CRIFOS 4GM INJECTION belongs to a class of drugs called antibiotics used in the treatment of bacterial infections. CRIFOS 4GM INJECTION is used to treat bacterial meningitis (infection of membranes protecting the brain and spinal cord), complicated urinary tract infections, bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues below the skin. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly.

CRIFOS 4GM INJECTION contains Fosfomycin which works by inhibiting the formation of the bacterial cell walls (a protective covering) that is necessary for their survival. Thereby killing bacteria. Also, CRIFOS 4GM INJECTION decreases the attachment of bacteria to cells lining the urinary bladder.

CRIFOS 4GM INJECTION will be administered by a healthcare professional. Do not self-administer. You may sometimes experience gastrointestinal disturbances, taste disturbances, or injection site reactions. Most of these side effects of CRIFOS 4GM INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Fosfomycin or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking CRIFOS 4GM INJECTION. CRIFOS 4GM INJECTION could be used in children if prescribed by a doctor; the dose depends on the child’s age and weight. If you have experienced diarrhoea after receiving or taking antibiotics, inform your doctor before taking CRIFOS 4GM INJECTION. If you have kidney problems or are undergoing dialysis, inform your doctor as the dose may be reduced. 

CRIFOS 4GM INJECTION contains Fosfomycin, a broad-spectrum antibiotic that kills gram-negative and gram-positive bacteria that grow aerobically (in the presence of oxygen) and anaerobically (in the absence of oxygen). Bacterial meningitis (infection of the membranes that protect the brain and spinal cord), complicated urinary tract infections, bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues beneath the skin are all treated with CRIFOS 4GM INJECTION. Fosfomycin should be used only when other antibiotics have failed or are ineffective. CRIFOS 4GM INJECTION prevents bacterial cell wall formation (a protective covering required for survival). Bacteria are thus killed. Additionally, CRIFOS 4GM INJECTION reduces the attachment of bacteria to the cells lining the urinary bladder.

• Taste disturbances
• Gastrointestinal disturbances
• Injection site reactions

If you are allergic to Fosfomycin or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking CRIFOS 4GM INJECTION. CRIFOS 4GM INJECTION may be used with caution in children if prescribed by a doctor; the dose depends on the child’s age and weight. If you had diarrhoea previously after receiving or taking antibiotics, inform your doctor before taking CRIFOS 4GM INJECTION. If you have kidney problems or are undergoing dialysis, inform your doctor, as the dose may be reduced. 

Drug-Drug Interaction: CRIFOS 4GM INJECTION may interact with anticoagulants (blood thinners).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have high blood pressure, hypernatraemia (high levels of sodium in the blood), hyperaldosteronism (excessive production of aldosterone hormone), pulmonary oedema (accumulation of fluid in the lungs), kidney or heart problems or if had diarrhoea previously after receiving or taking antibiotics, inform your doctor before taking CRIFOS 4GM INJECTION.

• Take probiotics after completing the full course of CRIFOS 4GM INJECTION in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can help restore the intestine's good bacteria. 

• Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet. 

• Maintain a low-sodium diet as CRIFOS 4GM INJECTION in injection form may increase sodium levels in the blood.

• Make sure you drink plenty of water or other fluids daily while you are taking CRIFOS 4GM INJECTION.

• The levels of electrolytes are regularly monitored while taking CRIFOS 4GM INJECTION as it may cause high sodium or low potassium levels in the blood.

Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiple very quickly. Bacteria come in three basic shapes, namely spherical, rod or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever and tiredness.