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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Cosala PR Powder Sachet 1 gm is used to treat Ulcerative colitis and Crohn's disease. It contains Mesalazine, an anti-inflammatory drug. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. This helps reduce inflammation (redness and swelling) in the intestines and relieves stomach pain or bleeding symptoms. Also, it may prevent further episodes of ulcerative colitis.

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Composition :

MESALAZINE-1000MG

Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Cosala PR Powder Sachet 1 gm

Cosala PR Powder Sachet 1 gm belongs to a class of drugs called 'anti-inflammatory drugs used to treat ulcerative colitis and Crohn’s disease. Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus.

Cosala PR Powder Sachet 1 gm contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Take Cosala PR Powder Sachet 1 gm as prescribed. You are advised to use Cosala PR Powder Sachet 1 gm for as long as your doctor has recommended it for you based on your medical condition. In some cases, you may experience diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). Most of these side effects of Cosala PR Powder Sachet 1 gm do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid taking Cosala PR Powder Sachet 1 gm if you are allergic to Mesalazine or any other medicines. Cosala PR Powder Sachet 1 gm should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Cosala PR Powder Sachet 1 gm. Avoid taking Cosala PR Powder Sachet 1 gm if you have severe kidney failure. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Cosala PR Powder Sachet 1 gm immediately and consult a doctor.

Uses of Cosala PR Powder Sachet 1 gm

Cosala PR Powder Sachet 1 gm is used to treat Ulcerative colitis and Crohn's disease

Directions for Use

Tablet: Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Granules: Empty the contents directly on the tongue and drink some water or orange juice. They can also be mixed with yoghurt and should be taken immediately without chewing on granules.Pellets: Check the label for directions before use and take it as advised by the doctor.

Medicinal Benefits

Cosala PR Powder Sachet 1 gm contains Mesalazine, an anti-inflammatory drug used in the treatment of ulcerative colitis and Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping in reducing inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Cosala PR Powder Sachet 1 gm may prevent further episodes of ulcerative colitis.

How Cosala PR Powder Sachet 1 gm Works

Cosala PR Powder Sachet 1 gm contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cosala PR Powder Sachet 1 gm

  • Diarrhoea
  • Stomach pain
  • Headache
  • Nausea
  • Vomiting
  • Flatulence (gas)

What if I have taken an overdose of Cosala PR Powder Sachet 1 gm

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Cosala PR Powder Sachet 1 gm may include nausea, vomiting, abdominal pain, fast or shallow breathing, ringing in the ears, headache, dizziness, confusion, and seizures. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are allergic to Mesalazine or any other medicines, please tell your doctor. Cosala PR Powder Sachet 1 gm should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Cosala PR Powder Sachet 1 gm. Avoid taking Cosala PR Powder Sachet 1 gm if you have severe kidney failure. Severe skin reactions such as toxic epidermal necrolysis (skin peeling and blistering) or Stevens-Johnson syndrome (a painful rash that spreads and blisters) can occur in some patients taking Cosala PR Powder Sachet 1 gm. Therefore, if you notice any skin reactions while taking Cosala PR Powder Sachet 1 gm, please consult a doctor immediately. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Cosala PR Powder Sachet 1 gm immediately and consult a doctor. Avoid taking Cosala PR Powder Sachet 1 gm if you have had blood abnormalities or kidney problems while taking other medicines such as Sulphasalazine.

Drug-Drug Interactions

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MesalazineCidofovir
Critical
MesalazineMetrizamide
Severe

Drug-Drug Interactions

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MesalazineCidofovir
Critical
How does the drug interact with Cosala PR Powder Sachet 1 gm:
Co-administration of Cosala PR Powder Sachet 1 gm with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Cosala PR Powder Sachet 1 gm with Cidofovir is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
MesalazineMetrizamide
Severe
How does the drug interact with Cosala PR Powder Sachet 1 gm:
Co-administration of Metrizamide with Cosala PR Powder Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Cosala PR Powder Sachet 1 gm with Metrizamide they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, dry, itchy skin, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineRanitidine
Severe
How does the drug interact with Cosala PR Powder Sachet 1 gm:
Co-administration of Ranitidine with Cosala PR Powder Sachet 1 gm can decrease the levels of Cosala PR Powder Sachet 1 gm, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Cosala PR Powder Sachet 1 gm with Ranitidine, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineTenofovir alafenamide
Severe
How does the drug interact with Cosala PR Powder Sachet 1 gm:
Co-administration of Tenofovir alafenamide with Cosala PR Powder Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
There is a possibility of interaction between Cosala PR Powder Sachet 1 gm with Tenofovir alafenamide, but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience increased or decreased urination, swelling, shortness of breath, bone pain, cramping in the muscles. Do not discontinue the medication without consulting a doctor.
MesalazineDeferasirox
Severe
How does the drug interact with Cosala PR Powder Sachet 1 gm:
Co-administration of Deferasirox with Cosala PR Powder Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possibility of interaction between Cosala PR Powder Sachet 1 gm and Deferasirox but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as increased or decreased urination, abrupt weight gain or loss, weakness, or dizziness. Do not discontinue the medication without consulting a doctor.
MesalazineIodamide
Severe
How does the drug interact with Cosala PR Powder Sachet 1 gm:
Co-administration of Iodamide with Cosala PR Powder Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalamine with Iodamine they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, itchy skin, shortness of breath, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineNizatidine
Severe
How does the drug interact with Cosala PR Powder Sachet 1 gm:
Co-administration of Nizatidine with Cosala PR Powder Sachet 1 gm can decrease the level or effect of Mesalamine by increasing gastric pH.

How to manage the interaction:
Although there may be a possible interaction between Cosala PR Powder Sachet 1 gm with Nizatidine, they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineIomeprol
Severe
How does the drug interact with Cosala PR Powder Sachet 1 gm:
Co-administration of Iomeprol with Cosala PR Powder Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Cosala PR Powder Sachet 1 gm and Iomeprol they can be taken together if your doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineOmeprazole
Severe
How does the drug interact with Cosala PR Powder Sachet 1 gm:
Co-administration of omeprazole with Cosala PR Powder Sachet 1 gm can decrease the effects of Cosala PR Powder Sachet 1 gm.

How to manage the interaction:
There could be a possible interaction between Cosala PR Powder Sachet 1 gm and omeprazole, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help in healing faster.
  • Include olive oil and omega-3 fatty acids. Eat more fibre-rich foods such as fruits and vegetables.
  • Limit dairy intake as your body may develop difficulty digesting certain dairy products when you are affected with Crohn’s disease, which leads to stomach cramps, diarrhoea or stomach upset.
  • Drink plenty of water to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Cosala PR Powder Sachet 1 gm Substitute

Substitutes safety advice
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    37.80per tablet
  • Asacus Sachet 1 gm

    44.60per tablet
  • Vegaz OD Sachet 1.66 gm

    47.70per tablet
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Alcohol

Caution

The interaction of alcohol with Cosala PR Powder Sachet 1 gm is unknown. If you have concerns, please discuss them with your doctor before taking Cosala PR Powder Sachet 1 gm.

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Pregnancy

Consult your doctor

Cosala PR Powder Sachet 1 gm is a Category B pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning for pregnancy before taking Cosala PR Powder Sachet 1 gm.

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Breast Feeding

Caution

Cosala PR Powder Sachet 1 gm should not be taken by breastfeeding mothers unless advised by the doctor. Granules form of Mesalazine may cause allergic reactions such as diarrhoea in newborn babies after breastfeeding. If this happens, discontinue breastfeeding.

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Driving

Safe

Cosala PR Powder Sachet 1 gm usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Please consult your doctor, if you have liver problems before using Cosala PR Powder Sachet 1 gm.

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Kidney

Caution

Cosala PR Powder Sachet 1 gm should be used with extreme caution in patients with mild to moderate kidney impairment. Avoid taking Cosala PR Powder Sachet 1 gm if you have severe kidney impairment.

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Children

Caution

Cosala PR Powder Sachet 1 gm is not recommended for children below six years. However, Cosala PR Powder Sachet 1 gm should be given to children only if recommended by a doctor.

FAQs

Cosala PR Powder Sachet 1 gm is used to treat Ulcerative colitis and Crohn's disease.
Cosala PR Powder Sachet 1 gm contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helps in reducing inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
You are not recommended to take Cosala PR Powder Sachet 1 gm with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Cosala PR Powder Sachet 1 gm with other medicines.
Yes, Cosala PR Powder Sachet 1 gm may cause kidney stones in some patients. It is not necessary for everyone taking Cosala PR Powder Sachet 1 gm to experience this side effect. However, if you notice blood in urine or pain in the sides of the stomach, please consult a doctor immediately. Drink adequate water while taking Cosala PR Powder Sachet 1 gm to prevent kidney stones.
Cosala PR Powder Sachet 1 gm should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Cosala PR Powder Sachet 1 gm.
Yes, Cosala PR Powder Sachet 1 gm may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Cosala PR Powder Sachet 1 gm to prevent dehydration.
You are advised to take Cosala PR Powder Sachet 1 gm for the duration prescribed by the doctor. Talk to the doctor if you have any concerns.
Do not discontinue Cosala PR Powder Sachet 1 gm without consulting your doctor. It is essential to keep taking your medicine even if you feel well as it helps control your condition.
No, Cosala PR Powder Sachet 1 gm is not addictive.
Side effects of Cosala PR Powder Sachet 1 gm include diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). If the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - COS0294

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