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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cpressin 40IU Injection is used in the treatment of Low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), Diabetes insipidus and to Control bleeding from esophageal varices. It contains Vasopressin, a human-made form of Vasopressin. When your body cannot produce enough Vasopressin, Cpressin 40IU Injection is used to replace it. It also helps treat diabetes insipidus by increasing the amount of water reabsorption from the kidneys. It helps to control bleeding from esophagal varices by increasing plasma levels of factor VIII activity in patients with bleeding disorders.

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Composition :

VASOPRESSIN-40I.U

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Cpressin 40IU Injection

Cpressin 40IU Injection belongs to the class of antidiuretic hormones. It is used to treat diabetes insipidus and to control bleeding from esophagal varices. It can also be used to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines. Diabetes insipidus is a rare form of diabetes, causing the production of large quantities of urine.

Cpressin 40IU Injection contains Vasopressin, a human-made form of Vasopressin (antidiuretic hormone). When your body cannot produce enough Vasopressin, Cpressin 40IU Injection is used to replace it. It also helps treat diabetes insipidus (a rare form of diabetes causing the production of large quantities of urine) by increasing the amount of water reabsorption from the kidneys. Cpressin 40IU Injection helps to control bleeding from esophagal varices by increasing plasma levels of factor VIII activity in patients with bleeding disorders. Besides this, Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.

Cpressin 40IU Injection will be administered by a healthcare professional; do not self-administer. The common side effects of Cpressin 40IU Injection include nausea, vomiting, fatigue, fast or irregular heart rate, hyponatremia (low blood sodium levels), ischemia (restriction in blood supply), and redness/pain/swelling at the injection site. These side effects may not occur in everyone using this medication and gradually resolve over time. If the side effects persist longer or worsen, please seek a doctor's advice.

Before starting Cpressin 40IU Injection, let your doctor know if you have any medical history of kidney impairment, cerebral vascular disorder, peripheral arterial disease, ischemic heart disease, congestive heart failure, seizures, asthma, fluid retention, or migraine. While using Cpressin 40IU Injection, avoid drinking large amounts of fluid, including alcohol, since it could lead to the build-up of water in the body. Inform your doctor if you are pregnant or breastfeeding. Cpressin 40IU Injection can cause water intoxication characterised by drowsiness, being uninterested in anything (listless) and headaches. If you notice any of these signs, seek immediate medical help. If it is not corrected, water intoxication can lead to fits or even coma.

Uses of Cpressin 40IU Injection

Treatment of Low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), Diabetes insipidus and to Control bleeding from esophageal varices

Directions for Use

A healthcare professional will administer it; do not self-administer.

Medicinal Benefits

Cpressin 40IU Injection contains Vasopressin, an antidiuretic (that controls fluid balance) hormone synthesized in the hypothalamus of the pituitary gland. When your body cannot produce enough Vasopressin, Cpressin 40IU Injection is used to replace it. It helps treat diabetes insipidus. (a rare form of diabetes causing the production of large quantities of urine). Vasopressin increases the amount of water absorbed back into your kidneys. Thus, it helps treat diabetes insipidus. Cpressin 40IU Injection increases plasma levels of factor VIII activity in patients with bleeding disorders. Thus, it helps to control bleeding from esophageal varices. Besides this, Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.

How Cpressin 40IU Injection Works

Cpressin 40IU Injection contains Vasopressin, a human-made form of Vasopressin (antidiuretic hormone). When your body cannot produce enough Vasopressin, Cpressin 40IU Injection is used to replace it. It also helps treat diabetes insipidus (a rare form of diabetes causing the production of large quantities of urine) by increasing the amount of water reabsorption from the kidneys. Cpressin 40IU Injection helps to control bleeding from esophagal varices by increasing plasma levels of factor VIII activity in patients with bleeding disorders. Besides this, Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cpressin 40IU Injection

  • Nausea
  • Vomiting
  • Fatigue
  • Fast or irregular heart rate
  • Hyponatremia (low blood sodium levels)
  • Ischemia (restriction in blood supply)
  • Redness/pain/swelling at the injection site

What if I have taken an overdose of Cpressin 40IU Injection

As Cpressin 40IU Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly

Drug Warnings

It is recommended not to use if you are allergic to vasopressin or any of the other ingredients present in Cpressin 40IU Injection or suffer from any diseases or conditions associated with your blood vessels, especially the blood vessels of your heart, suffer from a certain type of kidney disease called chronic nephritis with nitrogen retention (your doctor will advise you) or if you are intended to receive halogenated anaesthetic agents during surgical procedures. Caution and regular monitoring are essential while using Cpressin 40IU Injection if you have asthma, allergic conditions, migraine, epilepsy (fits), high blood pressure, heart or kidney disease, obstruction of the blood vessels of the heart, or undergone removal of the pituitary gland. So, before taking the Cpressin 40IU Injection, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. It may cause maternal adverse reactions like tonic uterine contractions. 

Drug-Drug Interactions

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Vasopressin (argipressin)Ziprasidone
Critical
Vasopressin (argipressin)Amisulpride
Severe

Drug-Drug Interactions

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Vasopressin (argipressin)Ziprasidone
Critical
How does the drug interact with Cpressin 40IU Injection:
Co-administration of Ziprasidone together with Vasopressin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Ziprasidone with Cpressin 40IU Injection together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Amisulpride
Severe
How does the drug interact with Cpressin 40IU Injection:
Using amisulpride together with vasopressin can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Amisulpride and Cpressin 40IU Injection can cause an interaction, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Vasopressin (argipressin)Chloroquine
Severe
How does the drug interact with Cpressin 40IU Injection:
Using chloroquine together with vasopressin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and vasopressin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Vasopressin (argipressin)Mifepristone
Severe
How does the drug interact with Cpressin 40IU Injection:
Co-administration of vasopressin with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking vasopressin with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Gatifloxacin
Severe
How does the drug interact with Cpressin 40IU Injection:
Taking Gatifloxacin and Vasopressin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Vasopressin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Hydroxychloroquine
Severe
How does the drug interact with Cpressin 40IU Injection:
The combined use of vasopressin and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of vasopressin and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Vasopressin (argipressin)Disopyramide
Severe
How does the drug interact with Cpressin 40IU Injection:
The combined use of Vasopressin and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Vasopressin and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Vasopressin (argipressin)Ceritinib
Severe
How does the drug interact with Cpressin 40IU Injection:
Taking Vasopressin with Ceritinib may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ceritinib and Cpressin 40IU Injection together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations make sure to contact a doctor. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Moxifloxacin
Severe
How does the drug interact with Cpressin 40IU Injection:
Using moxifloxacin together with vasopressin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Cpressin 40IU Injection, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your qt interval. If you have to use it at the same time as something else, make sure to be careful and have regular check-ups with your doctor. Do not stop using any medications without first talking to your doctor.
Vasopressin (argipressin)Sotalol
Severe
How does the drug interact with Cpressin 40IU Injection:
Using sotalol together with Cpressin 40IU Injection can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Cpressin 40IU Injection, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Reduce the amount of salt and protein in your diet, which will help your kidneys to produce less urine.
  • Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination. 
  • Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.
  • Optimal water intake is recommended to prevent dehydration due to excessive urination.

Habit Forming

No

Therapeutic Class

HORMONES
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Alcohol

Caution

Avoid consuming alcohol while on treatment with Cpressin 40IU Injection.

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Pregnancy

Caution

The safety of Cpressin 40IU Injection in pregnant women is unknown. Therefore, please inform your doctor if you are pregnant or expecting pregnancy; your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the treatment to the mother.

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Driving

Caution

Cpressin 40IU Injection usually does not interfere with your driving ability. Do not drive or operate machinery if you experience unmanageable side effects with Cpressin 40IU Injection.

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Liver

Caution

Limited information was available about using Cpressin 40IU Injection in patients with liver disease. Inform your doctor before receiving the Cpressin 40IU Injection if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Cpressin 40IU Injection is contraindicated in patients with severe kidney impairment. Please let your doctor know if you have any history of kidney diseases before receiving Cpressin 40IU Injection.

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Children

Unsafe

Cpressin 40IU Injection is not recommended in children below 18 years.

FAQs

Cpressin 40IU Injection is used to treat Low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), Diabetes insipidus and to Control bleeding from esophageal varices.
Cpressin 40IU Injection contains Vasopressin, a human-made form of Vasopressin (antidiuretic hormone). When your body cannot produce enough Vasopressin, Cpressin 40IU Injection is used to replace it. It helps treat diabetes insipidus. (a rare form of diabetes causing the production of large quantities of urine). Vasopressin increases the amount of water absorbed back into your kidneys. Thus, it helps treat diabetes insipidus.
Cpressin 40IU Injection increases plasma levels of factor VIII activity in patients with bleeding disorders.
Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.
Optimal intake of fluids is recommended to prevent dehydration. However, avoid excess intake of water and other liquids like coffee, tea, cola, and energy drinks during the treatment. Excessive fluid intake while using Cpressin 40IU Injection may lead to a build-up of water, which dilutes the salt in the body, leading to serious problems.
Generally, Cpressin 40IU Injection is administered through intramuscular (IM), intravenous (IV), and subcutaneous routes. However, a healthcare professional will administer it; do not self-administer Cpressin 40IU Injection.
Cpressin 40IU Injection is safe when used only under the doctor’s supervision. However, it may cause side effects like nausea, vomiting, fatigue, fast or irregular heart rate, hyponatremia (low blood sodium levels), ischemia (restriction in blood supply), and redness/pain/swelling at the injection site.
Cpressin 40IU Injection should not be taken by people who are allergic to any of its ingredients or have hypersensitivity to 8-L-arginine vasopressin or chlorobutanol.
Cpressin 40IU Injection should be taken during pregnancy only if the doctor has prescribed it. The doctor will prescribe this medication only if the benefits outweigh the risks. Therefore, please consult your doctor before taking Cpressin 40IU Injection if you are pregnant.
Cpressin 40IU Injection is effective in the treatment of low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), diabetes insipidus, and to control bleeding from oesophageal varices. However, its effectiveness may vary from person to person.
The common side effects of Cpressin 40IU Injection include nausea, vomiting, fatigue, fast or irregular heart rate, hyponatremia (low blood sodium levels), ischemia (restriction in blood supply), and redness/pain/swelling at the injection site. These side effects may not occur in everyone using this medication. However, if the side effects persist longer or worsen, please seek a doctor's advice.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - CPR0013

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