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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Combimeg CFC Free Inhaler 120 MDI is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). It contains Salmeterol and Fluticasone, which relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Also, it acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways. It may cause common side effects such as nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Megma Healthcare Pvt Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

About Combimeg CFC Free Inhaler 120 MDI

Combimeg CFC Free Inhaler 120 MDI is a respiratory medication used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). Asthma is a breathing problem in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes).

Combimeg CFC Free Inhaler 120 MDI is a combination of two medicines: Salmeterol (bronchodilator) and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Your doctor will advise on how often you take Combimeg CFC Free Inhaler 120 MDI based on your medical condition. The common side effects of Combimeg CFC Free Inhaler 120 MDI include nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of Combimeg CFC Free Inhaler 120 MDI do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Brief your medical history to the doctor if you have heart, liver, kidney diseases, hypokalaemia (low potassium levels in the blood), hyperadrenocorticism (high levels of cortisol), eye disorders like cataract and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes before taking Combimeg CFC Free Inhaler 120 MDI. Therapy with nasal or inhaled corticosteroids like Fluticasone should be cautiously administered in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis since there are chances of developing a secondary infection. Please check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines.

Uses of Combimeg CFC Free Inhaler 120 MDI

Treatment of Chronic Obstructive Pulmonary Disease (COPD), Bronchitis, Asthma, and Emphysema.

Directions for Use

Inhaler: Hold the inhaler with the mouthpiece facing downwards. Form a tight seal by placing your lips around the mouthpiece. Start breathing slowly with your mouth and push down the inhaler once. Remove the inhaler and breathe normally.Rotacap/Transcap:Rotacap/Transcap is a capsule with powdered medication which is placed in Rotahaler. It is for inhalation only. Do not swallow the capsule. Rotahaler/Transhaler is a plastic inhalation device that releases the medication when you breathe. The capsule should be placed at the base of the rotahaler/transhaler and completely twist the mouthpiece until you hear a click sound. Then, breathe in through the mouthpiece deeply and hold your breath for 10 seconds. Remove the device and breathe out normally.Respicap/Instacaps: Please read the instruction leaflet before usage and use in the dose and duration suggested by your doctor.Autohaler: Autohaler is a breath-activated device that releases the medication when you inhale. Shake the autohaler well before using it. Hold it upright and push the lever up. Place the mouthpiece in your mouth and seal your lips around it. Breathe in slowly and deeply to release the medication from the device. Hold your breath for 10 seconds and breathe out normally. Push the lever down and replace the cap.Inhalation Capsule: The capsule is meant for inhalation only; do not swallow the capsule. Check the instructions leaflet before use. Place it at the base of the inhaler and twist the mouthpiece until you hear a click sound. Breathe deeply through the mouthpiece and hold your breath for 10 seconds.Oral inhalation (Powder): Check the label for directions to use. Inhale the powder by mouth using an inhaler.Rotadisk: Rotadisk is a silver-coloured aluminium foil disk that contains four blisters to place the medication. The medicine is to be inhaled through the mouth from the Rotadisk using a plastic device called Diskhaler.

Medicinal Benefits

Combimeg CFC Free Inhaler 120 MDI is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). Combimeg CFC Free Inhaler 120 MDI improves pulmonary function and effectively treats and prevents the worsening of emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Combimeg CFC Free Inhaler 120 MDI is a combination of Salmeterol (bronchodilator) and Fluticasone (corticosteroid). Salmeterol relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways. Fluticasone has potent vasoconstrictive (narrowing of the blood vessels) and anti-inflammatory activity.

How Combimeg CFC Free Inhaler 120 MDI Works

Combimeg CFC Free Inhaler 120 MDI is a combination of two medicines: Salmeterol (bronchodilator) and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Combimeg CFC Free Inhaler 120 MDI

  • Nausea
  • Vomiting
  • Respiratory tract infection
  • Headache
  • Sore throat
  • Cough
  • Bone, muscle or joint pain
  • Increased heart rate
  • Chills
  • Black or tarry stools
  • Noisy breathing

What if I have taken an overdose of Combimeg CFC Free Inhaler 120 MDI

Do not use Combimeg CFC Free Inhaler 120 MDI in more doses or more often than prescribed as it may cause overdose. The symptoms of overdose include chest pain, dry mouth, confusion, decreased urine output, loss of appetite, high blood pressure, nervousness or mood changes. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not stop taking this medicine of your own unless advised by your doctor. Before taking Combimeg CFC Free Inhaler 120 MDI, let your doctor know if have a history of heart, liver, kidney diseases, hyperadrenocorticism (high levels of cortisol), eye disorders like cataracts and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes. Combimeg CFC Free Inhaler 120 MDI causes hypokalemia (low potassium levels in the blood), therefore should be used with caution in patients with hypokalaemia to prevent any cardiovascular effects.  Special precautions should be taken in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis since nasal or inhaled corticosteroids like Fluticasone can cause secondary infections. Combimeg CFC Free Inhaler 120 MDI can cause a rise in blood glucose levels. Hence monitor your blood glucose levels regularly if you are diabetic. Please let your doctor know if you plan to become pregnant or are already pregnant and a lactating mother. Do not drive or operate machinery if you experience drowsiness and increased/uneven heart rate while using Combimeg CFC Free Inhaler 120 MDI. Avoid drinking alcohol while taking this medicine as it can worsen your side effects.

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
SalmeterolClarithromycin
Severe

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
Co-administration of Combimeg CFC Free Inhaler 120 MDI with Mifepristone may make Combimeg CFC Free Inhaler 120 MDI less effective as a therapy.

How to manage the interaction:
Taking Combimeg CFC Free Inhaler 120 MDI with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
SalmeterolClarithromycin
Severe
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
Taking Clarithromycin may boost the blood levels of Combimeg CFC Free Inhaler 120 MDI increasing the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Combimeg CFC Free Inhaler 120 MDI if prescribed by the doctor. Consult the prescriber if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. Do not stop using any medications without a doctor's advice.
SalmeterolPropranolol
Severe
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
Using propranolol together with Combimeg CFC Free Inhaler 120 MDI may reduce the benefits of both medications, since they have opposing effects in the body. In addition, propranolol can sometimes cause breathing problems.

How to manage the interaction:
Although taking Propranolol together with Combimeg CFC Free Inhaler 120 MDI can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
SalmeterolCarvedilol
Severe
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
Taking Carvedilol and Combimeg CFC Free Inhaler 120 MDI may reduce the effects of both medications.

How to manage the interaction:
There may be a possibility of interaction between Combimeg CFC Free Inhaler 120 MDI and Carvedilol, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
SalmeterolAmprenavir
Severe
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
Co-administration of Amprenavir and Combimeg CFC Free Inhaler 120 MDI together can increase the irregular heart rhythm.

How to manage the interaction:
Although taking Combimeg CFC Free Inhaler 120 MDI and Amprenavir together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
SalmeterolCocaine
Severe
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
Using Combimeg CFC Free Inhaler 120 MDI together with cocaine nasal may occasionally cause irregular heart rhythm.

How to manage the interaction:
Co-administration of Combimeg CFC Free Inhaler 120 MDI with Cocaine can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
SalmeterolIdelalisib
Severe
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
The combined use of Idelalisib and Combimeg CFC Free Inhaler 120 MDI can increase the risk of irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Combimeg CFC Free Inhaler 120 MDI and Idelalisib, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
SalmeterolBoceprevir
Severe
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
Co-administration of Boceprevir and Combimeg CFC Free Inhaler 120 MDI together can increase the irregular heart rhythm.

How to manage the interaction:
Although taking Combimeg CFC Free Inhaler 120 MDI and Boceprevir together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SalmeterolNelfinavir
Severe
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
Nelfinavir may significantly increase the blood levels of Combimeg CFC Free Inhaler 120 MDI. High blood levels of Combimeg CFC Free Inhaler 120 MDI can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Combimeg CFC Free Inhaler 120 MDI with Nelfinavir can result in an interaction, but it can be taken if your doctor has advised it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
SalmeterolTimolol
Severe
How does the drug interact with Combimeg CFC Free Inhaler 120 MDI:
Co-administration of Combimeg CFC Free Inhaler 120 MDI with Timolol can decrease the action of both the medications, can increase the risk or severity of side effects including increased risk of asthma, breathing problems.

How to manage the interaction:
Although taking Combimeg CFC Free Inhaler 120 MDI and timolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Combimeg CFC Free Inhaler 120 MDI.

  • Know your triggers like allergens, such as pollen, dust, and food items that make your asthma severe.

  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.

  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Combimeg CFC Free Inhaler 120 MDI Substitute

Substitutes safety advice
  • Seroflo 250 Synchrobreathe

    by AYUR

    7.58per tablet
  • Combitide 250 Inhaler 120 mdi

    5.86per tablet
  • Airtec SF 250 Inhaler 150 MDI

    1.46per tablet
  • COMBITIDE 250MCG STARHALER

    657.00per tablet
  • Forair 250 HFA Inhaler 120 mdi

    6.29per tablet
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Alcohol

Caution

Avoid drinking alcohol while taking this medicine as it can worsen your side effects.

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Pregnancy

Caution

Please consult your doctor if you are planning to conceive or are already pregnant before starting Combimeg CFC Free Inhaler 120 MDI.

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Breast Feeding

Caution

There is limited data on how Combimeg CFC Free Inhaler 120 MDI affects breastfeeding. Please consult your doctor before starting Combimeg CFC Free Inhaler 120 MDI.

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Driving

Caution

Do not drive or operate machinery if you experience drowsiness and increased/uneven heart rate while using Combimeg CFC Free Inhaler 120 MDI. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Combimeg CFC Free Inhaler 120 MDI should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Combimeg CFC Free Inhaler 120 MDI.

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Kidney

Caution

Combimeg CFC Free Inhaler 120 MDI should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Combimeg CFC Free Inhaler 120 MDI.

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Children

Caution

Combimeg CFC Free Inhaler 120 MDI is not recommended for use for children less than four years of age. The dose may have to be adjusted by your doctor depending upon the condition of the child's disease and age.

FAQs

Combimeg CFC Free Inhaler 120 MDI is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD).
Combimeg CFC Free Inhaler 120 MDI is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). Combimeg CFC Free Inhaler 120 MDI consists of Salmeterol (bronchodilator) and Fluticasone (Fluticasone). Salmeterol relaxes the muscles in the airways and increases airflow to the lungs. Fluticasone acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.
Combimeg CFC Free Inhaler 120 MDI should be cautiously administered under the doctor's guidance in seizures since bronchodilators like Salmeterol can cause central nervous system stimulation that can lead to other adverse conditions. Please consult your doctor before using Combimeg CFC Free Inhaler 120 MDI if you have seizures.
Combimeg CFC Free Inhaler 120 MDI contains bronchodilator (Fluticasone), which can cause a rise in blood glucose levels. Hence therapy with Combimeg CFC Free Inhaler 120 MDI is cautiously administered in patients with diabetes. Please monitor your blood glucose levels regularly and inform your doctor so that the dose can be adjusted accordingly.
Bronchodilator (Salmeterol) in Combimeg CFC Free Inhaler 120 MDI may decrease the potassium levels in your body, therefore should be used with caution. Please consult your doctor before taking Combimeg CFC Free Inhaler 120 MDI since low potassium levels can lead to other cardiovascular problems in patients with hypokalaemia.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Country of origin

India

Manufacturer/Marketer address

No. 1065, Street No. 1, Haripur, Sector - 4,, Panchkula, 160022.
Other Info - COM0841

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