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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Corbis AM-5 Tablet is used to treat high blood pressure. It contains Amlodipine and Bisoprolol, which acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps in reducing the risk of having a stroke, heart attack, other heart problems, or kidney problems in the future. It may cause common side effects like headaches, feeling exhausted, and swollen ankles. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Corbis AM-5 Tablet

Corbis AM-5 Tablet is used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications.

Corbis AM-5 Tablet contains Amlodipine (calcium channel blocker) and Bisoprolol (beta blocker). Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol helps relax our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.

Take Corbis AM-5 Tablet with or without food as prescribed by your doctor with a full glass of water. You may have common side effects like headaches, feeling exhausted, and swollen ankles, which usually resolve after some time. Prolonged intake of Corbis AM-5 Tablet may lead to a lowering of blood pressure. So, you must closely monitor your blood pressure if you have ever had a stroke or heart attack or are currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor.

It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Do not take grapefruit or grapefruit juices with Corbis AM-5 Tablet as it can increase the concentration of Corbis AM-5 Tablet and worsen its side effects. Please inform your doctor if you have had an allergic reaction to Corbis AM-5 Tablet , are pregnant or planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, diabetes, heart valve problem or heart attack. Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body. Corbis AM-5 Tablet is prescribed to adults and children more than six years of age.

Uses of Corbis AM-5 Tablet

Treatment of High blood pressure (hypertension)

Directions for Use

Take Corbis AM-5 Tablet with or without food as advised by your doctor. Swallow the whole tablet with approximately a glass of water. Do not crush, chew, or break it. For better results, it is preferable to take Corbis AM-5 Tablet at the same time every day.

Medicinal Benefits

Corbis AM-5 Tablet is a combination of two medicines: Amlodipine and Bisoprolol, which together help in lowering raised blood pressure effectively. Amlodipine is a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol (beta blocker) helps relax our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.

How Corbis AM-5 Tablet Works

Corbis AM-5 Tablet contains Amlodipine (calcium channel blocker) and Bisoprolol (beta blocker). Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol helps relax our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Corbis AM-5 Tablet

  • Bradycardia (slow heart rate)
  • Increased blood potassium level
  • Cold extremities
  • Gastrointestinal disturbances, including nausea
  • Fatigue

What if I have taken an overdose of Corbis AM-5 Tablet

Do not take more than the prescribed dose of Corbis AM-5 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Don't stop taking Corbis AM-5 Tablet without talking to your doctor first. Stopping Corbis AM-5 Tablet abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use Corbis AM-5 Tablet if you have a very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. It should not be given to the children less than 12 years of age. Before taking Corbis AM-5 Tablet you should tell your doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problems (COPD, bronchitis, emphysema), low blood sugar level (hypoglycaemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome).

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineIdelalisib
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Corbis AM-5 Tablet:
Using Corbis AM-5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Corbis AM-5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Corbis AM-5 Tablet:
Coadministration of Corbis AM-5 Tablet and Idelalisib may raise Corbis AM-5 Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Corbis AM-5 Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineSimvastatin
Severe
How does the drug interact with Corbis AM-5 Tablet:
Taking simvastatin with Corbis AM-5 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Corbis AM-5 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
AmlodipineLemborexant
Severe
How does the drug interact with Corbis AM-5 Tablet:
Coadministration of lemborexant and Corbis AM-5 Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Corbis AM-5 Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Corbis AM-5 Tablet:
Using Corbis AM-5 Tablet and mitotane together may drastically lower Corbis AM-5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Corbis AM-5 Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Corbis AM-5 Tablet:
Coadministration of Corbis AM-5 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Corbis AM-5 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipinePrimidone
Severe
How does the drug interact with Corbis AM-5 Tablet:
Using Corbis AM-5 Tablet and primidone together may lower Corbis AM-5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Corbis AM-5 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineTizanidine
Severe
How does the drug interact with Corbis AM-5 Tablet:
Co-administration of Tizanidine and Corbis AM-5 Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Corbis AM-5 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineFosphenytoin
Severe
How does the drug interact with Corbis AM-5 Tablet:
When Corbis AM-5 Tablet is taken with Fosphenytoin, it may decrease the blood levels of Corbis AM-5 Tablet, which may make Corbis AM-5 Tablet less effective.

How to manage the interaction:
Although taking Corbis AM-5 Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
AmlodipineRifabutin
Severe
How does the drug interact with Corbis AM-5 Tablet:
Using Corbis AM-5 Tablet and rifabutin together may lower Corbis AM-5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Corbis AM-5 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+BISOPROLOL-5MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+BISOPROLOL-5MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit or grapefruit juice with Corbis AM-5 Tablet can increase the blood levels of amlodipine. Avoid or limit consumption of grapefruit juice.

Diet & Lifestyle Advise

  • Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
  • Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week, can help lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. Low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil can help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Corbis AM-5 Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Corbis AM-5 Tablet should not be taken until prescribed. Corbis AM-5 Tablet can have some harmful effects on the baby (foetus), Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Caution

Corbis AM-5 Tablet is usually not recommended in breastfeeding mothers. Limited human data available suggests that the drug does not do any significant harm to the baby. Consume only if benefits outweigh risks.

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Driving

Unsafe

It is not recommended to drive after taking Corbis AM-5 Tablet as it may occasionally cause drowsiness or fatigue.

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Liver

Caution

Corbis AM-5 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Corbis AM-5 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Corbis AM-5 Tablet is not recommended in children. The safety and efficacy of Corbis AM-5 Tablet in children have not yet been established.

FAQs

Corbis AM-5 Tablet is used to treat high blood pressure. It works by relaxing the blood vessels, reducing the workload on the heart, and making the heart more efficient at pumping blood throughout the body.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

Usually, Corbis AM-5 Tablet is prescribed for long-term or lifelong treatment for heart-related chronic conditions and disorders. You should follow the doctor's advice and take it until your doctor tells you to stop. Suddenly stop taking Corbis AM-5 Tablet may raise your blood pressure and increase your risk of heart attack.

Your doctor may probably tell you to stop taking Corbis AM-5 Tablet as it lowers blood pressure (hypotension) when combined with general anaesthesia before surgery. So, please inform your doctor before surgery if you are taking Corbis AM-5 Tablet .

If you have missed a dose of Corbis AM-5 Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place. If it is time for you to take your next dose, do not take both doses together. Take only one dose; taking a double dose of Corbis AM-5 Tablet will lead to low blood pressure.

Country of origin

India

Manufacturer/Marketer address

Unichem Laboratories Ltd., Unichem Bhavan, Prabhat Estate, Off S.V.Road, Jogeshwari (West), Mumbai – 400 102
Other Info - COR0541

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