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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cycloxan Tablet is used to treat cancer and nephrotic syndrome (kidney disease). It contains Cyclophosphamide that stops the growth and multiplication of cancer cells. In some cases, this medicine may cause side effects such as fever, nausea, vomiting, diarrhoea, hair loss, low blood cell count, and abdominal pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Cycloxan Tablet

Cycloxan Tablet is used to treat malignant diseases such as lymphoma (Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt’s lymphoma, mycosis fungoide), leukaemia,  nerve tissue cancer, eye cancer, ovarian cancer, soft tissue cancer, bone cancer, and breast cancer. Additionally, Cycloxan Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
Cycloxan Tablet contains ‘Cyclophosphamide’, an alkylating agent that damages the genetic material of cancer cells to stop their growth and multiplication. Thus, Cycloxan Tablet helps treat cancer by killing the cancer cells.
 
You are advised to take Cycloxan Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fever, nausea, vomiting, diarrhoea, hair loss, low blood cell count, and abdominal pain. Do not be reluctant to talk with your doctor if you experience any of these side effects persistently.
 
Do not take Cycloxan Tablet if you are allergic to any of its components; or if you have bladder obstruction or other urination problems. Avoid taking Cycloxan Tablet if you are pregnant or breastfeeding. Cycloxan Tablet may cause dizziness, so drive only if you are alert. Cycloxan Tablet should be given to children only if prescribed by the doctor. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Cycloxan Tablet

Cycloxan Tablet is used to treat Cancer and nephrotic syndrome (kidney disease).

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew it.Oral liquid: Check the label for directions before use and take the prescribed dose using the dosing syringe or medicine spoon.

Medicinal Benefits

Cycloxan Tablet belongs to the group of anti-cancer medicines used to treat malignant diseases such as Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma(cancer of plasma cells), Burkitt’s lymphoma, leukaemia (blood cancer), neuroblastoma (nerve tissue cancer), retinoblastoma (eye cancer), adenocarcinoma of the ovary (ovarian cancer), mycosis fungoides (T-cell lymphoma), rhabdomyosarcoma (soft tissue cancer), osteosarcoma (bone cancer), and breast carcinoma. Additionally, Cycloxan Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in pediatric patients. Cycloxan Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Cycloxan Tablet helps to treat cancer by killing the cancer cells.

How Cycloxan Tablet Works

Cycloxan Tablet contains ‘Cyclophosphamide’, an alkylating agent that damages the genetic material of cancer cells to stop their growth and multiplication. Thus, Cycloxan Tablet helps treat cancer by killing the cancer cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cycloxan Tablet

  • Fever
  • Nausea
  • Vomiting
  • Diarrhoea
  • Hair loss
  • Low blood cell count
  • Abdominal pain

What if I have taken an overdose of Cycloxan Tablet

Take Cycloxan Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include black/tarry stools, red urine, unusual bleeding/bruising, unusual tiredness/weakness, signs of infection (sore throat, cough, fever), chest pain, and swelling in the ankles, feet or legs. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Cycloxan Tablet if you are allergic to any of its contents; or have urinary flow obstruction, bone marrow suppression, or infections. Talk to your doctor if you have myelosuppression, immunosuppression, infections, diabetes, heart, lung, liver, or kidney problems. Inform your doctor if you are receiving any radiotherapy or chemotherapy. Avoid taking Cycloxan Tablet if you are pregnant or breastfeeding. Cycloxan Tablet may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Drug-Drug Interactions

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CyclophosphamideNalidixic acid
Critical
CyclophosphamideCidofovir
Critical

Drug-Drug Interactions

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CyclophosphamideNalidixic acid
Critical
How does the drug interact with Cycloxan Tablet 10's:
Co-administration of Nalidixic acid with Cycloxan Tablet 10's may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Cycloxan Tablet 10's and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
CyclophosphamideCidofovir
Critical
How does the drug interact with Cycloxan Tablet 10's:
Co-administration of Cycloxan Tablet 10's and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor
CyclophosphamideTenofovir alafenamide
Severe
How does the drug interact with Cycloxan Tablet 10's:
Co-administration of Tenofovir alafenamide may cause kidney problems, and combining it with Cycloxan Tablet 10's may increase the risk.

How to manage the interaction:
Although there is a possible interaction, Cycloxan Tablet 10's can be taken with Tenofovir alafenamide if prescribed by the doctor. Consult the doctor if you develop signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop any medication without consulting a doctor.
CyclophosphamideFingolimod
Severe
How does the drug interact with Cycloxan Tablet 10's:
Taking Fingolimod's ability to suppress the immune system may be enhanced by Cycloxan Tablet 10's.

How to manage the interaction:
Although taking Cycloxan Tablet 10's and Fingolimod together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away - a serious infection, problems, high body temperature, feeling cold, loose stools, a painful throat, body discomfort, difficulty breathing, losing weight, or experiencing pain or discomfort while urinating. Do not stop using any medications without a doctor's advice.
CyclophosphamideInfliximab
Severe
How does the drug interact with Cycloxan Tablet 10's:
When Cycloxan Tablet 10's is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although taking Infliximab and Cycloxan Tablet 10's together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CyclophosphamideVoclosporin
Severe
How does the drug interact with Cycloxan Tablet 10's:
Co-administration of Cycloxan Tablet 10's with Voclosporin can increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Cycloxan Tablet 10's and Voclosporin, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much you pee. Some other signs to watch out for are feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, holding onto fluids, having a fever or chills, having diarrhea or a sore throat, feeling weak or dizzy, being confused, having trouble breathing, feeling pain or a burning sensation when you pee, or having an irregular heartbeat. Do not stop using any medications without talking to a doctor.
CyclophosphamideCladribine
Severe
How does the drug interact with Cycloxan Tablet 10's:
The combined use of Cladribine with Cycloxan Tablet 10's can increase the risk and severity of side effects.

How to manage the interaction:
Co-administration of Cladribine with Cycloxan Tablet 10's can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, contact a doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not discontinue any medications without consulting a doctor.
CyclophosphamideTofacitinib
Severe
How does the drug interact with Cycloxan Tablet 10's:
Taking Cycloxan Tablet 10's with Tofacitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Cycloxan Tablet 10's can be taken with Tofacitinib if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
CyclophosphamideTenofovir disoproxil
Severe
How does the drug interact with Cycloxan Tablet 10's:
Coadministration of Tenofovir disoproxil with Cycloxan Tablet 10's may increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction, Cycloxan Tablet 10's can be taken with Tenofovir disoproxil if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medication without consulting a doctor.
CyclophosphamideTeriflunomide
Severe
How does the drug interact with Cycloxan Tablet 10's:
Co-administration of Cycloxan Tablet 10's with Teriflunomide can increase the risk of side effects.

How to manage the interaction:
Although taking Cycloxan Tablet 10's and Teriflunomide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like fever, chills, sore throat, or muscle aches, it's best to contact a doctor right away. Other symptoms to watch out for include diarrhea, shortness of breath, weight loss, or pain during urination. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.
  • Stay protected from the sun. Avoid tanning beds and cover up with clothing, sunscreen, and sunglasses.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Cycloxan Tablet Substitute

Substitutes safety advice
  • Adcyclo 50 Tablet 10's

    3.51per tablet
  • Endoxan Tablet 10's

    3.83per tablet
  • Endoxan Tablet 10's

    3.83per tablet
  • Finoxamide Tablet 10's

    2.97per tablet
  • Phoscan 50mg Tablet

    3.37per tablet
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Alcohol

Consult your doctor

It is not known if alcohol affects Cycloxan Tablet . Please consult your doctor.

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Pregnancy

Unsafe

Cyclophosphamide belongs to pregnancy category D. Cycloxan Tablet should not be taken during pregnancy as it might cause fetal harm. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnant.

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Breast Feeding

Unsafe

Cycloxan Tablet passes into breastmilk. Avoid breastfeeding while taking Cycloxan Tablet .

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Driving

Caution

Cycloxan Tablet may cause dizziness. Drive or operate heavy machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Cycloxan Tablet should be used with caution in patients with renal impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Cycloxan Tablet should be given to children only if prescribed by a doctor.

FAQs

Cycloxan Tablet is used to treat malignant diseases such as lymphoma (Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt’s lymphoma, mycosis fungoide), leukaemia, nerve tissue cancer, eye cancer, ovarian cancer, soft tissue cancer, bone cancer, and breast cancer. Additionally, Cycloxan Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
Cycloxan Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Cycloxan Tablet helps to treat cancer by killing the cancer cells.
Do not stop taking Cycloxan Tablet on your own. You are advised to take Cycloxan Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Cycloxan Tablet .
Cycloxan Tablet might interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm) and could impair fertility. Before starting treatment with Cycloxan Tablet , talk to your doctor regarding cryopreservation/freezing of eggs/sperm if you consider becoming parents.
Cycloxan Tablet might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding, or bruising or if the wounds do not heal properly.
No, it is not safe to father a child while taking Cycloxan Tablet . Use effective contraception while taking Cycloxan Tablet and for at least four months after treatment. Women of childbearing age taking Cycloxan Tablet should use highly effective contraceptives while taking Cycloxan Tablet up to 1 year after the treatment.
Cycloxan Tablet might cause myelosuppression/bone marrow suppression leading to a decrease in white blood cells. This could lead to an increased risk of infections. Regular blood tests while taking Cycloxan Tablet are advised.
During treatment with Cycloxan Tablet , stay protected from sun and avoid excessive sun exposure. It’s best to use sunscreen, sunglasses and protective clothing to prevent skin damage, if your immune system is weakened.
Cancer treatments like chemotherapy and radiation therapy can increase the chance of developing other cancers, which may appear years after treatment with Cycloxan Tablet . The use of Cycloxan Tablet is associated with a higher risk of bladder cancer. Rarely, it may also increase the risk of other cancers like acute leukaemia, and ureter cancer.
Cycloxan Tablet is a chemotherapy medicine which belongs to the class of alkylating agents. It works by destroying cancer cells.
Yes, Cycloxan Tablet may be used to treat nephrotic syndrome in children, especially in cases where the condition has not improved, or has recurred after using other medications. It is also an option for children who have experienced severe side effects from other treatments. However, its safety and effectiveness for nephrotic syndrome in adults have not been established.
Cycloxan Tablet may cause weight loss due to decreased appetite and may be due to underlying cancer. Consult a doctor if you experience significant weight loss.
Cycloxan Tablet may cause side effects such as fever, nausea, vomiting, diarrhoea, hair loss, low blood cell count, and abdominal pain. However, if these side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Biochem Pharma, Lg 113 / A, Xth Central Mall, Mahavir Nagar, 90Ft Road, Next To D Mart, Kandivali - West, Mumbai - 400067.
Other Info - CYC0025

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