for the growth and spread of cancer cells. This causes inhibition of the cancer cell growth and, finally, initiation of programmed cell death.

Side Effects of Cyramza 500 Injection

  • Nausea
  • Vomiting
  • Diarrhoea
  • Nose bleeds
  • Headache
  • Fatigue
  • Injection site reactions
  • Pain at the site of injection
  • Increased blood pressure
  • Dry mouth
  • Mouth sores
  • Fever
  • Back pain

Directions for Use

A doctor who is trained or experienced in the administration of chemotherapeutic agents will administer Cyramza 500 Injection. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Cyramza 500 Injection should be avoided if you are allergic to it or any other components of this medicine. Before taking Cyramza 500 Injection, inform your doctor if you have any history of cardiovascular conditions, heart attack, stroke, increased blood pressure, any planned surgery, lung problems, or liver or kidney disease, as it can cause adverse effects. Cyramza 500 Injection may cause Cyramza 500 Injection may cause reversible posterior leukoencephalopathy syndrome, arterial thromboembolic events, hypertension, an increased risk of hemorrhage, infusion-related reactions, gastrointestinal perforation, and clinical deterioration in patients with cirrhosis during the treatment. Hence, careful observation should be performed for any reactions in the patient. Cyramza 500 Injection may cause embryo-fetal toxicity. Hence, if you are pregnant or planning to become pregnant, inform your doctor beforehand. Breastfeeding should be discontinued in nursing mothers during the treatment. Cyramza 500 Injection is not recommended for use in children as the safety and efficacy are not established.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

verifiedApollotooltip
RamucirumabDiclofenac
Severe
RamucirumabApixaban
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

How Cyramza 500 Injection Works

Cyramza 500 Injection contains Ramucirumab as an active ingredient, which belongs to the class of monoclonal antibodies. It works by inhibiting the abnormal growth of cancer cells and, finally, causes the initiation of programmed cell death.

What if I have taken an overdose of Cyramza 500 Injection

As Cyramza 500 Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.
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Alcohol

Caution

It is unknown whether Cyramza 500 Injection interacts with alcohol. Consult your doctor for more information.

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Pregnancy

Unsafe

Cyramza 500 Injection is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Cyramza 500 Injection. You should not become pregnant while you are receiving Cyramza 500 Injection for at least three months from the last dose of Cyramza 500 Injection. Using effective birth control methods while on treatment is suggested.

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Breast Feeding

Unsafe

Cyramza 500 Injection should not be taken if you are breastfeeding as it passes into breast milk and may harm your infant. Avoid nursing your child while on treatment with this medicine and for at least two months from the last dose of medicine.

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Driving

Caution

Cyramza 500 Injection will be administered to hospitalized patients. Driving is not recommended.

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Liver

Safe if prescribed

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Cyramza 500 Injection. Based on population PK analysis, no dose adjustment is advised for patients with mild liver impairment. Patients with Child-Pugh B or C cirrhosis who received single-agent Cyramza 500 Injection reported clinical deterioration.

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Kidney

Safe if prescribed

Hence, if you have a pre-existing or a history of kidney disease, inform your doctor. Based on population PK analysis, no dose adjustment is advised for patients with kidney impairment.

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Children

Unsafe

Cyramza 500 Injection is not recommended for use in children as the safety and efficacy are not established.

Country of origin

India

Manufacturer/Marketer address

Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, Haryana, India
Other Info - CYR0011

Author Details

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FAQs

Cyramza 500 Injection is used to treat Colorectal Cancer, Stomach Cancer, Hepatocellular cancer and Non-small cell lung cancer.
Cyramza 500 Injection contains Ramucirumab, which works by inhibiting the abnormal growth of cancer cells and, finally, causes the initiation of programmed cell death.
Inform your doctor whether you have received any other cancer treatment. Cyramza 500 Injection may cause reversible posterior leukoencephalopathy syndrome, arterial thromboembolic events, hypertension, infusion-related reactions, gastrointestinal perforation, and embryo-fetal toxicity during the treatment. Hence, inform your oncologist if you have any cardiovascular conditions, liver/kidney disease, lung problems, are pregnant, are planning to become pregnant, or are breastfeeding before receiving Cyramza 500 Injection.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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